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Volumn 7, Issue 1, 2012, Pages 37-53

CD4 + T-cell subsets in rheumatoid arthritis

Author keywords

naive T cell; regulatory T cells; rheumatoid arthritis; Th1 Th2 Th17 subsets

Indexed keywords

ABATACEPT; CD28 ANTIGEN; CD57 ANTIGEN; METHOTREXATE;

EID: 84856677245     PISSN: 17584272     EISSN: 17584280     Source Type: Journal    
DOI: 10.2217/ijr.11.69     Document Type: Review
Times cited : (9)

References (227)
  • 2
    • 0032695262 scopus 로고    scopus 로고
    • Does partial control of inflammation prevent long-term joint damage? Clinical rationale for combination therapy with multiple disease-modifying antirheumatic drugs
    • Pincus T, Breedveld FC, Emery P. Does partial control of inflammation prevent long-term joint damage? Clinical rationale for combination therapy with multiple disease-modifying antirheumatic drugs. Clin. Exp. Rheumatol. 17(6), S2-S7 (1999). (Pubitemid 29503350)
    • (1999) Clinical and Experimental Rheumatology , vol.17 , Issue.6 SUPPL. 18
    • Pincus, T.1    Breedveld, F.C.2    Emery, P.3
  • 3
    • 77957196913 scopus 로고    scopus 로고
    • Rheumatoid arthritis
    • Scott DL, Wolfe F, Huizinga TW. Rheumatoid arthritis. Lancet 376(9746), 1094-1108 (2010).
    • (2010) Lancet , vol.376 , Issue.9746 , pp. 1094-1108
    • Scott, D.L.1    Wolfe, F.2    Huizinga, T.W.3
  • 4
    • 0027930325 scopus 로고
    • The molecular basis of susceptibility to rheumatoid arthritis
    • Winchester R. The molecular basis of susceptibility to rheumatoid arthritis. Adv. Immunol. 56, 389-466 (1994). (Pubitemid 24242228)
    • (1994) Advances in Immunology , vol.56 , pp. 389-466
    • Winchester, R.1
  • 5
    • 0023500817 scopus 로고
    • The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis
    • DOI 10.1002/art.1780301102
    • Gregersen PK, Silver J, Winchester RJ. The shared epitope hypothesis -an approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis. Arthrit. Rheumat. 30(11), 1205-1213 (1987). (Pubitemid 18005792)
    • (1987) Arthritis and Rheumatism , vol.30 , Issue.11 , pp. 1205-1213
    • Gregersen, P.K.1    Silver, J.2    Winchester, R.J.3
  • 6
    • 0025348745 scopus 로고
    • How important are T cells in chronic rheumatoid synovitis?
    • DOI 10.1002/art.1780330602
    • Firestein GS, Zvaifler NJ. How important are T cells in chronic rheumatoid synovitis? Arthrit. Rheumat. 33(6), 768-773 (1990). (Pubitemid 20205755)
    • (1990) Arthritis and Rheumatism , vol.33 , Issue.6 , pp. 768-773
    • Firestein, G.S.1    Zvaifler, N.J.2
  • 7
    • 0028907577 scopus 로고
    • The identification of germinal centers and follicular dendritic cell networks in rheumatoid synovial tissue Scand
    • Randen I, Mellbye OJ, Forre O, Natvig JB. The identification of germinal centers and follicular dendritic cell networks in rheumatoid synovial tissue Scand. J. Immunol. 41(5), 481-486 (1995).
    • (1995) J. Immunol. , vol.41 , Issue.5 , pp. 481-486
    • Randen, I.1    Mellbye, O.J.2    Forre, O.3    Natvig, J.B.4
  • 8
    • 0027373015 scopus 로고
    • Cellular immune mechanisms in rheumatoid arthritis and other inflammatory arthritides
    • DOI 10.1016/0952-7915(93)90106-3
    • Lanchbury JS, Pitzalis C. Cellular immune-mechanisms in rheumatoid arthritis and other inflammatory arthritides. Curr. Opin. Immunol. 5(6), 918-924 (1993). (Pubitemid 23347454)
    • (1993) Current Opinion in Immunology , vol.5 , Issue.6 , pp. 918-924
    • Lanchbury, J.S.1    Pitzalis, C.2
  • 9
    • 0026018164 scopus 로고
    • The immunopathogenesis of rheumatoid arthritis
    • Firestein GS, The immunopathogenesis of rheumatoid arthritis. Curr. Opin. Rheumatol. 3(3), 398-406 (1991).
    • (1991) Curr. Opin. Rheumatol. , vol.3 , Issue.3 , pp. 398-406
    • Firestein, G.S.1
  • 10
    • 0026752620 scopus 로고
    • The importance of the T-cell in initiating and maintaining the chronic synovitis of rheumatoid arthritis
    • Panayi GS, Lanchbury JS, Kingsley GH. The importance of the T-cell in initiating and maintaining the chronic synovitis of rheumatoid arthritis. Arthrit. Rheumat. 35(7), 729-735 (1992).
    • (1992) Arthrit. Rheumat. , vol.35 , Issue.7 , pp. 729-735
    • Panayi, G.S.1    Lanchbury, J.S.2    Kingsley, G.H.3
  • 11
    • 0036169592 scopus 로고    scopus 로고
    • How important are T cells in chronic rheumatoid synovitis? II. T cell-independent mechanisms from beginning to end
    • DOI 10.1002/art.502
    • Firestein GS, Zvaifler NJ. How important are T cells in chronic rheumatoid synovitis? II. T cell-independent mechanisms from beginning to end. Arthrit. Rheumat. 46(2), 298-308 (2002). (Pubitemid 34136567)
    • (2002) Arthritis and Rheumatism , vol.46 , Issue.2 , pp. 298-308
    • Firestein, G.S.1    Zvaifler, N.J.2
  • 12
    • 33746225592 scopus 로고    scopus 로고
    • Molecular and cellular basis of rheumatoid joint destruction
    • DOI 10.1016/j.imlet.2006.04.011, PII S0165247806001246
    • Karouzakis E, Neidhart M, Gay RE, Gay S. Molecular and cellular basis of rheumatoid joint destruction. Immunol. Lett. 106(1), 8-13 (2006). (Pubitemid 44093056)
    • (2006) Immunology Letters , vol.106 , Issue.1 , pp. 8-13
    • Karouzakis, E.1    Neidhart, M.2    Gay, R.E.3    Gay, S.4
  • 13
    • 0029039824 scopus 로고
    • The role of lymphocytes in rheumatoid arthritis
    • Salmon M, Gaston J. The role of lymphocytes in rheumatoid arthritis. Br. Med. Bull. 51, 332-345 (1995).
    • (1995) Br. Med. Bull. , vol.51 , pp. 332-345
    • Salmon, M.1    Gaston, J.2
  • 15
    • 0026713067 scopus 로고
    • Human cartilage proteoglycans as T cell autoantigens
    • Goodacre JA, Pearson JP. Human cartilage proteoglycans as T cell autoantigens. Ann. Rheum. Dis. 51(9), 1094-1097 (1992).
    • (1992) Ann. Rheum. Dis. , vol.51 , Issue.9 , pp. 1094-1097
    • Goodacre, J.A.1    Pearson, J.P.2
  • 16
    • 0029076258 scopus 로고
    • Human autoreactive T-cell clones show flexibility in recognizing overlapping microepitopes, but inflexibility in T-cell receptor usage, in T-cell receptor use in human autoimmune diseases
    • Londei M, Dayan C, Feldmann M, Acuto O, Quaratino S. Human autoreactive T-cell clones show flexibility in recognizing overlapping microepitopes, but inflexibility in T-cell receptor usage, in T-cell receptor use in human autoimmune diseases. Ann. NY Acad. Sci. 756, 345-348 (1995).
    • (1995) Ann. NY Acad. Sci. , vol.756 , pp. 345-348
    • Londei, M.1    Dayan, C.2    Feldmann, M.3    Acuto, O.4    Quaratino, S.5
  • 18
    • 0032417125 scopus 로고    scopus 로고
    • Functional subsets of CD4 T cells in rheumatoid synovitis
    • DOI 10.1002/1529-0131(199812)41:12<2108::AID-ART5>3.0.CO;2-Q
    • Namekawa T, Wagner UG, Goronzy JJ, Weyand CM. Functional subsets of CD4 T cells in rheumatoid synovitis. Arthrit. Rheumat. 41(12), 2108-2116 (1998). (Pubitemid 29009368)
    • (1998) Arthritis and Rheumatism , vol.41 , Issue.12 , pp. 2108-2116
    • Namekawa, T.1    Wagner, U.G.2    Goronzy, J.J.3    Weyand, C.M.4
  • 19
    • 0029876121 scopus 로고    scopus 로고
    • Role of cytokines in rheumatoid arthritis
    • DOI 10.1146/annurev.immunol.14.1.397
    • Feldmann M, Brennan FM, Maini RN. Role of cytokines in rheumatoid arthritis. Ann. Rev. Immunol. 14, 397-440 (1996). (Pubitemid 26130190)
    • (1996) Annual Review of Immunology , vol.14 , pp. 397-440
    • Feldmann, M.1    Brennan, F.M.2    Maini, R.N.3
  • 20
    • 65249103342 scopus 로고    scopus 로고
    • Quantitative heritability of anti-citrullinated protein antibody-positive and anti-citrullinated protein antibody-negative rheumatoid arthritis
    • van der Woude D, Houwing-Duistermaat JJ, Toes RE et al. Quantitative heritability of anti-citrullinated protein antibody-positive and anti-citrullinated protein antibody-negative rheumatoid arthritis. Arthrit. Rheumat. 60(4), 916-923 (2009).
    • (2009) Arthrit. Rheumat. , vol.60 , Issue.4 , pp. 916-923
    • Van Der Woude, D.1    Houwing-Duistermaat, J.J.2    Toes, R.E.3
  • 21
    • 0023500817 scopus 로고
    • The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis
    • DOI 10.1002/art.1780301102
    • Gregersen PK, Silver J, Winchester RJ. The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis. Arthrit. Rheumat. 30(11), 1205-1213 (1987). (Pubitemid 18005792)
    • (1987) Arthritis and Rheumatism , vol.30 , Issue.11 , pp. 1205-1213
    • Gregersen, P.K.1    Silver, J.2    Winchester, R.J.3
  • 23
    • 0033003164 scopus 로고    scopus 로고
    • The genetics revolution and the assault on rheumatoid arthritis
    • DOI 10.1002/1529-0131(199906)42:6<1071::AID-ANR1>3.0.CO;2-8
    • Seldin MF, Amos CI, Ward R, Gregersen PK. The genetics revolution and the assault on rheumatoid arthritis. Arthrit. Rheumat. 42(6), 1071-1079 (1999). (Pubitemid 29268942)
    • (1999) Arthritis and Rheumatism , vol.42 , Issue.6 , pp. 1071-1079
    • Seldin, M.F.1    Amos, C.I.2    Ward, R.3    Gregersen, P.K.4
  • 25
    • 78449255224 scopus 로고    scopus 로고
    • Susceptibility genes for rheumatoid arthritis -a rapidly expanding harvest
    • Gregersen PK. Susceptibility genes for rheumatoid arthritis -a rapidly expanding harvest. Bull. NYU Hosp. Joint Dis. 68(3), 179-182 (2010).
    • (2010) Bull. NYU Hosp. Joint Dis. , vol.68 , Issue.3 , pp. 179-182
    • Gregersen, P.K.1
  • 26
    • 78751705333 scopus 로고    scopus 로고
    • A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis
    • Padyukov L, Seielstad M, Ong RT et al. A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis. Ann. Rheumat. Dis. 70(2), 259-265 (2011).
    • (2011) Ann. Rheumat. Dis. , vol.70 , Issue.2 , pp. 259-265
    • Padyukov, L.1    Seielstad, M.2    Ong, R.T.3
  • 27
    • 79955004052 scopus 로고    scopus 로고
    • Genetics of rheumatoid arthritis: Time for a change?
    • de Vries R. Genetics of rheumatoid arthritis: time for a change? Curr. Opin. Rheumatol. 23, 227-232 (2011).
    • (2011) Curr. Opin. Rheumatol. , vol.23 , pp. 227-232
    • De Vries, R.1
  • 28
    • 70649086092 scopus 로고    scopus 로고
    • Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk
    • Raychaudhuri S, Thomson BP, Remmers EF et al. Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk. Nat. Genet. 41(12), 1313-1318 (2009).
    • (2009) Nat. Genet. , vol.41 , Issue.12 , pp. 1313-1318
    • Raychaudhuri, S.1    Thomson, B.P.2    Remmers, E.F.3
  • 29
    • 77249124540 scopus 로고    scopus 로고
    • Association of the CD28/CTLA4/ICOS polymorphisms with susceptibility to rheumatoid arthritis
    • Kim YO, Kim HJ, Kim SK, Chung JH, Hong SJ. Association of the CD28/CTLA4/ICOS polymorphisms with susceptibility to rheumatoid arthritis. Clin. Chem. Lab. Med. 48(3), 345-353 (2010).
    • (2010) Clin. Chem. Lab. Med. , vol.48 , Issue.3 , pp. 345-353
    • Kim, Y.O.1    Kim, H.J.2    Kim, S.K.3    Chung, J.H.4    Hong, S.J.5
  • 30
    • 77649158995 scopus 로고    scopus 로고
    • Evidence of epistasis between TNFRSF14 and TNFRSF6B polymorphisms in patients with rheumatoid arthritis
    • Perdigones N, Vigo AG, Lamas JR et al. Evidence of epistasis between TNFRSF14 and TNFRSF6B polymorphisms in patients with rheumatoid arthritis. Arthrit. Rheumat. 62(3), 705-710 (2010).
    • (2010) Arthrit. Rheumat. , vol.62 , Issue.3 , pp. 705-710
    • Perdigones, N.1    Vigo, A.G.2    Lamas, J.R.3
  • 31
    • 70450278797 scopus 로고    scopus 로고
    • Interleukin-12 gene polymorphisim in patients with giant cell arteritis, polymyalgia rheumatica and elderly-onset rheumatoid arthritis
    • Alvarez-Rodriguez L, Martinez-Taboada VM, Lopez-Hoyos M et al. Interleukin-12 gene polymorphisim in patients with giant cell arteritis, polymyalgia rheumatica and elderly-onset rheumatoid arthritis. Clin. Exp. Rheumatol. 27(1 Suppl. 52), S14-S18 (2009).
    • (2009) Clin. Exp. Rheumatol. , vol.27 , Issue.1 SUPPL. 52
    • Alvarez-Rodriguez, L.1    Martinez-Taboada, V.M.2    Lopez-Hoyos, M.3
  • 32
    • 21544443471 scopus 로고    scopus 로고
    • Interleukin 12 (IL12B) and interleukin 12 receptor (IL12RB1) gene polymorphisms in rheumatoid arthritis
    • Orozco G, Gonzalez-Gay MA, Paco L et al. Interleukin 12 (IL12B) and interleukin 12 receptor (IL12RB1) gene polymorphisms in rheumatoid arthritis. Hum. Immunol. 66(6), 710-715 (2005).
    • (2005) Hum. Immunol. , vol.66 , Issue.6 , pp. 710-715
    • Orozco, G.1    Gonzalez-Gay, M.A.2    Paco, L.3
  • 34
    • 51849120731 scopus 로고    scopus 로고
    • Association of the STAT4 gene with increased susceptibility for some immune-mediated diseases
    • Martinez A, Varade J, Marquez A et al. Association of the STAT4 gene with increased susceptibility for some immune-mediated diseases. Arthrit. Rheumat. 58(9), 2598-2602 (2008).
    • (2008) Arthrit. Rheumat. , vol.58 , Issue.9 , pp. 2598-2602
    • Martinez, A.1    Varade, J.2    Marquez, A.3
  • 35
    • 0036624721 scopus 로고    scopus 로고
    • Interleukin-7: From bench to clinic
    • DOI 10.1182/blood.V99.11.3892
    • Fry TJ, Mackall CL. Interleukin-7: from bench to clinic. Blood 99(11), 3892-3904 (2002). (Pubitemid 35332024)
    • (2002) Blood , vol.99 , Issue.11 , pp. 3892-3904
    • Fry, T.J.1    Mackall, C.L.2
  • 36
    • 0010991911 scopus 로고    scopus 로고
    • Long term (5 years) follow-up of rheumatoid arthritis patients treated with a depleting anti-CD4 monoclonal antibody, cM-T412
    • Moreland LW, Bucy RP, Jackson B, James T, Koopman WJ. Long term (5 years) follow-up of rheumatoid arthritis patients treated with a depleting anti-CD4 monoclonal antibody, cM-T412. Arthrit. Rheumat. 39(9), 1299-1299 (1996).
    • (1996) Arthrit. Rheumat. , vol.39 , Issue.9 , pp. 1299-1299
    • Moreland, L.W.1    Bucy, R.P.2    Jackson, B.3    James, T.4    Koopman, W.J.5
  • 38
    • 4243677368 scopus 로고    scopus 로고
    • Immune reconstitution in patients with severe rheumatoid arthritis (RA) recieving T-cell depleted and unmanipulated autologous haemopoietic stem cell grafts (HSCT)
    • Moore J, Biggs J, Milliken S et al. Immune reconstitution in patients with severe rheumatoid arthritis (RA) recieving T-cell depleted and unmanipulated autologous haemopoietic stem cell grafts (HSCT). Bone Marrow Trans. 27, S16-S17 (2001).
    • (2001) Bone Marrow Trans. , vol.27
    • Moore, J.1    Biggs, J.2    Milliken, S.3
  • 39
  • 40
    • 45149117515 scopus 로고    scopus 로고
    • Long-term follow-up of highly selected autologous stem cell transplantation in severe rheumatoid arthritis with studies of peripheral blood reconstitution and macroscopic and histological arthroscopic appearances
    • Abstract S290, 2000
    • Bingham S, Veale D, Fearon U et al. Long-term follow-up of highly selected autologous stem cell transplantation in severe rheumatoid arthritis with studies of peripheral blood reconstitution and macroscopic and histological arthroscopic appearances. Arthrit. Rheumat. 43(9), Abstract S290 (2000).
    • Arthrit. Rheumat. , vol.43 , Issue.9
    • Bingham, S.1    Veale, D.2    Fearon, U.3
  • 41
    • 33644958403 scopus 로고    scopus 로고
    • Telomeres, immune aging and autoimmunity
    • Goronzy JJ, Fujii H, Weyand CM. Telomeres, immune aging and autoimmunity. Exp. Gerontol. 41(3), 246-251 (2006).
    • (2006) Exp. Gerontol. , vol.41 , Issue.3 , pp. 246-251
    • Goronzy, J.J.1    Fujii, H.2    Weyand, C.M.3
  • 43
    • 84856675256 scopus 로고    scopus 로고
    • Premature aging in the immune system of patients with rheumatoid arthritis
    • Abstract S1994, 1998
    • Koetz K, Spickschen K, Goronzy JJ, Weyand CM. Premature aging in the immune system of patients with rheumatoid arthritis. Arthrit. Rheumat. 41(9) Abstract S1994 (1998).
    • Arthrit. Rheumat. , vol.41 , Issue.9
    • Koetz, K.1    Spickschen, K.2    Goronzy, J.J.3    Weyand, C.M.4
  • 44
    • 77953854915 scopus 로고    scopus 로고
    • Leukocyte function in the aging immune system
    • Desai A, Grolleau-Julius A, Yung R. Leukocyte function in the aging immune system. J. Leuk. Biol. 87(6), 1001-1009 (2010).
    • (2010) J. Leuk. Biol. , vol.87 , Issue.6 , pp. 1001-1009
    • Desai, A.1    Grolleau-Julius, A.2    Yung, R.3
  • 47
    • 13444268243 scopus 로고    scopus 로고
    • IL-7 deficiency and therapy-induced lymphopenia in rheumatoid arthritis
    • Ponchel F, Verburg R, Bingham S et al. IL-7 deficiency and therapy-induced lymphopenia in rheumatoid arthritis. Arthrit. Res. Ther. 7, 80-92 (2005).
    • (2005) Arthrit. Res. Ther. , vol.7 , pp. 80-92
    • Ponchel, F.1    Verburg, R.2    Bingham, S.3
  • 49
    • 0029670731 scopus 로고    scopus 로고
    • Oligoclonality of v ? 3 TCR chains in the CD8(+) T cell population of rheumatoid arthritis patients
    • Hingorani R, Monteiro J, Furie R et al. Oligoclonality of V ? 3 TCR chains in the CD8(+) T cell population of rheumatoid arthritis patients. J. Immunol. 156(2), 852-858 (1996).
    • (1996) J. Immunol. , vol.156 , Issue.2 , pp. 852-858
    • Hingorani, R.1    Monteiro, J.2    Furie, R.3
  • 51
    • 0029004199 scopus 로고
    • Mechanisms underlying the formation of the T-cell receptor repertoire in rheumatoid arthritis
    • Walser-Kuntz DR, Weyand CM, Weaver AJ, Ofallon WM, Goronzy JJ. Mechanisms underlying the formation of the T-cell receptor repertoire in rheumatoid arthritis. Immunity 2(6), 597-605 (1995).
    • (1995) Immunity , vol.2 , Issue.6 , pp. 597-605
    • Walser-Kuntz, D.R.1    Weyand, C.M.2    Weaver, A.J.3    Ofallon, W.M.4    Goronzy, J.J.5
  • 52
    • 0031469941 scopus 로고    scopus 로고
    • + T cells
    • DOI 10.1093/intimm/9.12.1785
    • Walser-Kuntz DR, Weyand CM, Goronzy JJ. Influence of antigenic experience on BJ gene segment usage in human CD4(+) T cells. Int. Immunol. 9(12), 1785-1792 (1997). (Pubitemid 28005816)
    • (1997) International Immunology , vol.9 , Issue.12 , pp. 1785-1792
    • Walser-Kuntz, D.R.1    Weyand, C.M.2    Goronzy, J.J.3
  • 53
    • 0027462083 scopus 로고
    • The 'side effects' of rheumatoid arthritis: Joint destruction, disability and early mortality
    • Pincus T, Callahan LF. The side-effects of rheumatoid arthritis -joint destruction, disability and early mortality. Br. J. Rheumatol. 32, 28-37 (1993). (Pubitemid 23089038)
    • (1993) British Journal of Rheumatology , vol.32 , Issue.SUPPL. 1 , pp. 28-37
    • Pincus, T.1    Callahan, L.F.2
  • 54
    • 0028978114 scopus 로고
    • Altered T-lymphocyte signaling in rheumatoid arthritis
    • Allen ME, Young SP, Michell RH, Bacon PA. Altered T-lymphocyte signaling in rheumatoid arthritis. Eur. J. Immunol. 25(6), 1547-1554 (1995).
    • (1995) Eur. J. Immunol. , vol.25 , Issue.6 , pp. 1547-1554
    • Allen, M.E.1    Young, S.P.2    Michell, R.H.3    Bacon, P.A.4
  • 55
    • 0027479456 scopus 로고
    • Defective signal transduction via T-cell receptor-CD3 structure in T cells from rheumatoid arthritis patients
    • DOI 10.1016/0198-8859(93)90111-D
    • Mirza NM, Relias V, Yunis EJ, Pachas WN, Dasgupta JD. Defective signal transduction via T-cell receptor-CD3 structure in T cells from rheumatoid arthritis patients. Hum. Immunol. 36(2), 91-98 (1993). (Pubitemid 23097302)
    • (1993) Human Immunology , vol.36 , Issue.2 , pp. 91-98
    • Mirza, N.M.1    Relias, V.2    Yunis, E.J.3    Pachas, W.N.4    Dasgupta, J.D.5
  • 57
    • 84856668777 scopus 로고    scopus 로고
    • Redox balance alterations and hyporesponsiveness of synovial T cells in rheumatoid arthritis
    • Abstract S4
    • Breedveld FC, Gringhuis SI, Maurice MM, Verweij CL. Redox balance alterations and hyporesponsiveness of synovial T cells in rheumatoid arthritis. Arthrit. Res. Ther. 1(Suppl. 1), Abstract S4 (2000).
    • (2000) Arthrit. Res. Ther. , vol.1 , Issue.SUPPL. 1
    • Breedveld, F.C.1    Gringhuis, S.I.2    Maurice, M.M.3    Verweij, C.L.4
  • 62
    • 33750343810 scopus 로고    scopus 로고
    • CTLA-4Ig suppresses reactive oxygen species by preventing synovial adherent cell-induced inactivation of Rap1, a Ras family GTPase mediator of oxidative stress in rheumatoid arthritis T cells
    • DOI 10.1002/art.22139
    • Remans PH, Wijbrandts CA, Sanders ME et al. CTLA-4IG suppresses reactive oxygen species by preventing synovial adherent cell-induced inactivation of Rap1, a Ras family GTPASE mediator of oxidative stress in rheumatoid arthritis T cells. Arthrit. Rheumat. 54(10), 3135-3143 (2006). (Pubitemid 44622084)
    • (2006) Arthritis and Rheumatism , vol.54 , Issue.10 , pp. 3135-3143
    • Remans, P.H.J.1    Wijbrandts, C.A.2    Sanders, M.E.3    Toes, R.E.4    Breedveld, F.C.5    Tak, P.P.6    Van Laar, J.M.7    Reedquist, K.A.8
  • 63
    • 78249242763 scopus 로고    scopus 로고
    • Sustained T cell Rap1 signaling is protective in the collagen-induced arthritis model of rheumatoid arthritis
    • Abreu JRF, Krausz S, Dontje W et al. Sustained T cell Rap1 signaling is protective in the collagen-induced arthritis model of rheumatoid arthritis. Arthrit. Rheumat. 62(11), 3289-3299 (2010).
    • (2010) Arthrit. Rheumat. , vol.62 , Issue.11 , pp. 3289-3299
    • Jrf, A.1    Krausz, S.2    Dontje, W.3
  • 64
    • 0037037586 scopus 로고    scopus 로고
    • A point mutation of Tyr-759 in interleukin 6 family cytokine receptor subunit gp130 causes autoimmune arthritis
    • Atsumi T, Ishihara K, Kamimura D et al. A point mutation of Tyr-759 in interleukin 6 family cytokine receptor subunit gp130 causes autoimmune arthritis. J. Exp. Med. 196(7), 979-990 (2002).
    • (2002) J. Exp. Med. , vol.196 , Issue.7 , pp. 979-990
    • Atsumi, T.1    Ishihara, K.2    Kamimura, D.3
  • 68
    • 0029095086 scopus 로고
    • Human naive T-cells activated by cytokines differentiate into a split phenotype with functional features intermediate between naive and memory T-cells
    • Unutmaz D, Baldoni F, Abrignani S. Human naive T-cells activated by cytokines differentiate into a split phenotype with functional features intermediate between naive and memory T-cells. Int. Immunol. 7, 1417-1424 (1995).
    • (1995) Int. Immunol. , vol.7 , pp. 1417-1424
    • Unutmaz, D.1    Baldoni, F.2    Abrignani, S.3
  • 69
    • 34547132777 scopus 로고    scopus 로고
    • Immunosenescence: Deficits in adaptive immunity in the elderly
    • DOI 10.1111/j.1399-0039.2007.00891.x
    • Hakim FT, Gress RE. Immunosenescence: deficits in adaptive immunity in the elderly. Tis. Antigens 70(3), 179-189 (2007). (Pubitemid 47106657)
    • (2007) Tissue Antigens , vol.70 , Issue.3 , pp. 179-189
    • Hakim, F.T.1    Gress, R.E.2
  • 70
    • 32244433673 scopus 로고    scopus 로고
    • + compartment
    • DOI 10.1016/j.mad.2005.11.001, PII S0047637405002757
    • Saule P, Trauet J, Dutriez V et al. Accumulation of memory T cells from childhood to old age: central and effector memory cells in CD4(+) versus effector memory and terminally differentiated memory cells in CD8(+) compartment. Mech. Ageing Develop. 127(3), 274-281 (2006). (Pubitemid 43214500)
    • (2006) Mechanisms of Ageing and Development , vol.127 , Issue.3 , pp. 274-281
    • Saule, P.1    Trauet, J.2    Dutriez, V.3    Lekeux, V.4    Dessaint, J.-P.5    Labalette, M.6
  • 72
    • 0027935476 scopus 로고
    • Antigen-independent activation of naive and memory resting T cells by a cytokine combination
    • DOI 10.1084/jem.180.3.1159
    • Unumtaz D, Pileri P, Abrignani S. Antigen-independent activation of naive and memory resting T-cells by a cytokine combination. J. Exp. Med. 180, 1159-1164 (1994). (Pubitemid 24256630)
    • (1994) Journal of Experimental Medicine , vol.180 , Issue.3 , pp. 1159-1164
    • Unutmaz, D.1    Pileri, P.2    Abrignani, S.3
  • 74
    • 8144221903 scopus 로고    scopus 로고
    • + memory T cells define a differentiated memory population at both the functional and transcriptional levels
    • DOI 10.1111/j.1365-2567.2004.01974.x
    • Schiott A, Lindstedt M, Johansson-Lindbom B, Roggen E, Borrebaeck CA. CD27-CD4+ memory T cells define a differentiated memory population at both the functional and transcriptional levels. Immunology 113(3), 363-370 (2004). (Pubitemid 39472153)
    • (2004) Immunology , vol.113 , Issue.3 , pp. 363-370
    • Schiott, A.1    Lindstedt, M.2    Johansson-Lindbom, B.3    Roggen, E.4    Borrebaeck, C.A.K.5
  • 75
    • 24944583626 scopus 로고    scopus 로고
    • Chemokine receptor CCR7 guides T cell exit from peripheral tissues and entry into afferent lymphatics
    • DOI 10.1038/ni1240, PII N1240
    • Bromley SK, Thomas SY, Luster AD. Chemokine receptor CCR7 guides T cell exit from peripheral tissues and entry into afferent lymphatics. Nat. Immunol. 6(9), 895-901 (2005). (Pubitemid 43090444)
    • (2005) Nature Immunology , vol.6 , Issue.9 , pp. 895-901
    • Bromley, S.K.1    Thomas, S.Y.2    Luster, A.D.3
  • 78
    • 38449099960 scopus 로고    scopus 로고
    • CD4(+)CD28(null) T cells in autoimmune disease: Pathogenic features and decreased susceptibility to immunoregulation
    • Thewissen M, Somers V, Hellings N et al. CD4(+)CD28(null) T cells in autoimmune disease: pathogenic features and decreased susceptibility to immunoregulation. J. Immunol. 179, 6514-6523 (2007).
    • (2007) J. Immunol. , vol.179 , pp. 6514-6523
    • Thewissen, M.1    Somers, V.2    Hellings, N.3
  • 79
    • 0034544566 scopus 로고    scopus 로고
    • Clonality and longevity of CD4(+)CD28(null) T cells are associated with defects in apoptotic pathways
    • Vallejo AN, Schirmer M, Weyand CM, Goronzy JJ. Clonality and longevity of CD4(+)CD28(null) T cells are associated with defects in apoptotic pathways. J. Immunol. 165(11), 6301-6307 (2000).
    • (2000) J. Immunol. , vol.165 , Issue.11 , pp. 6301-6307
    • Vallejo, A.N.1    Schirmer, M.2    Weyand, C.M.3    Goronzy, J.J.4
  • 80
    • 3242669036 scopus 로고    scopus 로고
    • + T cells - Characterization of an effector memory T-cell population in patients with rheumatoid arthritis
    • DOI 10.1111/j.0300-9475.2004.01464.x
    • Fasth AE, Cao D, van Vollenhoven R, Trollmo C, Malmstrom V. CD28(null) CD4(+) T cells -characterization of an effector memory T-cell population in patients with rheumatoid arthritis. Scand. J. Immunol. 60(1-2), 199-208 (2004). (Pubitemid 38943068)
    • (2004) Scandinavian Journal of Immunology , vol.60 , Issue.1-2 , pp. 199-208
    • Fasth, A.E.R.1    Cao, D.2    Van Vollenhoven, R.3    Trollmo, C.4    Malmstrom, V.5
  • 81
    • 0029958821 scopus 로고    scopus 로고
    • - T cells are expanded in rheumatoid arthritis and are characterized by autoreactivity
    • Schmidt D, Goronzy JJ, Weyand CM. CD4(+) CD7(-) CD28(-) T cells are expanded in rheumatoid arthritis and are characterized by autoreactivity. J. Clin. Invest. 97(9), 2027-2037 (1996). (Pubitemid 26143956)
    • (1996) Journal of Clinical Investigation , vol.97 , Issue.9 , pp. 2027-2037
    • Schmidt, D.1    Goronzy, J.J.2    Weyand, C.M.3
  • 82
    • 0030980997 scopus 로고    scopus 로고
    • Expansion of unusual CD4+ T cells in severe rheumatoid arthritis
    • DOI 10.1002/art.1780400615
    • Martens PB, Goronzy JJ, Schaid D, Weyand CM. Expansion of unusual CD4+ T cells in severe rheumatoid arthritis. Arthrit. Rheumat. 40(6), 1106-1114 (1997). (Pubitemid 27242298)
    • (1997) Arthritis and Rheumatism , vol.40 , Issue.6 , pp. 1106-1114
    • Martens, P.B.1    Goronzy, J.J.2    Schaid, D.3    Weyand, C.M.4
  • 83
    • 0033013522 scopus 로고    scopus 로고
    • Cytomegalovirus seropositivity is associated with the expansion of CD4+CD28- and CD8+CD28- T cells in rheumatoid arthritis
    • Hooper M, Kallas EG, Coffin D et al. Cytomegalovirus seropositivity is associated with the expansion of CD4+CD28-and CD8+CD28-T cells in rheumatoid arthritis. J. Rheumatol. 26(7), 1452-1457 (1999). (Pubitemid 29317864)
    • (1999) Journal of Rheumatology , vol.26 , Issue.7 , pp. 1452-1457
    • Hooper, M.1    Kallas, E.G.2    Coffin, D.3    Campbell, D.4    Evans, T.G.5    Looney, R.J.6
  • 86
    • 0035147101 scopus 로고    scopus 로고
    • CD4+,CD28- T cells in rheumatoid arthritis patients combine features of the innate and adaptive immune systems
    • DOI 10.1002/1529-0131(200101)44:1<13::AID-ANR3>3.0.CO;2-6
    • Warrington KJ, Takemura S, Goronzy JJ, Weyand CM. CD4+,CD28-T cells in rheumatoid arthritis patients combine features of the innate and adaptive immune systems. Arthrit. Rheumat. 44(1), 13-20 (2001). (Pubitemid 32113113)
    • (2001) Arthritis and Rheumatism , vol.44 , Issue.1 , pp. 13-20
    • Warrington, K.J.1    Takemura, S.2    Goronzy, J.J.3    Weyand, C.M.4
  • 90
    • 0038460241 scopus 로고    scopus 로고
    • + T cells: Reversal by interleukin-12 stimulation
    • DOI 10.1182/blood-2002-08-2574
    • Warrington KJ, Vallejo AN, Weyand CM, Goronzy JJ. CD28 loss in senescent CD4+ T cells: reversal by interleukin-12 stimulation. Blood 101(9), 3543-3549 (2003). (Pubitemid 36857940)
    • (2003) Blood , vol.101 , Issue.9 , pp. 3543-3549
    • Warrington, K.J.1    Vallejo, A.N.2    Weyand, C.M.3    Goronzy, J.J.4
  • 93
    • 0029072177 scopus 로고
    • Oligoclonal CD8+ T cells are preferentially expanded in the CD57+ subset
    • Morley JK, Batliwalla FM, Hingorani R, Gregersen PK. Oligoclonal CD8+ T cells are preferentially expanded in the CD57+ subset. J. Immunol. 154(11), 6182-6190 (1995).
    • (1995) J. Immunol. , vol.154 , Issue.11 , pp. 6182-6190
    • Morley, J.K.1    Batliwalla, F.M.2    Hingorani, R.3    Gregersen, P.K.4
  • 94
    • 0031594207 scopus 로고    scopus 로고
    • + T cells in knee joints and adjacent bone marrow of rheumatoid arthritis (RA) patients: Implication for an anti-inflammatory role
    • DOI 10.1046/j.1365-2249.1998.00511.x
    • Arai K, Yamamura S, Seki S et al. Increase of CD57(+) T cells in knee joints and adjacent bone marrow of rheumatoid arthritis (RA) patients: implication for an anti-inflammatory role. Clin. Exp. Immunol. 111(2), 345-352 (1998). (Pubitemid 28088316)
    • (1998) Clinical and Experimental Immunology , vol.111 , Issue.2 , pp. 345-352
    • Arai, K.1    Yamamura, S.2    Seki, S.3    Hanyu, T.4    Takahashi, H.E.5    Abo, T.6
  • 95
    • 0030945915 scopus 로고    scopus 로고
    • + T-cell expansions contribute to the imbalanced T-cell receptor repertoire of rheumatoid arthritis patients
    • Imberti L, Sottini A, Signorini S, Gorla R, Primi D. Oligoclonal CD4(+)CD57(+) T-cell expansions contribute to the imbalanced T-cell receptor repertoire of rheumatoid arthritis patients. Blood 89(8), 2822-2832 (1997). (Pubitemid 27172568)
    • (1997) Blood , vol.89 , Issue.8 , pp. 2822-2832
    • Imberti, L.1    Sottini, A.2    Signorini, S.3    Gorla, R.4    Primi, D.5
  • 99
    • 0035314015 scopus 로고    scopus 로고
    • Stability and commitment in T helper cell development
    • DOI 10.1016/S0952-7915(00)00210-7
    • Asnagli H, Murphy KM. Stability and commitment in T helper cell development. Curr. Opin. Immunol. 13(2), 242-247 (2001). (Pubitemid 32176045)
    • (2001) Current Opinion in Immunology , vol.13 , Issue.2 , pp. 242-247
    • Asnagli, H.1    Murphy, K.M.2
  • 100
    • 78649544524 scopus 로고    scopus 로고
    • The transient nature of the Th17 phenotype
    • Annunziato F, Romagnani S. The transient nature of the Th17 phenotype. Eur. J. Immunol. 40(12), 3312-3316 (2010).
    • (2010) Eur. J. Immunol. , vol.40 , Issue.12 , pp. 3312-3316
    • Annunziato, F.1    Romagnani, S.2
  • 101
    • 72949103063 scopus 로고    scopus 로고
    • Translational mini-review series on Th17 cells: Development of mouse and human T helper 17 cells
    • de Jong E, Suddason T, Lord GM. Translational mini-review series on Th17 cells: development of mouse and human T helper 17 cells. Clin. Exp. Immunol. 159(2), 148-158 (2010).
    • (2010) Clin. Exp. Immunol. , vol.159 , Issue.2 , pp. 148-158
    • De Jong, E.1    Suddason, T.2    Lord, G.M.3
  • 102
    • 67349200203 scopus 로고    scopus 로고
    • Balance of Th1 and Th17 effector and peripheral regulatory T cells
    • Lohr J, Knoechel B, Caretto D, Abbas AK. Balance of Th1 and Th17 effector and peripheral regulatory T cells. Microbes Infect. 11(5), 589-593 (2009).
    • (2009) Microbes Infect. , vol.11 , Issue.5 , pp. 589-593
    • Lohr, J.1    Knoechel, B.2    Caretto, D.3    Abbas, A.K.4
  • 103
    • 44049100797 scopus 로고    scopus 로고
    • Th17 cells: A new fate for differentiating helper T cells
    • Chen Z, O'Shea JJ. Th17 cells: a new fate for differentiating helper T cells. Immunol. Res. 41(2), 87-102 (2008).
    • (2008) Immunol. Res. , vol.41 , Issue.2 , pp. 87-102
    • Chen, Z.1    O'Shea, J.J.2
  • 104
    • 0033556352 scopus 로고    scopus 로고
    • Inhibition of Th1 polarization by soluble TNF receptor is dependent on antigen-presenting cell-derived IL-12
    • Becher B, Blain M, Giacomini PS, Antel JP. Inhibition of Th1 polarization by soluble TNF receptor is dependent on antigen-presenting cell-derived IL-12. J. Immunol. 162(2), 684-688 (1999). (Pubitemid 29035387)
    • (1999) Journal of Immunology , vol.162 , Issue.2 , pp. 684-688
    • Becher, B.1    Blain, M.2    Giacomini, P.S.3    Antel, J.P.4
  • 105
    • 78549271154 scopus 로고    scopus 로고
    • Increased IL-17 production by peripheral T helper cells after tumour necrosis factor blockade in rheumatoid arthritis is accompanied by inhibition of migration-associated chemokine receptor expression
    • Aerts NE, De Knop KJ, Leysen J et al. Increased IL-17 production by peripheral T helper cells after tumour necrosis factor blockade in rheumatoid arthritis is accompanied by inhibition of migration-associated chemokine receptor expression. Rheumatology 49(12), 2264-2272 (2010).
    • (2010) Rheumatology , vol.49 , Issue.12 , pp. 2264-2272
    • Aerts, N.E.1    De Knop, K.J.2    Leysen, J.3
  • 108
    • 84856673152 scopus 로고    scopus 로고
    • Defective Th1 immune response in the peripheral blood from patients with active Rheumatoid arthritis (RA): Possible contribution to tuberculosis during anti-TNF treatment
    • Kawashima M, Miossec P. Defective Th1 immune response in the peripheral blood from patients with active Rheumatoid arthritis (RA): possible contribution to tuberculosis during anti-TNF treatment. Arthrit. Rheumat. 48(9), 24 (2003).
    • (2003) Arthrit. Rheumat. , vol.48 , Issue.9 , pp. 24
    • Kawashima, M.1    Miossec, P.2
  • 109
    • 21244446635 scopus 로고    scopus 로고
    • mRNA quantification of T-bet, GATA-3, IFN-γ, and IL-4 shows a defective Th1 immune response in the peripheral blood from rheumatoid arthritis patients: Link with disease activity
    • DOI 10.1007/s10875-005-4092-4
    • Kawashima M, Miossec P. mRNA quantification of T-bet, GATA-3, IFN, and IL-4 shows a defective Th1 immune response in the peripheral blood from rheumatoid arthritis patients: link with disease activity. J. Clin. Immunol. 25(3), 209-214 (2005). (Pubitemid 40884046)
    • (2005) Journal of Clinical Immunology , vol.25 , Issue.3 , pp. 209-214
    • Kawashima, M.1    Miossec, P.2
  • 111
    • 13544262683 scopus 로고    scopus 로고
    • Dendritic cells induce MUC1 expression and polarization on human T cells by an IL-7-dependent mechanism
    • Vasir B, Avigan D, Wu Z et al. Dendritic cells induce MUC1 expression and polarization on human T cells by an IL-7-dependent mechanism. J. Immunol. 174(4), 2376-2386 (2005). (Pubitemid 40223987)
    • (2005) Journal of Immunology , vol.174 , Issue.4 , pp. 2376-2386
    • Vasir, B.1    Avigan, D.2    Wu, Z.3    Crawford, K.4    Turnquist, S.5    Ren, J.6    Kufe, D.7
  • 112
    • 84856645089 scopus 로고    scopus 로고
    • Aglycosyl anti-CD3 monoclonal antibody therapy in rheumatoid arthritis -results of a pilot safety study
    • Abstract i24
    • Lawson C, Griffiths B, Ponchel F et al. Aglycosyl anti-CD3 monoclonal antibody therapy in rheumatoid arthritis -results of a pilot safety study. Rheumatology 44(S1), Abstract i24 (2005).
    • (2005) Rheumatology , vol.44
    • Lawson, C.1    Griffiths, B.2    Ponchel, F.3
  • 113
    • 44849125718 scopus 로고    scopus 로고
    • IL-7 in rheumatoid arthritis
    • Churchman S, Ponchel F. IL-7 in rheumatoid arthritis. Rheumatology 6, 753-759 (2008).
    • (2008) Rheumatology , vol.6 , pp. 753-759
    • Churchman, S.1    Ponchel, F.2
  • 114
    • 44849083026 scopus 로고    scopus 로고
    • T-bet expression in RA patients with early, DMARDs naive disease is low and correlates with low levels of IL-7 and T-cell dysfunctions
    • Ponchel F, Brown AK, Field SL et al. T-bet expression in RA patients with early, DMARDs naive disease is low and correlates with low levels of IL-7 and T-cell dysfunctions. Arthrit. Rheumat. Abstract S525(2004).
    • (2004) Arthrit. Rheumat. Abstract
    • Ponchel, F.1    Brown, A.K.2    Field, S.L.3
  • 115
    • 1842441520 scopus 로고    scopus 로고
    • Differentiation of naive CD4(+) T cells towards T helper 2 cells is not impaired in rheumatoid arthritis patients
    • van Roon JAG, Glaudemans CA, Bijlsma JWJ, Lafeber F. Differentiation of naive CD4(+) T cells towards T helper 2 cells is not impaired in rheumatoid arthritis patients. Arthrit. Res. Ther. 5(5), R269-R276 (2003).
    • (2003) Arthrit. Res. Ther. , vol.5 , Issue.5
    • Van Roon Jag1    Glaudemans, C.A.2    Jwj, B.3    Lafeber, F.4
  • 116
    • 0031885819 scopus 로고    scopus 로고
    • Blockade of IL-12 during the induction of collagen-induced arthritis (CIA) markedly attenuates the severity of the arthritis
    • DOI 10.1046/j.1365-2249.1998.00485.x
    • Malfait AM, Butler DM, Presky DH et al. Blockade of IL-12 during the induction of collagen-induced arthritis (CIA) markedly attenuates the severity of the arthritis. Clin. Exp. Immunol. 111(2), 377-383 (1998). (Pubitemid 28088321)
    • (1998) Clinical and Experimental Immunology , vol.111 , Issue.2 , pp. 377-383
    • Malfait, A.M.1    Butler, D.M.2    Presky, D.H.3    Maini, R.N.4    Brennan, F.M.5    Feldmann, M.6
  • 117
    • 0033041866 scopus 로고    scopus 로고
    • Anti-IL-12 and anti-TNF antibodies synergistically suppress the progression of murine collagen-induced arthritis
    • DOI 10.1002/(SICI)1521-4141(199907)29:07<2205::AID-IMMU2205>3.0. CO;2-Z
    • Butler DM, Malfait AM, Maini RN, Brennan FM, Feldmann M. Anti-IL-12 and anti-TNF antibodies synergistically suppress the progression of murine collagen-induced arthritis. Eur. J. Immunol. 29(7), 2205-2212 (1999). (Pubitemid 29313095)
    • (1999) European Journal of Immunology , vol.29 , Issue.7 , pp. 2205-2212
    • Butler, D.M.1    Malfait, A.-M.2    Maini, R.N.3    Brennan, F.M.4    Feldmann, M.5
  • 121
    • 55149090692 scopus 로고    scopus 로고
    • Th17 cytokines and mucosal immunity
    • Dubin PJ, Kolls JK. Th17 cytokines and mucosal immunity. Immunol. Rev. 226, 160-171 (2008).
    • (2008) Immunol. Rev. , vol.226 , pp. 160-171
    • Dubin, P.J.1    Kolls, J.K.2
  • 122
    • 65549165389 scopus 로고    scopus 로고
    • In vivo activated monocytes from the site of inflammation in humans specifically promote Th17 responses
    • Evans HG, Gullick NJ, Kelly S et al. In vivo activated monocytes from the site of inflammation in humans specifically promote Th17 responses. Proc. Natl Acad. Sci. USA 106(15), 6232-6237 (2009).
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , Issue.15 , pp. 6232-6237
    • Evans, H.G.1    Gullick, N.J.2    Kelly, S.3
  • 123
    • 68849125507 scopus 로고    scopus 로고
    • Type 17 T helper cells origins, features and possible roles in rheumatic disease
    • Annunziato F, Cosmi L, Liotta F, Maggi E, Romagnani S. Type 17 T helper cells origins, features and possible roles in rheumatic disease. Nat. Rev. Rheumatol. 5(6), 325-331 (2009).
    • (2009) Nat. Rev. Rheumatol. , vol.5 , Issue.6 , pp. 325-331
    • Annunziato, F.1    Cosmi, L.2    Liotta, F.3    Maggi, E.4    Romagnani, S.5
  • 124
    • 54949139265 scopus 로고    scopus 로고
    • The phenotype of human T(h)17 cells and their precursors, the cytokines that mediate their differentiation and the role of T(h)17 cells in inflammation
    • Annunziato F, Cosmi L, Liotta F, Maggi E, Romagnani S. The phenotype of human T(h)17 cells and their precursors, the cytokines that mediate their differentiation and the role of T(h)17 cells in inflammation. Int. Immunol. 20(11), 1361-1368 (2008).
    • (2008) Int. Immunol. , vol.20 , Issue.11 , pp. 1361-1368
    • Annunziato, F.1    Cosmi, L.2    Liotta, F.3    Maggi, E.4    Romagnani, S.5
  • 125
    • 33748499140 scopus 로고    scopus 로고
    • Serum amyloid A is an endogenous ligand that differentially induces IL-12 and IL-23
    • He R, Shepard LW, Chen J, Pan ZK, Ye RD. Serum amyloid A is an endogenous ligand that differentially induces IL-12 and IL-23. J. Immunol. 177(6), 4072-4079 (2006). (Pubitemid 44359941)
    • (2006) Journal of Immunology , vol.177 , Issue.6 , pp. 4072-4079
    • He, R.1    Shepard, L.W.2    Chen, J.3    Pan, Z.K.4    Ye, R.D.5
  • 127
    • 0033926254 scopus 로고    scopus 로고
    • Contribution of interleukin 17 to synovium matrix destruction in rheumatoid arthritis
    • DOI 10.1006/cyto.2000.0681
    • Chabaud M, Garnero P, Dayer JM et al. Contribution of interleukin 17 to synovium matrix destruction in rheumatoid arthritis. Cytokine 12(7), 1092-1099 (2000). (Pubitemid 30479493)
    • (2000) Cytokine , vol.12 , Issue.7 , pp. 1092-1099
    • Chabaud, M.1    Garnero, P.2    Dayer, J.-M.3    Guerne, P.-A.4    Fossiez, F.5    Miossec, P.6
  • 128
    • 0034041595 scopus 로고    scopus 로고
    • Stimulation of 92-kd gelatinase (matrix metalloproteinase 9) production by interleukin-17 in human monocyte/macrophages: A possible role in rheumatoid arthritis
    • DOI 10.1002/1529-0131(200005)43:5<1134::AID-ANR24>3.0.CO;2-#
    • Jovanovic DV, Martel-Pelletier J, Di Battista JA et al. Stimulation of 92-kd gelatinase (matrix metalloproteinase 9) production by interleukin-17 in human monocyte/macrophages: a possible role in rheumatoid arthritis. Arthrit. Rheumat. 43(5), 1134-1144 (2000). (Pubitemid 30368194)
    • (2000) Arthritis and Rheumatism , vol.43 , Issue.5 , pp. 1134-1144
    • Jovanovic, D.V.1    Martel-Pelletier, J.2    Di Battista, J.A.3    Mineau, F.4    Jolicoeur, F.-C.5    Benderdour, M.6    Pelletier, J.-P.7
  • 129
    • 0037388342 scopus 로고    scopus 로고
    • T cells regulate the expression of matrix metalloproteinase in human osteoblasts via a dual mitogen-activated protein kinase mechanism
    • DOI 10.1002/art.10872
    • Rifas L, Arackal S. T cells regulate the expression of matrix metalloproteinase in human osteoblasts via a dual mitogen-activated protein kinase mechanism. Arthrit. Rheumat. 48(4), 993-1001 (2003). (Pubitemid 36418241)
    • (2003) Arthritis and Rheumatism , vol.48 , Issue.4 , pp. 993-1001
    • Rifas, L.1    Arackal, S.2
  • 130
    • 56749151293 scopus 로고    scopus 로고
    • Th17 cells in immunity and autoimmunity
    • Oukka M. Th17 cells in immunity and autoimmunity. Ann. Rheumat. Dis. 67(Suppl. 3), iii26-iii29 (2008).
    • (2008) Ann. Rheumat. Dis. , vol.67 , Issue.SUPPL. 3
    • Oukka, M.1
  • 132
    • 0344585384 scopus 로고    scopus 로고
    • Suppression of Immune Induction of Collagen-Induced Arthritis in IL-17-Deficient Mice
    • Nakae S, Nambu A, Sudo K, Iwakura Y. Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice. J. Immunol. 171(11), 6173-6177 (2003). (Pubitemid 37467240)
    • (2003) Journal of Immunology , vol.171 , Issue.11 , pp. 6173-6177
    • Nakae, S.1    Nambu, A.2    Sudo, K.3    Iwakura, Y.4
  • 134
    • 38949197817 scopus 로고    scopus 로고
    • IL-17/Th17 targeting: On the road to prevent chronic destructive arthritis?
    • Lubberts E. IL-17/Th17 targeting: on the road to prevent chronic destructive arthritis? Cytokine 41(2), 84-91 (2008).
    • (2008) Cytokine , vol.41 , Issue.2 , pp. 84-91
    • Lubberts, E.1
  • 136
    • 51349111163 scopus 로고    scopus 로고
    • An overview of IL-17 function and signaling
    • Gaffen SL. An overview of IL-17 function and signaling. Cytokine 43(3), 402-407 (2008).
    • (2008) Cytokine , vol.43 , Issue.3 , pp. 402-407
    • Gaffen, S.L.1
  • 137
    • 77957377044 scopus 로고    scopus 로고
    • Rheumatoid synovial fluid interleukin-17-producing CD4 T cells have abundant tumor necrosis factor-?co-expression, but little interleukin-22 and interleukin-23R expression
    • Church LD, Filer AD, Hidalgo E et al. Rheumatoid synovial fluid interleukin-17-producing CD4 T cells have abundant tumor necrosis factor-?co-expression, but little interleukin-22 and interleukin-23R expression. Arthrit. Res. Ther. 12(5), R184 (2010).
    • (2010) Arthrit. Res. Ther. , vol.12 , Issue.5
    • Church, L.D.1    Filer, A.D.2    Hidalgo, E.3
  • 138
    • 45349099788 scopus 로고    scopus 로고
    • Cytokines secreted in response to toll-like receptor ligand stimulation modulate differentiation of human Th17 cells
    • DOI 10.1002/art.23497
    • Kattah MG, Wong MT, Yocum MD, Utz PJ. Cytokines secreted in response to toll-like receptor ligand stimulation modulate differentiation of human Th17 cells. Arthrit. Rheumat. 58(6), 1619-1629 (2008). (Pubitemid 351847515)
    • (2008) Arthritis and Rheumatism , vol.58 , Issue.6 , pp. 1619-1629
    • Kattah, M.G.1    Wong, M.T.2    Yocum, M.D.3    Utz, P.J.4
  • 139
    • 74849095189 scopus 로고    scopus 로고
    • 1,25-dihydroxyvitamin D-3 modulates Th17 polarization and interleukin-22 expression by memory T cells from patients with early rheumatoid arthritis
    • Colin EM, Asmawidjaja PS, van Hamburg JP et al. 1,25-dihydroxyvitamin D-3 modulates Th17 polarization and interleukin-22 expression by memory T cells from patients with early rheumatoid arthritis. Arthrit. Rheumat. 62(1), 132-142 (2011).
    • (2011) Arthrit. Rheumat. , vol.62 , Issue.1 , pp. 132-142
    • Colin, E.M.1    Asmawidjaja, P.S.2    Van Hamburg, J.P.3
  • 140
    • 79952140342 scopus 로고    scopus 로고
    • The vitamin D3 1?-hydroxylase gene and its regulation by active vitamin D3
    • Takeyama K, Kato S. The vitamin D3 1?-hydroxylase gene and its regulation by active vitamin D3. Biosci. Biotechnol. Biochem. 75(2), 208-213 (2011).
    • (2011) Biosci. Biotechnol. Biochem. , vol.75 , Issue.2 , pp. 208-213
    • Takeyama, K.1    Kato, S.2
  • 141
    • 77951636478 scopus 로고    scopus 로고
    • Cutting edge: Mast cells express IL-17A in rheumatoid arthritis synovium
    • Hueber AJ, Asquith DL, Miller AM et al. Cutting edge: mast cells express IL-17A in rheumatoid arthritis synovium. J. Immunol. 184(7), 3336-3340 (2010).
    • (2010) J. Immunol. , vol.184 , Issue.7 , pp. 3336-3340
    • Hueber, A.J.1    Asquith, D.L.2    Miller, A.M.3
  • 142
    • 60549110257 scopus 로고    scopus 로고
    • Immune regulation of bone loss by Th17 cells
    • Adamopoulos IE, Bowman EP. Immune regulation of bone loss by Th17 cells. Arthrit. Res. Ther. 10(5), 225 (2008).
    • (2008) Arthrit. Res. Ther. , vol.10 , Issue.5 , pp. 225
    • Adamopoulos, I.E.1    Bowman, E.P.2
  • 144
    • 78650245903 scopus 로고    scopus 로고
    • Are Th17 cells an appropriate new target in the treatment of rheumatoid arthritis?
    • Kato H, Fox DA. Are Th17 cells an appropriate new target in the treatment of rheumatoid arthritis? Clin. Trans. Sci. 3(6), 319-326 (2010).
    • (2010) Clin. Trans. Sci. , vol.3 , Issue.6 , pp. 319-326
    • Kato, H.1    Fox, D.A.2
  • 146
    • 74549179138 scopus 로고    scopus 로고
    • Interferons direct Th2 cell reprogramming to generate a stable GATA-3(+)T-bet(+) cell subset with combined Th2 and Th1 cell functions
    • Hegazy AN, Peine M, Helmstetter C et al. Interferons direct Th2 cell reprogramming to generate a stable GATA-3(+)T-bet(+) cell subset with combined Th2 and Th1 cell functions. Immunity 32(1), 116-128 (2010).
    • (2010) Immunity , vol.32 , Issue.1 , pp. 116-128
    • Hegazy, A.N.1    Peine, M.2    Helmstetter, C.3
  • 148
    • 73149118287 scopus 로고    scopus 로고
    • Identification of a novel subset of human circulating memory CD4(+) T cells that produce both IL-17A and IL-4
    • Cosmi L, Maggi L, Santarlasci V et al. Identification of a novel subset of human circulating memory CD4(+) T cells that produce both IL-17A and IL-4. J. Allergy Clin. Immunol. 125(1), 222-230.e1-e4 (2010).
    • (2010) J. Allergy Clin. Immunol. , vol.125 , Issue.1
    • Cosmi, L.1    Maggi, L.2    Santarlasci, V.3
  • 149
    • 56349093347 scopus 로고    scopus 로고
    • IL-4 inhibits TGF-? -induced Foxp3+ T cells and, together with TGF-, generates IL-9+ IL-10+ Foxp3(-) effector T cells
    • Dardalhon V, Awasthi A, Kwon H et al. IL-4 inhibits TGF-? -induced Foxp3+ T cells and, together with TGF-, generates IL-9+ IL-10+ Foxp3(-) effector T cells. Nat. Immunol. 9(12), 1347-1355 (2008).
    • (2008) Nat. Immunol. , vol.9 , Issue.12 , pp. 1347-1355
    • Dardalhon, V.1    Awasthi, A.2    Kwon, H.3
  • 150
    • 56349154943 scopus 로고    scopus 로고
    • Transforming growth factor-? "reprograms" the differentiation of T helper 2 cells and promotes an interleukin 9-producing subset
    • Veldhoen M, Uyttenhove C, van Snick J et al. Transforming growth factor-? "reprograms" the differentiation of T helper 2 cells and promotes an interleukin 9-producing subset. Nat. Immunol. 9(12), 1341-1346 (2008).
    • (2008) Nat. Immunol. , vol.9 , Issue.12 , pp. 1341-1346
    • Veldhoen, M.1    Uyttenhove, C.2    Van Snick, J.3
  • 151
    • 68149179251 scopus 로고    scopus 로고
    • IL-9 as a mediator of Th17-driven inflammatory disease
    • Nowak EC, Weaver CT, Turner H et al. IL-9 as a mediator of Th17-driven inflammatory disease. J. Exp. Med. 206(8), 1653-1660 (2009).
    • (2009) J. Exp. Med. , vol.206 , Issue.8 , pp. 1653-1660
    • Nowak, E.C.1    Weaver, C.T.2    Turner, H.3
  • 152
    • 67651171182 scopus 로고    scopus 로고
    • Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from T(H)-17, T(H)1 and T(H)2 cells
    • Trifari S, Kaplan CD, Tran EH, Crellin NK, Spits H. Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from T(H)-17, T(H)1 and T(H)2 cells. Nat. Immunol. 10(8), 864-871 (2009).
    • (2009) Nat. Immunol. , vol.10 , Issue.8 , pp. 864-871
    • Trifari, S.1    Kaplan, C.D.2    Tran, E.H.3    Crellin, N.K.4    Spits, H.5
  • 153
    • 69149107148 scopus 로고    scopus 로고
    • IL-9 induces differentiation of TH17 cells and enhances function of FoxP3+ natural regulatory T cells
    • Elyaman W, Bradshaw EM, Uyttenhove C et al. IL-9 induces differentiation of TH17 cells and enhances function of FoxP3+ natural regulatory T cells. Proc. Natl Acad. Sci. USA 106(31), 12885-12890 (2009).
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , Issue.31 , pp. 12885-12890
    • Elyaman, W.1    Bradshaw, E.M.2    Uyttenhove, C.3
  • 154
    • 77952584843 scopus 로고    scopus 로고
    • The transcription factor PU.1 is required for the development of IL-9-producing T cells and allergic inflammation
    • Chang HC, Sehra S, Goswami R et al. The transcription factor PU.1 is required for the development of IL-9-producing T cells and allergic inflammation. Nat. Immunol. 11(6), 527-534 (2010).
    • (2010) Nat. Immunol. , vol.11 , Issue.6 , pp. 527-534
    • Chang, H.C.1    Sehra, S.2    Goswami, R.3
  • 155
    • 77955288962 scopus 로고    scopus 로고
    • Effector and regulatory T-cell subsets in autoimmunity and tissue inflammation
    • Jager A, Kuchroo VK. Effector and regulatory T-cell subsets in autoimmunity and tissue inflammation. Scand. J. Immunol. 72(3), 173-184 (2010).
    • (2010) Scand. J. Immunol. , vol.72 , Issue.3 , pp. 173-184
    • Jager, A.1    Kuchroo, V.K.2
  • 156
    • 72849131815 scopus 로고    scopus 로고
    • Th22 cells represent a distinct human T cell subset involved in epidermal immunity and remodeling
    • Eyerich S, Eyerich K, Pennino D et al. Th22 cells represent a distinct human T cell subset involved in epidermal immunity and remodeling. J. Clin. Invest. 119(12), 3573-3585 (2009).
    • (2009) J. Clin. Invest. , vol.119 , Issue.12 , pp. 3573-3585
    • Eyerich, S.1    Eyerich, K.2    Pennino, D.3
  • 157
    • 80555150814 scopus 로고    scopus 로고
    • Elevated Th22 cells correlated with Th17 cells in patients with rheumatoid arthritis
    • Zhang L, Li JM, Liu XG et al. Elevated Th22 cells correlated with Th17 cells in patients with rheumatoid arthritis. J. Clin. Immunol. 31(4), 606-614 (2011).
    • (2011) J. Clin. Immunol. , vol.31 , Issue.4 , pp. 606-614
    • Zhang, L.1    Li, J.M.2    Liu, X.G.3
  • 158
    • 79959255489 scopus 로고    scopus 로고
    • Th22 in inflammatory and autoimmune disease: Prospects for therapeutic intervention
    • Zhang N, Pan HF, Ye DQ. Th22 in inflammatory and autoimmune disease: prospects for therapeutic intervention. Mol. Cell Biochem. 353(1-2), 41-46 (2011).
    • (2011) Mol. Cell Biochem. , vol.353 , Issue.1-2 , pp. 41-46
    • Zhang, N.1    Pan, H.F.2    Ye, D.Q.3
  • 159
    • 0034606359 scopus 로고    scopus 로고
    • Follicular B helper T cells express CXC chemokine receptor 5, localize to B cell follicles, and support immunoglobulin production
    • Breitfeld D, Ohl L, Kremmer E et al. Follicular B helper T cells express CXC chemokine receptor 5, localize to B cell follicles, and support immunoglobulin production. J. Exp. Med. 192(11), 1545-1552 (2000).
    • (2000) J. Exp. Med. , vol.192 , Issue.11 , pp. 1545-1552
    • Breitfeld, D.1    Ohl, L.2    Kremmer, E.3
  • 160
    • 0034606348 scopus 로고    scopus 로고
    • CXC chemokine receptor 5 expression defines follicular homing T cells with B cell helper function
    • Schaerli P, Willimann K, Lang AB et al. CXC chemokine receptor 5 expression defines follicular homing T cells with B cell helper function. J. Exp. Med. 192(11), 1553-1562 (2000).
    • (2000) J. Exp. Med. , vol.192 , Issue.11 , pp. 1553-1562
    • Schaerli, P.1    Willimann, K.2    Lang, A.B.3
  • 161
    • 69249101229 scopus 로고    scopus 로고
    • Bcl6 mediates the development of T follicular helper cells
    • Nurieva RI, Chung Y, Martinez GJ et al. Bcl6 mediates the development of T follicular helper cells. Science 325(5943), 1001-1005 (2009).
    • (2009) Science , vol.325 , Issue.5943 , pp. 1001-1005
    • Nurieva, R.I.1    Chung, Y.2    Martinez, G.J.3
  • 162
    • 69249109601 scopus 로고    scopus 로고
    • Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation
    • Johnston RJ, Poholek AC, DiToro D et al. Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation. Science 325(5943), 1006-1010 (2009).
    • (2009) Science , vol.325 , Issue.5943 , pp. 1006-1010
    • Johnston, R.J.1    Poholek, A.C.2    Ditoro, D.3
  • 163
    • 16244399808 scopus 로고    scopus 로고
    • Rheumatoid arthritis
    • DOI 10.1111/j.0105-2896.2005.00245.x
    • Goronzy JJ, Weyand CM. Rheumatoid arthritis. Immunol. Rev. 204, 55-73 (2005). (Pubitemid 40460493)
    • (2005) Immunological Reviews , vol.204 , pp. 55-73
    • Goronzy, J.J.1    Weyand, C.M.2
  • 164
    • 34248573325 scopus 로고    scopus 로고
    • Ectopic Lymphoid-Organ Development Occurs through Interleukin 7-Mediated Enhanced Survival of Lymphoid-Tissue-Inducer Cells
    • DOI 10.1016/j.immuni.2007.04.009, PII S1074761307002555
    • Meier D, Bornmann C, Chappaz S et al. Ectopic lymphoid-organ development occurs through interleukin 7-mediated enhanced survival of lymphoid-tissue- inducer cells. Immunity 26(5), 643-654 (2007). (Pubitemid 46756355)
    • (2007) Immunity , vol.26 , Issue.5 , pp. 643-654
    • Meier, D.1    Bornmann, C.2    Chappaz, S.3    Schmutz, S.4    Otten, L.A.5    Ceredig, R.6    Acha-Orbea, H.7    Finke, D.8
  • 165
    • 34547726636 scopus 로고    scopus 로고
    • Inflammation and ectopic lymphoid structures in rheumatoid arthritis synovial tissues dissected by genomics technology: Identification of the interleukin-7 signaling pathway in tissues with lymphoid neogenesis
    • DOI 10.1002/art.22748
    • Timmer TC, Baltus B, Vondenhoff M et al. Inflammation and ectopic lymphoid structures in rheumatoid arthritis synovial tissues dissected by genomics technology: identification of the interleukin-7 signaling pathway in tissues with lymphoid neogenesis. Arthrit. Rheumat. 56(8), 2492-2502 (2007). (Pubitemid 47237268)
    • (2007) Arthritis and Rheumatism , vol.56 , Issue.8 , pp. 2492-2502
    • Timmer, T.C.G.1    Baltus, B.2    Vondenhoff, M.3    Huizinga, T.W.J.4    Tak, P.P.5    Verweij, C.L.6    Mebius, R.E.7    Van Der Pouw Kraan, T.C.T.M.8
  • 166
    • 0024589097 scopus 로고
    • Organ-specific autoimmune disease induced in mice by elimination of T cell subsets: V. Neonatal administration of cyclosporin A causes autoimmune disease
    • Sakaguchi S, Sakaguchi N. Organ-specific autoimmune-disease induced in mice by elimination of T-cell subsets: neonatal administration of cyclosporine-a causes autoimmune-disease. J. Immunol. 142(2), 471-480 (1989). (Pubitemid 19039964)
    • (1989) Journal of Immunology , vol.142 , Issue.2 , pp. 471-480
    • Sakaguchi, S.1    Sakaguchi, N.2
  • 167
    • 0029150110 scopus 로고
    • Immunological self-tolerance maintained by activated T-cells expressing Il-2 receptor ?-Chains (Cd25) -breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
    • Sakaguchi S, Sakaguchi N, Asano M, Itoh M, Toda M. Immunological self-tolerance maintained by activated T-cells expressing Il-2 receptor ?-Chains (Cd25) -breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J. Immunol. 155(3), 1151-1164 (1995).
    • (1995) J. Immunol. , vol.155 , Issue.3 , pp. 1151-1164
    • Sakaguchi, S.1    Sakaguchi, N.2    Asano, M.3    Itoh, M.4    Toda, M.5
  • 168
    • 0017172518 scopus 로고
    • Role of T lymphocytes in adjuvant arthritis. I. Evidence for the regulatory function of thymus-derived cells in the induction of the disease
    • Kayashima K, Koga T, Onoue K. Role of T lymphocytes in adjuvant arthritis. I. Evidence for the regulatory function of thymus-derived cells in the induction of the disease. J. Immunol. 117(5), 1878-1882 (1976).
    • (1976) J. Immunol. , vol.117 , Issue.5 , pp. 1878-1882
    • Kayashima, K.1    Koga, T.2    Onoue, K.3
  • 170
    • 0018184734 scopus 로고
    • Isolation and characterization of naturally occurring subclasses of human peripheral blood T cells with regulatory functions
    • Strelkauskas AJ, Schauf V, Wilson BS, Chess L, Schlossman SF. Isolation and characterization of naturally occurring subclasses of human peripheral blood T cells with regulatory functions. J. Immunol. 120(4), 1278-1282 (1978). (Pubitemid 8343832)
    • (1978) Journal of Immunology , vol.120 , Issue.4 , pp. 1278-1282
    • Strelkauskas, A.J.1    Schauf, V.2    Wilson, B.S.3
  • 171
    • 0021926791 scopus 로고
    • Immunoregulatory T cell circuits in man. Identification of a distinct T cell subpopulation of the helper/inducer lineage that amplifies the development of alloantigen-specific suppressor T cells
    • Damle NK, Mohagheghpour N, Kansas GS, Fishwild DM, Engleman EG. Immunoregulatory T cell circuits in man. Identification of a distinct T cell subpopulation of the helper/inducer lineage that amplifies the development of alloantigen-specific suppressor T cells. J. Immunol. 134(1), 235-243 (1985). (Pubitemid 15191503)
    • (1985) Journal of Immunology , vol.134 , Issue.1 , pp. 235-243
    • Damle, N.K.1    Mohagheghpour, N.2    Kansas, G.S.3
  • 172
    • 0022640618 scopus 로고
    • Functional characterization of a regulatory human T-cell subpopulation increasing during autologous MLR
    • Cosulich ME, Risso A, Canonica GW, Bargellesi A. Functional characterization of a regulatory human T-cell subpopulation increasing during autologous MLR. Immunology 57(2), 265-273 (1986). (Pubitemid 16135741)
    • (1986) Immunology , vol.57 , Issue.2 , pp. 265-273
    • Cosulich, M.E.1    Risso, A.2    Canonica, G.W.3    Bargellesi, A.4
  • 173
    • 0020033915 scopus 로고
    • Concanavalin A induces suppressor cell activity in both Tγ and T(non-γ) cells: Most of the suppressor cells do not carry HLA-DR antigens
    • DOI 10.1111/j.1365-3083.1982.tb00625.x
    • Dobloug JH, Forre O, Chattopadhyay C, Natvig JB. Concanavalin A induces suppressor cell activity in both T ? and T non-? cells: most of the suppressor cells do not carry HLA-DR antigens. Scand. J. Immunol. 15(1), 87-95 (1982). (Pubitemid 12150679)
    • (1982) Scandinavian Journal of Immunology , vol.15 , Issue.1 , pp. 87-95
    • Dobloug, J.H.1    Forre, O.2    Chattopadhyay, C.3    Natvig, J.B.4
  • 175
    • 0019457969 scopus 로고
    • Con A-induced suppressor cell activity and T-lymphocyte subpopulations in peripheral blood lymphocytes of patients with rheumatoid arthritis and juvenile rheumatoid arthritis
    • DOI 10.1111/j.1365-3083.1981.tb00146.x
    • Dobloug JH, Chattopadhyay C, Forre O, Hoyeraal HM, Natvig JB. Con A-induced suppressor cell activity and T-lymphocyte subpopulations in peripheral blood lymphocytes of patients with rheumatoid arthritis and juvenile rheumatoid arthritis. Scand. J. Immunol. 13(4), 367-373 (1981). (Pubitemid 11147255)
    • (1981) Scandinavian Journal of Immunology , vol.13 , Issue.4 , pp. 367-373
    • Dobloug, J.H.1    Chattopadhyay, C.2    Forre, O.3
  • 176
    • 0019904006 scopus 로고
    • Nonspecific suppressor function in rheumatoid arthritis
    • Panush RS. Nonspecific suppressor function in rheumatoid arthritis. J. Clin. Lab. Immunol. 9(1), 59-64 (1982). (Pubitemid 12004321)
    • (1982) Journal of Clinical and Laboratory Immunology , vol.9 , Issue.1 , pp. 59-64
    • Panush, R.S.1
  • 177
    • 0019986712 scopus 로고
    • Lymphocyte studies in rheumatoid arthritis. V. Suppressor cell function in peripheral blood
    • Patel V, Panayi GS, Shepherd P et al. Lymphocyte studies in rheumatoid arthritis. V. Suppressor cell function in peripheral blood. Scand. J. Rheumatol. 11(3), 133-137 (1982). (Pubitemid 12030865)
    • (1982) Scandinavian Journal of Rheumatology , vol.11 , Issue.3 , pp. 133-137
    • Patel, V.1    Panayi, G.S.2    Sheperd, P.3
  • 179
    • 0024805934 scopus 로고
    • A CD4 cell is capable of transferring suppression of collagen-induced arthritis
    • Myers LK, Stuart JM, Kang AH. A CD4 cell is capable of transferring suppression of collagen-induced arthritis. J. Immunol. 143(12), 3976-3980 (1989). (Pubitemid 20012582)
    • (1989) Journal of Immunology , vol.143 , Issue.12 , pp. 3976-3980
    • Myers, L.K.1    Stuart, J.M.2    Kang, A.H.3
  • 180
    • 0023189244 scopus 로고
    • Induction of CD4 suppressor T cells with anti-leu-8 antibody
    • Kanof ME, Strober W, James SP. Induction of CD4 suppressor T cells with anti-Leu-8 antibody. J. Immunol. 139(1), 49-54 (1987). (Pubitemid 17091759)
    • (1987) Journal of Immunology , vol.139 , Issue.1 , pp. 49-54
    • Kanof, M.E.1    Strober, W.2    James, S.P.3
  • 181
    • 0025977347 scopus 로고
    • Monoclonal antibody against the human peripheral lymph node homing receptor homologue (Leu 8) inhibits B cell differentiation but not B cell proliferation
    • Murakawa Y, Strober W, James SP. Monoclonal antibody against the human peripheral lymph node homing receptor homologue (Leu 8) inhibits B cell differentiation but not B cell proliferation. J. Immunol. 146(1), 40-46 (1991).
    • (1991) J. Immunol. , vol.146 , Issue.1 , pp. 40-46
    • Murakawa, Y.1    Strober, W.2    James, S.P.3
  • 182
    • 0022996016 scopus 로고
    • Selective loss of suppressor T cells in rheumatoid arthritis patients: Analysis of peripheral blood lymphocytes by 2-dimensional flow cytometry
    • Goto M, Miyamoto T, Nishioka K, Okumura K. Selective loss of suppressor T cells in rheumatoid arthritis patients: analysis of peripheral blood lymphocytes by 2-dimensional flow cytometry. J. Rheumatol. 13(5), 853-857 (1986). (Pubitemid 17203913)
    • (1986) Journal of Rheumatology , vol.13 , Issue.5 , pp. 853-857
    • Goto, M.1    Miyamoto, T.2    Nishioka, K.3    Okumura, K.4
  • 183
    • 1842732224 scopus 로고    scopus 로고
    • + Regulatory T Cells in Patients with Multiple Sclerosis
    • DOI 10.1084/jem.20031579
    • Viglietta V, Baecher-Allan C, Weiner HL, Hafler DA. Loss of functional suppression by CD4(+)CD25(+) regulatory T cells in patients with multiple sclerosis. J. Exp. Med. 199(7), 971-979 (2004). (Pubitemid 38481088)
    • (2004) Journal of Experimental Medicine , vol.199 , Issue.7 , pp. 971-979
    • Viglietta, V.1    Baecher-Allan, C.2    Weiner, H.L.3    Hafler, D.A.4
  • 186
    • 0037025943 scopus 로고    scopus 로고
    • + regulatory T cells suppress lethal acute graft-versus-host disease after allogeneic bone marrow transplantation
    • DOI 10.1084/jem.20020399
    • Hoffmann P, Ermann J, Edinger M, Fathman CG, Strober S. Donor-type CD4(+)CD25(+) regulatory T cells suppress lethal acute graft-versus-host disease after allogeneic bone marrow transplantation. J. Exp. Med. 196(3), 389-399 (2002). (Pubitemid 34875667)
    • (2002) Journal of Experimental Medicine , vol.196 , Issue.3 , pp. 389-399
    • Hoffmann, P.1    Ermann, J.2    Edinger, M.3    Garrison Fathman, C.4    Strober, S.5
  • 189
    • 0037364976 scopus 로고    scopus 로고
    • Regulatory T cells in transplantation tolerance
    • DOI 10.1038/nri1027
    • Wood KJ, Sakaguchi S. Regulatory T cells in transplantation tolerance. Nat. Rev. Immunol. 3(3), 199-210 (2003). (Pubitemid 37323205)
    • (2003) Nature Reviews Immunology , vol.3 , Issue.3 , pp. 199-210
    • Wood, K.J.1    Sakaguchi, S.2
  • 190
    • 0036379814 scopus 로고    scopus 로고
    • Regulation of tumour immunity by CD25(+) T cells
    • Gallimore A, Sakaguchi S. Regulation of tumour immunity by CD25(+) T cells. Immunology 107(1), 5-9 (2002).
    • (2002) Immunology , vol.107 , Issue.1 , pp. 5-9
    • Gallimore, A.1    Sakaguchi, S.2
  • 191
    • 2242423605 scopus 로고    scopus 로고
    • + regulatory T cells control Leishmania major persistence and immunity
    • DOI 10.1038/nature01152
    • Belkaid Y, Piccirillo CA, Mendez S, Shevach EM, Sacks DL. CD4(+)CD25(+) regulatory T cells control Leishmania major persistence and immunity. Nature 420(6915), 502-507 (2002). (Pubitemid 35477041)
    • (2002) Nature , vol.420 , Issue.6915 , pp. 502-507
    • Belkaid, Y.1    Piccirillo, C.A.2    Mendez, S.3    Shevach, E.M.4    Sacks, D.L.5
  • 192
    • 1942456867 scopus 로고    scopus 로고
    • + regulatory T-cell deficiency in patients with hepatitis C-mixed cryoglobulinemia vasculitis
    • DOI 10.1182/blood-2003-07-2598
    • Boyer O, Saadoun D, Abriol J et al. CD4(+) CD25(+) regulatory T-cell deficiency in patients with hepatitis C-mixed cryoglobulinemia vasculitis. Blood 103(9), 3428-3430 (2004). (Pubitemid 38525674)
    • (2004) Blood , vol.103 , Issue.9 , pp. 3428-3430
    • Boyer, O.1    Saadoun, D.2    Abriol, J.3    Dodille, M.4    Piette, J.-C.5    Cacoub, P.6    Klatzmann, D.7
  • 193
    • 0036774801 scopus 로고    scopus 로고
    • Regulatory T cells in transplantation
    • DOI 10.1016/S0952-7915(02)00379-5
    • Karim M, Bushell AR, Wood KJ. Regulatory T cells in transplantation. Curr. Opin. Immunol. 14(5), 584-591 (2002). (Pubitemid 35232145)
    • (2002) Current Opinion in Immunology , vol.14 , Issue.5 , pp. 584-591
    • Karim, M.1    Bushell, A.R.2    Wood, K.J.3
  • 194
    • 17644384896 scopus 로고    scopus 로고
    • + T cells with the phenotypic and functional characteristics of regulatory T cells are enriched in the synovial fluid of patients with rheumatoid arthritis
    • DOI 10.1111/j.1365-2249.2005.02754.x
    • Mottonen M, Heikkinen J, Mustonen L et al. CD4(+) CD25(+) T cells with the phenotypic and functional characteristics of regulatory T cells are enriched in the synovial fluid of patients with rheumatoid arthritis. Clin. Exp. Immunol. 140(2), 360-367 (2005). (Pubitemid 40559165)
    • (2005) Clinical and Experimental Immunology , vol.140 , Issue.2 , pp. 360-367
    • Mottonen, M.1    Heikkinen, J.2    Mustonen, L.3    Isomaki, P.4    Luukkainen, R.5    Lassila, O.6
  • 195
    • 4444300314 scopus 로고    scopus 로고
    • CD4+CD25+ regulatory T cells in rheumatoid arthritis: Differences in the presence, phenotype, and function between peripheral blood and synovial fluid
    • DOI 10.1002/art.20499
    • van Amelsfort JMR, Jacobs KMG, Bijlsma JWJ, Lafeber F, Taams LS. CD4+CD25+ regulatory T cells in rheumatoid arthritis -differences in the presence, phenotype, and function between peripheral blood and synovial fluid. Arthrit. Rheumat. 50(9), 2775-2785 (2004). (Pubitemid 39209514)
    • (2004) Arthritis and Rheumatism , vol.50 , Issue.9 , pp. 2775-2785
    • Van Amelsfort, J.M.R.1    Jacobs, K.M.G.2    Bijlsma, J.W.J.3    Lafeber, F.P.J.G.4    Taams, L.S.5
  • 196
    • 79952787680 scopus 로고    scopus 로고
    • FoxP3(+) CD4(+) T cells in systemic autoimmune diseases: The delicate balance between true regulatory T cells and effector Th-17 cells
    • Abdulahad WH, Boots AMH, Kallenberg CGM. FoxP3(+) CD4(+) T cells in systemic autoimmune diseases: the delicate balance between true regulatory T cells and effector Th-17 cells. Rheumatology 50(4), 646-656 (2011).
    • (2011) Rheumatology , vol.50 , Issue.4 , pp. 646-656
    • Abdulahad, W.H.1    Boots, A.M.H.2    Kallenberg, C.G.M.3
  • 199
    • 58049196774 scopus 로고    scopus 로고
    • Defects in CTLA-4 are associated with abnormal regulatory T cell function in rheumatoid arthritis
    • Flores-Borja F, Jury EC, Mauri C, Ehrenstein MR. Defects in CTLA-4 are associated with abnormal regulatory T cell function in rheumatoid arthritis. Proc. Natl Acad. Sci. USA 105(49), 19396-19401 (2008).
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , Issue.49 , pp. 19396-19401
    • Flores-Borja, F.1    Jury, E.C.2    Mauri, C.3    Ehrenstein, M.R.4
  • 204
    • 77956042108 scopus 로고    scopus 로고
    • RA patients in remission on TNF blockers: When and in whom can TNF blocker therapy be stopped? Ann
    • Saleem B, Keen H, Goeb V et al. RA patients in remission on TNF blockers: when and in whom can TNF blocker therapy be stopped? Ann. Rheum. Dis. 69(9), 1636-1642 (2010).
    • (2010) Rheum. Dis. , vol.69 , Issue.9 , pp. 1636-1642
    • Saleem, B.1    Keen, H.2    Goeb, V.3
  • 205
    • 79952671514 scopus 로고    scopus 로고
    • CD4(+) CD25(+)Foxp3(+) regulatory T cell content in peripheral blood and synovial fluid of patients with rheumatoid arthritis and osteoarthritis
    • Hong Q, Song XY, Huang JY, Guo Y. CD4(+) CD25(+)Foxp3(+) regulatory T cell content in peripheral blood and synovial fluid of patients with rheumatoid arthritis and osteoarthritis. Chin. J. Biol. 24(2), 169-172 (2011).
    • (2011) Chin. J. Biol. , vol.24 , Issue.2 , pp. 169-172
    • Hong, Q.1    Song, X.Y.2    Huang, J.Y.3    Guo, Y.4
  • 206
    • 77953639101 scopus 로고    scopus 로고
    • Regulatory T cells protect from local and systemic bone destruction in arthritis
    • Zaiss MM, Frey B, Hess A et al. Regulatory T cells protect from local and systemic bone destruction in arthritis. J. Immunol. 184(12), 7238-7246 (2010).
    • (2010) J. Immunol. , vol.184 , Issue.12 , pp. 7238-7246
    • Zaiss, M.M.1    Frey, B.2    Hess, A.3
  • 208
    • 55149094300 scopus 로고    scopus 로고
    • Human CD25highFoxp3pos regulatory T cells differentiate into IL-17-producing cells
    • Koenen HJ, Smeets RL, Vink PM et al. Human CD25highFoxp3pos regulatory T cells differentiate into IL-17-producing cells. Blood 112(6), 2340-2352 (2008).
    • (2008) Blood , vol.112 , Issue.6 , pp. 2340-2352
    • Koenen, H.J.1    Smeets, R.L.2    Vink, P.M.3
  • 209
    • 15244361536 scopus 로고    scopus 로고
    • CD25(bright) CD4(+) regulatory T cells are enriched in inflamed joints of patients with chronic rheumatic disease
    • Cao DJ, van Vollenhoven R, Klareskog L, Trollmo C, Malmstrom V. CD25(bright) CD4(+) regulatory T cells are enriched in inflamed joints of patients with chronic rheumatic disease. Arthrit. Res. Ther. 6(4), R335-R346 (2004).
    • (2004) Arthrit. Res. Ther. , vol.6 , Issue.4
    • Cao, D.J.1    Van Vollenhoven, R.2    Klareskog, L.3    Trollmo, C.4    Malmstrom, V.5
  • 210
    • 34249799285 scopus 로고    scopus 로고
    • - T cells or are self-induced to become Th17 cells in the absence of exogenous TGF-β
    • Xu L, Kitani A, Fuss I, Strober W. Cutting edge: regulatory T cells induce CD4+CD25-Foxp3-T cells or are self-induced to become Th17 cells in the absence of exogenous TGF. J. Immunol. 178(11), 6725-6729 (2007). (Pubitemid 46847395)
    • (2007) Journal of Immunology , vol.178 , Issue.11 , pp. 6725-6729
    • Xu, L.1    Kitani, A.2    Fuss, I.3    Strober, W.4
  • 211
    • 55549084247 scopus 로고    scopus 로고
    • Retinoic acid enhances Foxp3 induction indirectly by relieving inhibition from CD4+CD44hi Cells
    • Hill JA, Hall JA, Sun CM et al. Retinoic acid enhances Foxp3 induction indirectly by relieving inhibition from CD4+CD44hi Cells. Immunity 29(5), 758-770 (2008).
    • (2008) Immunity , vol.29 , Issue.5 , pp. 758-770
    • Hill, J.A.1    Hall, J.A.2    Sun, C.M.3
  • 212
    • 70350478405 scopus 로고    scopus 로고
    • Retinoic acid can enhance conversion of naive into regulatory T cells independently of secreted cytokines
    • Nolting J, Daniel C, Reuter S et al. Retinoic acid can enhance conversion of naive into regulatory T cells independently of secreted cytokines. J. Exp. Med. 206(10), 2131-2139 (2009).
    • (2009) J. Exp. Med. , vol.206 , Issue.10 , pp. 2131-2139
    • Nolting, J.1    Daniel, C.2    Reuter, S.3
  • 213
    • 78049373227 scopus 로고    scopus 로고
    • Cutting edge: All-trans retinoic acid sustains the stability and function of natural regulatory T cells in an inflammatory milieu
    • Zhou XH, Kong N, Wang J et al. Cutting edge: all-trans retinoic acid sustains the stability and function of natural regulatory T cells in an inflammatory milieu. J. Immunol. 185(5), 2675-2679 (2010).
    • (2010) J. Immunol. , vol.185 , Issue.5 , pp. 2675-2679
    • Zhou, X.H.1    Kong, N.2    Wang, J.3
  • 214
    • 0030732828 scopus 로고    scopus 로고
    • Haemopoietic stem cell transplantation for autoimmune diseases
    • Snowden JA, Brooks PM, Biggs JC. Haemopoietic stem cell transplantation for autoimmune diseases. Br. J. Haematol. 99(1), 9-22 (1997). (Pubitemid 27461321)
    • (1997) British Journal of Haematology , vol.99 , Issue.1 , pp. 9-22
    • Snowden, J.A.1    Brooks, P.M.2    Biggs, J.C.3
  • 215
    • 0026783632 scopus 로고
    • Humanized monoclonal-antibody therapy for rheumatoid-arthritis
    • Isaacs JD, Watts RA, Hazleman BL et al. Humanized monoclonal-antibody therapy for rheumatoid-arthritis. Lancet 340(8822), 748-752 (1992).
    • (1992) Lancet , vol.340 , Issue.8822 , pp. 748-752
    • Isaacs, J.D.1    Watts, R.A.2    Hazleman, B.L.3
  • 216
    • 0029129542 scopus 로고
    • Emergence of oligoclonal T-cell populations following therapeutic T-cell depletion in rheumatoid-arthritis
    • Jendro MC, Ganten T, Matteson EL, Weyand CM, Goronzy JJ. Emergence of oligoclonal T-cell populations following therapeutic T-cell depletion in rheumatoid-arthritis. Arthrit. Rheumat. 38(9), 1242-1251 (1995).
    • (1995) Arthrit. Rheumat. , vol.38 , Issue.9 , pp. 1242-1251
    • Jendro, M.C.1    Ganten, T.2    Matteson, E.L.3    Weyand, C.M.4    Goronzy, J.J.5
  • 217
    • 84856628340 scopus 로고
    • Treating rheumatoid arthritis with a non-depleting anti-Cd4 monoclonal antibody (Mab)
    • Moreland LW, Bucy RP, Knowles RW et al. Treating rheumatoid arthritis with a non-depleting anti-Cd4 monoclonal antibody (Mab). Arthrit. Rheumat. 38(9), 199-199 (1995).
    • (1995) Arthrit. Rheumat. , vol.38 , Issue.9 , pp. 199-199
    • Moreland, L.W.1    Bucy, R.P.2    Knowles, R.W.3
  • 220
    • 0030819475 scopus 로고    scopus 로고
    • ICAM-1/LFA-1 expression in acute osteodestructive joint lesions in collagen-induced arthritis in rats
    • Seidel M, Keck R, Vetter H. ICAM-1/LFA-1 expression in acute osteodestructive joint lesions in collagen-induced arthritis in rats. J. Histochem. Cytochem. 45, 1247-1254 (1997).
    • (1997) J. Histochem. Cytochem. , vol.45 , pp. 1247-1254
    • Seidel, M.1    Keck, R.2    Vetter, H.3
  • 222
    • 84856637734 scopus 로고    scopus 로고
    • Naïve T-cells predict MTX induced remission in early arthritis
    • Amsterdam, The Netherlands 3-6 March 2011
    • Ponchel F, Parmar R, Nam J et al. Naïve T-cells predict MTX induced remission in early arthritis. Presented at: 31st European Workshop for Rheumatology Research. Amsterdam, The Netherlands, 3-6 March 2011.
    • 31st European Workshop for Rheumatology Research
    • Ponchel, F.1    Parmar, R.2    Nam, J.3
  • 223
    • 14144250887 scopus 로고    scopus 로고
    • Effect of treatment of rheumatoid arthritis with infliximab on IFNγ, IL4, T-bet, and GATA-3 expression: Link with improvement of systemic inflammation and disease activity
    • DOI 10.1136/ard.2004.022731
    • Kawashima M, Miossec P. Effect of treatment of rheumatoid arthritis with infliximab on IFN, IL4, T-bet, and GATA-3 expression: link with improvement of systemic inflammation and disease activity. Ann. Rheumat. Dis. 64(3), 415-418 (2005). (Pubitemid 40283052)
    • (2005) Annals of the Rheumatic Diseases , vol.64 , Issue.3 , pp. 415-418
    • Kawashima, M.1    Miossec, P.2
  • 224
    • 84856670315 scopus 로고    scopus 로고
    • Regulatory and naive t cell numbers increase after rituximab therapy in rheumatoid arthritis
    • Abstract S523
    • Vital EM, El Sherbiny Y, Parmar R, Emery P, Ponchel F. Regulatory and naive t cell numbers increase after rituximab therapy in rheumatoid arthritis. Ann. Rheum. Dis. 70(3)Abstract S523 (2011).
    • (2011) Ann. Rheum. Dis. , vol.70 , Issue.3
    • Vital, E.M.1    El Sherbiny, Y.2    Parmar, R.3    Emery, P.4    Ponchel, F.5
  • 225
    • 79954989313 scopus 로고    scopus 로고
    • Atorvastatin upregulates regulatory T cells and reduces clinical disease activity in patients with rheumatoid arthritis
    • Tang TT, Song Y, Ding YJ et al. Atorvastatin upregulates regulatory T cells and reduces clinical disease activity in patients with rheumatoid arthritis. J. Lipid Res. 52(5), 1023-1032 (2011).
    • (2011) J. Lipid Res. , vol.52 , Issue.5 , pp. 1023-1032
    • Tang, T.T.1    Song, Y.2    Ding, Y.J.3
  • 227
    • 79953114328 scopus 로고    scopus 로고
    • Regulatory T-cell adoptive immunotherapy: Potential for treatment of autoimmunity
    • Wright GP, Ehrenstein MR, Stauss HJ. Regulatory T-cell adoptive immunotherapy: potential for treatment of autoimmunity. Exp. Rev. Clin. Immunol. 7(2), 213-225 (2011).
    • (2011) Exp. Rev. Clin. Immunol. , vol.7 , Issue.2 , pp. 213-225
    • Wright, G.P.1    Ehrenstein, M.R.2    Stauss, H.J.3


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