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Volumn 20, Issue 6, 2007, Pages 735-750

The Na + /H + exchanger, NHE1, differentially regulates mitogen-activated protein kinase subfamilies after osmotic shrinkage in Ehrlich Lettre Ascites cells

Author keywords

Cell volume regulation; ERK; JNK; MEK1 2; Osmotic stress; P38 MAPK

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CARIPORIDE; CASPASE 3; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; SODIUM ION; SODIUM PROTON EXCHANGE PROTEIN 1; STRESS ACTIVATED PROTEIN KINASE;

EID: 35848941951     PISSN: 10158987     EISSN: None     Source Type: Journal    
DOI: 10.1159/000110434     Document Type: Article
Times cited : (39)

References (54)
  • 2
    • 33744827683 scopus 로고    scopus 로고
    • Osmotic stress and the cytoskeleton: The R(h)ole of Rho GTPases
    • Oxf
    • Ciano-Oliveira C, Thirone AC, Szaszi K, Kapus A: Osmotic stress and the cytoskeleton: the R(h)ole of Rho GTPases. Acta Physiol (Oxf) 2006;187:257-272.
    • (2006) Acta Physiol , vol.187 , pp. 257-272
    • Ciano-Oliveira, C.1    Thirone, A.C.2    Szaszi, K.3    Kapus, A.4
  • 3
    • 33750574131 scopus 로고    scopus 로고
    • Sensors and signal transduction pathways in vertebrate cell volume regulation
    • Hoffmann EK, Pedersen SF: Sensors and signal transduction pathways in vertebrate cell volume regulation. Contrib Nephrol 2006;152:54-104.
    • (2006) Contrib Nephrol , vol.152 , pp. 54-104
    • Hoffmann, E.K.1    Pedersen, S.F.2
  • 4
    • 11944262115 scopus 로고    scopus 로고
    • Heat shock protein 70 inhibits shrinkage-induced programmed cell death via mechanisms independent of effects on cell volume-regulatory membrane transport proteins
    • Nylandsted J, Jaattela M, Hoffmann EK, Pedersen SF: Heat shock protein 70 inhibits shrinkage-induced programmed cell death via mechanisms independent of effects on cell volume-regulatory membrane transport proteins. Pflugers Arch 2004;449:175-185.
    • (2004) Pflugers Arch , vol.449 , pp. 175-185
    • Nylandsted, J.1    Jaattela, M.2    Hoffmann, E.K.3    Pedersen, S.F.4
  • 6
    • 33646871233 scopus 로고    scopus 로고
    • + exchanger NHE1 in stress-induced signal transduction: Implications for cell proliferation and cell death
    • + exchanger NHE1 in stress-induced signal transduction: implications for cell proliferation and cell death. Pflugers Arch 2006;452:249-259.
    • (2006) Pflugers Arch , vol.452 , pp. 249-259
    • Pedersen, S.F.1
  • 7
  • 8
    • 0034652007 scopus 로고    scopus 로고
    • Apoptosis of leukemic cells accompanies reduction in intracellular pH after targeted inhibition of the Na+/H+ exchanger
    • Rich IN, Worthington-White D, Garden OA, Musk P: Apoptosis of leukemic cells accompanies reduction in intracellular pH after targeted inhibition of the Na+/H+ exchanger. Blood 2000;95:1427-1434.
    • (2000) Blood , vol.95 , pp. 1427-1434
    • Rich, I.N.1    Worthington-White, D.2    Garden, O.A.3    Musk, P.4
  • 9
    • 8644264053 scopus 로고    scopus 로고
    • MAP kinases and the adaptive response to hypertonicity: Functional preservation from yeast to mammals
    • Sheikh-Hamad D, Gustin MC: MAP kinases and the adaptive response to hypertonicity: functional preservation from yeast to mammals. Am J Physiol Renal Physiol 2004;287:F1102-F1110.
    • (2004) Am J Physiol Renal Physiol , vol.287
    • Sheikh-Hamad, D.1    Gustin, M.C.2
  • 10
    • 0031785280 scopus 로고    scopus 로고
    • Mannitol at clinical concentrations activates multiple signaling pathways and induces apoptosis in endothelial cells
    • Malek AM, Goss GG. Jiang L, Izumo S, Alper SL: Mannitol at clinical concentrations activates multiple signaling pathways and induces apoptosis in endothelial cells. Stroke 1998;29:2631-2640.
    • (1998) Stroke , vol.29 , pp. 2631-2640
    • Malek, A.M.1    Goss, G.G.2    Jiang, L.3    Izumo, S.4    Alper, S.L.5
  • 11
    • 0028880006 scopus 로고    scopus 로고
    • Xia Z, Dickens M, Raingeaud J, Davis RJ, Greenberg ME: Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science1995; 270:1326-1331.
    • Xia Z, Dickens M, Raingeaud J, Davis RJ, Greenberg ME: Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science1995; 270:1326-1331.
  • 12
    • 10044247350 scopus 로고    scopus 로고
    • c-Jun N-terminal protein kinase 1 (JNK1), but not JNK2, is essential for tumor necrosis factor alpha-induced c-Jun kinase activation and apoptosis
    • Liu J, Minemoto Y, Lin A: c-Jun N-terminal protein kinase 1 (JNK1), but not JNK2, is essential for tumor necrosis factor alpha-induced c-Jun kinase activation and apoptosis. Mol Cell Biol 2004;24:10844-10856.
    • (2004) Mol Cell Biol , vol.24 , pp. 10844-10856
    • Liu, J.1    Minemoto, Y.2    Lin, A.3
  • 13
    • 14844307612 scopus 로고    scopus 로고
    • HSP70 deficiency results in activation of c-Jun N-terminal Kinase, extracellular signal-regulated kinase, and caspase-3 in hyperosmolarity-induced apoptosis
    • Lee JS, Lee JJ, Seo JS: HSP70 deficiency results in activation of c-Jun N-terminal Kinase, extracellular signal-regulated kinase, and caspase-3 in hyperosmolarity-induced apoptosis. J Biol Chem 2005;280:6634-6641.
    • (2005) J Biol Chem , vol.280 , pp. 6634-6641
    • Lee, J.S.1    Lee, J.J.2    Seo, J.S.3
  • 16
    • 0035066383 scopus 로고    scopus 로고
    • Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation
    • Kyriakis, J. M. and Avruch, J. (2001). Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation. Physiol Rev. 81, 807-869.
    • (2001) Physiol Rev , vol.81 , pp. 807-869
    • Kyriakis, J.M.1    Avruch, J.2
  • 17
    • 16844366178 scopus 로고    scopus 로고
    • Uhlik MT, Abell AN, Cuevas BD, Nakamura K, Johnson GL: Wiring diagrams of MAPK regulation by MEKK1, 2, and 3. BiochemCell Biol 2004;82:658-663.
    • Uhlik MT, Abell AN, Cuevas BD, Nakamura K, Johnson GL: Wiring diagrams of MAPK regulation by MEKK1, 2, and 3. BiochemCell Biol 2004;82:658-663.
  • 18
    • 27644575157 scopus 로고    scopus 로고
    • Coordinating ERK/MAPK signalling through scaffolds and inhibitors
    • Kolch W: Coordinating ERK/MAPK signalling through scaffolds and inhibitors. Nat Rev Mol Cell Biol 2005;6:827-837.
    • (2005) Nat Rev Mol Cell Biol , vol.6 , pp. 827-837
    • Kolch, W.1
  • 19
    • 0035831516 scopus 로고    scopus 로고
    • Stress-induced inhibition of ERK1 and ERK2 by direct interaction with p38 MAP kinase
    • Zhang H, Shi X, Hampong M, Blanis L, Pelech S: Stress-induced inhibition of ERK1 and ERK2 by direct interaction with p38 MAP kinase. J Biol Chem 2001;276:6905-6908.
    • (2001) J Biol Chem , vol.276 , pp. 6905-6908
    • Zhang, H.1    Shi, X.2    Hampong, M.3    Blanis, L.4    Pelech, S.5
  • 21
    • 0036729475 scopus 로고    scopus 로고
    • Mechanisms of activation of NHE by cell shrinkage and by calyculin A in Ehrlich ascites tumor cells
    • Pedersen SF, Varming C, Christensen ST, Hoffmann EK: Mechanisms of activation of NHE by cell shrinkage and by calyculin A in Ehrlich ascites tumor cells. J Membr Biol 2002;189:67-81.
    • (2002) J Membr Biol , vol.189 , pp. 67-81
    • Pedersen, S.F.1    Varming, C.2    Christensen, S.T.3    Hoffmann, E.K.4
  • 23
    • 0345826111 scopus 로고    scopus 로고
    • ERK is regulated by sodiumproton exchanger in rat aortic vascular smooth muscle cells
    • Mukhin YV, Garnovskaya MN, Ullian ME, Raymond JR: ERK is regulated by sodiumproton exchanger in rat aortic vascular smooth muscle cells. J Biol Chem 2004;279:1845-1852.
    • (2004) J Biol Chem , vol.279 , pp. 1845-1852
    • Mukhin, Y.V.1    Garnovskaya, M.N.2    Ullian, M.E.3    Raymond, J.R.4
  • 26
    • 34249884235 scopus 로고    scopus 로고
    • + exchange in regulation of p38 mitogen-activated protein kinase activity and cell death after chemical anoxia in NIH3T3 fibroblasts
    • Arch
    • + exchange in regulation of p38 mitogen-activated protein kinase activity and cell death after chemical anoxia in NIH3T3 fibroblasts. Pflugers Arch 2007.
    • (2007) Pflugers
    • Rentsch, M.L.1    Ossum, C.G.2    Hoffmann, E.K.3    Pedersen, S.F.4
  • 27
    • 33646771019 scopus 로고    scopus 로고
    • + exchanger isoform 1 inhibition is mediated by reduced mitogen-activated protein kinase activation secondary to improved mitochondrial integrity and decreased generation of mitochondrial-derived reactive oxygen species. J Pharmacol Exp Ther 2006;317:1036-1043.
    • + exchanger isoform 1 inhibition is mediated by reduced mitogen-activated protein kinase activation secondary to improved mitochondrial integrity and decreased generation of mitochondrial-derived reactive oxygen species. J Pharmacol Exp Ther 2006;317:1036-1043.
  • 28
    • 85065005170 scopus 로고    scopus 로고
    • + exchanger, NHE1. Arch Biochem.Biophys 2006.
    • + exchanger, NHE1. Arch Biochem.Biophys 2006.
  • 29
    • 33646869421 scopus 로고    scopus 로고
    • Causal relationship between NHE1, NKCC1, MAPKs and ERM proteins after osmotic shrinkage in Ehrlich Lettre mouse ascites tumor cells
    • Darborg B, Hoffmann EK, Pedersen SF: Causal relationship between NHE1, NKCC1, MAPKs and ERM proteins after osmotic shrinkage in Ehrlich Lettre mouse ascites tumor cells. FASEB J 2005;19(5 Part 2 Suppl. S):A1155.
    • (2005) FASEB J , vol.19 , Issue.5 PART 2 SUPPL. S
    • Darborg, B.1    Hoffmann, E.K.2    Pedersen, S.F.3
  • 32
    • 0024203607 scopus 로고
    • pH regulation in single glomerular mesangial cells. I. Acid extrusion in absence and presence of HCO3-
    • Boyarsky G, Ganz MB, Sterzel RB, Boron WF: pH regulation in single glomerular mesangial cells. I. Acid extrusion in absence and presence of HCO3-. Am J Physiol 1988;255:C844-C856.
    • (1988) Am J Physiol , vol.255
    • Boyarsky, G.1    Ganz, M.B.2    Sterzel, R.B.3    Boron, W.F.4
  • 33
    • 0029670107 scopus 로고    scopus 로고
    • + exchanger in Ehrlich ascites tumor cells: Mechanisms involved in the activation and a role for the exchanger in cell volume regulation
    • + exchanger in Ehrlich ascites tumor cells: mechanisms involved in the activation and a role for the exchanger in cell volume regulation. J Membr Biol 1996;149:141-159.
    • (1996) J Membr Biol , vol.149 , pp. 141-159
    • Pedersen, S.F.1    Kramhoft, B.2    Jorgensen, N.K.3    Hoffmann, E.K.4
  • 35
    • 33749355316 scopus 로고    scopus 로고
    • Cholesterol modulates the volume regulated anion current in Ehrlich Lettre Ascites cells via effects on Rho and F-actin
    • submitted
    • Klausen TK, Hougaard C, Hoffmann EK, Pedersen SF: Cholesterol modulates the volume regulated anion current in Ehrlich Lettre Ascites cells via effects on Rho and F-actin. Am J Physiol Cell Physiol submitted 2006.
    • (2006) Am J Physiol Cell Physiol
    • Klausen, T.K.1    Hougaard, C.2    Hoffmann, E.K.3    Pedersen, S.F.4
  • 37
    • 0346101747 scopus 로고    scopus 로고
    • + -2Cl- cotransporter in the nervous system: Evidence for a scaffolding role of the kinase
    • + -2Cl- cotransporter in the nervous system: evidence for a scaffolding role of the kinase. J Biol Chem 2003;278:52848-52856.
    • (2003) J Biol Chem , vol.278 , pp. 52848-52856
    • Piechotta, K.1    Garbarini, N.2    England, R.3    Delpire, E.4
  • 38
    • 33750567553 scopus 로고    scopus 로고
    • Osmosensing and signaling in the regulation of liver function
    • Schliess F, Haussinger D: Osmosensing and signaling in the regulation of liver function. Contrib Nephrol 2006;152:198-209.
    • (2006) Contrib Nephrol , vol.152 , pp. 198-209
    • Schliess, F.1    Haussinger, D.2
  • 39
    • 0029823496 scopus 로고    scopus 로고
    • Absence of volume regulatory mechanisms contributes to the rapid activation of apoptosis in thymocytes
    • Bortner CD, Cidlowski JA: Absence of volume regulatory mechanisms contributes to the rapid activation of apoptosis in thymocytes. Am J Physiol 1996;271:C950-C961.
    • (1996) Am J Physiol , vol.271
    • Bortner, C.D.1    Cidlowski, J.A.2
  • 40
    • 0041355337 scopus 로고    scopus 로고
    • + exchanger NHE1 by sustained intracellular acidosis. Evidence for a novel mechanism mediated by the ERK pathway
    • + exchanger NHE1 by sustained intracellular acidosis. Evidence for a novel mechanism mediated by the ERK pathway. J Biol Chem 2003;278:31676-31684.
    • (2003) J Biol Chem , vol.278 , pp. 31676-31684
    • Haworth, R.S.1    McCann, C.2    Snabaitis, A.K.3    Roberts, N.A.4    Avkiran, M.5
  • 41
    • 0037164808 scopus 로고    scopus 로고
    • Cell migration requires both ion translocation and cytoskeletal anchoring by the Na-H exchanger NHE1
    • Denker SP, Barber DL: Cell migration requires both ion translocation and cytoskeletal anchoring by the Na-H exchanger NHE1. J Cell Biol 2002;159:1087-1096.
    • (2002) J Cell Biol , vol.159 , pp. 1087-1096
    • Denker, S.P.1    Barber, D.L.2
  • 43
    • 3042692979 scopus 로고    scopus 로고
    • + exchanger (NHE1) creates acidic microenvironments leading to hyaluronidase-2 and cathepsin B activation and breast tumor cell invasion
    • + exchanger (NHE1) creates acidic microenvironments leading to hyaluronidase-2 and cathepsin B activation and breast tumor cell invasion. J Biol Chem 2004;279:26991-27007.
    • (2004) J Biol Chem , vol.279 , pp. 26991-27007
    • Bourguignon, L.Y.1    Singleton, P.A.2    Diedrich, F.3    Stern, R.4    Gilad, E.5
  • 45
    • 0036083848 scopus 로고    scopus 로고
    • Osmotic stress activates Rac and Cdc42 in neutrophils: Role in hypertonicity-induced actin polymerization
    • Lewis A, Di Ciano C, Rotstein OD, Kapus A: Osmotic stress activates Rac and Cdc42 in neutrophils: role in hypertonicity-induced actin polymerization. Am.J Physiol Cell Physiol 2002;282:C271-C279.
    • (2002) Am.J Physiol Cell Physiol , vol.282
    • Lewis, A.1    Di Ciano, C.2    Rotstein, O.D.3    Kapus, A.4
  • 46
    • 0030911732 scopus 로고    scopus 로고
    • Activation of transcription factor NF-kappaB and p38 mitogen-activated protein kinase is mediated by distinct and separate stress effector pathways
    • Wesselborg S, Bauer MK, Vogt M, Schmitz ML, Schulze-Osthoff K: Activation of transcription factor NF-kappaB and p38 mitogen-activated protein kinase is mediated by distinct and separate stress effector pathways. J Biol Chem 1997;272:12422-12429.
    • (1997) J Biol Chem , vol.272 , pp. 12422-12429
    • Wesselborg, S.1    Bauer, M.K.2    Vogt, M.3    Schmitz, M.L.4    Schulze-Osthoff, K.5
  • 47
    • 0033570091 scopus 로고    scopus 로고
    • The mitogen-activated protein (MAP) kinase p38 and its upstream activator MAP kinase kinase 6 are involved in the activation of signal transducer and activator of transcription by hyperosmolarity
    • Bode JG, Gatsios P, Ludwig S, Rapp UR, Haussinger D, Heinrich PC, Graeve L: The mitogen-activated protein (MAP) kinase p38 and its upstream activator MAP kinase kinase 6 are involved in the activation of signal transducer and activator of transcription by hyperosmolarity. J Biol Chem 1999;274:30222-30227.
    • (1999) J Biol Chem , vol.274 , pp. 30222-30227
    • Bode, J.G.1    Gatsios, P.2    Ludwig, S.3    Rapp, U.R.4    Haussinger, D.5    Heinrich, P.C.6    Graeve, L.7
  • 48
    • 0030908882 scopus 로고    scopus 로고
    • Cytosolic alkalinization increases stress-activated protein kinase/c-Jun NH2-terminal kinase (SAPK/JNK) activity and p38 mitogen-activated protein kinase activity by a calcium-independent mechanism
    • Shrode LD, Rubie EA, Woodgett JR, Grinstein S: Cytosolic alkalinization increases stress-activated protein kinase/c-Jun NH2-terminal kinase (SAPK/JNK) activity and p38 mitogen-activated protein kinase activity by a calcium-independent mechanism. J Biol Chem 1997;272:13653-13659.
    • (1997) J Biol Chem , vol.272 , pp. 13653-13659
    • Shrode, L.D.1    Rubie, E.A.2    Woodgett, J.R.3    Grinstein, S.4
  • 51
    • 0141723393 scopus 로고    scopus 로고
    • Role of JNK in tumor development
    • Kennedy NJ, Davis RJ: Role of JNK in tumor development. Cell Cycle 2003;2:199-201.
    • (2003) Cell Cycle , vol.2 , pp. 199-201
    • Kennedy, N.J.1    Davis, R.J.2
  • 53
    • 0036098774 scopus 로고    scopus 로고
    • + -ATPase as a signal transducer
    • + -ATPase as a signal transducer. Eur J Biochem 2002;269:2434-2439.
    • (2002) Eur J Biochem , vol.269 , pp. 2434-2439
    • Xie, Z.1    Askari, A.2


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