-
1
-
-
0024353079
-
TH1 and TH2 cells: Different patterns of lymphokine secretion lead to different functional properties
-
Mosmann TR, Coffman RL. TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu Rev Immunol 1989 7 : 145 173.
-
(1989)
Annu Rev Immunol
, vol.7
, pp. 145-173
-
-
Mosmann, T.R.1
Coffman, R.L.2
-
2
-
-
0026601932
-
Inflammatory leukocytes and cytokines in the peptide-induced disease of experimental allergic encephalomyelitis in SJL and B10.PL mice
-
Merrill JE, Kono DH, Clayton J, Ando DG, Hinton DR, Hofman FM. Inflammatory leukocytes and cytokines in the peptide-induced disease of experimental allergic encephalomyelitis in SJL and B10.PL mice. Proc Natl Acad Sci U S A 1992 89 : 574 578.
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, pp. 574-578
-
-
Merrill, J.E.1
Kono, D.H.2
Clayton, J.3
Ando, D.G.4
Hinton, D.R.5
Hofman, F.M.6
-
3
-
-
0024368359
-
Encephalitogenic T cells in the B10.PL model of experimental allergic encephalomyelitis (EAE) are of the Th-1 lymphokine subtype
-
Ando DG, Clayton J, Kono D, Urban JL, Sercarz EE. Encephalitogenic T cells in the B10.PL model of experimental allergic encephalomyelitis (EAE) are of the Th-1 lymphokine subtype. Cell Immunol 1989 124 : 132 143.
-
(1989)
Cell Immunol
, vol.124
, pp. 132-143
-
-
Ando, D.G.1
Clayton, J.2
Kono, D.3
Urban, J.L.4
Sercarz, E.E.5
-
4
-
-
0023677710
-
Multiple sclerosis: Involvement of interferons in lesion pathogenesis
-
Traugott U, Lebon P. Multiple sclerosis: involvement of interferons in lesion pathogenesis. Ann Neurol 1988 24 : 243 251.
-
(1988)
Ann Neurol
, vol.24
, pp. 243-251
-
-
Traugott, U.1
Lebon, P.2
-
5
-
-
0027427223
-
Cytokines and adhesion molecules contribute to the ability of myelin proteolipid protein-specific T cell clones to mediate experimental allergic encephalomyelitis
-
Kuchroo VK, Martin CA, Greer JM, Ju ST, Sobel RA, Dorf ME. Cytokines and adhesion molecules contribute to the ability of myelin proteolipid protein-specific T cell clones to mediate experimental allergic encephalomyelitis. J Immunol 1993 151 : 4371 4382.
-
(1993)
J Immunol
, vol.151
, pp. 4371-4382
-
-
Kuchroo, V.K.1
Martin, C.A.2
Greer, J.M.3
Ju, S.T.4
Sobel, R.A.5
Dorf, M.E.6
-
6
-
-
0027529932
-
Surface expression of alpha 4 integrin by CD4 T cells is required for their entry into brain parenchyma
-
Baron J, Madri J, Ruddle N, Hashim G, Janeway C Jr. Surface expression of alpha 4 integrin by CD4 T cells is required for their entry into brain parenchyma. J Exp Med 1993 177 : 57 68.
-
(1993)
J Exp Med
, vol.177
, pp. 57-68
-
-
Baron, J.1
Madri, J.2
Ruddle, N.3
Hashim, G.4
Janeway, Jr.C.5
-
7
-
-
0023221133
-
Treatment of multiple sclerosis with gamma interferon: Exacerbations associated with activation of the immune system
-
Panitch HS, Hirsch RL, Schindler J, Johnson KP. Treatment of multiple sclerosis with gamma interferon: exacerbations associated with activation of the immune system. Neurology 1987 37 : 1097 1102.
-
(1987)
Neurology
, vol.37
, pp. 1097-1102
-
-
Panitch, H.S.1
Hirsch, R.L.2
Schindler, J.3
Johnson, K.P.4
-
8
-
-
0033033469
-
Induction of interferon-gamma production in Th1 CD4+ T cells: Evidence for two distinct pathways for promoter activation
-
Yang J, Murphy TL, Ouyang W, Murphy KM. Induction of interferon-gamma production in Th1 CD4+ T cells: evidence for two distinct pathways for promoter activation. Eur J Immunol 1999 29 : 548 555.
-
(1999)
Eur J Immunol
, vol.29
, pp. 548-555
-
-
Yang, J.1
Murphy, T.L.2
Ouyang, W.3
Murphy, K.M.4
-
9
-
-
3142724732
-
Loss of T-bet, but not STAT1, prevents the development of experimental autoimmune encephalomyelitis
-
Bettelli E, Sullivan B, Szabo SJ, Sobel RA, Glimcher LH, Kuchroo VK. Loss of T-bet, but not STAT1, prevents the development of experimental autoimmune encephalomyelitis. J Exp Med 2004 200 : 79 87.
-
(2004)
J Exp Med
, vol.200
, pp. 79-87
-
-
Bettelli, E.1
Sullivan, B.2
Szabo, S.J.3
Sobel, R.A.4
Glimcher, L.H.5
Kuchroo, V.K.6
-
10
-
-
0034789247
-
Effect of targeted disruption of STAT4 and STAT6 on the induction of experimental autoimmune encephalomyelitis
-
Chitnis T, Najafian N, Benou C et al. Effect of targeted disruption of STAT4 and STAT6 on the induction of experimental autoimmune encephalomyelitis. J Clin Invest 2001 108 : 739 747.
-
(2001)
J Clin Invest
, vol.108
, pp. 739-747
-
-
Chitnis, T.1
Najafian, N.2
Benou, C.3
-
11
-
-
0036885067
-
The lineage decisions of helper T cells
-
Murphy KM, Reiner SL. The lineage decisions of helper T cells. Nat Rev Immunol 2002 2 : 933 944.
-
(2002)
Nat Rev Immunol
, vol.2
, pp. 933-944
-
-
Murphy, K.M.1
Reiner, S.L.2
-
12
-
-
0036233983
-
Transcription: Tantalizing times for T cells
-
Ho IC, Glimcher LH. Transcription: tantalizing times for T cells. Cell 2002 109 (Suppl. S109 20.
-
(2002)
Cell
, vol.109
, Issue.SUPPL.
, pp. 109-120
-
-
Ho, I.C.1
Glimcher, L.H.2
-
13
-
-
0030810155
-
The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells
-
Zheng W, Flavell RA. The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells. Cell 1997 89 : 587 596.
-
(1997)
Cell
, vol.89
, pp. 587-596
-
-
Zheng, W.1
Flavell, R.A.2
-
14
-
-
0030604714
-
The proto-oncogene c-maf is responsible for tissue-specific expression of interleukin-4
-
Ho IC, Hodge MR, Rooney JW, Glimcher LH. The proto-oncogene c-maf is responsible for tissue-specific expression of interleukin-4. Cell 1996 85 : 973 983.
-
(1996)
Cell
, vol.85
, pp. 973-983
-
-
Ho, I.C.1
Hodge, M.R.2
Rooney, J.W.3
Glimcher, L.H.4
-
15
-
-
0042062277
-
IL-4 and many roads to lupuslike autoimmunity
-
Singh RR. IL-4 and many roads to lupuslike autoimmunity. Clin Immunol 2003 108 : 73 9.
-
(2003)
Clin Immunol
, vol.108
, pp. 73-79
-
-
Singh, R.R.1
-
16
-
-
0030739650
-
Myelin basic protein-specific T helper 2 (Th2) cells cause experimental autoimmune encephalomyelitis in immunodeficient hosts rather than protect them from the disease
-
Lafaille JJ, Keere FV, Hsu AL et al. Myelin basic protein-specific T helper 2 (Th2) cells cause experimental autoimmune encephalomyelitis in immunodeficient hosts rather than protect them from the disease. J Exp Med 1997 186 : 307 312.
-
(1997)
J Exp Med
, vol.186
, pp. 307-312
-
-
Lafaille, J.J.1
Keere, F.V.2
Hsu, A.L.3
-
17
-
-
0007179779
-
Autopathogenic T helper cell type 1 (Th1) and protective Th2 clones differ in their recognition of the autoantigenic peptide of myelin proteolipid protein
-
Das MP, Nicholson LB, Greer JM, Kuchroo VK. Autopathogenic T helper cell type 1 (Th1) and protective Th2 clones differ in their recognition of the autoantigenic peptide of myelin proteolipid protein. J Exp Med 1997 186 : 867 876.
-
(1997)
J Exp Med
, vol.186
, pp. 867-876
-
-
Das, M.P.1
Nicholson, L.B.2
Greer, J.M.3
Kuchroo, V.K.4
-
18
-
-
73349109145
-
Th1, Th17, and Th9 effector cells induce experimental autoimmune encephalomyelitis with different pathological phenotypes
-
Jäger A, Dardalhon V, Sobel RA, Bettelli E, Kuchroo VK. Th1, Th17, and Th9 effector cells induce experimental autoimmune encephalomyelitis with different pathological phenotypes. J Immunol 2009 183 : 7169 7177.
-
(2009)
J Immunol
, vol.183
, pp. 7169-7177
-
-
Jäger, A.1
Dardalhon, V.2
Sobel, R.A.3
Bettelli, E.4
Kuchroo, V.K.5
-
19
-
-
34447529095
-
Glatiramer acetate: Mechanisms of action in multiple sclerosis
-
Schrempf W, Ziemssen T. Glatiramer acetate: mechanisms of action in multiple sclerosis. Autoimmun Rev 2007 6 : 469 475.
-
(2007)
Autoimmun Rev
, vol.6
, pp. 469-475
-
-
Schrempf, W.1
Ziemssen, T.2
-
20
-
-
0029671318
-
Mice with a disrupted IFN-gamma gene are susceptible to the induction of experimental autoimmune encephalomyelitis (EAE)
-
Ferber IA, Brocke S, Taylor-Edwards C et al. Mice with a disrupted IFN-gamma gene are susceptible to the induction of experimental autoimmune encephalomyelitis (EAE). J Immunol 1996 156 : 5 7.
-
(1996)
J Immunol
, vol.156
, pp. 5-7
-
-
Ferber, I.A.1
Brocke, S.2
Taylor-Edwards, C.3
-
21
-
-
0031570381
-
IFN-gamma-deficient mice develop experimental autoimmune uveitis in the context of a deviant effector response
-
Jones LS, Rizzo LV, Agarwal RK et al. IFN-gamma-deficient mice develop experimental autoimmune uveitis in the context of a deviant effector response. J Immunol 1997 158 : 5997 6005.
-
(1997)
J Immunol
, vol.158
, pp. 5997-6005
-
-
Jones, L.S.1
Rizzo, L.V.2
Agarwal, R.K.3
-
22
-
-
0031826252
-
Anti-IL-12 antibody prevents the development and progression of collagen-induced arthritis in IFN-gamma receptor-deficient mice
-
Matthys P, Vermeire K, Mitera T, Heremans H, Huang S, Billiau A. Anti-IL-12 antibody prevents the development and progression of collagen-induced arthritis in IFN-gamma receptor-deficient mice. Eur J Immunol 1998 28 : 2143 2151.
-
(1998)
Eur J Immunol
, vol.28
, pp. 2143-2151
-
-
Matthys, P.1
Vermeire, K.2
Mitera, T.3
Heremans, H.4
Huang, S.5
Billiau, A.6
-
23
-
-
0033638507
-
Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12
-
Oppmann B, Lesley R, Blom B et al. Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12. Immunity 2000 13 : 715 725.
-
(2000)
Immunity
, vol.13
, pp. 715-725
-
-
Oppmann, B.1
Lesley, R.2
Blom, B.3
-
24
-
-
0037434789
-
Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain
-
Cua DJ, Sherlock J, Chen Y et al. Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain. Nature 2003 421 : 744 748.
-
(2003)
Nature
, vol.421
, pp. 744-748
-
-
Cua, D.J.1
Sherlock, J.2
Chen, Y.3
-
25
-
-
13244283212
-
IL-23 drives a pathogenic T cell population that induces autoimmune inflammation
-
Langrish CL, Chen Y, Blumenschein WM et al. IL-23 drives a pathogenic T cell population that induces autoimmune inflammation. J Exp Med 2005 201 : 233 240.
-
(2005)
J Exp Med
, vol.201
, pp. 233-240
-
-
Langrish, C.L.1
Chen, Y.2
Blumenschein, W.M.3
-
26
-
-
45749101727
-
Induction and effector functions of T(H)17 cells
-
Bettelli E, Korn T, Oukka M, Kuchroo VK. Induction and effector functions of T(H)17 cells. Nature 2008 453 : 1051 1057.
-
(2008)
Nature
, vol.453
, pp. 1051-1057
-
-
Bettelli, E.1
Korn, T.2
Oukka, M.3
Kuchroo, V.K.4
-
27
-
-
0344389016
-
Interleukin-17 mRNA expression in blood and CSF mononuclear cells is augmented in multiple sclerosis
-
Matusevicius D, Kivisakk P, He B et al. Interleukin-17 mRNA expression in blood and CSF mononuclear cells is augmented in multiple sclerosis. Mult Scler 1999 5 : 101 104.
-
(1999)
Mult Scler
, vol.5
, pp. 101-104
-
-
Matusevicius, D.1
Kivisakk, P.2
He, B.3
-
28
-
-
0033083111
-
IL-17 is produced by some proinflammatory Th1/Th0 cells but not by Th2 cells
-
Aarvak T, Chabaud M, Miossec P, Natvig JB. IL-17 is produced by some proinflammatory Th1/Th0 cells but not by Th2 cells. J Immunol 1999 162 : 1246 1251.
-
(1999)
J Immunol
, vol.162
, pp. 1246-1251
-
-
Aarvak, T.1
Chabaud, M.2
Miossec, P.3
Natvig, J.B.4
-
29
-
-
0031691282
-
Interleukin-17 and interferon-gamma synergize in the enhancement of proinflammatory cytokine production by human keratinocytes
-
Teunissen MB, Koomen CW, de Waal Malefyt R, Wierenga EA, Bos JD. Interleukin-17 and interferon-gamma synergize in the enhancement of proinflammatory cytokine production by human keratinocytes. J Invest Dermatol 1998 111 : 645 649.
-
(1998)
J Invest Dermatol
, vol.111
, pp. 645-649
-
-
Teunissen, M.B.1
Koomen, C.W.2
De Waal Malefyt, R.3
Wierenga, E.A.4
Bos, J.D.5
-
30
-
-
30944452780
-
Therapeutic efficacy of IL-17 neutralization in murine experimental autoimmune encephalomyelitis
-
Hofstetter HH, Ibrahim SM, Koczan D et al. Therapeutic efficacy of IL-17 neutralization in murine experimental autoimmune encephalomyelitis. Cell Immunol 2005 237 : 123 130.
-
(2005)
Cell Immunol
, vol.237
, pp. 123-130
-
-
Hofstetter, H.H.1
Ibrahim, S.M.2
Koczan, D.3
-
31
-
-
0344585384
-
Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice
-
Nakae S, Nambu A, Sudo K, Iwakura Y. Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice. J Immunol 2003 171 : 6173 6177.
-
(2003)
J Immunol
, vol.171
, pp. 6173-6177
-
-
Nakae, S.1
Nambu, A.2
Sudo, K.3
Iwakura, Y.4
-
32
-
-
58149231532
-
Differential roles of interleukin-17A and -17F in host defense against mucoepithelial bacterial infection and allergic responses
-
Ishigame H, Kakuta S, Nagai T et al. Differential roles of interleukin-17A and -17F in host defense against mucoepithelial bacterial infection and allergic responses. Immunity 2009 30 : 108 119.
-
(2009)
Immunity
, vol.30
, pp. 108-119
-
-
Ishigame, H.1
Kakuta, S.2
Nagai, T.3
-
33
-
-
33646577466
-
Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
-
Bettelli E, Carrier Y, Gao W et al. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature 2006 441 : 235 238.
-
(2006)
Nature
, vol.441
, pp. 235-238
-
-
Bettelli, E.1
Carrier, Y.2
Gao, W.3
-
34
-
-
32244442562
-
TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells
-
Veldhoen M, Hocking RJ, Atkins CJ, Locksley RM, Stockinger B. TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells. Immunity 2006 24 : 179 189.
-
(2006)
Immunity
, vol.24
, pp. 179-189
-
-
Veldhoen, M.1
Hocking, R.J.2
Atkins, C.J.3
Locksley, R.M.4
Stockinger, B.5
-
35
-
-
33646560950
-
Transforming growth factor-b induces development of Th17 lineage
-
Mangan PR, Harrington LE, O'Quinn DB et al. Transforming growth factor-b induces development of Th17 lineage. Nature 2006 441 : 231 234.
-
(2006)
Nature
, vol.441
, pp. 231-234
-
-
Mangan, P.R.1
Harrington, L.E.2
O'Quinn, D.B.3
-
36
-
-
34247593586
-
STAT3 regulates cytokine-mediated generation of inflammatory helper T cells
-
Yang XO, Panopoulos AD, Nurieva R et al. STAT3 regulates cytokine-mediated generation of inflammatory helper T cells. J Biol Chem 2007 282 : 9358 9363.
-
(2007)
J Biol Chem
, vol.282
, pp. 9358-9363
-
-
Yang, X.O.1
Panopoulos, A.D.2
Nurieva, R.3
-
37
-
-
34547232503
-
IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cells
-
Korn T, Bettelli E, Gao W et al. IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cells. Nature 2007 448 : 484 487.
-
(2007)
Nature
, vol.448
, pp. 484-487
-
-
Korn, T.1
Bettelli, E.2
Gao, W.3
-
38
-
-
34547204946
-
Essential autocrine regulation by IL-21 in the generation of inflammatory T cells
-
Nurieva R, Yang XO, Martinez G et al. Essential autocrine regulation by IL-21 in the generation of inflammatory T cells. Nature 2007 448 : 480 483.
-
(2007)
Nature
, vol.448
, pp. 480-483
-
-
Nurieva, R.1
Yang, X.O.2
Martinez, G.3
-
39
-
-
34547188748
-
IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways
-
Zhou L, Ivanov II, Spolski R et al. IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways. Nat Immunol 2007 8 : 967 974.
-
(2007)
Nat Immunol
, vol.8
, pp. 967-974
-
-
Zhou, L.1
Ivanov, I.I.2
Spolski, R.3
-
40
-
-
58549094107
-
IRF4 is essential for IL-21-mediated induction, amplification, and stabilization of the Th17 phenotype
-
Huber M, Brustle A, Reinhard K et al. IRF4 is essential for IL-21-mediated induction, amplification, and stabilization of the Th17 phenotype. Proc Natl Acad Sci U S A 2008 105 : 20846 20851.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 20846-20851
-
-
Huber, M.1
Brustle, A.2
Reinhard, K.3
-
41
-
-
34548128307
-
The development of inflammatory T(H)-17 cells requires interferon-regulatory factor 4
-
Brüstle A, Heink S, Huber M et al. The development of inflammatory T(H)-17 cells requires interferon-regulatory factor 4. Nat Immunol 2007 8 : 958 966.
-
(2007)
Nat Immunol
, vol.8
, pp. 958-966
-
-
Brüstle, A.1
Heink, S.2
Huber, M.3
-
42
-
-
57449105853
-
IRF-4-binding protein inhibits interleukin-17 and interleukin-21 production by controlling the activity of IRF-4 transcription factor
-
Chen Q, Yang W, Gupta S et al. IRF-4-binding protein inhibits interleukin-17 and interleukin-21 production by controlling the activity of IRF-4 transcription factor. Immunity 2008 29 : 899 911.
-
(2008)
Immunity
, vol.29
, pp. 899-911
-
-
Chen, Q.1
Yang, W.2
Gupta, S.3
-
43
-
-
64049089798
-
Critical regulation of early Th17 cell differentiation by interleukin-1 signaling
-
Chung Y, Chang SH, Martinez GJ et al. Critical regulation of early Th17 cell differentiation by interleukin-1 signaling. Immunity 2009 30 : 576 587.
-
(2009)
Immunity
, vol.30
, pp. 576-587
-
-
Chung, Y.1
Chang, S.H.2
Martinez, G.J.3
-
44
-
-
44049104564
-
The differentiation of human T(H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammat
-
Manel N, Unutmaz D, Littman DR. The differentiation of human T(H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammat. Nat Immunol 2008 9 : 641 649.
-
(2008)
Nat Immunol
, vol.9
, pp. 641-649
-
-
Manel, N.1
Unutmaz, D.2
Littman, D.R.3
-
45
-
-
47549112840
-
IL-21 and TGF-beta are required for differentiation of human T(H)17 cells
-
Yang L, Anderson DE, Baecher-Allan C et al. IL-21 and TGF-beta are required for differentiation of human T(H)17 cells. Nature 2008 454 : 350 352.
-
(2008)
Nature
, vol.454
, pp. 350-352
-
-
Yang, L.1
Anderson, D.E.2
Baecher-Allan, C.3
-
46
-
-
3042720708
-
Thymic origin of intestinal alphabeta T cells revealed by fate mapping of RORgammat+ cells
-
Eberl G, Littman DR. Thymic origin of intestinal alphabeta T cells revealed by fate mapping of RORgammat+ cells. Science 2004 305 : 248 251.
-
(2004)
Science
, vol.305
, pp. 248-251
-
-
Eberl, G.1
Littman, D.R.2
-
47
-
-
0346496018
-
An essential function for the nuclear receptor RORgamma(t) in the generation of fetal lymphoid tissue inducer cells
-
Eberl G, Marmon S, Sunshine MJ, Rennert PD, Choi Y, Littman DR. An essential function for the nuclear receptor RORgamma(t) in the generation of fetal lymphoid tissue inducer cells. Nat Immunol 2004 5 : 64 73.
-
(2004)
Nat Immunol
, vol.5
, pp. 64-73
-
-
Eberl, G.1
Marmon, S.2
Sunshine, M.J.3
Rennert, P.D.4
Choi, Y.5
Littman, D.R.6
-
48
-
-
33748588423
-
The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17(+) T helper cells
-
Ivanov II, McKenzie BS, Zhou L et al. The Orphan Nuclear Receptor RORgammat Directs the Differentiation Program of Proinflammatory IL-17(+) T Helper Cells. Cell 2006 126 : 1121 1133.
-
(2006)
Cell
, vol.126
, pp. 1121-1133
-
-
Ivanov, I.I.1
McKenzie, B.S.2
Zhou, L.3
-
49
-
-
65349172388
-
Transcriptional regulatory networks in Th17 cell differentiation
-
Zhou L, Littman DR. Transcriptional regulatory networks in Th17 cell differentiation. Curr Opin Immunol 2009 21 : 146 152.
-
(2009)
Curr Opin Immunol
, vol.21
, pp. 146-152
-
-
Zhou, L.1
Littman, D.R.2
-
50
-
-
37849048599
-
T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma
-
Yang XO, Pappu BP, Nurieva R et al. T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma. Immunity 2008 28 : 29 39.
-
(2008)
Immunity
, vol.28
, pp. 29-39
-
-
Yang, X.O.1
Pappu, B.P.2
Nurieva, R.3
-
51
-
-
58449124804
-
The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells
-
Bauquet AT, Jin H, Paterson AM et al. The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells. Nat Immunol 2009 10 : 167 175.
-
(2009)
Nat Immunol
, vol.10
, pp. 167-175
-
-
Bauquet, A.T.1
Jin, H.2
Paterson, A.M.3
-
52
-
-
69249083836
-
Cutting edge: IL-27 induces the transcription factor c-Maf, cytokine IL-21, and the costimulatory receptor ICOS that coordinately act together to promote differentiation of IL-10-producing Tr1 cells
-
Pot C, Jin H, Awasthi A et al. Cutting edge: IL-27 induces the transcription factor c-Maf, cytokine IL-21, and the costimulatory receptor ICOS that coordinately act together to promote differentiation of IL-10-producing Tr1 cells. J Immunol 2009 183 : 797 801.
-
(2009)
J Immunol
, vol.183
, pp. 797-801
-
-
Pot, C.1
Jin, H.2
Awasthi, A.3
-
53
-
-
27544465354
-
A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17
-
Park H, Li Z, Yang XO et al. A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17. Nat Immunol 2005 6 : 1133 1141.
-
(2005)
Nat Immunol
, vol.6
, pp. 1133-1141
-
-
Park, H.1
Li, Z.2
Yang, X.O.3
-
54
-
-
27544490377
-
Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
-
Harrington LE, Hatton RD, Mangan PR et al. Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat Immunol 2005 6 : 1123 1132.
-
(2005)
Nat Immunol
, vol.6
, pp. 1123-1132
-
-
Harrington, L.E.1
Hatton, R.D.2
Mangan, P.R.3
-
55
-
-
33744479688
-
Selective regulatory function of Socs3 in the formation of IL-17-secreting T cells
-
Chen Z, Laurence A, Kanno Y et al. Selective regulatory function of Socs3 in the formation of IL-17-secreting T cells. Proc Natl Acad Sci U S A 2006 103 : 8137 8142.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 8137-8142
-
-
Chen, Z.1
Laurence, A.2
Kanno, Y.3
-
56
-
-
60749107176
-
The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17-producing effector T helper cells in vivo
-
McGeachy MJ, Chen Y, Tato CM et al. The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17-producing effector T helper cells in vivo. Nat Immunol 2009 10 : 314 324.
-
(2009)
Nat Immunol
, vol.10
, pp. 314-324
-
-
McGeachy, M.J.1
Chen, Y.2
Tato, C.M.3
-
57
-
-
68649090645
-
Cutting edge: IL-23 receptor gfp reporter mice reveal distinct populations of IL-17-producing cells
-
Awasthi A, Riol-Blanco L, Jäger A et al. Cutting edge: IL-23 receptor gfp reporter mice reveal distinct populations of IL-17-producing cells. J Immunol 2009 182 : 5904 5908.
-
(2009)
J Immunol
, vol.182
, pp. 5904-5908
-
-
Awasthi, A.1
Riol-Blanco, L.2
Jäger, A.3
-
58
-
-
63449127321
-
Prostaglandin E2 regulates Th17 cell differentiation and function through cyclic AMP and EP2/EP4 receptor signaling
-
Boniface K, Bak-Jensen KS, Li Y et al. Prostaglandin E2 regulates Th17 cell differentiation and function through cyclic AMP and EP2/EP4 receptor signaling. J Exp Med 2009 206 : 535 548.
-
(2009)
J Exp Med
, vol.206
, pp. 535-548
-
-
Boniface, K.1
Bak-Jensen, K.S.2
Li, Y.3
-
59
-
-
0036604306
-
A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rbeta1 and a novel cytokine receptor subunit, IL-23R
-
Parham C, Chirica M, Timans J et al. A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rbeta1 and a novel cytokine receptor subunit, IL-23R. J Immunol 2002 168 : 5699 5708.
-
(2002)
J Immunol
, vol.168
, pp. 5699-5708
-
-
Parham, C.1
Chirica, M.2
Timans, J.3
-
60
-
-
33749318470
-
Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides
-
Liang SC, Tan XY, Luxenberg DP et al. Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides. J Exp Med 2006 203 : 2271 2279.
-
(2006)
J Exp Med
, vol.203
, pp. 2271-2279
-
-
Liang, S.C.1
Tan, X.Y.2
Luxenberg, D.P.3
-
61
-
-
33846906224
-
Interleukin-22, a T(H)17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis
-
Zheng Y, Danilenko DM, Valdez P et al. Interleukin-22, a T(H)17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis. Nature 2007 445 : 648 651.
-
(2007)
Nature
, vol.445
, pp. 648-651
-
-
Zheng, Y.1
Danilenko, D.M.2
Valdez, P.3
-
63
-
-
76249117009
-
Crucial role of interleukin-7 in T helper type 17 survival and expansion in autoimmune disease
-
Liu X, Leung S, Wang C et al. Crucial role of interleukin-7 in T helper type 17 survival and expansion in autoimmune disease. Nat Med 2010 16 : 191 197.
-
(2010)
Nat Med
, vol.16
, pp. 191-197
-
-
Liu, X.1
Leung, S.2
Wang, C.3
-
64
-
-
43449135305
-
TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function
-
Zhou L, Lopes JE, Chong MM et al. TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function. Nature 2008 453 : 236 240.
-
(2008)
Nature
, vol.453
, pp. 236-240
-
-
Zhou, L.1
Lopes, J.E.2
Chong, M.M.3
-
65
-
-
44449131480
-
Isoform-specific inhibition of ROR alpha-mediated transcriptional activation by human FOXP3
-
Du J, Huang C, Zhou B, Ziegler SF. Isoform-specific inhibition of ROR alpha-mediated transcriptional activation by human FOXP3. J Immunol 2008 180 : 4785 4792.
-
(2008)
J Immunol
, vol.180
, pp. 4785-4792
-
-
Du, J.1
Huang, C.2
Zhou, B.3
Ziegler, S.F.4
-
66
-
-
33947162110
-
Interleukin-2 signaling via STAT5 constrains T helper 17 cell generation
-
Laurence A, Tato CM, Davidson TS et al. Interleukin-2 signaling via STAT5 constrains T helper 17 cell generation. Immunity 2007 26 : 371 381.
-
(2007)
Immunity
, vol.26
, pp. 371-381
-
-
Laurence, A.1
Tato, C.M.2
Davidson, T.S.3
-
67
-
-
34447503805
-
Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid
-
Mucida D, Park Y, Kim G et al. Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid. Science 2007 317 : 256 260.
-
(2007)
Science
, vol.317
, pp. 256-260
-
-
Mucida, D.1
Park, Y.2
Kim, G.3
-
68
-
-
42649106556
-
The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins
-
Veldhoen M, Hirota K, Westendorf AM et al. The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins. Nature 2008 453 : 106 109.
-
(2008)
Nature
, vol.453
, pp. 106-109
-
-
Veldhoen, M.1
Hirota, K.2
Westendorf, A.M.3
-
69
-
-
42649095378
-
Control of T(reg) and T(H)17 cell differentiation by the aryl hydrocarbon receptor
-
Quintana FJ, Basso AS, Iglesias AH et al. Control of T(reg) and T(H)17 cell differentiation by the aryl hydrocarbon receptor. Nature 2008 453 : 65 71.
-
(2008)
Nature
, vol.453
, pp. 65-71
-
-
Quintana, F.J.1
Basso, A.S.2
Iglesias, A.H.3
-
70
-
-
56149125346
-
Cutting edge: Th1 cells facilitate the entry of Th17 cells to the central nervous system during experimental autoimmune encephalomyelitis
-
O'Connor RA, Prendergast CT, Sabatos CA et al. Cutting edge: Th1 cells facilitate the entry of Th17 cells to the central nervous system during experimental autoimmune encephalomyelitis. J Immunol 2008 181 : 3750 3754.
-
(2008)
J Immunol
, vol.181
, pp. 3750-3754
-
-
O'Connor, R.A.1
Prendergast, C.T.2
Sabatos, C.A.3
-
71
-
-
34147128572
-
Myelin-specific regulatory T cells accumulate in the CNS but fail to control autoimmune inflammation
-
Korn T, Reddy J, Gao W et al. Myelin-specific regulatory T cells accumulate in the CNS but fail to control autoimmune inflammation. Nat Med 2007 13 : 423 431.
-
(2007)
Nat Med
, vol.13
, pp. 423-431
-
-
Korn, T.1
Reddy, J.2
Gao, W.3
-
72
-
-
34248562792
-
IL-23 and IL-17 in the establishment of protective pulmonary CD4+ T cell responses after vaccination and during Mycobacterium tuberculosis challenge
-
Khader SA, Bell GK, Pearl JE et al. IL-23 and IL-17 in the establishment of protective pulmonary CD4+ T cell responses after vaccination and during Mycobacterium tuberculosis challenge. Nat Immunol 2007 8 : 369 377.
-
(2007)
Nat Immunol
, vol.8
, pp. 369-377
-
-
Khader, S.A.1
Bell, G.K.2
Pearl, J.E.3
-
73
-
-
0032519405
-
The chemokine receptors CXCR3 and CCR5 mark subsets of T cells associated with certain inflammatory reactions
-
Qin S, Rottman JB, Myers P et al. The chemokine receptors CXCR3 and CCR5 mark subsets of T cells associated with certain inflammatory reactions. J Clin Invest 1998 101 : 746 754.
-
(1998)
J Clin Invest
, vol.101
, pp. 746-754
-
-
Qin, S.1
Rottman, J.B.2
Myers, P.3
-
74
-
-
36549019912
-
Preferential recruitment of CCR6-expressing Th17 cells to inflamed joints via CCL20 in rheumatoid arthritis and its animal model
-
Hirota K, Yoshitomi H, Hashimoto M et al. Preferential recruitment of CCR6-expressing Th17 cells to inflamed joints via CCL20 in rheumatoid arthritis and its animal model. J Exp Med 2007 204 : 2803 2812.
-
(2007)
J Exp Med
, vol.204
, pp. 2803-2812
-
-
Hirota, K.1
Yoshitomi, H.2
Hashimoto, M.3
-
75
-
-
58149216715
-
Th memory for interleukin-17 expression is stable in vivo
-
Lexberg MH, Taubner A, Forster A et al. Th memory for interleukin-17 expression is stable in vivo. Eur J Immunol 2008 38 : 2654 2664.
-
(2008)
Eur J Immunol
, vol.38
, pp. 2654-2664
-
-
Lexberg, M.H.1
Taubner, A.2
Forster, A.3
-
76
-
-
58149190437
-
Phenotype switching by inflammation-inducing polarized Th17 cells, but not by Th1 cells
-
Shi G, Cox CA, Vistica BP, Tan C, Wawrousek EF, Gery I. Phenotype switching by inflammation-inducing polarized Th17 cells, but not by Th1 cells. J Immunol 2008 181 : 7205 7213.
-
(2008)
J Immunol
, vol.181
, pp. 7205-7213
-
-
Shi, G.1
Cox, C.A.2
Vistica, B.P.3
Tan, C.4
Wawrousek, E.F.5
Gery, I.6
-
77
-
-
67650650890
-
Highly purified Th17 cells from BDC2.5NOD mice convert into Th1-like cells in NOD/SCID recipient mice
-
Bending D, De La Pena H, Veldhoen M et al. Highly purified Th17 cells from BDC2.5NOD mice convert into Th1-like cells in NOD/SCID recipient mice. J Clin Invest 2009 119 : 565 572.
-
(2009)
J Clin Invest
, vol.119
, pp. 565-572
-
-
Bending, D.1
De La Pena, H.2
Veldhoen, M.3
-
78
-
-
58149251898
-
Late developmental plasticity in the T helper 17 lineage
-
Lee YK, Turner H, Maynard CL et al. Late developmental plasticity in the T helper 17 lineage. Immunity 2009 30 : 92 107.
-
(2009)
Immunity
, vol.30
, pp. 92-107
-
-
Lee, Y.K.1
Turner, H.2
Maynard, C.L.3
-
79
-
-
42249084849
-
Either a Th17 or a Th1 effector response can drive autoimmunity: Conditions of disease induction affect dominant effector category
-
Luger D, Silver PB, Tang J et al. Either a Th17 or a Th1 effector response can drive autoimmunity: conditions of disease induction affect dominant effector category. J Exp Med 2008 205 : 799 810.
-
(2008)
J Exp Med
, vol.205
, pp. 799-810
-
-
Luger, D.1
Silver, P.B.2
Tang, J.3
-
80
-
-
58149159798
-
Regional CNS responses to IFN-gamma determine lesion localization patterns during EAE pathogenesis
-
Lees JR, Golumbek PT, Sim J, Dorsey D, Russell JH. Regional CNS responses to IFN-gamma determine lesion localization patterns during EAE pathogenesis. J Exp Med 2008 205 : 2633 2642.
-
(2008)
J Exp Med
, vol.205
, pp. 2633-2642
-
-
Lees, J.R.1
Golumbek, P.T.2
Sim, J.3
Dorsey, D.4
Russell, J.H.5
-
81
-
-
40449089827
-
Differential regulation of central nervous system autoimmunity by T(H)1 and T(H)17 cells
-
Stromnes IM, Cerretti LM, Liggitt D, Harris RA, Goverman JM. Differential regulation of central nervous system autoimmunity by T(H)1 and T(H)17 cells. Nat Med 2008 14 : 337 342.
-
(2008)
Nat Med
, vol.14
, pp. 337-342
-
-
Stromnes, I.M.1
Cerretti, L.M.2
Liggitt, D.3
Harris, R.A.4
Goverman, J.M.5
-
82
-
-
2442708947
-
Detection of ectopic B-cell follicles with germinal centers in the meninges of patients with secondary progressive multiple sclerosis
-
Serafini B, Rosicarelli B, Magliozzi R, Stigliano E, Aloisi F. Detection of ectopic B-cell follicles with germinal centers in the meninges of patients with secondary progressive multiple sclerosis. Brain Pathol 2004 14 : 164 174.
-
(2004)
Brain Pathol
, vol.14
, pp. 164-174
-
-
Serafini, B.1
Rosicarelli, B.2
Magliozzi, R.3
Stigliano, E.4
Aloisi, F.5
-
83
-
-
42649134105
-
Interleukin-21: Basic biology and implications for cancer and autoimmunity
-
Spolski R, Leonard WJ. Interleukin-21: basic biology and implications for cancer and autoimmunity. Annu Rev Immunol 2008 26 : 57 79.
-
(2008)
Annu Rev Immunol
, vol.26
, pp. 57-79
-
-
Spolski, R.1
Leonard, W.J.2
-
84
-
-
46749151286
-
Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages
-
Nurieva RI, Chung Y, Hwang D et al. Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages. Immunity 2008 29 : 138 149.
-
(2008)
Immunity
, vol.29
, pp. 138-149
-
-
Nurieva, R.I.1
Chung, Y.2
Hwang, D.3
-
85
-
-
46949104323
-
IL-12- and IL-23-modulated T cells induce distinct types of EAE based on histology, CNS chemokine profile, and response to cytokine inhibition
-
Kroenke MA, Carlson TJ, Andjelkovic AV, Segal BM. IL-12- and IL-23-modulated T cells induce distinct types of EAE based on histology, CNS chemokine profile, and response to cytokine inhibition. J Exp Med 2008 205 : 1535 1541.
-
(2008)
J Exp Med
, vol.205
, pp. 1535-1541
-
-
Kroenke, M.A.1
Carlson, T.J.2
Andjelkovic, A.V.3
Segal, B.M.4
-
86
-
-
52049111828
-
How interferon-gamma keeps autoimmune diseases in check
-
Kelchtermans H, Billiau A, Matthys P. How interferon-gamma keeps autoimmune diseases in check. Trends Immunol 2008 29 : 479 486.
-
(2008)
Trends Immunol
, vol.29
, pp. 479-486
-
-
Kelchtermans, H.1
Billiau, A.2
Matthys, P.3
-
87
-
-
77950534540
-
T helper type 1 and 17 cells determine efficacy of interferon-beta in multiple sclerosis and experimental encephalomyelitis
-
Axtell RC, de Jong BA, Boniface K et al. T helper type 1 and 17 cells determine efficacy of interferon-beta in multiple sclerosis and experimental encephalomyelitis. Nat Med 2010 16 : 406 412.
-
(2010)
Nat Med
, vol.16
, pp. 406-412
-
-
Axtell, R.C.1
De Jong, B.A.2
Boniface, K.3
-
88
-
-
34248572345
-
T(H)-17 cells in the circle of immunity and autoimmunity
-
Bettelli E, Oukka M, Kuchroo VK. T(H)-17 cells in the circle of immunity and autoimmunity. Nat Immunol 2007 8 : 345 350.
-
(2007)
Nat Immunol
, vol.8
, pp. 345-350
-
-
Bettelli, E.1
Oukka, M.2
Kuchroo, V.K.3
-
89
-
-
56349093347
-
IL-4 inhibits TGF-beta-induced Foxp3+ T cells and, together with TGF-beta, generates IL-9+ IL-10+ Foxp3(-) effector T cells
-
Dardalhon V, Awasthi A, Kwon H et al. IL-4 inhibits TGF-beta-induced Foxp3+ T cells and, together with TGF-beta, generates IL-9+ IL-10+ Foxp3(-) effector T cells. Nat Immunol 2008 9 : 1347 1355.
-
(2008)
Nat Immunol
, vol.9
, pp. 1347-1355
-
-
Dardalhon, V.1
Awasthi, A.2
Kwon, H.3
-
90
-
-
56349154943
-
Transforming growth factor-beta 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9-producing subset
-
Veldhoen M, Uyttenhove C, van Snick J et al. Transforming growth factor-beta 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9-producing subset. Nat Immunol 2008 9 : 1341 1346.
-
(2008)
Nat Immunol
, vol.9
, pp. 1341-1346
-
-
Veldhoen, M.1
Uyttenhove, C.2
Van Snick, J.3
-
91
-
-
0030667854
-
Interleukin-9 is involved in host protective immunity to intestinal nematode infection
-
DOI 10.1002/eji.1830271011
-
Faulkner H, Humphreys N, Renauld JC, Van Snick J, Grencis R. Interleukin-9 is involved in host protective immunity to intestinal nematode infection. Eur J Immunol 1997 27 : 2536 2540. (Pubitemid 27453841)
-
(1997)
European Journal of Immunology
, vol.27
, Issue.10
, pp. 2536-2540
-
-
Faulkner, H.1
Humphreys, N.2
Renauld, J.-C.3
Van Snick, J.4
Grencis, R.5
-
92
-
-
67650502393
-
Th9 and allergic disease
-
Soroosh P, Doherty TA. Th9 and allergic disease. Immunology 2009 127 : 450 458.
-
(2009)
Immunology
, vol.127
, pp. 450-458
-
-
Soroosh, P.1
Doherty, T.A.2
-
93
-
-
76949102494
-
Regulation of IL-9 expression by IL-25 signaling
-
Angkasekwinai P, Chang SH, Thapa M, Watarai H, Dong C. Regulation of IL-9 expression by IL-25 signaling. Nat Immunol 2010 11 : 250 256.
-
(2010)
Nat Immunol
, vol.11
, pp. 250-256
-
-
Angkasekwinai, P.1
Chang, S.H.2
Thapa, M.3
Watarai, H.4
Dong, C.5
-
94
-
-
0032700856
-
Allergen-induced IL-9 directly stimulates mucin transcription in respiratory epithelial cells
-
Longphre M, Li D, Gallup M et al. Allergen-induced IL-9 directly stimulates mucin transcription in respiratory epithelial cells. J Clin Invest 1999 104 : 1375 1382.
-
(1999)
J Clin Invest
, vol.104
, pp. 1375-1382
-
-
Longphre, M.1
Li, D.2
Gallup, M.3
-
95
-
-
52149102045
-
IL-9/IL-9 receptor signaling selectively protects cortical neurons against developmental apoptosis
-
Fontaine RH, Cases O, Lelievre V et al. IL-9/IL-9 receptor signaling selectively protects cortical neurons against developmental apoptosis. Cell Death Differ 2008 15 : 1542 1552.
-
(2008)
Cell Death Differ
, vol.15
, pp. 1542-1552
-
-
Fontaine, R.H.1
Cases, O.2
Lelievre, V.3
-
96
-
-
69149107148
-
IL-9 induces differentiation of TH17 cells and enhances function of FoxP3+ natural regulatory T cells
-
Elyaman W, Bradshaw EM, Uyttenhove C et al. IL-9 induces differentiation of TH17 cells and enhances function of FoxP3+ natural regulatory T cells. Proc Natl Acad Sci U S A 2009 106 : 12885 12890.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 12885-12890
-
-
Elyaman, W.1
Bradshaw, E.M.2
Uyttenhove, C.3
-
97
-
-
68149179251
-
IL-9 as a mediator of Th17-driven inflammatory disease
-
Nowak EC, Weaver CT, Turner H et al. IL-9 as a mediator of Th17-driven inflammatory disease. J Exp Med 2009 206 : 1653 1660.
-
(2009)
J Exp Med
, vol.206
, pp. 1653-1660
-
-
Nowak, E.C.1
Weaver, C.T.2
Turner, H.3
-
98
-
-
0034610971
-
Mast cells are essential for early onset and severe disease in a murine model of multiple sclerosis
-
Secor VH, Secor WE, Gutekunst CA, Brown MA. Mast cells are essential for early onset and severe disease in a murine model of multiple sclerosis. J Exp Med 2000 191 : 813 822.
-
(2000)
J Exp Med
, vol.191
, pp. 813-822
-
-
Secor, V.H.1
Secor, W.E.2
Gutekunst, C.A.3
Brown, M.A.4
-
99
-
-
0023879370
-
The role of mast cells in demyelination. 1. Myelin proteins are degraded by mast cell proteases and myelin basic protein and P2 can stimulate mast cell degranulation
-
Johnson D, Seeldrayers PA, Weiner HL. The role of mast cells in demyelination. 1. Myelin proteins are degraded by mast cell proteases and myelin basic protein and P2 can stimulate mast cell degranulation. Brain Res 1988 444 : 195 198.
-
(1988)
Brain Res
, vol.444
, pp. 195-198
-
-
Johnson, D.1
Seeldrayers, P.A.2
Weiner, H.L.3
-
100
-
-
0035952643
-
Protease activated receptors: Theme and variations
-
O'Brien PJ, Molino M, Kahn M, Brass LF. Protease activated receptors: theme and variations. Oncogene 2001 20 : 1570 1581.
-
(2001)
Oncogene
, vol.20
, pp. 1570-1581
-
-
O'Brien, P.J.1
Molino, M.2
Kahn, M.3
Brass, L.F.4
-
101
-
-
0035162560
-
Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse
-
Brunkow ME, Jeffery EW, Hjerrild KA et al. Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse. Nat Genet 2001 27 : 68 73.
-
(2001)
Nat Genet
, vol.27
, pp. 68-73
-
-
Brunkow, M.E.1
Jeffery, E.W.2
Hjerrild, K.A.3
-
102
-
-
0035675798
-
IPEX is a unique X-linked syndrome characterized by immune dysfunction, polyendocrinopathy, enteropathy, and a variety of autoimmune phenomena
-
Bennett CL, Ochs HD. IPEX is a unique X-linked syndrome characterized by immune dysfunction, polyendocrinopathy, enteropathy, and a variety of autoimmune phenomena. Curr Opin Pediatr 2001 13 : 533 538.
-
(2001)
Curr Opin Pediatr
, vol.13
, pp. 533-538
-
-
Bennett, C.L.1
Ochs, H.D.2
-
104
-
-
46749138596
-
Molecular antagonism and plasticity of regulatory and inflammatory T cell programs
-
Yang XO, Nurieva R, Martinez GJ et al. Molecular antagonism and plasticity of regulatory and inflammatory T cell programs. Immunity 2008 29 : 44 56.
-
(2008)
Immunity
, vol.29
, pp. 44-56
-
-
Yang, X.O.1
Nurieva, R.2
Martinez, G.J.3
-
105
-
-
45149109643
-
In vivo equilibrium of proinflammatory IL-17+ and regulatory IL-10+ Foxp3+ RORgamma t+ T cells
-
Lochner M, Peduto L, Cherrier M et al. In vivo equilibrium of proinflammatory IL-17+ and regulatory IL-10+ Foxp3+ RORgamma t+ T cells. J Exp Med 2008 205 : 1381 1393.
-
(2008)
J Exp Med
, vol.205
, pp. 1381-1393
-
-
Lochner, M.1
Peduto, L.2
Cherrier, M.3
-
106
-
-
63849183918
-
Identification of IL-17-producing FOXP3+ regulatory T cells in humans
-
Voo KS, Wang YH, Santori FR et al. Identification of IL-17-producing FOXP3+ regulatory T cells in humans. Proc Natl Acad Sci U S A 2009 106 : 4793 4798.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 4793-4798
-
-
Voo, K.S.1
Wang, Y.H.2
Santori, F.R.3
-
107
-
-
70449532980
-
Decrease of Foxp3+ Treg cell number and acquisition of effector cell phenotype during lethal infection
-
Oldenhove G, Bouladoux N, Wohlfert EA et al. Decrease of Foxp3+ Treg cell number and acquisition of effector cell phenotype during lethal infection. Immunity 2009 31 : 772 786.
-
(2009)
Immunity
, vol.31
, pp. 772-786
-
-
Oldenhove, G.1
Bouladoux, N.2
Wohlfert, E.A.3
-
108
-
-
69049107358
-
Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo
-
Zhou X, Bailey-Bucktrout SL, Jeker LT et al. Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo. Nat Immunol 2009 10 : 1000 1007.
-
(2009)
Nat Immunol
, vol.10
, pp. 1000-1007
-
-
Zhou, X.1
Bailey-Bucktrout, S.L.2
Jeker, L.T.3
-
109
-
-
36248970701
-
A dominant function for interleukin 27 in generating interleukin 10-producing anti-inflammatory T cells
-
Awasthi A, Carrier Y, Peron JP et al. A dominant function for interleukin 27 in generating interleukin 10-producing anti-inflammatory T cells. Nat Immunol 2007 8 : 1380 1389.
-
(2007)
Nat Immunol
, vol.8
, pp. 1380-1389
-
-
Awasthi, A.1
Carrier, Y.2
Peron, J.P.3
-
110
-
-
36248951161
-
Interleukins 27 and 6 induce STAT3-mediated T cell production of interleukin 10
-
Stumhofer JS, Silver JS, Laurence A et al. Interleukins 27 and 6 induce STAT3-mediated T cell production of interleukin 10. Nat Immunol 2007 8 : 1363 1371.
-
(2007)
Nat Immunol
, vol.8
, pp. 1363-1371
-
-
Stumhofer, J.S.1
Silver, J.S.2
Laurence, A.3
-
111
-
-
36248970702
-
Suppression of autoimmune inflammation of the central nervous system by interleukin 10 secreted by interleukin 27-stimulated T cells
-
Fitzgerald DC, Zhang GX, El-Behi M et al. Suppression of autoimmune inflammation of the central nervous system by interleukin 10 secreted by interleukin 27-stimulated T cells. Nat Immunol 2007 8 : 1372 1379.
-
(2007)
Nat Immunol
, vol.8
, pp. 1372-1379
-
-
Fitzgerald, D.C.1
Zhang, G.X.2
El-Behi, M.3
-
112
-
-
2442450433
-
IL-10-secreting regulatory T cells do not express Foxp3 but have comparable regulatory function to naturally occurring CD4+CD25+ regulatory T cells
-
Vieira PL, Christensen JR, Minaee S et al. IL-10-secreting regulatory T cells do not express Foxp3 but have comparable regulatory function to naturally occurring CD4+CD25+ regulatory T cells. J Immunol 2004 172 : 5986 5993.
-
(2004)
J Immunol
, vol.172
, pp. 5986-5993
-
-
Vieira, P.L.1
Christensen, J.R.2
Minaee, S.3
-
113
-
-
33747588291
-
Interleukin 27 limits autoimmune encephalomyelitis by suppressing the development of interleukin 17-producing T cells
-
Batten M, Li J, Yi S et al. Interleukin 27 limits autoimmune encephalomyelitis by suppressing the development of interleukin 17-producing T cells. Nat Immunol 2006 7 : 929 936.
-
(2006)
Nat Immunol
, vol.7
, pp. 929-936
-
-
Batten, M.1
Li, J.2
Yi, S.3
-
114
-
-
77449132554
-
Antigen-specific dependence of Tr1-cell therapy in preclinical models of islet transplant
-
Gagliani N, Jofra T, Stabilini A et al. Antigen-specific dependence of Tr1-cell therapy in preclinical models of islet transplant. Diabetes 2010 59 : 433 439.
-
(2010)
Diabetes
, vol.59
, pp. 433-439
-
-
Gagliani, N.1
Jofra, T.2
Stabilini, A.3
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