Amiloride docking to acid-sensing ion channel-1

Journal of Biological Chemistry

Volumn 285, Issue 13, 2010, Pages 9627-9635

  Qadri, Yawar J ^a   Song, Yuhua ^b   Fuller, Catherine M ^a   Benos, Dale J ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b and Radiation Oncology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACID-SENSING ION CHANNELS; AMILORIDE; ANTIPORTERS; DOCKING SITES; EPITHELIAL SODIUM CHANNELS; EXPERIMENTAL DATA; EXPERIMENTAL TECHNIQUES; INTERACTION SITE; MOLECULAR DOCKING; PATCH CLAMP; SMALL MOLECULES; SODIUM TRANSPORT; SPURIOUS INTERACTIONS; STRUCTURAL BASIS; VIRTUAL SCREENING; VOLTAGE SENSITIVITY;

ACIDS; APPLICATION SPECIFIC INTEGRATED CIRCUITS; DIGITAL LIBRARIES; DOCKING; IONS; MODEL STRUCTURES; PROTEINS;

DRUG INTERACTIONS;

3',4' DICHLOROBENZAMIL; 5 (N,N HEXAMETHYLENE)AMILORIDE; ACID SENSING ION CHANNEL; ACID SENSING ION CHANNEL 1; AMILORIDE; BENZAMIDINE; BENZAMIL; DIMETHYL SULFOXIDE; UNCLASSIFIED DRUG; ASIC CHANNEL; NERVE PROTEIN; SODIUM CHANNEL; SODIUM CHANNEL BLOCKING AGENT;

ANIMAL CELL; ARTICLE; BINDING SITE; DRUG ACTIVITY; DRUG PROTEIN BINDING; ELECTRIC POTENTIAL; MOLECULAR DOCKING; NONHUMAN; NUCLEOTIDE SEQUENCE; PATCH CLAMP; PRIORITY JOURNAL; PROTEIN STRUCTURE; AMINO ACID SEQUENCE; ANIMAL; CHEMISTRY; CHICKEN; CHO CELL; CRICETULUS; HAMSTER; HUMAN; IC 50; METABOLISM; MOLECULAR GENETICS; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE; SEQUENCE HOMOLOGY;

AMILORIDE; AMINO ACID SEQUENCE; ANIMALS; CHICKENS; CHO CELLS; CRICETINAE; CRICETULUS; HUMANS; INHIBITORY CONCENTRATION 50; MOLECULAR SEQUENCE DATA; NERVE TISSUE PROTEINS; PATCH-CLAMP TECHNIQUES; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; SEQUENCE HOMOLOGY, AMINO ACID; SODIUM CHANNEL BLOCKERS; SODIUM CHANNELS;

EID: 77951223851     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.082735     Document Type: Article

References (51)

1. Kellenberger, S., and Schild, L. (2002) Physiol. Rev. 82, 735-767
2. Bicking, J. B., Mason, J. W., Woltersdorf, O. W., Jones, J. H., Kwong, S. F., Robb, C. M., and Cragoe, E. J. (1965) J. Med. Chem. 8, 638-642
3. Benos, D. J. (1982) Am. J. Physiol. 242, C131-C145
4. Benos, D. J., and Stanton, B. A. (1999) J. Physiol. 520, 631-644
5. Adams, C. M., Snyder, P. M., and Welsh, M. J. (1999) J. Biol. Chem. 274, 15500-15504
6. Li, X. J., Xu, R. H., Guggino, W. B., and Snyder, S. H. (1995) Mol. Pharmacol. 47, 1133-1140
7. Kieber-Emmons, T., Lin, C., Foster, M. H., and Kleyman, T. R. (1999) J. Biol. Chem. 274, 9648-9655
8. Ismailov, II, Kieber-Emmons, T., Lin, C., Berdiev, B. K., Shlyonsky, V. G., Patton, H. K., Fuller, C. M., Worrell, R., Zuckerman, J. B., Sun, W., Eaton, D. C., Benos, D. J., and Kleyman, T. R. (1997) J. Biol. Chem. 272, 21075-21083
9. Kashlan, O. B., Sheng, S., and Kleyman, T. R. (2005) J. Biol. Chem. 280, 26206-26215
10. Teiwes, J., and Toto, R. D. (2007) Am. J. Hypertens. 20, 109-117
11. Hirsh, A. J., Zhang, J., Zamurs, A., Fleegle, J., Thelin, W. R., Caldwell, R. A., Sabater, J. R., Abraham, W. M., Donowitz, M., Cha, B., Johnson, K. B., St George, J. A., Johnson, M. R., and Boucher, R. C. (2008) J. Pharmacol. Exp. Ther. 325, 77-88
12. Xiong, Z. G., Pignataro, G., Li, M., Chang, S. Y., and Simon, R. P. (2008) Curr. Opin. Pharmacol. 8, 25-32
13. Kapoor, N., Bartoszewski, R., Qadri, Y. J., Bebok, Z., Bubien, J. K., Fuller, C. M., and Benos, D. J. (2009) J. Biol. Chem. 284, 24526-24541
14. Bondarava, M., Li, T., Endl, E., and Wehner, F. (2009) Pflugers Arch. 458, 675-687
15. Ye, J. H., Gao, J., Wu, Y. N., Hu, Y. J., Zhang, C. P., and Xu, T. L. (2007) Biochem. Biophys. Res. Commun. 355, 986-992
16. Gonzales, E. B., Kawate, T., and Gouaux, E. (2009) Nature 460, 599-604
17. Jasti, J., Furukawa, H., Gonzales, E. B., and Gouaux, E. (2007) Nature 449, 316-323
18. Qadri, Y. J., Berdiev, B. K., Song, Y., Lippton, H. L., Fuller, C. M., and Benos, D. J. (2009) J. Biol. Chem. 284, 17625-17633
19. Pietra, F. (2009) J. Chem. Inf. Model 49, 972-977
20. Trott, O., and Olson, A. J. (2009) J. Comput. Chem. 30, 455-461
21. Eswar, N., John, B., Mirkovic, N., Fiser, A., Ilyin, V. A., Pieper, U., Stuart, A. C., Marti-Renom, M. A., Madhusudhan, M. S., Yerkovich, B., and Sali, A. (2003) Nucleic Acids Res. 31, 3375-3380
22. Kuduk, S. D., Di Marco, C. N., Chang, R. K., Dipardo, R. M., Cook, S. P., Cato, M. J., Jovanovska, A., Urban, M. O., Leitl, M., Spencer, R. H., Kane, S. A., Bilodeau, M. T., Hartman, G. D., and Bock, M. G. (2009) Bioorg. Med. Chem. Lett. 19, 2514-2518
23. Kelly, O., Lin, C., Ramkumar, M., Saxena, N. C., Kleyman, T. R., and Eaton, D. C. (2003) Am. J. Physiol. Renal Physiol. 285, F1279-F1290
24. Li, J., Sheng, S., Perry, C. J., and Kleyman, T. R. (2003) J. Biol. Chem. 278, 13867-13874
25. Schild, L., Schneeberger, E., Gautschi, I., and Firsov, D. (1997) J. Gen. Physiol. 109, 15-26
26. Ji, H. L., Bishop, L. R., Anderson, S. J., Fuller, C. M., and Benos, D. J. (2004) J. Biol. Chem. 279, 8428-8440
27. Larkin, M. A., Blackshields, G., Brown, N. P., Chenna, R., McGettigan, P. A., McWilliam, H., Valentin, F., Wallace, I. M., Wilm, A., Lopez, R., Thompson, J. D., Gibson, T. J., and Higgins, D. G. (2007) Bioinformatics 23, 2947-2948
28. Stothard, P. (2000) BioTechniques 28, 1102-1104
29. Shen, M. Y., and Sali, A. (2006) Protein Sci. 15, 2507-2524
30. Sali, A., and Blundell, T. L. (1993) J. Mol. Biol. 234, 779-815
31. Van Der Spoel, D., Lindahl, E., Hess, B., Groenhof, G., Mark, A. E., and Berendsen, H. J. (2005) J. Comput. Chem. 26, 1701-1718
32. Hess, B., Kutzner, C., van der Spoel, D., and Lindahl, E. (2008) J. Chem. Theory Comput. 4, 435-447
33. Schüttelkopf, A. W., and van Aalten, D. M. (2004) Acta Crystallogr. D Biol. Crystallogr. 60, 1355-1363
34. Heyer, L. J., Kruglyak, S., and Yooseph, S. (1999) Genome Res. 9, 1106-1115
35. Humphrey, W., Dalke, A., and Schulten, K. (1996) J. Mol. Graph 14, 33-38, 27-28
36. Team, R. D. C. (2008) R: A Language and Environment for Statistical Computing
37. Kleyman, T. R., and Cragoe, E. J., Jr. (1988) J. Membr. Biol. 105, 1-21
38. Jernigan, N. L., Paffett, M. L., Walker, B. R., and Resta, T. C. (2009) Am. J. Physiol. Lung Cell Mol. Physiol. 297, L271-L285
39. Garnovskaya, M. N., Mukhin, Y. V., Vlasova, T. M., and Raymond, J. R. (2003) J. Biol. Chem. 278, 16908-16915
40. Garnovskaya, M. N., Gettys, T. W., van Biesen, T., Prpic, V., Chuprun, J. K., and Raymond, J. R. (1997) J. Biol. Chem. 272, 7770-7776
41. Wang, W. Z., Chu, X. P., Li, M. H., Seeds, J., Simon, R. P., and Xiong, Z. G. (2006) J. Biol. Chem. 281, 29369-29378
42. Rotin, D., and Grinstein, S. (1989) Am. J. Physiol. 257, C1158-C1165
43. Palmer, L. G. (1985) J. Membr. Biol. 87, 191-199
44. Benos, D. J., Simon, S. A., Mandel, L. J., and Cala, P. M. (1976) J. Gen. Physiol. 68, 43-63
45. Palmer, L. G., and Andersen, O. S. (1989) Biophys. J. 55, 779-787
46. Segal, A., Awayda, M. S., Eggermont, J., Van Driessche, W., and Weber, W. M. (2002) Pflugers Arch. 443, 882-891
47. Reddy Ch, S., Vijayasarathy, K., Srinivas, E., Sastry, G. M., and Sastry, G. N. (2006) Comput. Biol. Chem. 30, 120-126
48. Stockand, J. D., Staruschenko, A., Pochynyuk, O., Booth, R. E., and Silverthorn, D. U. (2008) IUBMB Life 60, 620-628
49. Kleyman, T. R., Carattino, M. D., and Hughey, R. P. (2009) J. Biol. Chem. 284, 20447-20451
50. Hassell, A. M., An, G., Bledsoe, R. K., Bynum, J. M., Carter, H. L., 3rd, Deng, S. J., Gampe, R. T., Grisard, T. E., Madauss, K. P., Nolte, R. T., Rocque, W. J., Wang, L., Weaver, K. L., Williams, S. P., Wisely, G. B., Xu, R., and Shewchuk, L. M. (2007) Acta Crystallogr. D Biol. Crystallogr. 63, 72-79
51. Tannous, B. A., Christensen, A. P., Pike, L., Wurdinger, T., Perry, K. F., Saydam, O., Jacobs, A. H., García-Añoveros, J., Weissleder, R., Sena-Esteves, M., Corey, D. P., and Breakefield, X. O. (2009) Mol. Ther. 17, 810-819