Blockade of IL-12 during the induction of collagen-induced arthritis (CIA) markedly attenuates the severity of the arthritis

Clinical and Experimental Immunology

Volumn 111, Issue 2, 1998, Pages 377-383

  Malfait, A M ^a   Butler, D M ^a   Presky, D H ^b   Maini, R N ^a   Brennan, F M ^a   Feldmann, M ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b HOFFMANN LA ROCHE INC   (United States)

Author keywords

Collagen induced arthritis; Cytokines; IL 12

Indexed keywords

COLLAGEN; CYTOKINE ANTIBODY; FREUND ADJUVANT; INTERLEUKIN 12; NEUTRALIZING ANTIBODY;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTHRITIS; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; HELPER CELL; INFLAMMATION; INTERFERON INDUCTION; MALE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SYNOVIOCYTE;

ANIMALS; ANTIBODIES; ANTIBODIES, MONOCLONAL; ARTHRITIS, EXPERIMENTAL; COLLAGEN; CYTOKINES; INTERFERON TYPE II; INTERLEUKIN-12; LYMPH NODES; MALE; MICE; MICE, INBRED DBA; STIMULATION, CHEMICAL; TH1 CELLS;

EID: 0031885819     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2249.1998.00485.x     Document Type: Article

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