Evidence for a pfcrt-associated chloroquine efflux system in the human malarial parasite Plasmodium falciparum

Biochemistry

Volumn 44, Issue 29, 2005, Pages 9862-9870

  Sanchez, Cecilia P ^a   McLean, Jeremy E ^a   Rohrbach, Petra ^a   Fidock, David A ^b   Stein, Wilfred D ^c   Lanzer, Michael ^a  

^a UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^c HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

CONCENTRATION (PROCESS); DRUG THERAPY; GENES; HUMAN ENGINEERING; PUMPS; SUBSTRATES;

EFFLUX PUMPS; MULTIDRUG RESISTANCE; RESISTANT CELLS; TRANS SIDE;

MALARIA CONTROL;

CHLOROQUINE;

ALLELISM; ARTICLE; DRUG ACCUMULATION; GENE; GENETIC POLYMORPHISM; MALARIA; MEMBRANE TRANSPORT; MOLECULAR CLONING; MULTIDRUG RESISTANCE; NONHUMAN; PFCRT GENE; PHENOTYPE; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL;

ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; CARRIER PROTEINS; CHLOROQUINE; DRUG RESISTANCE; ERYTHROCYTE MEMBRANE; FOOD; HUMANS; MEMBRANE PROTEINS; MEMBRANE TRANSPORT PROTEINS; OXAZOLES; PLASMODIUM FALCIPARUM; POLYMORPHISM, GENETIC; PROTOZOAN PROTEINS; SPECIES SPECIFICITY; SPECTROMETRY, FLUORESCENCE; VACUOLES;

PLASMODIUM FALCIPARUM;

EID: 22744436592     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi050061f     Document Type: Article

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