Mutations of Arg440 and Gly455/Gly456 oppositely change pH sensing of Na+/H+ exchanger 1

Journal of Biological Chemistry

Volumn 278, Issue 14, 2003, Pages 11828-11835

  Wakabayashi, Shigeo ^a   Hisamitsu, Takashi ^b   Pang, Tianxiang ^b   Shigekawa, Munekazu ^b  

^a NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

PERTURBATION TECHNIQUES; PH EFFECTS; SODIUM COMPOUNDS;

ALKALINIZATION;

BIOCHEMISTRY;

5 (N ETHYL N ISOPROPYL)AMILORIDE; ARGININE; GLYCINE; SODIUM PROTON EXCHANGE PROTEIN; SODIUM PROTON EXCHANGE PROTEIN 1; UNCLASSIFIED DRUG; AMILORIDE; DRUG DERIVATIVE; GROWTH FACTOR ACTIVATABLE NA H EXCHANGER NHE 1; GROWTH FACTOR-ACTIVATABLE NA-H EXCHANGER NHE-1; NEUROPROTECTIVE AGENT; PROTON; SODIUM;

ACIDITY; ALKALINITY; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; CELL PH; CONTROLLED STUDY; ENZYME SUBSTRATE; HUMAN; MUTATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; PROTON TRANSPORT; RAT; SENSOR; SODIUM TRANSPORT; CELL LINE; CHEMISTRY; DRUG EFFECT; EXTRACELLULAR SPACE; GENETICS; METABOLISM; MOLECULAR GENETICS; MUTAGENESIS; PH; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE; SEQUENCE HOMOLOGY; TRANSPORT AT THE CELLULAR LEVEL;

AMILORIDE; ARGININE; BIOLOGICAL TRANSPORT; CELL LINE; EXTRACELLULAR SPACE; GLYCINE; HUMANS; HYDROGEN-ION CONCENTRATION; MOLECULAR SEQUENCE DATA; MUTAGENESIS; NEUROPROTECTIVE AGENTS; PROTEIN STRUCTURE, TERTIARY; PROTONS; SEQUENCE HOMOLOGY, AMINO ACID; SODIUM; SODIUM-HYDROGEN ANTIPORTER;

EID: 0038823575     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M213243200     Document Type: Article

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