-
1
-
-
33845433407
-
20th Report
-
WHO Expert Committee on Malaria
-
WHO Expert Committee on Malaria: 20th Report. WHO Tech Rep Ser (2000):892-976.
-
(2000)
WHO Tech Rep Ser
, pp. 892-976
-
-
-
2
-
-
0030879643
-
Haematin (haem) polymerization and its inhibition by quinoline antimalarials
-
Ridley RG, Dorn A, Vippagunta SR, Vennerstrom JL: Haematin (haem) polymerization and its inhibition by quinoline antimalarials. Ann Trop Med Parasitol (1997) 91(5):559-566.
-
(1997)
Ann Trop Med Parasitol
, vol.91
, Issue.5
, pp. 559-566
-
-
Ridley, R.G.1
Dorn, A.2
Vippagunta, S.R.3
Vennerstrom, J.L.4
-
3
-
-
68549108583
-
-
Goodwin LG: Chemotherapy and tropical disease: The problem and the challenge. In: Chemotherapy of Tropical Diseases: Critical Reports on Applied Chemistry. Hooper M (Ed), John Wiley & Sons, Chichester, UK (1987) 21:1-18.
-
Goodwin LG: Chemotherapy and tropical disease: The problem and the challenge. In: Chemotherapy of Tropical Diseases: Critical Reports on Applied Chemistry. Hooper M (Ed), John Wiley & Sons, Chichester, UK (1987) 21:1-18.
-
-
-
-
4
-
-
0023693494
-
Introduction of halofantrine for malaria treatment
-
Horton RJ: Introduction of halofantrine for malaria treatment. Parasitology Today (1988) 4:238-239.
-
(1988)
Parasitology Today
, vol.4
, pp. 238-239
-
-
Horton, R.J.1
-
5
-
-
0002363677
-
Antimalarial hydroxynaphthoquinones
-
Leeming PR Ed, Royal Society of Chemistry, London, UK
-
Hudson AT: Antimalarial hydroxynaphthoquinones. In: Topics in Medicinal Chemistry. Special publication No 65. Leeming PR (Ed), Royal Society of Chemistry, London, UK (1988):266-283.
-
(1988)
Topics in Medicinal Chemistry. Special publication No 65
, pp. 266-283
-
-
Hudson, A.T.1
-
6
-
-
0025040534
-
The prevention of antimalarial resistance
-
Peters W: The prevention of antimalarial resistance. Pharmacol Ther (1990) 47(3):499-508.
-
(1990)
Pharmacol Ther
, vol.47
, Issue.3
, pp. 499-508
-
-
Peters, W.1
-
7
-
-
0023156693
-
Combination treatment for falciparum prophylaxis
-
White NJ: Combination treatment for falciparum prophylaxis. Lancet (1987) 1(8534):680-681.
-
(1987)
Lancet
, vol.1
, Issue.8534
, pp. 680-681
-
-
White, N.J.1
-
8
-
-
0022611535
-
Severe cutaneous reactions among American travelers using pyrimethamine-sulfadoxine (Fansidar) for malaria prophylaxis
-
Miller KD, Lobel HO, Satriale RF, Kuritsky JN, Stern R, Campbell CC: Severe cutaneous reactions among American travelers using pyrimethamine-sulfadoxine (Fansidar) for malaria prophylaxis. Am J Trop Med Hyg (1986) 35(3):451-458.
-
(1986)
Am J Trop Med Hyg
, vol.35
, Issue.3
, pp. 451-458
-
-
Miller, K.D.1
Lobel, H.O.2
Satriale, R.F.3
Kuritsky, J.N.4
Stern, R.5
Campbell, C.C.6
-
9
-
-
0034964979
-
Recent advances in the chemistry of cyclic peroxides
-
McCullough KJ, Nojima M: Recent advances in the chemistry of cyclic peroxides. Curr Org Chem (2001) 5(6):601-636.
-
(2001)
Curr Org Chem
, vol.5
, Issue.6
, pp. 601-636
-
-
McCullough, K.J.1
Nojima, M.2
-
10
-
-
0030879877
-
Peroxidic antimalarials
-
Testa B, Meyer UA Eds, Academic Press, Harcourt Brace and Company, London, UK
-
Jefford CW: Peroxidic antimalarials. In: Advances in Drug Research. Testa B, Meyer UA (Eds), Academic Press, Harcourt Brace and Company, London, UK (1997) 29:271- 325.
-
(1997)
Advances in Drug Research
, vol.29
, pp. 271-325
-
-
Jefford, C.W.1
-
11
-
-
0035207181
-
Why artemisinin and certain synthetic peroxides are potent antimalarials. Implications for the mode of action
-
Jefford CW: Why artemisinin and certain synthetic peroxides are potent antimalarials. Implications for the mode of action. Curr Med Chem (2001) 8(15):1803-1826.
-
(2001)
Curr Med Chem
, vol.8
, Issue.15
, pp. 1803-1826
-
-
Jefford, C.W.1
-
12
-
-
0030051699
-
Secondgeneration antimalarial endoperoxides
-
Meshnick SR, Jefford CW, Posner GH, Avery MA, Peters W: Secondgeneration antimalarial endoperoxides. Parasitol Today (1996) 12(2):79-82.
-
(1996)
Parasitol Today
, vol.12
, Issue.2
, pp. 79-82
-
-
Meshnick, S.R.1
Jefford, C.W.2
Posner, G.H.3
Avery, M.A.4
Peters, W.5
-
13
-
-
0034092110
-
Recent developments in the chemotherapy of malaria
-
Bell A: Recent developments in the chemotherapy of malaria. Curr Opin Anti-Infective Invest Drugs (2000) 2(1):63-70.
-
(2000)
Curr Opin Anti-Infective Invest Drugs
, vol.2
, Issue.1
, pp. 63-70
-
-
Bell, A.1
-
14
-
-
0032969901
-
Current progress in the chemistry, medicinal chemistry and drug design of artemisininbased antimalarials
-
Vroman JA, Alvim-Gaston M, Avery MA: Current progress in the chemistry, medicinal chemistry and drug design of artemisininbased antimalarials. Curr Pharm Design (1999) 5(2):101-138.
-
(1999)
Curr Pharm Design
, vol.5
, Issue.2
, pp. 101-138
-
-
Vroman, J.A.1
Alvim-Gaston, M.2
Avery, M.A.3
-
15
-
-
0033165891
-
Recent developments on the chemistry and biological activity of artemisinin and related antimalarials - an update
-
Bhattacharya AK, Sharma RP: Recent developments on the chemistry and biological activity of artemisinin and related antimalarials - an update. Heterocycles (1999) 51:1681-1745.
-
(1999)
Heterocycles
, vol.51
, pp. 1681-1745
-
-
Bhattacharya, A.K.1
Sharma, R.P.2
-
16
-
-
0001909180
-
Current developments in the chemistry of artemisinin and related compounds
-
Jung M: Current developments in the chemistry of artemisinin and related compounds. Curr Med Chem (1994) 1:35-49.
-
(1994)
Curr Med Chem
, vol.1
, pp. 35-49
-
-
Jung, M.1
-
18
-
-
0027770863
-
Synthesis, structure, and antimalarial activity of tricyclic 1,2,4-trioxanes related to artemisinin
-
Jefford CW, Velarde JA, Bernardinelli G, Bray DH, Warhurst DC, Milhous WK: Synthesis, structure, and antimalarial activity of tricyclic 1,2,4-trioxanes related to artemisinin. Helv Chim Acta (1993) 76:2775-2788.
-
(1993)
Helv Chim Acta
, vol.76
, pp. 2775-2788
-
-
Jefford, C.W.1
Velarde, J.A.2
Bernardinelli, G.3
Bray, D.H.4
Warhurst, D.C.5
Milhous, W.K.6
-
19
-
-
0032510451
-
Orally active antimalarial 3-substituted trioxanes: New synthetic methodology and biological evaluation
-
Posner GH, Cumming JN, Woo SH, Ploypradith P, Xie S, Shapiro TA: Orally active antimalarial 3-substituted trioxanes: New synthetic methodology and biological evaluation. J Med Chem (1998) 41(6):940-951.
-
(1998)
J Med Chem
, vol.41
, Issue.6
, pp. 940-951
-
-
Posner, G.H.1
Cumming, J.N.2
Woo, S.H.3
Ploypradith, P.4
Xie, S.5
Shapiro, T.A.6
-
20
-
-
0035855920
-
Antimalarial simplified 3-aryltrioxanes: Synthesis and preclinical efficacy/toxicity testing in rodents
-
Posner GH, Jeon HB, Parker MH, Krasavin M, Paik I, Shapiro TA: Antimalarial simplified 3-aryltrioxanes: Synthesis and preclinical efficacy/toxicity testing in rodents. J Med Chem (2001) 44(19):3054-3058.
-
(2001)
J Med Chem
, vol.44
, Issue.19
, pp. 3054-3058
-
-
Posner, G.H.1
Jeon, H.B.2
Parker, M.H.3
Krasavin, M.4
Paik, I.5
Shapiro, T.A.6
-
21
-
-
0028293959
-
New, antimalarial, tricyclic 1,2,4-trioxanes: Evaluations in mice and monkeys
-
Posner GH, Oh CH, Webster HK, Ager AL Jr, Rossan RN: New, antimalarial, tricyclic 1,2,4-trioxanes: Evaluations in mice and monkeys. Am J Trop Med Hyg (1994) 50(4):522-526.
-
(1994)
Am J Trop Med Hyg
, vol.50
, Issue.4
, pp. 522-526
-
-
Posner, G.H.1
Oh, C.H.2
Webster, H.K.3
Ager Jr, A.L.4
Rossan, R.N.5
-
22
-
-
0029061802
-
Structure-activity relationships of lactone ring-opened analogs of the antimalarial 1,2,4-trioxane artemisinin
-
Posner GH, McGarvey DJ, Oh CH, Kumar N, Meshnick SR, Asawamahasadka W: Structure-activity relationships of lactone ring-opened analogs of the antimalarial 1,2,4-trioxane artemisinin. J Med Chem (1995) 38(4):607-612.
-
(1995)
J Med Chem
, vol.38
, Issue.4
, pp. 607-612
-
-
Posner, G.H.1
McGarvey, D.J.2
Oh, C.H.3
Kumar, N.4
Meshnick, S.R.5
Asawamahasadka, W.6
-
23
-
-
0028170770
-
Ro 42-1611 (arteflene), a new effective antimalarial: Chemical structure and biological activity
-
Hofheinz W, Bürgin H, Gocke E, Jaquet C, Masciadri R, Schmid G, Stohler H, Urwyler H: Ro 42-1611 (arteflene), a new effective antimalarial: Chemical structure and biological activity. Trop Med Parasitol (1994) 45(3):261-265.
-
(1994)
Trop Med Parasitol
, vol.45
, Issue.3
, pp. 261-265
-
-
Hofheinz, W.1
Bürgin, H.2
Gocke, E.3
Jaquet, C.4
Masciadri, R.5
Schmid, G.6
Stohler, H.7
Urwyler, H.8
-
24
-
-
0028170768
-
Efficacy of Ro 42-1611 (arteflene) in the treatment of patients with mild malaria: A clinical trial in Cameroon
-
Somo-Moyou R, Mittelholzer ML, Sorenson F, Haller L, Stürchler D: Efficacy of Ro 42-1611 (arteflene) in the treatment of patients with mild malaria: A clinical trial in Cameroon. Trop Med Parasitol (1994) 45(3):288-291.
-
(1994)
Trop Med Parasitol
, vol.45
, Issue.3
, pp. 288-291
-
-
Somo-Moyou, R.1
Mittelholzer, M.L.2
Sorenson, F.3
Haller, L.4
Stürchler, D.5
-
25
-
-
0032514426
-
A carbonyl oxide route to antimalarial yingzhaosu A analogues: Synthesis and antimalarial activity
-
O'Neill PM, Searle NL, Raynes KJ, Maggs JL, Ward SA, Storr RC, Park BK, Posner GH: A carbonyl oxide route to antimalarial yingzhaosu A analogues: Synthesis and antimalarial activity. Tetrahedron Lett (1998) 39(33):6065-6068.
-
(1998)
Tetrahedron Lett
, vol.39
, Issue.33
, pp. 6065-6068
-
-
O'Neill, P.M.1
Searle, N.L.2
Raynes, K.J.3
Maggs, J.L.4
Ward, S.A.5
Storr, R.C.6
Park, B.K.7
Posner, G.H.8
-
26
-
-
0032554709
-
Synthesis and in vitro antimalarial activity of sulfone endoperoxides
-
Bachi MD, Korshin EE, Ploypradith P, Cumming JN, Xie S, Shapiro TA, Posner GH: Synthesis and in vitro antimalarial activity of sulfone endoperoxides. Biorg Med Chem Lett (1998) 8(8):903-908.
-
(1998)
Biorg Med Chem Lett
, vol.8
, Issue.8
, pp. 903-908
-
-
Bachi, M.D.1
Korshin, E.E.2
Ploypradith, P.3
Cumming, J.N.4
Xie, S.5
Shapiro, T.A.6
Posner, G.H.7
-
27
-
-
0037057574
-
Antimalarial activity of yingzhaosu A analogues
-
Kim HS, Begum K, Ogura N, Wataya Y, Tokuyasu T, Masuyama A, Nojima M, McCullough KJ: Antimalarial activity of yingzhaosu A analogues. J Med Chem (2002) 45(21):4732-4736.
-
(2002)
J Med Chem
, vol.45
, Issue.21
, pp. 4732-4736
-
-
Kim, H.S.1
Begum, K.2
Ogura, N.3
Wataya, Y.4
Tokuyasu, T.5
Masuyama, A.6
Nojima, M.7
McCullough, K.J.8
-
28
-
-
0035833052
-
Yingzhaosu A analogues: Synthesis by the ozonolysis of unsaturated hydroperoxides, structural analysis and determination of antimalarial activity
-
Tokuyasu T, Masuyama A, Nojima M, McCullough KJ, Kim H-S, Wataya Y: Yingzhaosu A analogues: Synthesis by the ozonolysis of unsaturated hydroperoxides, structural analysis and determination of antimalarial activity. Tetrahedron (2001) 57(28):5979-5989.
-
(2001)
Tetrahedron
, vol.57
, Issue.28
, pp. 5979-5989
-
-
Tokuyasu, T.1
Masuyama, A.2
Nojima, M.3
McCullough, K.J.4
Kim, H.-S.5
Wataya, Y.6
-
29
-
-
0029142546
-
Synthesis, structure, and antimalarial activity of some enantiomerically pure cis-fused cyclopenteno-1,2,4-trioxanes
-
Jefford CW, Kohmoto S, Jaggi D, Timári G, Rossier JC, Rudaz M, Barbuzzi O, Gérard D, Burger U, Kamalaprija P, Mareda J et al: Synthesis, structure, and antimalarial activity of some enantiomerically pure cis-fused cyclopenteno-1,2,4-trioxanes. Helv Chim Acta (1995) 78:647-662.
-
(1995)
Helv Chim Acta
, vol.78
, pp. 647-662
-
-
Jefford, C.W.1
Kohmoto, S.2
Jaggi, D.3
Timári, G.4
Rossier, J.C.5
Rudaz, M.6
Barbuzzi, O.7
Gérard, D.8
Burger, U.9
Kamalaprija, P.10
Mareda, J.11
-
30
-
-
0031042849
-
The chemotherapy of rodent malaria. LIII. 'Fenozan BO7 (Fenozan-50F), a difluorinated 3,3′-spirocyclopentane- 1,2,4-trioxane: Comparison with some compounds of the artemisinin series
-
Fleck SL, Robinson BL, Peters W, Thévin F, Boulard Y, Glénat C, Caillard V, Landau I: The chemotherapy of rodent malaria. LIII. 'Fenozan BO7 (Fenozan-50F), a difluorinated 3,3′-spirocyclopentane- 1,2,4-trioxane: Comparison with some compounds of the artemisinin series. Ann Trop Med Parasitol (1997) 91(1):25-32.
-
(1997)
Ann Trop Med Parasitol
, vol.91
, Issue.1
, pp. 25-32
-
-
Fleck, S.L.1
Robinson, B.L.2
Peters, W.3
Thévin, F.4
Boulard, Y.5
Glénat, C.6
Caillard, V.7
Landau, I.8
-
31
-
-
0028120927
-
The interaction of artemisinin with malarial hemozoin
-
Hong YL, Yang YZ, Meshnick SR: The interaction of artemisinin with malarial hemozoin. Mol Biochem Parasitol (1994) 63(1):121-128.
-
(1994)
Mol Biochem Parasitol
, vol.63
, Issue.1
, pp. 121-128
-
-
Hong, Y.L.1
Yang, Y.Z.2
Meshnick, S.R.3
-
32
-
-
0033516474
-
Artemisinin, an endoperoxide antimalarial, disrupts the hemoglobin catabolism and heme detoxification systems in malarial parasite
-
Pandey AV, Tekwani BL, Singh RL, Chauhan VS: Artemisinin, an endoperoxide antimalarial, disrupts the hemoglobin catabolism and heme detoxification systems in malarial parasite. J Biol Chem (1999) 274(27):19383-19388.
-
(1999)
J Biol Chem
, vol.274
, Issue.27
, pp. 19383-19388
-
-
Pandey, A.V.1
Tekwani, B.L.2
Singh, R.L.3
Chauhan, V.S.4
-
33
-
-
0023756247
-
Synthesis of new 1,2,4-trioxanes and their antimalarial activity
-
Jefford CW, McGoran EC, Boukouvalas J, Richardson G, Robinsion BL, Peters W: Synthesis of new 1,2,4-trioxanes and their antimalarial activity. Helv Chim Acta (1988) 71:1805-1812.
-
(1988)
Helv Chim Acta
, vol.71
, pp. 1805-1812
-
-
Jefford, C.W.1
McGoran, E.C.2
Boukouvalas, J.3
Richardson, G.4
Robinsion, B.L.5
Peters, W.6
-
34
-
-
0034681067
-
Preparation and antimalarial activities of 'trioxaquines', new modular molecules with a trioxane skeleton linked to a 4-aminoquinoline
-
Dechy-Cabaret O, Benoit-Vical F, Robert A, Meunier B: Preparation and antimalarial activities of 'trioxaquines', new modular molecules with a trioxane skeleton linked to a 4-aminoquinoline. ChemBioChem (2000) 1(4):281-283.
-
(2000)
ChemBioChem
, vol.1
, Issue.4
, pp. 281-283
-
-
Dechy-Cabaret, O.1
Benoit-Vical, F.2
Robert, A.3
Meunier, B.4
-
35
-
-
0034163723
-
The structure and antimalarial activity of some 1,2,4-trioxanes, 1,2,4,5-tetroxanes, and bicyclic endoperoxides: Implications for the mode of action
-
Jefford CW, Rossier JC, Milhous WK: The structure and antimalarial activity of some 1,2,4-trioxanes, 1,2,4,5-tetroxanes, and bicyclic endoperoxides: Implications for the mode of action. Heterocycles (2000) 52:1345-1352.
-
(2000)
Heterocycles
, vol.52
, pp. 1345-1352
-
-
Jefford, C.W.1
Rossier, J.C.2
Milhous, W.K.3
-
36
-
-
68549106761
-
Antimalarial synthesis. Annual Technical report No AM- 1A-73
-
Doorenbos HE, Decker DL: Antimalarial synthesis. Annual Technical report No AM- 1A-73. The Dow Chemical Company (1973):14.
-
(1973)
The Dow Chemical Company
, pp. 14
-
-
Doorenbos, H.E.1
Decker, D.L.2
-
37
-
-
0026746330
-
-
Vennerstrom JL, Fu H-N, Ellis WY, Ager AL Jr, Wood JK, Andersen SL, Gerena L, Milhous WK: Dispiro-1,2,4,5-tetraoxanes: A new class of antimalarial peroxides. J Med Chem (1992) 35(16):3023-3027.
-
Vennerstrom JL, Fu H-N, Ellis WY, Ager AL Jr, Wood JK, Andersen SL, Gerena L, Milhous WK: Dispiro-1,2,4,5-tetraoxanes: A new class of antimalarial peroxides. J Med Chem (1992) 35(16):3023-3027.
-
-
-
-
38
-
-
18744417592
-
-
Vennerstrom JL, Dong Y, Andersen SL, Ager AL Jr, Fu H, Miller RE, Wesche DL, Kyle DE, Gerena L, Walters SM, Wood JK et al: Synthesis and antimalarial activity of sixteen dispiro-1,2,4,5-tetraoxanes: Alkyl-substituted 7,8,15,16-tetraoxadispiro[5.2.5.2]hexadecanes. J Med Chem (2000) 43(14):2753-2758.
-
Vennerstrom JL, Dong Y, Andersen SL, Ager AL Jr, Fu H, Miller RE, Wesche DL, Kyle DE, Gerena L, Walters SM, Wood JK et al: Synthesis and antimalarial activity of sixteen dispiro-1,2,4,5-tetraoxanes: Alkyl-substituted 7,8,15,16-tetraoxadispiro[5.2.5.2]hexadecanes. J Med Chem (2000) 43(14):2753-2758.
-
-
-
-
39
-
-
0033594440
-
-
Dong Y, Matile H, Chollet J, Kaminsky R, Wood JK, Vennerstrom JL: Synthesis and antimalarial activity of 11 dispiro-1,2,4,5-tetraoxane analogues of WR 148999. 7,8,15,16-Tetraoxadispiro[5.2.5.2]-hexadecanes substituted at the 1 and 10 positions with unsaturated and polar functional groups. J Med Chem (1999) 42(8):1477-1480.
-
Dong Y, Matile H, Chollet J, Kaminsky R, Wood JK, Vennerstrom JL: Synthesis and antimalarial activity of 11 dispiro-1,2,4,5-tetraoxane analogues of WR 148999. 7,8,15,16-Tetraoxadispiro[5.2.5.2]-hexadecanes substituted at the 1 and 10 positions with unsaturated and polar functional groups. J Med Chem (1999) 42(8):1477-1480.
-
-
-
-
40
-
-
0033566212
-
-
Kim HS, Shibata Y, Wataya Y, Tsuchiya K, Masuyama A, Nojima M: Synthesis and antimalarial activity of cyclic peroxides, 1,2,4,5,7- pentoxocanes and 1,2,4,5-tetroxanes. J Med Chem (1999) 42(14):2604-2609.
-
Kim HS, Shibata Y, Wataya Y, Tsuchiya K, Masuyama A, Nojima M: Synthesis and antimalarial activity of cyclic peroxides, 1,2,4,5,7- pentoxocanes and 1,2,4,5-tetroxanes. J Med Chem (1999) 42(14):2604-2609.
-
-
-
-
41
-
-
0035811454
-
-
Kim HS, Nagai Y, Ono K, Begum K, Wataya Y, Hamada Y, Tsuchiya, K, Masuyama A, Nojima M, McCullough KJ: Synthesis and antimalarial activity of novel medium-sized 1,2,4,5-tetraoxacycloalkanes. J Med Chem (2001) 44(14):2357-2361.
-
Kim HS, Nagai Y, Ono K, Begum K, Wataya Y, Hamada Y, Tsuchiya, K, Masuyama A, Nojima M, McCullough KJ: Synthesis and antimalarial activity of novel medium-sized 1,2,4,5-tetraoxacycloalkanes. J Med Chem (2001) 44(14):2357-2361.
-
-
-
-
42
-
-
0037075833
-
Synthesis and notable antimalarial activity of acyclic peroxides, 1-(alkyldioxy)-1-(methyldioxy)cyclododecanes
-
Hamada Y, Tokuhara H, Masuyama A, Nojima M, Kim HS, Ono K, Ogura N, Wataya Y: Synthesis and notable antimalarial activity of acyclic peroxides, 1-(alkyldioxy)-1-(methyldioxy)cyclododecanes. J Med Chem (2002) 45(6):1374-1378.
-
(2002)
J Med Chem
, vol.45
, Issue.6
, pp. 1374-1378
-
-
Hamada, Y.1
Tokuhara, H.2
Masuyama, A.3
Nojima, M.4
Kim, H.S.5
Ono, K.6
Ogura, N.7
Wataya, Y.8
-
43
-
-
0035797060
-
Regioselective Mukaiyama hydroperoxysilylation of 2-alkyl- or 2-aryl-prop-2-ene-1-ols: Application to a new synthesis of 1,2,4-trioxanes
-
O'Neill PM, Pugh M, Davies J, Ward SA, Park BK: Regioselective Mukaiyama hydroperoxysilylation of 2-alkyl- or 2-aryl-prop-2-ene-1-ols: Application to a new synthesis of 1,2,4-trioxanes. Tetrahedron Lettw (2001) 42(27):4569-4571.
-
(2001)
Tetrahedron Lettw
, vol.42
, Issue.27
, pp. 4569-4571
-
-
O'Neill, P.M.1
Pugh, M.2
Davies, J.3
Ward, S.A.4
Park, B.K.5
-
44
-
-
0032482445
-
Antimalarial cyclic peroxy ketals
-
Posner GH, O'Dowd H, Ploypradith P, Cumming JN, Xie S, Shapiro TA: Antimalarial cyclic peroxy ketals. J Med Chem (1998) 41(12):2164-2167.
-
(1998)
J Med Chem
, vol.41
, Issue.12
, pp. 2164-2167
-
-
Posner, G.H.1
O'Dowd, H.2
Ploypradith, P.3
Cumming, J.N.4
Xie, S.5
Shapiro, T.A.6
-
45
-
-
0037025438
-
Photo-oxygenation of geraniol: Synthesis of a novel series of hydroxy-functionalized antimalarial 1,2,4-trioxanes
-
Singh C, Gupta N, Puri SK: Photo-oxygenation of geraniol: Synthesis of a novel series of hydroxy-functionalized antimalarial 1,2,4-trioxanes. Bioorg Med Chem Lett (2002) 12(15):1913-1916.
-
(2002)
Bioorg Med Chem Lett
, vol.12
, Issue.15
, pp. 1913-1916
-
-
Singh, C.1
Gupta, N.2
Puri, S.K.3
-
46
-
-
0037191630
-
Synthesis of antimalarial 1,2,4-trioxanes via photooxygenation of a chiral allylic alcohol
-
Griesbeck AG, El-Idressy TT, Fiege M, Brun R: Synthesis of antimalarial 1,2,4-trioxanes via photooxygenation of a chiral allylic alcohol. Org Lett (2002) 4(24):4193- 4195.
-
(2002)
Org Lett
, vol.4
, Issue.24
, pp. 4193-4195
-
-
Griesbeck, A.G.1
El-Idressy, T.T.2
Fiege, M.3
Brun, R.4
-
47
-
-
0026674545
-
Synthesis and antimalarial evaluation of 2,3,5-trioxabicyclo[2.2.2]octanes, models for the putative pharmacophore of qinghaosu (artemisinin)
-
Casteel DA, Jung KE, Gerena L, Milhous W: Synthesis and antimalarial evaluation of 2,3,5-trioxabicyclo[2.2.2]octanes, models for the putative pharmacophore of qinghaosu (artemisinin). Bioorg Med Chem (1992) 2:623-626.
-
(1992)
Bioorg Med Chem
, vol.2
, pp. 623-626
-
-
Casteel, D.A.1
Jung, K.E.2
Gerena, L.3
Milhous, W.4
-
48
-
-
0036742376
-
The chemotherapy of rodent malaria. LX. The importance of formulation in evaluating the blood schizontocidal activity of some endoperoxide antimalarials
-
Peters W, Fleck SL, Robinson BL, Stewart LB, Jefford CW: The chemotherapy of rodent malaria. LX. The importance of formulation in evaluating the blood schizontocidal activity of some endoperoxide antimalarials. Ann Trop Med Parasitol (2002) 96(6):559-573.
-
(2002)
Ann Trop Med Parasitol
, vol.96
, Issue.6
, pp. 559-573
-
-
Peters, W.1
Fleck, S.L.2
Robinson, B.L.3
Stewart, L.B.4
Jefford, C.W.5
-
49
-
-
0032812375
-
The chemotherapy of rodent malaria. LVI. Studies on the development of resistance to natural and synthetic endoperoxides
-
Peters W, Robinson BL: The chemotherapy of rodent malaria. LVI. Studies on the development of resistance to natural and synthetic endoperoxides. Ann Trop Med Parasitol (1999) 93(4):325-339.
-
(1999)
Ann Trop Med Parasitol
, vol.93
, Issue.4
, pp. 325-339
-
-
Peters, W.1
Robinson, B.L.2
-
50
-
-
0031722604
-
Safety assessment of peroxide antimalarials: Clinical and chemical perspectives
-
Park BK, O'Neil PM, Maggs JL, Pirmohamed M: Safety assessment of peroxide antimalarials: Clinical and chemical perspectives. Br J Clin Pharmacol (1998) 46(6):521-529.
-
(1998)
Br J Clin Pharmacol
, vol.46
, Issue.6
, pp. 521-529
-
-
Park, B.K.1
O'Neil, P.M.2
Maggs, J.L.3
Pirmohamed, M.4
-
51
-
-
0033035094
-
Artemisinin drugs in the treatment of malaria: From medicinal herb to registered medication
-
van Agtmael MA, Eggelte TA, van Boxtel CJ: Artemisinin drugs in the treatment of malaria: From medicinal herb to registered medication. Trends Pharmacol Sci (1999) 20(5):199-205.
-
(1999)
Trends Pharmacol Sci
, vol.20
, Issue.5
, pp. 199-205
-
-
van Agtmael, M.A.1
Eggelte, T.A.2
van Boxtel, C.J.3
-
52
-
-
0027967580
-
Animal pharmacokinetics and metabolism of the new antimalarial Ro 42-1611 (arteflene)
-
Girometta MA, Jauch R, Ponelle C, Guenzi A, Chou RC: Animal pharmacokinetics and metabolism of the new antimalarial Ro 42-1611 (arteflene). Trop Med Parasitol (1994) 45(3):272-277.
-
(1994)
Trop Med Parasitol
, vol.45
, Issue.3
, pp. 272-277
-
-
Girometta, M.A.1
Jauch, R.2
Ponelle, C.3
Guenzi, A.4
Chou, R.C.5
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