Dispiro-1,2,4-trioxane analogues of a prototype dispiro-1,2,4-trioxolane: Mechanistic comparators for artemisinin in the context of reaction pathways with iron(II)

Journal of Organic Chemistry

Volumn 70, Issue 13, 2005, Pages 5103-5110

  Tang, Yuanqing ^a   Dong, Yuxiang ^a   Wang, Xiaofang ^a   Sriraghavan, Kamaraj ^a   Wood, James K ^b   Vennerstrom, Jonathan L ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b UNIVERSITY OF NEBRASKA AT OMAHA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BROMINE; CARBON; FREE RADICAL POLYMERIZATION; MALARIA CONTROL; STEREOCHEMISTRY;

ANTIMALARIAL ACTIVITY; CARBON-CENTERED RADICALS; SINGLE ELECTRON REDUCTION;

SOFTWARE PROTOTYPING;

ADAMANTANE 2 SPIRO 3' 1',2',4' TRIOXASPIRO UNDECANE; ADAMANTANE 2 SPIRO 3' 1',2',5' TRIOXASPIRO UNDECANE; ADAMANTANE DERIVATIVE; ARTEMISININ; BROMINE DERIVATIVE; DISPIRO 1,2,4 TRIOXANE; DISPIRO 1,2,4 TRIOXOLANE; FERROUS ION; OXOLINIC ACID; OXYGEN; UNCLASSIFIED DRUG;

ANTIMALARIAL ACTIVITY; ARTICLE; ATOM; CHEMICAL BOND; ENTROPY; REACTION ANALYSIS;

ADAMANTANE; ANIMALS; ANTIMALARIALS; ARTEMISININS; CATALYSIS; IRON; MOLECULAR STRUCTURE; PLASMODIUM BERGHEI; PLASMODIUM FALCIPARUM; SESQUITERPENES; SPIRO COMPOUNDS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 20844440050     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo050385+     Document Type: Article

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