The chemotherapy of rodent malaria. LVI. Studies on the development of resistance to natural and synthetic endoperoxides

Annals of Tropical Medicine and Parasitology

Volumn 93, Issue 4, 1999, Pages 325-339

  Peters, W ^a   Robinson, B L ^a  

^a CABI   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMALARIAL AGENT; ARTEFLENE; ARTEMISININ; ARTESUNATE; CHLOROQUINE; ENDOPEROXIDE; FENOZAN B07; RO 41 3823; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG RESISTANCE; MALARIA; MALE; MOUSE; NONHUMAN; PLASMODIUM FALCIPARUM; RELAPSE; RISK; SUBCUTANEOUS DRUG ADMINISTRATION;

ANIMALIA; ARTESUNATE; PLASMODIUM BERGHEI; PLASMODIUM FALCIPARUM; PLASMODIUM YOELII; PROTOZOA; RODENTIA;

EID: 0032812375     PISSN: 00034983     EISSN: None     Source Type: Journal    
DOI: 10.1080/00034983.1999.11813429     Document Type: Article

References (23)

1. Anon. (1979). Antimalaria studies on qinghaosu. Chinese Medical Journal, 92, 811-816.
2. Asawamahasakda, W., Ittarat, I., Pu, Y. M., Ziffer, II. & Meshnick, S. R. (1994). Reaction of antimalarial endoperoxides with specific parasite proteins. Antimalarial Agents and Chemotherapy, 38, 1854-1858.
3. Avery, M. A., Alvim-Gaston, M. & Woolfrey, J. R. (1998). Synthesis and structure activity relationships of peroxidic antimalarials based on artemisinin. Advances in Medicinal Chemistry, 4, 125-217.
4. Chawira, A. N., Warhurst, D. C. & Peters, W. (1986). Qinghaosu resistance in rodent malaria. Transactions of the Royal Society of Tropical Medicine and Hygiene, 80, 477-480.
5. Cheng, L. F., Lu, L. L. & Wu, L. L. (1988). Development of artemether resistant line of Plasmodium berghei. Acta Pharmacologica Sinica, 9, 352-355.
6. Jacqet, C., Stohler, H. R., Chollet, J., Peters, W. & Bradley, D. J. (1994). Antimalarial activity of the bicyclic peroxide Ro 42- 1611 (arteflene) in experimental models. Tropical Medicine and Parasitology, 45, 266-271.
7. Jiang, G. F. (1992). In vitro development of sodium artesunate resistance in Plasmodium falciparum. Chinese Journal of Parasitology and Parasitic Diseases, 10, 37-39.
8. Li, G. F. & Zhou, Y. Q. (1991). Development of resistance to artemisinin (qinghaosu) and its derivatives by Plasmodium berghei. In Antimalarial Drug Development in China, ed. Shen, J. pp. 89-93. Beijing: National Institutes of Pharmaceutical Research and Development.
9. Liu, A. R. & Ren, Z. H. (1987). Development of a resistant line of Plasmodium berghei to sodium artesunate. Acta Pharmacologica Sinica, 8, 49-152.
10. Luxemburger, C., Brockman, A., Silamut, K., Nosten, F., van Vugt, M., Gimenez, F., Chongsuphajaisiddhi, T. & Whitte, N. J. (1998). Two patients with falciparum malaria and poor in vivo responses to artesunate. Transactions of the Royal Society of Tropical Medicine and Hygiene, 92, 668-669.
11. Peters, W. (1965). Morphological and physical variations in chloroquine-resistant Plasmodium berghei (Vincke and Lips 1948). Annales de la Société Belge de Médecine Tropicale, 45, 365-378.
12. Peters, W. (1968). The chemotherapy of rodent malaria. V. Dynamics of drug resistance. Part 1. Methods for studying the acquisition and loss of resistance to chloroquine by Plasmodium berghei. Annals of Tropical Medicine and Parasitology, 62, 277-287.
13. Peters, W. (1970). The chemotherapy of rodent malaria. X. Dynamics of drug resistance. Part 2. Acquisition and loss of chloroquine resistance in Plasmodium berghei observed in continuous bioassay. Annals of Tropical Medicine and Parasitology, 64, 25-40.
14. Peters, W. & Robinson, B. L. (1992). The chemotherapy of rodent malaria. XLVII. Studies on pyronaridine and other Mannich base antimalarials. Annals of Parasitology and Tropical Medicine, 86, 455-465.
15. Peters, W. & Robinson, B. L. (1997). The chemotherapy of rodent malaria. LV. Interactions between pyronaridine and artemisinin. Annals of Parasitology and Tropical Medicine, 91, 141-145.
16. Peters, W., Portus J. H. & Robinson, B. L. (1975). The chemotherapy of rodent malaria. XXII. The value of drug-resistant strains of P. berghei in screening for blood schizontocidal activity. Annals of Tropical Medicine and Parasitology, 69, 155-171.
17. Peters, W., Portus, J. & Robinson, B. L. (1977). The chemotherapy of rodent malaria. XXVIII. The development of resistance to mefloquine (WR 142,490). Annals of Tropical Medicine and Parasitology, 69, 155-171.
18. Peters, W., Robinson, B. L. & Ellis, D. S. (1987). The chemotherapy of rodent malaria. XLII. Halofantrine and halofantrine resistance. Annals of Tropical Medicine and Parasitology, 81, 639-646.
19. Peters, W., Robinson, B. L., Tovey, G., Rossier, J.C. & Jefford, C. J. (1993). The chemotherapy of rodent malaria. L. The activities of some synthetic 1,2,4-trioxanes against chloroquine-sensitive and chloroquine resistant parasites. Part 3: Observations on 'Fenozan-50F', a difluorinated 3,3′-spirocyclopentane 1,2,4-trioxane. Annals of Tropical Medicine and Parasitology, 87, 111-123.
20. Posner, G. H. (1998). Antimalarial peroxides in the qinghaosu (artemisinin) and yingzhaosu families. Expert Opinion on Therapeutic Patents, 8, 1487-1494.
21. Price, R. N., Nosten, F., Luxemburger, C., Kham, A., Brockman, A., Chongsuphajaisiddhi, T. & White, N. J. (1996). Effects of artemisinin derivatives on malaria transmissibility. Lancet, i, 1654-1658.
22. Walker, D. J., Pitch, J. L., Peng, M. M., Robinson, B. L., Peters, W., Bhisutthibhan, J. & Meshnick, S. R. (1999). Mechanisms of artemisinin resistance in Plasmodium yoelii. Antimicrobial Agents and Chemotherapy, 43, in press.
23. White, N. J. (1997). Assessment of the pharmacodynamic properties of antimalarial drugs in vivo. Antimicrobial Agents and Chemotherapy, 41, 1413-1422.