Piperidine dispiro-1,2,4-trioxane analogues

Bioorganic and Medicinal Chemistry Letters

Volumn 18, Issue 21, 2008, Pages 5804-5808

  Sabbani, Sunil ^a   Stocks, Paul A ^b   Ellis, Gemma L ^b   Davies, Jill ^c   Hedenstrom, Erik ^a   Ward, Stephen A ^c   O'Neill, Paul M ^b  

^a MID SWEDEN UNIVERSITY   (Sweden)

^b UNIVERSITY OF LIVERPOOL   (United Kingdom)

^c LIVERPOOL SCHOOL OF TROPICAL MEDICINE   (United Kingdom)

Author keywords

1,2,4 Trioxane; Antimalarial; Endoperoxide; Hydrogen peroxide; Mechanism of action

Indexed keywords

1,2,4 TRIOXANE DERIVATIVE; 2 ADAMANTANONE DERIVATIVE; ARTEMETHER; ARTEMISININ; ENDOPEROXIDE; PIPERIDINE DISPIRO 1,2,4 TRIOXANE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIMALARIAL ACTIVITY; ARTICLE; COREY CHAYKOVSKY EPOXIDATION; DEPROTECTION REACTION; DRUG MECHANISM; DRUG STRUCTURE; DRUG SYNTHESIS; EPOXIDATION; HYDROLYSIS; IC 50; NONHUMAN; PLASMODIUM FALCIPARUM;

ANIMALS; ANTIMALARIALS; CHROMATOGRAPHY, THIN LAYER; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; PIPERIDINES; PLASMODIUM FALCIPARUM;

PLASMODIUM FALCIPARUM;

EID: 54049135939     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2008.09.052     Document Type: Article

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