Development of artemisinin and its structurally simplified trioxane derivatives as antimalarial drugs

Acta Tropica

Volumn 89, Issue 3, 2004, Pages 329-342

  Ploypradith, Poonsakdi ^a  

^a Toxicology and Management of Chemicals   (Thailand)

Author keywords

Artemisinin; Molecular mechanism(s) of action; Semi synthetic derivatives; Structurally simplified trioxanes

Indexed keywords

1,2,4 TRIOXANE DERIVATIVE; 10 ANHYDRODEOXOARTEMISININ DERIVATIVE; 10 CARBADEOXOARTEMISININ DERIVATIVE; 11 AZAARTEMESIN DERIVATIVE; 3 (4 CARBOXYPHENYL) 12ALPHA BENZYLOXYTRIOXANE; 3 (4 CARBOXYPHENYL) 12ALPHA PYRANOTRIOXANE; 3 (4 CARBOXYPHENYLTRIOXANE); 3 (4 FLUOROPHENOXYTRIOXANE); ANTIMALARIAL AGENT; ANTINEOPLASTIC AGENT; ARTELINIC ACID; ARTEMISIN DERIVATIVE; ARTEMISINIC ACID; CYCLOALKANE DERIVATIVE; DEOXYARTEMESIN DERIVATIVE; DIMER; ENDOPEROXIDE; EPOXIDE; ETHER DERIVATIVE; LACTAM DERIVATIVE; SULFIDE; SULFONE; UNCLASSIFIED DRUG;

MALARIA;

ANTIMALARIAL ACTIVITY; ARTICLE; DRUG ACTIVITY; DRUG BIOAVAILABILITY; DRUG EFFICACY; DRUG HALF LIFE; DRUG MECHANISM; DRUG METABOLISM; DRUG POTENCY; DRUG SCREENING; DRUG SENSITIVITY; DRUG SOLUBILITY; DRUG STABILITY; DRUG STRUCTURE; DRUG SYNTHESIS; NONHUMAN; PLASMODIUM BERGHEI; PLASMODIUM FALCIPARUM; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

EID: 1642442453     PISSN: 0001706X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.actatropica.2003.10.006     Document Type: Article

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