Chronic metabolic acidosis upregulates rat kidney Na-HCO3- cotransporters NBCn1 and NBC3 but not NBC1

American Journal of Physiology - Renal Physiology

Volumn 282, Issue 2 51-2, 2002, Pages

  Kwon, Tae Hwan ^a,b   Fulton, Christiaan ^a   Wang, Weidong ^a   Kurtz, Ira ^c   Frøkiær, Jørgen ^a   Aalkjær, Christian ^a   Nielsen, Søren ^a  

^a AARHUS UNIVERSITY   (Denmark)

^b Dongguk University College of Medicine   (South Korea)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Acid base balance; Bicarbonate transport; Intercalated cell; Intracellular pH; Thick ascending limb

Indexed keywords

AMMONIA; BICARBONATE; CARRIER PROTEIN; PROTEIN NBC1; PROTEIN NBC3; PROTEIN NBCN1; UNCLASSIFIED DRUG;

ACID BASE BALANCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PH; CHRONIC DISEASE; CONTROLLED STUDY; CORRELATION ANALYSIS; HENLE LOOP; IMMUNOBLOTTING; IMMUNOCYTOCHEMISTRY; KIDNEY FUNCTION; MALE; METABOLIC ACIDOSIS; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN FUNCTION; RAT; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

EID: 0036083525     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00104.2001     Document Type: Article

References (47)

1. Chloride and bicarbonate transport in rat resistance arteries
2. Axial heterogeneity of sodium-bicarbonate cotransporter expression in the rabbit proximal tubule
3. Parallel adaptation of the rabbit renal cortical sodium/proton antiporter and sodium/bicarbonate cotransporter in metabolic acidosis and alkalosis
4. Cell mechanisms of proximal tubule acidification
5. Chronic metabolic acidosis increases NHE3 protein abundance in rat kidney
6. - cotransporter isoform NBC-3
7. Expression and distribution of renal vacuolar proton-translocating adenosine triphosphatase in response to chronic acid and alkali loads in the rat
8. - transport
9. Role of organic anions in renal response to dietary acid and base loads
10. - cotransporter
11. An electroneutral sodium/bicarbonate cotransporter NBCn1 and associated sodium channel
12. Proximal reabsorption during metabolic acidosis in the rat
13. - symport in the sheep cardiac Purkinje fibre
14. - cotransporter, BSC-1
15. + absorption by the thick ascending limb
16. + intake
17. Ammonia transport in the mammalian kidney
18. - cotransport in immortalized renal proximal tubule cells
19. Regulation of thick ascending limb ion transporter abundance in response to altered acid-base intake
20. Long-term regulation of renal Na-dependent cotransporters and ENaC: Response to altered acid-base intake
21. --cotransporter
22. 2 absorption
23. - co-transporter NBC 3 in rat kidney
24. Renal tubular sodium and water reabsorption in the isotonic sodium chloride-loaded rat
25. Response of intercalated cells of rat outer medullary collecting duct to chronic metabolic acidosis
26. Lithium-induced downregulation of aquaporin-2 water channel expression in rat kidney medulla
27. Immuno-electron microscopical localization of the electrogenic Na,HCO3 co-transporter (NBC) in rat kidney
28. Bicarbonate transport by rabbit cortical collecting tubules. Effect of acid and alkali loads in vivo on transport in vitro
29. Intracellular pH regulation in the rabbit cortical collecting duct A-type intercalated cell
30. Chronic metabolic acidosis causes an adaptation in the apical membrane Na/H antiporter and basolateral membrane Na(HCO3)3 symporter in the rat proximal convoluted tubule
31. Regulation of AQP6 mRNA and protein expression in rats in response to altered acid-base or water balance
32. Cloning, tissue distribution, genomic organization, and functional characterization of NBC3, a new member of the sodium bicarbonate cotransporter family
33. +-ATPase
34. - cotransporters: Cloning and physiology
35. - cotransporter from rat kidney
36. - cotransporter in mammalian and amphibian kidney
37. - cotransport in basolateral membrane vesicles isolated from rabbit renal cortex
38. + exchangers in health and disease processes
39. Mineralocorticoid modulation of rabbit medullary collecting duct acidification. A sodium-independent effect
40. Long-term regulation of four renal aquaporins in rats
41. +-ATPase in rabbit cortical collecting duct
42. - cotransporter in rat kidney
43. +-ATPase activity in salt-loaded rats by furosemide
44. Net acid transport by isolated perfused inner medullary collecting ducts
45. Apical proton secretion by the inner stripe of the outer medullary collecting duct
46. Aquaporin-6: An intracellular vesicle water channel protein in renal epithelia
47. i regulation in the outer medullary collecting duct