A single amino acid residue can determine the sensitivity of SERCAs to artemisinins

Nature Structural and Molecular Biology

Volumn 12, Issue 7, 2005, Pages 628-629

  Uhlemann, Anne Catrin ^a   Cameron, Angus ^b   Eckstein Ludwig, Ursula ^a   Fischbarg, Jorge ^c   Iserovich, Pavel ^c   Zuniga, Felipe A ^c   East, Malcolm ^d   Lee, Anthony ^d   Brady, Leo ^b   Haynes, Richard K ^e   Krishna, Sanjeev ^a  

^a ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

^b UNIVERSITY OF BRISTOL   (United Kingdom)

^c Columbia University ^*  (United States)

^d UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^e HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM); AMINO ACID; ANTIMALARIAL AGENT; ARTEMISIN DERIVATIVE; ARTEMISININ; ARTEMISONE; SESQUITERPENE LACTONE; THAPSIGARGIN; UNCLASSIFIED DRUG;

ARTICLE; DRUG BINDING SITE; DRUG SENSITIVITY; IC 50; NONHUMAN; PLASMODIUM; PLASMODIUM BERGHEI; PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PRIORITY JOURNAL; SEQUENCE ALIGNMENT; XENOPUS LAEVIS;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; ARTEMISININS; CALCIUM-TRANSPORTING ATPASES; DRUG RESISTANCE; MITOCHONDRIAL PROTON-TRANSLOCATING ATPASES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; OOCYTES; PLASMODIUM FALCIPARUM; SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES; SEQUENCE ALIGNMENT; XENOPUS LAEVIS;

MAMMALIA; PLASMODIUM BERGHEI; PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; XENOPUS LAEVIS;

EID: 22144461405     PISSN: 15459993     EISSN: None     Source Type: Journal    
DOI: 10.1038/nsmb947     Document Type: Article

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