Characterization of sabiporide, a new specific NHE-1 inhibitor exhibiting slow dissociation kinetics and cardioprotective effects

European Journal of Pharmacology

Volumn 459, Issue 2-3, 2003, Pages 151-158

  Touret, Nicolas ^a   Tanneur, Valérie ^a   Godart, Hélène ^a   Seidler, Randolph ^b   Taki, Naoyuki ^b   Bürger, Erich ^b   Dämmgen, Jürgen ^b   Counillon, Laurent ^a  

^a UNIVERSITÉ CÔTE D'AZUR   (France)

^b BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

Author keywords

Cardioprotective effect; Sabiporide; Slow dissociation kinetics

Indexed keywords

AMILORIDE; CARIPORIDE; GUANIDINE DERIVATIVE; ISOPROTEIN; PROTEIN INHIBITOR; SABIPORIDE; SODIUM PROTON EXCHANGE PROTEIN; SODIUM PROTON EXCHANGE PROTEIN 1; SODIUM PROTON EXCHANGE PROTEIN 2; SODIUM PROTON EXCHANGE PROTEIN 3; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING KINETICS; CONTROLLED STUDY; DISSOCIATION; DRUG EFFECT; FEMALE; FIBROBLAST; HEART MUSCLE CELL; HEART PROTECTION; HUMAN; HUMAN CELL; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; THROMBOCYTE;

EID: 0037449475     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(02)02824-8     Document Type: Article

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