Angiotensin II inhibits the electrogenic Na+/HCO3- cotransport of cat cardiac myocytes

Journal of Molecular and Cellular Cardiology

Volumn 49, Issue 5, 2010, Pages 812-818

  De Giusti, Verónica C ^a   Orlowski, Alejandro ^a   Aiello, Ernesto A ^a  

^a FACULTAD DE CIENCIAS MÉDICAS   (Argentina)

Author keywords

Angiotensin II; Cardiac myocytes; ERK 1 2 kinase; Na+ HCO3 co transporter; P38 kinase

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 4 (4 FLUOROPHENYL) 2 (4 HYDROXYPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANGIOTENSIN II; BICARBONATE SODIUM COTRANSPORTER; CHELERYTHRINE; LOSARTAN; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; SODIUM PROTON EXCHANGE PROTEIN;

ALKALINIZATION; ANIMAL CELL; ARTICLE; CAT; CONTROLLED STUDY; ELECTRONEUROLOGY; EXTRACELLULAR POTASSIUM; EXTRACELLULAR SPACE; HEART MUSCLE CELL; NERVE CELL MEMBRANE STEADY POTENTIAL; NONHUMAN; PATCH CLAMP; PH; PRIORITY JOURNAL; REPOLARIZATION;

ACIDS; ACTION POTENTIALS; ANGIOTENSIN II; ANIMALS; CATS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HEART VENTRICLES; INTRACELLULAR SPACE; MODELS, BIOLOGICAL; MYOCYTES, CARDIAC; P38 MITOGEN-ACTIVATED PROTEIN KINASES; POTASSIUM; SODIUM-BICARBONATE SYMPORTERS; TIME FACTORS;

EID: 77957240695     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2010.07.018     Document Type: Article

References (67)

1. Karmazyn M., Moffat M.P. Role of Na+/H+ exchange in cardiac physiology and pathophysiology: mediation of myocardial reperfusion injury by the pH paradox. Cardiovasc Res 1993, 27:915-924.
2. Dart C., Vaughan-Jones R.D. Na(+)-HCO3- symport in the sheep cardiac Purkinje fibre. J Physiol 1992, 451:365-385.
3. Lagadic-Gossmann D., Buckler K.J., Vaughan-Jones R.D. Role of bicarbonate in pH recovery from intracellular acidosis in the guinea-pig ventricular myocyte. J Physiol 1992, 458:361-384.
4. Vaughan-Jones R.D., Villafuerte F.C., Swietach P., Yamamoto T., Rossini A., Spitzer K.W. pH-Regulated Na(+) influx into the mammalian ventricular myocyte: the relative role of Na(+)-H(+) exchange and Na(+)-HCO co-transport. J Cardiovasc Electrophysiol 2006, 17:S134-S140.
5. Vaughan-Jones R.D., Spitzer K.W., Swietach P. Intracellular pH regulation in heart. J Mol Cell Cardiol 2009, 46:318-331.
6. Camilion de Hurtado M.C., Perez N.G., Cingolani H.E. An electrogenic sodium-bicarbonate cotransport in the regulation of myocardial intracellular pH. J Mol Cell Cardiol 1995, 27:231-242.
7. Le Prigent K., Lagadic-Gossmann D., Mongodin E., Feuvray D. HCO3(-)-dependent alkalinizing transporter in adult rat ventricular myocytes: characterization and modulation. Am J Physiol 1997, 273:H2596-H2603.
8. Camilion de Hurtado M.C., Alvarez B.V., Perez N.G., Cingolani H.E. Role of an electrogenic Na(+)-HCO3- cotransport in determining myocardial pHi after an increase in heart rate. Circ Res 1996, 79:698-704.
9. Aiello E.A., Petroff M.G., Mattiazzi A.R., Cingolani H.E. Evidence for an electrogenic Na+-HCO3- symport in rat cardiac myocytes. J Physiol 1998, 512:137-148.
10. Yamamoto T., Swietach P., Rossini A., Loh S.H., Vaughan-Jones R.D., Spitzer K.W. Functional diversity of electrogenic Na+-HCO3- cotransport in ventricular myocytes from rat, rabbit and guinea pig. J Physiol 2005, 562:455-475.
11. Villa-Abrille M.C., Petroff M.G., Aiello E.A. The electrogenic Na+/HCO3- cotransport modulates resting membrane potential and action potential duration in cat ventricular myocytes. J Physiol 2007, 578:819-829.
12. Cordat E., Casey J.R. Bicarbonate transport in cell physiology and disease. Biochem J 2009, 417:423-439.
13. Fliegel L., Karmazyn M. The cardiac Na-H exchanger: a key downstream mediator for the cellular hypertrophic effects of paracrine, autocrine and hormonal factors. Biochem Cell Biol=Biochim Biolog Cell 2004, 82:626-635.
14. Cingolani H.E., Perez N.G., Aiello E.A., de Hurtado M.C. Intracellular signaling following myocardial stretch: an autocrine/paracrine loop. Reg Pep 2005, 128:211-220.
15. Ennis I.L., Cingolani H.E., Garciarena Camilión de Hurtado MC, Villa-Abrille MC, Aiello EA, et al.C.D. From Anrep's Phenomenon to myocardial hypertrophy: role of the Na+/H+ exchanger. Current. Cardiol Rev 2007, 3:149-164.
16. Kohout T.A., Rogers T.B. Angiotensin II activates the Na+/HCO3- symport through a phosphoinositide-independent mechanism in cardiac cells. J Biol Chem 1995, 270:20432-20438.
17. Robey R.B., Ruiz O.S., Espiritu D.J., Ibanez V.C., Kear F.T., Noboa O.A., et al. Angiotensin II stimulation of renal epithelial cell Na/HCO3 cotransport activity: a central role for Src family kinase/classic MAPK pathway coupling. J Mem Biol 2002, 187:135-145.
18. Baetz D., Haworth R.S., Avkiran M., Feuvray D. The ERK pathway regulates Na(+)-HCO(3)(-) cotransport activity in adult rat cardiomyocytes. Am J Physiol 2002, 283:H2102-H2109.
19. De Giusti V.C., Garciarena C.D., Aiello E.A. Role of reactive oxygen species (ROS) in angiotensin II-induced stimulation of the cardiac Na+/HCO3- cotransport. J Mol Cell Cardiol 2009, 47:716-722.
20. Aiello E.A., Cingolani H.E. Angiotensin II stimulates cardiac L-type Ca(2+) current by a Ca(2+)- and protein kinase C-dependent mechanism. Am J Physiol 2001, 280:H1528-H1536.
21. De Giusti V.C., Correa M.V., Villa-Abrille M.C., Beltrano C., Yeves A.M., de Cingolani G.E., et al. The positive inotropic effect of endothelin-1 is mediated by mitochondrial reactive oxygen species. Life Sci 2008, 83:264-271.
22. Perez N.G., Alvarez B.V. Camilion de Hurtado MC, Cingolani HE. pHi regulation in myocardium of the spontaneously hypertensive rat. Compensated enhanced activity of the Na(+)-H+ exchanger. Circ Res 1995, 77:1192-1200.
23. Hoshino K., Avkiran M. Effects of moderate hypothermia on sarcolemmal Na(+)/H(+) exchanger activity and its inhibition by cariporide in cardiac ventricular myocytes. Brit J Pharmacol 2001, 134:1587-1595.
24. van Borren M.M., Baartscheer A., Wilders R., Ravesloot J.H. NHE-1 and NBC during pseudo-ischemia/reperfusion in rabbit ventricular myocytes. J Mol Cell Cardiol 2004, 37:567-577.
25. Roos A. Boron WF. Intracellular pH. Physiol Rev 1981, 61:296-434.
26. Leem C.H., Lagadic-Gossmann D., Vaughan-Jones R.D. Characterization of intracellular pH regulation in the guinea-pig ventricular myocyte. J Physiol 1999, 517:159-180.
27. Ch'en F.F., Villafuerte F.C., Swietach P., Cobden P.M., Vaughan-Jones R.D. S0859, an N-cyanosulphonamide inhibitor of sodium-bicarbonate cotransport in the heart. Brit J Pharmacol 2008, 153:972-982.
28. Kyriakis J.M., Avruch J. Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation. Physiol Rev 2001, 81:807-869.
29. Fischer R., Dechend R., Gapelyuk A., Shagdarsuren E., Gruner K., Gruner A., et al. Angiotensin II-induced sudden arrhythmic death and electrical remodeling. Am J Physiol 2007, 293:H1242-H1253.
30. Goette A., Lendeckel U. Electrophysiological effects of angiotensin II. Part I: signal transduction and basic electrophysiological mechanisms. Europace 2008, 10:238-241.
31. Petroff M.G., Aiello E.A., Palomeque J., Salas M.A., Mattiazzi A. Subcellular mechanisms of the positive inotropic effect of angiotensin II in cat myocardium. J Physiol 2000, 529:189-203.
32. Chorvatova A., Gallo-Payet N., Casanova C., Payet M.D. Modulation of membrane potential and ionic currents by the AT1 and AT2 receptors of angiotensin II. Cell Signall 1996, 8:525-532.
33. Morita H., Kimura J., Endoh M. Angiotensin II activation of a chloride current in rabbit cardiac myocytes. J Physiol 1995, 483:119-130.
34. Sonoyama K., Ninomiya H., Igawa O., Kaetsu Y., Furuse Y., Hamada T., et al. Inhibition of inward rectifier K+ currents by angiotensin II in rat atrial myocytes: lack of effects in cells from spontaneously hypertensive rats. Hypertens Res 2006, 29:923-934.
35. Domenighetti A.A., Boixel C., Cefai D., Abriel H., Pedrazzini T. Chronic angiotensin II stimulation in the heart produces an acquired long QT syndrome associated with IK1 potassium current downregulation. J Mol Cell Cardiol 2007, 42:63-70.
36. Caballero R., Gomez R., Moreno I., Nunez L., Gonzalez T., Arias C., et al. Interaction of angiotensin II with the angiotensin type 2 receptor inhibits the cardiac transient outward potassium current. Cardiovasc Res 2004, 62:86-95.
37. Khandoudi N., Albadine J., Robert P., Krief S., Berrebi-Bertrand I., Martin X., et al. Inhibition of the cardiac electrogenic sodium bicarbonate cotransporter reduces ischemic injury. Cardiovas Res 2001, 52:387-396.
38. Damkier H.H., Nielsen S., Praetorius J. An anti-NH2-terminal antibody localizes NBCn1 to heart endothelia and skeletal and vascular smooth muscle cells. Am J Physiol 2006, 290:H172-H180.
39. Boedtkjer E., Praetorius J., Fuchtbauer E.M., Aalkjaer C. Antibody-independent localization of the electroneutral Na+-HCO3- cotransporter NBCn1 (slc4a7) in mice. Am J Physiol 2008, 294:C591-C603.
40. Loiselle F.B., Jaschke P., Casey J.R. Structural and functional characterization of the human NBC3 sodium/bicarbonate co-transporter carboxyl-terminal cytoplasmic domain. Mol Mem Biol 2003 Oct-Dec, 20(4):307-317.
41. Haworth R.S., Dashnyam S., Avkiran M. Ras triggers acidosis-induced activation of the extracellular-signal-regulated kinase pathway in cardiac myocytes. Biochem J 2006, 399:493-501.
42. Li Y., Yamada H., Kita Y., Kunimi M., Horita S., Suzuki M., et al. Roles of ERK and cPLA2 in the angiotensin II-mediated biphasic regulation of Na+-HCO3(-) transport. J Am Soc Nephrol 2008, 19:252-259.
43. Upmacis R.K., Deeb R.S., Resnick M.J., Lindenbaum R., Gamss C., Mittar D., et al. Involvement of the mitogen-activated protein kinase cascade in peroxynitrite-mediated arachidonic acid release in vascular smooth muscle cells. Am J Physiol 2004, 286:C1271-C1280.
44. Husain S., Abdel-Latif A.A. Endothelin-1 activates p38 mitogen-activated protein kinase and cytosolic phospholipase A2 in cat iris sphincter smooth muscle cells. Biochem J 1999, 342:87-96.
45. Kalyankrishna S., Malik K.U. Norepinephrine-induced stimulation of p38 mitogen-activated protein kinase is mediated by arachidonic acid metabolites generated by activation of cytosolic phospholipase A(2) in vascular smooth muscle cells. J Pharmacol Exp Ther 2003, 304:761-772.
46. Nito C., Kamada H., Endo H., Niizuma K., Myer D.J., Chan P.H. Role of the p38 mitogen-activated protein kinase/cytosolic phospholipase A2 signaling pathway in blood-brain barrier disruption after focal cerebral ischemia and reperfusion. J Cereb Blood Flow Metab 2008, 28:1686-1696.
47. Wenzel S., Taimor G., Piper H.M., Schluter K.D. Redox-sensitive intermediates mediate angiotensin II-induced p38 MAP kinase activation, AP-1 binding activity, and TGF-beta expression in adult ventricular cardiomyocytes. FASEB J 2001, 15:2291-2293.
48. Kimura S., Zhang G.X., Nishiyama A., Shokoji T., Yao L., Fan Y.Y., et al. Role of NAD(P)H oxidase- and mitochondria-derived reactive oxygen species in cardioprotection of ischemic reperfusion injury by angiotensin II. Hypertension 2005, 45:860-866.
49. Bendall J.K., Cave A.C., Heymes C., Gall N., Shah A.M. Pivotal role of a gp91(phox)-containing NADPH oxidase in angiotensin II-induced cardiac hypertrophy in mice. Circulation 2002, 105:293-296.
50. Izumiya Y., Kim S., Izumi Y., Yoshida K., Yoshiyama M., Matsuzawa A., et al. Apoptosis signal-regulating kinase 1 plays a pivotal role in angiotensin II-induced cardiac hypertrophy and remodeling. Circ Res 2003, 93:874-883.
51. Palomeque J., Sapia L., Hajjar R.J., Mattiazzi A. Vila Petroff M. Angiotensin II-induced negative inotropy in rat ventricular myocytes: role of reactive oxygen species and p38 MAPK. Am J Physiol 2006, 290:H96-H106.
52. Spallarossa P., Altieri P., Garibaldi S., Ghigliotti G., Barisione C., Manca V., et al. Matrix metalloproteinase-2 and -9 are induced differently by doxorubicin in H9c2 cells: the role of MAP kinases and NAD(P)H oxidase. Cardiovasc Res 2006, 69:736-745.
53. Sabri A., Lucchesi P.A. ANG II and cardiac myocyte contractility: p38 is not stressed out!. Am J Physiol 2006, 290:H72-H73.
54. Salas M.A., Vila-Petroff M.G., Palomeque J., Aiello E.A., Mattiazzi A. Positive inotropic and negative lusitropic effect of angiotensin II: intracellular mechanisms and second messengers. J Mol Cell Cardiol 2001, 33:1957-1971.
55. Rivard K., Paradis P., Nemer M., Fiset C. Cardiac-specific overexpression of the human type 1 angiotensin II receptor causes delayed repolarization. Cardiovasc Res 2008, 78:53-62.
56. Zhou C., Ziegler C., Birder L.A., Stewart A.F., Levitan E.S. and stretch activate NADPH oxidase to destabilize cardiac Kv4.3 channel mRNA. Circ Res 2006, 98:1040-1047.
57. Wang Y.H., Shi C.X., Dong F., Sheng J.W., Xu Y.F. Inhibition of the rapid component of the delayed rectifier potassium current in ventricular myocytes by angiotensin II via the AT1 receptor. Brit J Pharmacol 2008, 154:429-439.
58. Ichiyanagi O., Ishii K., Endoh M. Angiotensin II increases L-type Ca2+ current in gramicidin D-perforated adult rabbit ventricular myocytes: comparison with conventional patch-clamp method. Pflugers Arch 2002, 444:107-116.
59. Sandmann S., Yu M., Kaschina E., Blume A., Bouzinova E., Aalkjaer C., et al. Differential effects of angiotensin AT1 and AT2 receptors on the expression, translation and function of the Na+-H+ exchanger and Na+-HCO3- symporter in the rat heart after myocardial infarction. J Am Coll Cardiol 2001, 37:2154-2165.
60. Schafer C., Ladilov Y.V., Siegmund B., Piper H.M. Importance of bicarbonate transport for protection of cardiomyocytes against reoxygenation injury. Am J Physiol 2000, 278:H1457-H1463.
61. Vandenberg J.I., Metcalfe J.C., Grace A.A. Mechanisms of pHi recovery after global ischemia in the perfused heart. Circ Res 1993, 72:993-1003.
62. Doggrell S.A., Hancox J.C. Is timing everything? Therapeutic potential of modulators of cardiac Na(+) transporters. Exp Op Invest Drugs 2003, 12:1123-1142.
63. Baartscheer A., van Borren M.M. Sodium ion transporters as new therapeutic targets in heart failure. Cardiovas Hematol Agents Med Chem 2008, 6:229-236.
64. De Mello W.C., Danser A.H. Angiotensin II and the heart: on the intracrine renin-angiotensin system. Hypertension 2000, 35:1183-1188.
65. Palomeque J., Delbridge L., Petroff M.V. Angiotensin II: a regulator of cardiomyocyte function and survival. Front Biosci 2009, 14:5118-5133.
66. Yamamoto T., Shirayama T., Sakatani T., Takahashi T., Tanaka H., Takamatsu T., et al. Enhanced activity of ventricular Na+-HCO3- cotransport in pressure overload hypertrophy. Am J Physiol 2007, 293:H1254-H1264.
67. Lebeche D., Kaprielian R., Hajjar R. Modulation of action potential duration on myocyte hypertrophic pathways. J Mol Cell Cardiol 2006, 40:725-735.