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Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 3, 2005, Pages 595-597

Novel spiroanellated 1,2,4-trioxanes with high in vitro antimalarial activities

(5) Griesbeck, Axel G a El Idreesy, Tamer T a Höinck, Lars Oliver a Lex, Johann a Brun, Reto b

a UNIVERSITY OF COLOGNE (Germany)

b SWISS TROPICAL AND PUBLIC HEALTH INSTITUTE (Switzerland)

Author keywords

Antimalarial; Peroxides; Synthesis

Indexed keywords

1,2,4 TRIOXANE DERIVATIVE; ADAMANTANE DERIVATIVE; ALCOHOL DERIVATIVE; ARTEMISININ; CHLOROQUINE; MEFLOQUINE;

ACETALIZATION; ANIMAL CELL; ANTIMALARIAL ACTIVITY; ARTICLE; CATALYSIS; CONTROLLED STUDY; DRUG STRUCTURE; NONHUMAN; PHOTOOXIDATION; RAT; STEREOCHEMISTRY;

ADAMANTANE; ANIMALS; ANTIMALARIALS; CELL DEATH; CELL LINE; HETEROCYCLIC COMPOUNDS; HUMANS; INHIBITORY CONCENTRATION 50; MOLECULAR STRUCTURE; PLASMODIUM FALCIPARUM; SPIRO COMPOUNDS; STRUCTURE-ACTIVITY RELATIONSHIP;

STAPHYLOCOCCUS PHAGE 3A;

EID: 12444281011 PISSN: 0960894X EISSN: None Source Type: Journal
DOI: 10.1016/j.bmcl.2004.11.043 Document Type: Article

Times cited : (76)

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- 2 = 0.0779. Crystallographic data for this structure have been deposited with the Cambridge Crystallographic Data Centre as supplementary publication No CCDC-241154

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