-
1
-
-
0033838364
-
Iron-dependent self assembly of recombinant yeast frataxin: Implications for Friedreich ataxia
-
Adamec J, Rusnak F, Owen WG, Naylor S, Benson LM, Gacy AM, and Isaya G. Iron-dependent self assembly of recombinant yeast frataxin: implications for Friedreich ataxia. Am J Hum Genet 67: 549-562, 2000.
-
(2000)
Am J Hum Genet
, vol.67
, pp. 549-562
-
-
Adamec, J.1
Rusnak, F.2
Owen, W.G.3
Naylor, S.4
Benson, L.M.5
Gacy, A.M.6
Isaya, G.7
-
2
-
-
64049116040
-
Bacterial frataxin CyaY is the gatekeeper of iron-sulfur cluster formation catalyzed by IscS
-
Adinolfi S, Iannuzzi C, Prischi F, Pastore C, Iametti S, Martin SR, Bonomi F, and Pastore A. Bacterial frataxin CyaY is the gatekeeper of iron-sulfur cluster formation catalyzed by IscS. Nat Struct Mol Biol 16: 390-396, 2009.
-
(2009)
Nat Struct Mol Biol
, vol.16
, pp. 390-396
-
-
Adinolfi, S.1
Iannuzzi, C.2
Prischi, F.3
Pastore, C.4
Iametti, S.5
Martin, S.R.6
Bonomi, F.7
Pastore, A.8
-
3
-
-
0036667986
-
A structural approach to understanding the ironbinding properties of phylogenetically different frataxins
-
Adinolfi S, Trifuoggi M, Politou AS, Martin S, and Pastore A. A structural approach to understanding the ironbinding properties of phylogenetically different frataxins. Hum Mol Genet 11: 1865-1877, 2002.
-
(2002)
Hum Mol Genet 11
, pp. 1865-1877
-
-
Adinolfi, S.1
Trifuoggi, M.2
Politou, A.S.3
Martin, S.4
Pastore, A.5
-
4
-
-
0038312385
-
Decreased liver hepcidin expression in the Hfe knockout mouse
-
Ahmad KA, Ahmann JR, Migas MC, Waheed A, Britton RS, Bacon BR, Sly WS, and Fleming RE. Decreased liver hepcidin expression in the Hfe knockout mouse. Blood Cells Mol Dis 29: 361-366, 2002.
-
(2002)
Blood Cells Mol Dis
, vol.29
, pp. 361-366
-
-
Ahmad, K.A.1
Ahmann, J.R.2
Migas, M.C.3
Waheed, A.4
Britton, R.S.5
Bacon, B.R.6
Sly, W.S.7
Fleming, R.E.8
-
5
-
-
0032920837
-
Mutation of a putative mitochondrial iron transporter gene (ABC7). in X-linked sideroblastic anemia and ataxia (XLSA/A)
-
Allikmets R, Raskind WH, Hutchinson A, Schueck ND, Dean M, and Koeller DM. Mutation of a putative mitochondrial iron transporter gene (ABC7) in X-linked sideroblastic anemia and ataxia (XLSA/A). Hum Mol Genet 8: 743-749, 1999.
-
(1999)
Hum Mol Genet
, vol.8
, pp. 743-749
-
-
Allikmets, R.1
Raskind, W.H.2
Hutchinson, A.3
Schueck, N.D.4
Dean, M.5
Koeller, D.M.6
-
6
-
-
9644279682
-
Iron-induced oligomerization of yeast frataxin homologue Yfh1 is dispensable in vivo
-
Aloria K, Schilke B, Andrew A, and Craig EA. Iron-induced oligomerization of yeast frataxin homologue Yfh1 is dispensable in vivo. EMBO Rep 5: 1096-1101, 2004.
-
(2004)
EMBO Rep
, vol.5
, pp. 1096-1101
-
-
Aloria, K.1
Schilke, B.2
Andrew, A.3
Craig, E.A.4
-
8
-
-
0035672913
-
X-linked cerebellar ataxia and sideroblastic anaemia associated with a missense mutation in the ABC7 gene predicting V411L
-
Andrew M, Kate H, Simon H, and Alison M. X-linked cerebellar ataxia and sideroblastic anaemia associated with a missense mutation in the ABC7 gene predicting V411L. Br J Haematol 115: 910-917, 2001.
-
(2001)
Br J Haematol
, vol.115
, pp. 910-917
-
-
Andrew, M.1
Kate, H.2
Simon, H.3
Alison, M.4
-
9
-
-
70349500209
-
ABCs of erythroid mitochondrial iron uptake
-
Andrews NC. ABCs of erythroid mitochondrial iron uptake. Proc Natl Acad Sci U S A 106: 16012-16013, 2009.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 16012-16013
-
-
Andrews, N.C.1
-
10
-
-
67349100157
-
Ferritins: A family of molecules for iron storage, antioxidation and more
-
Arosio P, Ingrassia R, and Cavadini P. Ferritins: a family of molecules for iron storage, antioxidation and more. Biochim Biophys Acta 1790: 589-599, 2009.
-
(2009)
Biochim Biophys Acta
, vol.1790
, pp. 589-599
-
-
Arosio, P.1
Ingrassia, R.2
Cavadini, P.3
-
11
-
-
0030846021
-
Regulation of mitochondrial iron accumulation by Yfh1p, a putative homolog of frataxin
-
Babcock M, de Silva D, Oaks R, Davis-Kaplan S, Jiralerspong S, Montermini L, Pandolfo M, and Kaplan J. Regulation of mitochondrial iron accumulation by Yfh1p, a putative homolog of frataxin. Science 276: 1709-1712, 1997.
-
(1997)
Science
, vol.276
, pp. 1709-1712
-
-
Babcock, M.1
De Silva, D.2
Oaks, R.3
Davis-Kaplan, S.4
Jiralerspong, S.5
Montermini, L.6
Pandolfo, M.7
Kaplan, J.8
-
12
-
-
0035122450
-
Frataxin: Its role in iron metabolism and the pathogenesis of Friedreich's ataxia
-
Becker E and Richardson DR. Frataxin: its role in iron metabolism and the pathogenesis of Friedreich's ataxia. Int J Biochem Cell Biol 33: 1-10, 2001.
-
(2001)
Int J Biochem Cell Biol
, vol.33
, pp. 1-10
-
-
Becker, E.1
Richardson, D.R.2
-
13
-
-
0037093206
-
Erythroid differentiation and protoporphyrin IX downregulate frataxin expression in Friend cells: Characterization of frataxin expression compared to molecules involved in iron metabolism and hemoglobinization
-
Becker EM, Greer JM, Ponka P, and Richardson DR. Erythroid differentiation and protoporphyrin IX downregulate frataxin expression in Friend cells: characterization of frataxin expression compared to molecules involved in iron metabolism and hemoglobinization. Blood 99: 3813-3822, 2002.
-
(2002)
Blood
, vol.99
, pp. 3813-3822
-
-
Becker, E.M.1
Greer, J.M.2
Ponka, P.3
Richardson, D.R.4
-
14
-
-
0034329310
-
Human ABC7 transporter: Gene structure and mutation causing X-linked sideroblastic anemia with ataxia with disruption of cytosolic iron-sulfur protein maturation
-
Bekri S, Kispal G, Lange H, Fitzsimons E, Tolmie J, Lill R, and Bishop DF. Human ABC7 transporter: gene structure and mutation causing X-linked sideroblastic anemia with ataxia with disruption of cytosolic iron-sulfur protein maturation. Blood 96: 3256-3264, 2000.
-
(2000)
Blood
, vol.96
, pp. 3256-3264
-
-
Bekri, S.1
Kispal, G.2
Lange, H.3
Fitzsimons, E.4
Tolmie, J.5
Lill, R.6
Bishop, D.F.7
-
15
-
-
34247882804
-
Human frataxin: Iron and ferrochelatase binding surface
-
Bencze KZ, Yoon T, Millan-Pacheco C, Bradley PB, Pastor N, Cowan JA, and Stemmler TL. Human frataxin: iron and ferrochelatase binding surface. Chem Commun (18): 1798-1800, 2007.
-
(2007)
Chem Commun
, vol.18
, pp. 1798-1800
-
-
Bencze, K.Z.1
Yoon, T.2
Millan-Pacheco, C.3
Bradley, P.B.4
Pastor, N.5
Cowan, J.A.6
Stemmler, T.L.7
-
16
-
-
34347370842
-
Selective iron chelation in Friedreich ataxia: Biologic and clinical implications
-
Boddaert N, Sang K, Rotig A, Leroy-Willig A, Gallet S, Brunelle F, Sidi D, Thalabard JC, Munnich A, and Cabantchik ZI. Selective iron chelation in Friedreich ataxia: biologic and clinical implications. Blood 110: 401-408, 2007.
-
(2007)
Blood
, vol.110
, pp. 401-408
-
-
Boddaert, N.1
Sang, K.2
Rotig, A.3
Leroy-Willig, A.4
Gallet, S.5
Brunelle, F.6
Sidi, D.7
Thalabard, J.C.8
Munnich, A.9
Cabantchik, Z.I.10
-
17
-
-
0015893042
-
Study of intracellular iron distribution in rabbit reticulocytes with normal and inhibited heme synthesis
-
Borová J, Ponka P, and Neuwirt J. Study of intracellular iron distribution in rabbit reticulocytes with normal and inhibited heme synthesis. Biochim Biophys Acta 320: 143-156, 1973.
-
(1973)
Biochim Biophys Acta
, vol.320
, pp. 143-156
-
-
Borová, J.1
Ponka, P.2
Neuwirt, J.3
-
18
-
-
0037460697
-
Disrupted hepcidin regulation in HFEassociated haemochromatosis and the liver as a regulator of body iron homoeostasis
-
Bridle KR, Frazer DM, Wilkins SJ, Dixon JL, Purdie DM, Crawford DHG, Subramaniam VN, Powell LW, Anderson GJ, and Ramm GA. Disrupted hepcidin regulation in HFEassociated haemochromatosis and the liver as a regulator of body iron homoeostasis. Lancet 361: 669-673, 2003.
-
(2003)
Lancet
, vol.361
, pp. 669-673
-
-
Bridle, K.R.1
Frazer, D.M.2
Wilkins, S.J.3
Dixon, J.L.4
Purdie, D.M.5
Dhg, C.6
Subramaniam, V.N.7
Powell, L.W.8
Anderson, G.J.9
Ramm, G.A.10
-
19
-
-
3042763187
-
Frataxin acts as an iron chaperone protein to modulate mitochondrial aconitase activity
-
Bulteau A-L, O'Neill HA, Kennedy MC, Ikeda-Saito M, Isaya G, and Szweda LI. Frataxin acts as an iron chaperone protein to modulate mitochondrial aconitase activity. Science 305: 242-245, 2004.
-
(2004)
Science
, vol.305
, pp. 242-245
-
-
Bulteau, A.-L.1
O'Neill, H.A.2
Kennedy, M.C.3
Ikeda-Saito, M.4
Isaya, G.5
Szweda, L.I.6
-
20
-
-
34548013116
-
The human counterpart of zebrafish shiraz shows sideroblastic-like microcytic anemia and iron overload
-
Camaschella C, Campanella A, De Falco L, Boschetto L, Merlini R, Silvestri L, Levi S, and Iolascon A. The human counterpart of zebrafish shiraz shows sideroblastic-like microcytic anemia and iron overload. Blood 110: 1353-1358, 2007.
-
(2007)
Blood
, vol.110
, pp. 1353-1358
-
-
Camaschella, C.1
Campanella, A.2
De Falco, L.3
Boschetto, L.4
Merlini, R.5
Silvestri, L.6
Levi, S.7
Iolascon, A.8
-
21
-
-
5444262935
-
The expression of human mitochondrial ferritin rescues respiratory function in frataxin-deficient yeast
-
Campanella A, Isaya G, O'Neill HA, Santambrogio P, Cozzi A, Arosio P, and Levi S. The expression of human mitochondrial ferritin rescues respiratory function in frataxin-deficient yeast. Hum Mol Genet 13: 2279-2288, 2004.
-
(2004)
Hum Mol Genet
, vol.13
, pp. 2279-2288
-
-
Campanella, A.1
Isaya, G.2
O'Neill, H.A.3
Santambrogio, P.4
Cozzi, A.5
Arosio, P.6
Levi, S.7
-
22
-
-
9844222853
-
Frataxin is reduced in Friedreich ataxia patients and is associated with mitochondrial membranes
-
Campuzano V, Montermini L, Lutz Y, Cova L, Hindelang C, Jiralerspong S, Trottier Y, Kish SJ, Faucheux B, Trouillas P, Authier FJ, Durr A, Mandel JL, Vescovi A, Pandolfo M, and Koenig M. Frataxin is reduced in Friedreich ataxia patients and is associated with mitochondrial membranes. Hum Mol Genet 6: 1771-1780, 1997.
-
(1997)
Hum Mol Genet
, vol.6
, pp. 1771-1780
-
-
Campuzano, V.1
Montermini, L.2
Lutz, Y.3
Cova, L.4
Hindelang, C.5
Jiralerspong, S.6
Trottier, Y.7
Kish, S.J.8
Faucheux, B.9
Trouillas, P.10
Authier, F.J.11
Durr, A.12
Mandel, J.L.13
Vescovi, A.14
Pandolfo, M.15
Koenig, M.16
-
23
-
-
13344270899
-
Friedreich's ataxia: Autosomal recessive disease caused by an intronic GAA triplet repeat expansion
-
Campuzano V, Montermini L, Molto MD, Pianese L, Cossee M, Cavalcanti F, Monros E, Rodius F, Duclos F, Monticelli A, Zara F, Canizares J, Koutnikova H, Bidichandani SI, Gellera C, Brice A, Trouillas P, De Michele G, Filla A, De Frutos R, Palau F, Patel PI, Di Donato S, Mandel JL, Cocozza S, Koenig M, and Pandolfo M. Friedreich's ataxia: autosomal recessive disease caused by an intronic GAA triplet repeat expansion. Science 271: 1423-1427, 1996.
-
(1996)
Science
, vol.271
, pp. 1423-1427
-
-
Campuzano, V.1
Montermini, L.2
Molto, M.D.3
Pianese, L.4
Cossee, M.5
Cavalcanti, F.6
Monros, E.7
Rodius, F.8
Duclos, F.9
Monticelli, A.10
Zara, F.11
Canizares, J.12
Koutnikova, H.13
Bidichandani, S.I.14
Gellera, C.15
Brice, A.16
Trouillas, P.17
De Michele, G.18
Filla, A.19
De Frutos, R.20
Palau, F.21
Patel, P.I.22
Di Donato, S.23
Mandel, J.L.24
Cocozza, S.25
Koenig, M.26
Pandolfo, M.27
more..
-
24
-
-
0023882711
-
Iron-responsive elements-regulatory RNA sequences that control messenger-RNA levels and translation
-
Casey JL, Hentze MW, Koeller DM, Caughman SW, Rouault TA, Klausner RD, and Harford JB. Iron-responsive elements-regulatory RNA sequences that control messenger-RNA levels and translation. Science 240: 924-928, 1988.
-
(1988)
Science
, vol.240
, pp. 924-928
-
-
Casey, J.L.1
Hentze, M.W.2
Koeller, D.M.3
Caughman, S.W.4
Rouault, T.A.5
Klausner, R.D.6
Harford, J.B.7
-
25
-
-
0036472291
-
Assembly and iron-binding properties of human frataxin, the protein deficient in Friedreich ataxia
-
Cavadini P, O'Neill HA, Benada O, and Isaya G. Assembly and iron-binding properties of human frataxin, the protein deficient in Friedreich ataxia. Hum Mol Genet 11: 217-227, 2002.
-
(2002)
Hum Mol Genet
, vol.11
, pp. 217-227
-
-
Cavadini, P.1
O'Neill, H.A.2
Benada, O.3
Isaya, G.4
-
26
-
-
0037372442
-
Mitochondrial ferritin expression in erythroid cells from patients with sideroblastic anemia
-
Cazzola M, Invernizzi R, Bergamaschi G, Levi S, Corsi B, Travaglino E, Rolandi V, Biasiotto G, Drysdale J, and Arosio P. Mitochondrial ferritin expression in erythroid cells from patients with sideroblastic anemia. Blood 101: 1996-2000, 2003.
-
(2003)
Blood 101
, pp. 1996-2000
-
-
Cazzola, M.1
Invernizzi, R.2
Bergamaschi, G.3
Levi, S.4
Corsi, B.5
Travaglino, E.6
Rolandi, V.7
Biasiotto, G.8
Drysdale, J.9
Arosio, P.10
-
27
-
-
77956044833
-
Ferrochelatase forms an oligomeric complex with mitoferrin-1 and Abcb10 for erythroid heme biosynthesis
-
Chen W, Dailey HA, and Paw BH. Ferrochelatase forms an oligomeric complex with mitoferrin-1 and Abcb10 for erythroid heme biosynthesis. Blood 116: 628-630, 2010.
-
(2010)
Blood
, vol.116
, pp. 628-630
-
-
Chen, W.1
Dailey, H.A.2
Paw, B.H.3
-
28
-
-
70349479539
-
Abcb10 physically interacts with mitoferrin-1 (Slc25a37) to enhance its stability and function in the erythroid mitochondria
-
Chen W, Paradkar PN, Li L, Pierce EL, Langer NB, Takahashi-Makise N, Hyde BB, Shirihai OS, Ward DM, Kaplan J, and Paw BH. Abcb10 physically interacts with mitoferrin-1 (Slc25a37) to enhance its stability and function in the erythroid mitochondria. Proc Natl Acad Sci U S A 106: 16263-16268, 2009.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 16263-16268
-
-
Chen, W.1
Paradkar, P.N.2
Li, L.3
Pierce, E.L.4
Langer, N.B.5
Takahashi-Makise, N.6
Hyde, B.B.7
Shirihai, O.S.8
Ward, D.M.9
Kaplan, J.10
Paw, B.H.11
-
29
-
-
30944442611
-
A novel iron responsive element in the 3 UTR of human MRCK alpha
-
Cmejla R, Petrak J, and Cmejlova J. A novel iron responsive element in the 3 UTR of human MRCK alpha. Biochem Biophys Res Commun 341: 158-166, 2006.
-
(2006)
Biochem Biophys Res Commun
, vol.341
, pp. 158-166
-
-
Cmejla, R.1
Petrak, J.2
Cmejlova, J.3
-
30
-
-
77951621111
-
Human MRCK alpha is regulated by cellular iron levels and interferes with transferrin iron uptake
-
Cmejla R, Ptackova P, Petrak J, Savvulidi F, Cerny J, Sebesta O, and Vyoral D. Human MRCK alpha is regulated by cellular iron levels and interferes with transferrin iron uptake. Biochem Biophys Res Commun 395: 163-167, 2010.
-
(2010)
Biochem Biophys Res Commun
, vol.395
, pp. 163-167
-
-
Cmejla, R.1
Ptackova, P.2
Petrak, J.3
Savvulidi, F.4
Cerny, J.5
Sebesta, O.6
Vyoral, D.7
-
31
-
-
33746883937
-
Monomeric yeast frataxin is an iron-binding protein
-
Cook JD, Bencze KZ, Jankovic AD, Crater AK, Busch CN, Bradley PB, Stemmler AJ, Spaller MR, and Stemmler TL. Monomeric yeast frataxin is an iron-binding protein. Biochemistry 45: 7767-7777, 2006.
-
(2006)
Biochemistry
, vol.45
, pp. 7767-7777
-
-
Cook, J.D.1
Bencze, K.Z.2
Jankovic, A.D.3
Crater, A.K.4
Busch, C.N.5
Bradley, P.B.6
Stemmler, A.J.7
Spaller, M.R.8
Stemmler, T.L.9
-
32
-
-
0346158441
-
Friedreich's ataxia: Disease mechanisms, antioxidant and Coenzyme Q10 therapy
-
Cooper JM and Schapira AH. Friedreich's ataxia: disease mechanisms, antioxidant and Coenzyme Q10 therapy. Biofactors 18: 163-171, 2003.
-
(2003)
Biofactors
, vol.18
, pp. 163-171
-
-
Cooper, J.M.1
Schapira, A.H.2
-
33
-
-
23044503950
-
Microcytic anemia, erythropoietic protoporphyria, and neurodegeneration in mice with targeted deletion of iron-regulatory protein 2
-
Cooperman SS, Meyron-Holtz EG, Olivierre-Wilson H, Ghosh MC, McConnell JP, and Rouault TA. Microcytic anemia, erythropoietic protoporphyria, and neurodegeneration in mice with targeted deletion of iron-regulatory protein 2. Blood 106: 1084-1091, 2005.
-
(2005)
Blood
, vol.106
, pp. 1084-1091
-
-
Cooperman, S.S.1
Meyron-Holtz, E.G.2
Olivierre-Wilson, H.3
Ghosh, M.C.4
McConnell, J.P.5
Rouault, T.A.6
-
34
-
-
0037151089
-
Human mitochondrial ferritin expressed in HeLa cells incorporates iron and affects cellular iron metabolism
-
Corsi B, Cozzi A, Arosio P, Drysdale J, Santambrogio P, Campanella A, Biasiotto G, Albertini A, and Levi S. Human mitochondrial ferritin expressed in HeLa cells incorporates iron and affects cellular iron metabolism. J Biol Chem 277: 22430-22437, 2002.
-
(2002)
J Biol Chem
, vol.277
, pp. 22430-22437
-
-
Corsi, B.1
Cozzi, A.2
Arosio, P.3
Drysdale, J.4
Santambrogio, P.5
Campanella, A.6
Biasiotto, G.7
Albertini, A.8
Levi, S.9
-
35
-
-
0026603687
-
Enzymatic defect in X-linked sideroblastic anemia-molecular evidence for erythroid delta-aminolevulinate synthase deficiency
-
Cotter PD, Baumann M, and Bishop DF. Enzymatic defect in X-linked sideroblastic anemia-molecular evidence for erythroid delta-aminolevulinate synthase deficiency. Proc Natl Acad Sci U S A 89: 4028-4032, 1992.
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, pp. 4028-4032
-
-
Cotter, P.D.1
Baumann, M.2
Bishop, D.F.3
-
36
-
-
0025811624
-
Human erythroid 5-aminolevulinate synthase-promoter analysis and identification of an iron-responsive element in the messenger-RNA
-
Cox TC, Bawden MJ, Martin A, and May BK. Human erythroid 5-aminolevulinate synthase-promoter analysis and identification of an iron-responsive element in the messenger-RNA. EMBO J 10: 1891-1902, 1991.
-
(1991)
EMBO J
, vol.10
, pp. 1891-1902
-
-
Cox, T.C.1
Bawden, M.J.2
Martin, A.3
May, B.K.4
-
37
-
-
0032414310
-
Identification of a human mitochondrial ABC transporter, the functional orthologue of yeast Atm1p
-
Csere P, Lill R, and Kispal G. Identification of a human mitochondrial ABC transporter, the functional orthologue of yeast Atm1p. FEBS Lett 441: 266-270, 1998.
-
(1998)
FEBS Lett
, vol.441
, pp. 266-270
-
-
Csere, P.1
Lill, R.2
Kispal, G.3
-
39
-
-
0025822118
-
Identification of a novel iron-responsive element in murine and human erythroid delta-aminolevulinic-acid synthase messenger-RNA
-
Dandekar T, Stripecke R, Gray NK, Goossen B, Constable A, Johansson HE, and Hentze MW. Identification of a novel iron-responsive element in murine and human erythroid delta-aminolevulinic-acid synthase messenger-RNA. EMBO J 10: 1903-1909, 1991.
-
(1991)
EMBO J
, vol.10
, pp. 1903-1909
-
-
Dandekar, T.1
Stripecke, R.2
Gray, N.K.3
Goossen, B.4
Constable, A.5
Johansson, H.E.6
Hentze, M.W.7
-
40
-
-
0032533572
-
Cloning and characterization of Gallus and Xenopus ferrochelatases: Presence of the [2Fe-2S] cluster in nonmammalian ferrochelatase
-
Day AL, Parsons BM, and Dailey HA. Cloning and characterization of Gallus and Xenopus ferrochelatases: presence of the [2Fe-2S] cluster in nonmammalian ferrochelatase. Arch Biochem Biophys 359: 160-169, 1998.
-
(1998)
Arch Biochem Biophys
, vol.359
, pp. 160-169
-
-
Day, A.L.1
Parsons, B.M.2
Dailey, H.A.3
-
41
-
-
0034677467
-
Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter
-
Donovan A, Brownlie A, Zhou Y, Shepard J, Pratt SJ, Moynihan J, Paw BH, Drejer A, Barut B, Zapata A, Law TC, Brugnara C, Kingsley PD, Palis J, Fleming MD, Andrews NC, and Zon LI. Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter. Nature 403: 776-781, 2000.
-
(2000)
Nature
, vol.403
, pp. 776-781
-
-
Donovan, A.1
Brownlie, A.2
Zhou, Y.3
Shepard, J.4
Pratt, S.J.5
Moynihan, J.6
Paw, B.H.7
Drejer, A.8
Barut, B.9
Zapata, A.10
Law, T.C.11
Brugnara, C.12
Kingsley, P.D.13
Palis, J.14
Fleming, M.D.15
Andrews, N.C.16
Zon, L.I.17
-
42
-
-
20444416123
-
The iron exporter ferroportin/ Slc40a1 is essential for iron homeostasis
-
Donovan A, Lima CA, Pinkus JL, Pinkus GS, Zon LI, Robine S, and Andrews NC. The iron exporter ferroportin/ Slc40a1 is essential for iron homeostasis. Cell Metab 1: 191-200, 2005.
-
(2005)
Cell Metab
, vol.1
, pp. 191-200
-
-
Donovan, A.1
Lima, C.A.2
Pinkus, J.L.3
Pinkus, G.S.4
Zon, L.I.5
Robine, S.6
Andrews, N.C.7
-
43
-
-
0242422377
-
Mitochondrial ferritin: A new player in iron metabolism
-
Drysdale J, Arosio P, Invernizzi R, Cazzola M, Volz A, Corsi B, Biasiotto G, and Levi S. Mitochondrial ferritin: a new player in iron metabolism. Blood Cells Mol Dis 29: 376-383, 2002.
-
(2002)
Blood Cells Mol Dis
, vol.29
, pp. 376-383
-
-
Drysdale, J.1
Arosio, P.2
Invernizzi, R.3
Cazzola, M.4
Volz, A.5
Corsi, B.6
Biasiotto, G.7
Levi, S.8
-
45
-
-
0029821176
-
Clinical and genetic abnormalities in patients with Friedreich's ataxia
-
Durr A, Cossee M, Agid Y, Campuzano V, Mignard C, Penet C, Mandel JL, Brice A, and Koenig M. Clinical and genetic abnormalities in patients with Friedreich's ataxia. N Engl J Med 335: 1169-1175, 1996.
-
(1996)
N Engl J Med
, vol.335
, pp. 1169-1175
-
-
Durr, A.1
Cossee, M.2
Agid, Y.3
Campuzano, V.4
Mignard, C.5
Penet, C.6
Mandel, J.L.7
Brice, A.8
Koenig, M.9
-
46
-
-
0036569986
-
Molecular bases of cellular iron toxicity
-
Eaton JW and Qian M. Molecular bases of cellular iron toxicity. Free Radic Biol Med 32: 833-840, 2002.
-
(2002)
Free Radic Biol Med
, vol.32
, pp. 833-840
-
-
Eaton, J.W.1
Qian, M.2
-
47
-
-
0032477866
-
Nramp2 is mutated in the anemic Belgrade (b) rat: Evidence of a role for Nramp2 in endosomal iron transport
-
Fleming MD, Romano MA, Su MA, Garrick LM, Garrick MD, and Andrews NC. Nramp2 is mutated in the anemic Belgrade (b) rat: evidence of a role for Nramp2 in endosomal iron transport. Proc Natl Acad Sci U S A 95: 1148-1153, 1998.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 1148-1153
-
-
Fleming, M.D.1
Romano, M.A.2
Su, M.A.3
Garrick, L.M.4
Garrick, M.D.5
Andrews, N.C.6
-
48
-
-
0030763856
-
Microcytic anaemia mice have a mutation in Nramp2, a candidate iron transporter gene
-
Fleming MD, Trenor CC 3rd, Su MA, Foernzler D, Beier DR, Dietrich WF, and Andrews NC. Microcytic anaemia mice have a mutation in Nramp2, a candidate iron transporter gene. Nat Genet 16: 383-386, 1997.
-
(1997)
Nat Genet
, vol.16
, pp. 383-386
-
-
Fleming, M.D.1
Trenor III, C.C.2
Su, M.A.3
Foernzler, D.4
Beier, D.R.5
Dietrich, W.F.6
Andrews, N.C.7
-
49
-
-
0037025331
-
Deletion of the mitochondrial carrier genes MRS3 and MRS4 suppresses mitochondrial iron accumulation in a yeast frataxin-deficient strain
-
Foury F and Roganti T. Deletion of the mitochondrial carrier genes MRS3 and MRS4 suppresses mitochondrial iron accumulation in a yeast frataxin-deficient strain. J Biol Chem 277: 24475-24483, 2002.
-
(2002)
J Biol Chem
, vol.277
, pp. 24475-24483
-
-
Foury, F.1
Roganti, T.2
-
50
-
-
0037397764
-
Formation of iron-sulfur clusters in bacteria: An emerging field in bioinorganic chemistry
-
Frazzon J and Dean DR. Formation of iron-sulfur clusters in bacteria: an emerging field in bioinorganic chemistry. Curr Opin Chem Biol 7: 166-173, 2003.
-
(2003)
Curr Opin Chem Biol
, vol.7
, pp. 166-173
-
-
Frazzon, J.1
Dean, D.R.2
-
51
-
-
27144467097
-
Altered body iron distribution and rmicrocytosis in mice deficient in iron regulatory protein 2 (IRP2)
-
Galy B, Ferring D, Minana B, Bell O, Janser HG, Muckenthaler M, Schumann K, and Hentze MW. Altered body iron distribution and rmicrocytosis in mice deficient in iron regulatory protein 2 (IRP2). Blood 106: 2580-2589, 2005.
-
(2005)
Blood
, vol.106
, pp. 2580-2589
-
-
Galy, B.1
Ferring, D.2
Minana, B.3
Bell, O.4
Janser, H.G.5
Muckenthaler, M.6
Schumann, K.7
Hentze, M.W.8
-
52
-
-
33846650973
-
Molecular control of iron transport
-
Ganz T. Molecular control of iron transport. J Am Soc Nephrol 18: 394-400, 2007.
-
(2007)
J Am Soc Nephrol
, vol.18
, pp. 394-400
-
-
Ganz, T.1
-
53
-
-
0036839455
-
Biogenesis of iron-sulfur proteins in eukaryotes: Components, mechanism and pathology
-
Gerber J and Lill R. Biogenesis of iron-sulfur proteins in eukaryotes: components, mechanism and pathology. Mitochondrion 2: 71-86, 2002.
-
(2002)
Mitochondrion
, vol.2
, pp. 71-86
-
-
Gerber, J.1
Lill, R.2
-
54
-
-
5644288507
-
Targeting, import, and dimerization of a mammalian mitochondrial ATP binding cassette (ABC) transporter, ABCB10 (ABCme)
-
Graf SA, Haigh SE, Corson ED, and Shirihai OS. Targeting, import, and dimerization of a mammalian mitochondrial ATP binding cassette (ABC) transporter, ABCB10 (ABCme). J Biol Chem 279: 42954-42963, 2004.
-
(2004)
J Biol Chem
, vol.279
, pp. 42954-42963
-
-
Graf, S.A.1
Haigh, S.E.2
Corson, E.D.3
Shirihai, O.S.4
-
55
-
-
67349267792
-
Mutations in mitochondrial carrier family gene SLC25A38 cause nonsyndromic autosomal recessive congenital sideroblastic anemia
-
Guernsey DL, Jiang H, Campagna DR, Evans SC, Ferguson M, Kellogg MD, Lachance M, Matsuoka M, Nightingale M, Rideout A, Saint-Amant L, Schmidt PJ, Orr A, Bottomley SS, Fleming MD, Ludman M, Dyack S, Fernandez CV, and Samuels ME. Mutations in mitochondrial carrier family gene SLC25A38 cause nonsyndromic autosomal recessive congenital sideroblastic anemia. Nat Genet 41: 651-653, 2009.
-
(2009)
Nat Genet
, vol.41
, pp. 651-653
-
-
Guernsey, D.L.1
Jiang, H.2
Campagna, D.R.3
Evans, S.C.4
Ferguson, M.5
Kellogg, M.D.6
Lachance, M.7
Matsuoka, M.8
Nightingale, M.9
Rideout, A.10
Saint-Amant, L.11
Schmidt, P.J.12
Orr, A.13
Bottomley, S.S.14
Fleming, M.D.15
Ludman, M.16
Dyack, S.17
Fernandez, C.V.18
Samuels, M.E.19
-
56
-
-
18244389488
-
Iron-dependent regulation of the divalent metal ion transporter
-
Gunshin H, Allerson CR, Polycarpou-Schwarz M, Rofts A, Rogers JT, Kishi F, Hentze W, Rouault TA, Andrews NC, and Hediger MA. Iron-dependent regulation of the divalent metal ion transporter. FEBS Lett 509: 309-316, 2001.
-
(2001)
FEBS Lett
, vol.509
, pp. 309-316
-
-
Gunshin, H.1
Allerson, C.R.2
Polycarpou-Schwarz, M.3
Rofts, A.4
Rogers, J.T.5
Kishi, F.6
Hentze, W.7
Rouault, T.A.8
Andrews, N.C.9
Hediger, M.A.10
-
57
-
-
0029034338
-
Characterization and expression of iron regulatory protein-2 (IRP2)-presence of multiple IRP2, transcripts regulated by intracellular iron levels
-
Guo B, Brown FM, Phillips JD, Yu Y, and Leibold EA. Characterization and expression of iron regulatory protein-2 (IRP2)-presence of multiple IRP2, transcripts regulated by intracellular iron levels. J Biol Chem 270: 16529-16535, 1995.
-
(1995)
J Biol Chem
, vol.270
, pp. 16529-16535
-
-
Guo, B.1
Brown, F.M.2
Phillips, J.D.3
Yu, Y.4
Leibold, E.A.5
-
58
-
-
0027145130
-
Mitochondrial myopathy with succinatedehydrogenase and aconitase deficiency-abnormalities of several iron-sulfur proteins
-
Hall RE, Henriksson KG, Lewis SF, Haller RG, and Kennaway NG. Mitochondrial myopathy with succinatedehydrogenase and aconitase deficiency-abnormalities of several iron-sulfur proteins. J Clin Invest 92: 2660-2666, 1993.
-
(1993)
J Clin Invest
, vol.92
, pp. 2660-2666
-
-
Hall, R.E.1
Henriksson, K.G.2
Lewis, S.F.3
Haller, R.G.4
Kennaway, N.G.5
-
59
-
-
0025951154
-
Deficiency of skeletal-muscle succinate-dehydrogenase and aconitase-pathophysiology of exercise in a novel human muscle oxidative defect
-
Haller RG, Henriksson KG, Jorfeldt L, Hultman E, Wibom R, Sahlin K, Areskog NH, Gunder M, Ayyad K, Blomqvist CG, Hall RE, Thuillier P, Kennaway NG, and Lewis SF. Deficiency of skeletal-muscle succinate-dehydrogenase and aconitase-pathophysiology of exercise in a novel human muscle oxidative defect. J Clin Invest 88: 1197-1206, 1991.
-
(1991)
J Clin Invest
, vol.88
, pp. 1197-1206
-
-
Haller, R.G.1
Henriksson, K.G.2
Jorfeldt, L.3
Hultman, E.4
Wibom, R.5
Sahlin, K.6
Areskog, N.H.7
Gunder, M.8
Ayyad, K.9
Blomqvist, C.G.10
Hall, R.E.11
Thuillier, P.12
Kennaway, N.G.13
Lewis, S.F.14
-
60
-
-
0023612118
-
Identification of the iron-responsive element for the translational regulation of human ferritin messenger-RNA
-
Hentze MW, Caughman SW, Rouault TA, Barriocanal JG, Dancis A, Harford JB, and Klausner RD. Identification of the iron-responsive element for the translational regulation of human ferritin messenger-RNA. Science 238: 1570-1573, 1987.
-
(1987)
Science
, vol.238
, pp. 1570-1573
-
-
Hentze, M.W.1
Caughman, S.W.2
Rouault, T.A.3
Barriocanal, J.G.4
Dancis, A.5
Harford, J.B.6
Klausner, R.D.7
-
61
-
-
0029758487
-
Molecular control of vertebrate iron metabolism: MRNA-based regulatory circuits operated by iron, nitric oxide, and oxidative stress
-
Hentze MW and Kuhn LC. Molecular control of vertebrate iron metabolism: mRNA-based regulatory circuits operated by iron, nitric oxide, and oxidative stress. Proc Natl Acad Sci U S A 93: 8175-8182, 1996.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 8175-8182
-
-
Hentze, M.W.1
Kuhn, L.C.2
-
62
-
-
0023430885
-
A cis-acting element is necessary and sufficient for translational regulation of human ferritin expression in response to iron
-
Hentze MW, Rouault TA, Caughman SW, Dancis A, Harford JB, and Klausner RD. A cis-acting element is necessary and sufficient for translational regulation of human ferritin expression in response to iron. Proc Natl Acad Sci U S A 84: 6730-6734, 1987.
-
(1987)
Proc Natl Acad Sci U S A
, vol.84
, pp. 6730-6734
-
-
Hentze, M.W.1
Rouault, T.A.2
Caughman, S.W.3
Dancis, A.4
Harford, J.B.5
Klausner, R.D.6
-
63
-
-
77956218282
-
Mitochondrial iron metabolism and its role in neurodegeneration
-
Horowitz MP and Greenamyre JT. Mitochondrial iron metabolism and its role in neurodegeneration. J Alzheimers Dis 20 Suppl 2: S551-S68, 2010.
-
(2010)
J Alzheimers Dis 20 Suppl
, vol.2
-
-
Horowitz, M.P.1
Greenamyre, J.T.2
-
64
-
-
23644460325
-
A mouse model of juvenile hemochromatosis
-
Huang FW, Pinkus JL, Pinkus GS, Fleming MD, and Andrews NC. A mouse model of juvenile hemochromatosis. J Clin Invest 115: 2187-2191, 2005.
-
(2005)
J Clin Invest
, vol.115
, pp. 2187-2191
-
-
Huang, F.W.1
Pinkus, J.L.2
Pinkus, G.S.3
Fleming, M.D.4
Andrews, N.C.5
-
65
-
-
15744368845
-
Peroxisome proliferator-activated receptor gamma-independent ablation of cyclin D1 by thiazolidinediones and their derivatives in breast cancer cells
-
Huang JW, Shiau CW, Yang YT, Kulp SK, Chen KF, Brueggemeier RW, Shapiro CL, and Chen CS. Peroxisome proliferator-activated receptor gamma-independent ablation of cyclin D1 by thiazolidinediones and their derivatives in breast cancer cells. Mol Pharmacol 67: 1342-1348, 2005.
-
(2005)
Mol Pharmacol
, vol.67
, pp. 1342-1348
-
-
Huang, J.W.1
Shiau, C.W.2
Yang, Y.T.3
Kulp, S.K.4
Chen, K.F.5
Brueggemeier, R.W.6
Shapiro, C.L.7
Chen, C.S.8
-
66
-
-
70349504414
-
Elucidation of the mechanism of mitochondrial iron loading in Friedreich's ataxia by analysis of a mouse mutant
-
Huang ML-H, Becker EM, Whitnall M, Rahmanto YS, Ponka P, and Richardson DR. Elucidation of the mechanism of mitochondrial iron loading in Friedreich's ataxia by analysis of a mouse mutant. Proc Natl Acad Sci U S A 106: 16381-16386, 2009.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 16381-16386
-
-
Ml-H, H.1
Becker, E.M.2
Whitnall, M.3
Rahmanto, Y.S.4
Ponka, P.5
Richardson, D.R.6
-
67
-
-
0017700831
-
Low-molecular weight intracellular iron transport compounds
-
Jacobs A. Low-molecular weight intracellular iron transport compounds. Blood 50: 433-439, 1977.
-
(1977)
Blood
, vol.50
, pp. 433-439
-
-
Jacobs, A.1
-
68
-
-
0037108199
-
The labile iron pool: Characterization, measurement, and participation in cellular processes
-
Kakhlon O and Cabantchik ZI. The labile iron pool: characterization, measurement, and participation in cellular processes. Free Radic Biol Med 33: 1037-1046, 2002.
-
(2002)
Free Radic Biol Med
, vol.33
, pp. 1037-1046
-
-
Kakhlon, O.1
Cabantchik, Z.I.2
-
69
-
-
0030608677
-
The ABC transporter Atm1p is required for mitochondrial iron homeostasis
-
Kispal G, Csere P, Guiard B, and Lill R. The ABC transporter Atm1p is required for mitochondrial iron homeostasis. FEBS Lett 418: 346-350, 1997.
-
(1997)
FEBS Lett
, vol.418
, pp. 346-350
-
-
Kispal, G.1
Csere, P.2
Guiard, B.3
Lill, R.4
-
70
-
-
13444252281
-
Iron release from macrophages after erythrophagocytosis is up-regulated by ferroportin 1 overexpression and down-regulated by hepcidin
-
Knutson MD, Oukka M, Koss LM, Aydemir F, and Wessling-Resnick M. Iron release from macrophages after erythrophagocytosis is up-regulated by ferroportin 1 overexpression and down-regulated by hepcidin. Proc Natl Acad Sci U S A 102: 1324-1328, 2005.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 1324-1328
-
-
Knutson, M.D.1
Oukka, M.2
Koss, L.M.3
Aydemir, F.4
Wessling-Resnick, M.5
-
71
-
-
0345688910
-
Iron loading and erythrophagocytosis increase ferroportin 1 (FPN1) expression in J774 macrophages
-
Knutson MD, Vafa MR, Haile DJ, and Wessling-Resnick M. Iron loading and erythrophagocytosis increase ferroportin 1 (FPN1) expression in J774 macrophages. Blood 102: 4191-4197, 2003.
-
(2003)
Blood
, vol.102
, pp. 4191-4197
-
-
Knutson, M.D.1
Vafa, M.R.2
Haile, D.J.3
Wessling-Resnick, M.4
-
72
-
-
2442563409
-
Crystal structure of protoporphyrinogen IX oxidase: A key enzyme in haem and chlorophyll biosynthesis
-
Koch M, Breithaupt C, Kiefersauer R, Freigang J, Huber R, and Messerschmidt A. Crystal structure of protoporphyrinogen IX oxidase: a key enzyme in haem and chlorophyll biosynthesis. EMBO J 23: 1720-1728, 2004.
-
(2004)
EMBO J
, vol.23
, pp. 1720-1728
-
-
Koch, M.1
Breithaupt, C.2
Kiefersauer, R.3
Freigang, J.4
Huber, R.5
Messerschmidt, A.6
-
73
-
-
67749084367
-
Clinical manifestation and a new ISCU mutation in ironsulphur cluster deficiency myopathy
-
Kollberg G, Tulinius M, Melberg A, Darin N, Andersen O, Holmgren D, Oldfors A, and Holme E. Clinical manifestation and a new ISCU mutation in ironsulphur cluster deficiency myopathy. Brain 132: 2170-2179, 2009.
-
(2009)
Brain
, vol.132
, pp. 2170-2179
-
-
Kollberg, G.1
Tulinius, M.2
Melberg, A.3
Darin, N.4
Andersen, O.5
Holmgren, D.6
Oldfors, A.7
Holme, E.8
-
74
-
-
33749530252
-
Identification of a mammalian mitochondrial porphyrin transporter
-
Krishnamurthy PC, Du GQ, Fukuda Y, Sun DX, Sampath J, Mercer KE, Wang JF, Sosa-Pineda B, Murti KG, and Schuetz JD. Identification of a mammalian mitochondrial porphyrin transporter. Nature 443: 586-589, 2006.
-
(2006)
Nature
, vol.443
, pp. 586-589
-
-
Krishnamurthy, P.C.1
Du, G.Q.2
Fukuda, Y.3
Sun, D.X.4
Sampath, J.5
Mercer, K.E.6
Wang, J.F.7
Sosa-Pineda, B.8
Murti, K.G.9
Schuetz, J.D.10
-
75
-
-
0032245425
-
Targeting of a human iron-sulfur cluster assembly enzyme, nifs, to different subcellular compartments is regulated through alternative AUG utilization
-
Land T and Rouault TA. Targeting of a human iron-sulfur cluster assembly enzyme, nifs, to different subcellular compartments is regulated through alternative AUG utilization. Mol Cell 2: 807-815, 1998.
-
(1998)
Mol Cell
, vol.2
, pp. 807-815
-
-
Land, T.1
Rouault, T.A.2
-
76
-
-
0033516467
-
Mechanism of iron transport to the site of heme synthesis inside yeast mitochondria
-
Lange H, Kispal G, and Lill R. Mechanism of iron transport to the site of heme synthesis inside yeast mitochondria. J Biol Chem 274: 18989-18996, 1999.
-
(1999)
J Biol Chem
, vol.274
, pp. 18989-18996
-
-
Lange, H.1
Kispal, G.2
Lill, R.3
-
77
-
-
3142722152
-
The heme synthesis defect of mutants impaired in mitochondrial iron-sulfur protein biogenesis is caused by reversible inhibition of ferrochelatase
-
Lange H, Muhlenhoff U, Denzel M, Kispal G, and Lill R. The heme synthesis defect of mutants impaired in mitochondrial iron-sulfur protein biogenesis is caused by reversible inhibition of ferrochelatase. J Biol Chem 279: 29101-29108, 2004.
-
(2004)
J Biol Chem
, vol.279
, pp. 29101-29108
-
-
Lange, H.1
Muhlenhoff, U.2
Denzel, M.3
Kispal, G.4
Lill, R.5
-
78
-
-
0001731713
-
Hereditary metabolic myopathy with paroxysmal myoglobinuria due to abnormal glycolysis
-
Larsson LE, Sornas R, Linderholm H, Ringqvis T, and Muller R. Hereditary metabolic myopathy with paroxysmal myoglobinuria due to abnormal glycolysis. J Neurol Neurosurg Psychiatry 27: 361-380, 1964.
-
(1964)
J Neurol Neurosurg Psychiatry
, vol.27
, pp. 361-380
-
-
Larsson, L.E.1
Sornas, R.2
Linderholm, H.3
Ringqvis, T.4
Muller, R.5
-
79
-
-
0035138456
-
Targeted deletion of the gene encoding iron regulatory protein-2 causes misregulation of iron metabolism and neurodegenerative disease in mice
-
LaVaute T, Smith S, Cooperman S, Iwai K, Land W, Meyron-Holtz E, Drake SK, Miller G, Abu-AsabM, Tsokos M, Switzer R, Grinberg A, Love P, Tresser N, and Rouault TA. Targeted deletion of the gene encoding iron regulatory protein-2 causes misregulation of iron metabolism and neurodegenerative disease in mice. Nat Genet 27: 209-214, 2001.
-
(2001)
Nat Genet
, vol.27
, pp. 209-214
-
-
Lavaute, T.1
Smith, S.2
Cooperman, S.3
Iwai, K.4
Land, W.5
Meyron-Holtz, E.6
Drake, S.K.7
Miller, G.8
Abu-Asabm Tsokos, M.9
Switzer, R.10
Grinberg, A.11
Love, P.12
Tresser, N.13
Rouault, T.A.14
-
80
-
-
13844307889
-
-
Lee P, Peng H, Gelbart T, Wang L, and Beutler E. Regulation of hepcidin transcription by interleukin-1 and interleukin-6. Proc Natl Acad Sci U S A 102: 1906-1910, 2005.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 1906-1910
-
-
Lee, P.1
Peng, H.2
Gelbart, T.3
Wang, L.4
Beutler, E.5
-
81
-
-
0037447390
-
Iron use for haeme synthesis is under control of the yeast frataxin homologue (Yfh1)
-
Lesuisse E, Santos R, Matzanke BF, Knight SAB, Camadro JM, and Dancis A. Iron use for haeme synthesis is under control of the yeast frataxin homologue (Yfh1). Hum Mol Genet 12: 879-889, 2003.
-
(2003)
Hum Mol Genet
, vol.12
, pp. 879-889
-
-
Lesuisse, E.1
Santos, R.2
Matzanke, B.F.3
Sab, K.4
Camadro, J.M.5
Dancis, A.6
-
82
-
-
25444435160
-
Increased duodenal iron uptake and transfer in a rat model of chronic hypoxia is accompanied by reduced hepcidin expression
-
Leung PS, Srai SK, Mascarenhas M, Churchill LJ, and Debnam ES. Increased duodenal iron uptake and transfer in a rat model of chronic hypoxia is accompanied by reduced hepcidin expression. Gut 54: 1391-1395, 2005.
-
(2005)
Gut
, vol.54
, pp. 1391-1395
-
-
Leung, P.S.1
Srai, S.K.2
Mascarenhas, M.3
Churchill, L.J.4
Debnam, E.S.5
-
83
-
-
0035816608
-
A human mitochondrial ferritin encoded by an intronless gene
-
Levi S, Corsi B, Bosisio M, Invernizzi R, Volz A, Sanford D, Arosio P, and Drysdale J. A human mitochondrial ferritin encoded by an intronless gene. J Biol Chem 276: 24437-24440, 2001.
-
(2001)
J Biol Chem
, vol.276
, pp. 24437-24440
-
-
Levi, S.1
Corsi, B.2
Bosisio, M.3
Invernizzi, R.4
Volz, A.5
Sanford, D.6
Arosio, P.7
Drysdale, J.8
-
84
-
-
67349165712
-
The role of iron in mitochondrial function
-
Levi S and Rovida E. The role of iron in mitochondrial function. Biochim Biophys Acta 1790: 629-636, 2009.
-
(2009)
Biochim Biophys Acta
, vol.1790
, pp. 629-636
-
-
Levi, S.1
Rovida, E.2
-
85
-
-
68949128587
-
Function and biogenesis of iron-sulphur proteins
-
Lill R. Function and biogenesis of iron-sulphur proteins. Nature 460: 831-838, 2009.
-
(2009)
Nature
, vol.460
, pp. 831-838
-
-
Lill, R.1
-
86
-
-
33751177803
-
Iron-sulfur protein biogenesis in eukaryotes: Components and mechanisms
-
Lill R and Muhlenhoff U. Iron-sulfur protein biogenesis in eukaryotes: components and mechanisms. Annu Rev Cell Dev Biol 22: 457-486, 2006.
-
(2006)
Annu Rev Cell Dev Biol
, vol.22
, pp. 457-486
-
-
Lill, R.1
Muhlenhoff, U.2
-
87
-
-
27644526967
-
A mutation in Sec15l1 causes anemia in hemoglobin deficit (hbd) mice
-
Lim JE, Jin O, Bennett C, Morgan K, Wang FD, Trenor CC, Fleming MD, and Andrews NC. A mutation in Sec15l1 causes anemia in hemoglobin deficit (hbd) mice. Nat Genet 37: 1270-1273, 2005.
-
(2005)
Nat Genet
, vol.37
, pp. 1270-1273
-
-
Lim, J.E.1
Jin, O.2
Bennett, C.3
Morgan, K.4
Wang, F.D.5
Trenor, C.C.6
Fleming, M.D.7
Andrews, N.C.8
-
88
-
-
0025375790
-
Low succinate-dehydrogenase (SDH) activity in a patient with a hereditary myopathy with paroxysmal myoglobinuria
-
Linderholm H, Essengustavsson B, and Thornell LE. Low succinate-dehydrogenase (SDH) activity in a patient with a hereditary myopathy with paroxysmal myoglobinuria. J Intern Med 228: 43-52, 1990.
-
(1990)
J Intern Med
, vol.228
, pp. 43-52
-
-
Linderholm, H.1
Essengustavsson, B.2
Thornell, L.E.3
-
89
-
-
0033861745
-
A novel duodenal iron-regulated transporter, IREG1, implicated in the basolateral transfer of iron to the circulation
-
McKie AT, Marciani P, Rolfs A, Brennan K, Wehr K, Barrow D, Miret S, Bomford A, Peters TJ, Farzaneh F, Hediger MA, Hentze MW, and Simpson RJ. A novel duodenal iron-regulated transporter, IREG1, implicated in the basolateral transfer of iron to the circulation. Mol Cell 5: 299-309, 2000.
-
(2000)
Mol Cell
, vol.5
, pp. 299-309
-
-
McKie, A.T.1
Marciani, P.2
Rolfs, A.3
Brennan, K.4
Wehr, K.5
Barrow, D.6
Miret, S.7
Bomford, A.8
Peters, T.J.9
Farzaneh, F.10
Hediger, M.A.11
Hentze, M.W.12
Simpson, R.J.13
-
90
-
-
34848852657
-
A pi-helix switch selective for porphyrin deprotonation and product release in human ferrochelatase
-
Medlock AE, Dailey TA, Ross TA, Dailey HA, and Lanzilotta WN. A pi-helix switch selective for porphyrin deprotonation and product release in human ferrochelatase. J Mol Biol 373: 1006-1016, 2007.
-
(2007)
J Mol Biol
, vol.373
, pp. 1006-1016
-
-
Medlock, A.E.1
Dailey, T.A.2
Ross, T.A.3
Dailey, H.A.4
Lanzilotta, W.N.5
-
91
-
-
10744223491
-
Genetic ablations of iron regulatory proteins 1 and 2 reveal why iron regulatory protein 2 dominates iron homeostasis
-
Meyron-Holtz EG, Ghosh MC, Iwai K, LaVaute T, Brazzolotto X, Berger UV, Land W, Ollivierre-Wilson H, Grinberg A, Love P, and Rouault TA. Genetic ablations of iron regulatory proteins 1 and 2 reveal why iron regulatory protein 2 dominates iron homeostasis. EMBO J 23: 386-395, 2004.
-
(2004)
EMBO J
, vol.23
, pp. 386-395
-
-
Meyron-Holtz, E.G.1
Ghosh, M.C.2
Iwai, K.3
Lavaute, T.4
Brazzolotto, X.5
Berger, U.V.6
Land, W.7
Ollivierre-Wilson, H.8
Grinberg, A.9
Love, P.10
Rouault, T.A.11
-
92
-
-
0034625457
-
MTABC3, a novel mitochondrial ATPbinding cassette protein involved in iron homeostasis
-
Mitsuhashi N, Miki T, Senbongi H, Yokoi N, Yano H, Miyazaki M, Nakajima N, Iwanaga T, Yokoyama Y, Shibata T, and Seino S. MTABC3, a novel mitochondrial ATPbinding cassette protein involved in iron homeostasis. J Biol Chem 275: 17536-17540, 2000.
-
(2000)
J Biol Chem
, vol.275
, pp. 17536-17540
-
-
Mitsuhashi, N.1
Miki, T.2
Senbongi, H.3
Yokoi, N.4
Yano, H.5
Miyazaki, M.6
Nakajima, N.7
Iwanaga, T.8
Yokoyama, Y.9
Shibata, T.10
Seino, S.11
-
93
-
-
41149169596
-
Splice mutation in the iron-sulfur cluster scaffold protein ISCU causes myopathy with exercise intolerance
-
Mochel F, Knight MA, Tong WH, Hernandez D, Ayyad K, Taivassalo T, Andersen PM, Singleton A, Rouault TA, Fischbeck KH, and Haller RG. Splice mutation in the iron-sulfur cluster scaffold protein ISCU causes myopathy with exercise intolerance. Am J Hum Genet 82: 652-660, 2008.
-
(2008)
Am J Hum Genet
, vol.82
, pp. 652-660
-
-
Mochel, F.1
Knight, M.A.2
Tong, W.H.3
Hernandez, D.4
Ayyad, K.5
Taivassalo, T.6
Andersen, P.M.7
Singleton, A.8
Rouault, T.A.9
Fischbeck, K.H.10
Haller, R.G.11
-
94
-
-
0019860059
-
Transferrin biochemistry, physiology, and clinical significance
-
Morgan E. Transferrin biochemistry, physiology, and clinical significance. Mol Aspects Med 4: 1-123, 1981.
-
(1981)
Mol Aspects Med
, vol.4
, pp. 1-123
-
-
Morgan, E.1
-
95
-
-
0020524787
-
Chelator-mediated iron efflux from reticulocytes
-
Morgan EH. Chelator-mediated iron efflux from reticulocytes. Biochim Biophys Acta 733: 39-50, 1983.
-
(1983)
Biochim Biophys Acta
, vol.733
, pp. 39-50
-
-
Morgan, E.H.1
-
96
-
-
50949102412
-
Systemic iron homeostasis and the iron-responsive element/iron-regulatory protein (IRE/IRP) regulatory network
-
Muckenthaler MU, Galy B, and Hentze MW. Systemic iron homeostasis and the iron-responsive element/iron-regulatory protein (IRE/IRP) regulatory network. Annu Rev Nutr 28: 197-213, 2008.
-
(2008)
Annu Rev Nutr
, vol.28
, pp. 197-213
-
-
Muckenthaler, M.U.1
Galy, B.2
Hentze, M.W.3
-
97
-
-
17044451174
-
A specific role of the yeast mitochondrial carriers Mrs3/4p in mitochondrial iron acquisition under iron-limiting conditions
-
Muhlenhoff U, Stadler JA, Richhardt N, Seubert A, Eickhorst T, Schweyen RJ, Lill R, and Wiesenberger G. A specific role of the yeast mitochondrial carriers Mrs3/4p in mitochondrial iron acquisition under iron-limiting conditions. J Biol Chem 278: 40612-40620, 2003.
-
(2003)
J Biol Chem
, vol.278
, pp. 40612-40620
-
-
Muhlenhoff, U.1
Stadler, J.A.2
Richhardt, N.3
Seubert, A.4
Eickhorst, T.5
Schweyen, R.J.6
Lill, R.7
Wiesenberger, G.8
-
98
-
-
0034661480
-
Towards a structural understanding of Friedreich's ataxia: The solution structure of frataxin
-
Musco G, Stier G, Kolmerer B, Adinolfi S, Martin S, Frenkiel T, Gibson T, and Pastore A. Towards a structural understanding of Friedreich's ataxia: the solution structure of frataxin. Structure 8: 695-707, 2000.
-
(2000)
Structure
, vol.8
, pp. 695-707
-
-
Musco, G.1
Stier, G.2
Kolmerer, B.3
Adinolfi, S.4
Martin, S.5
Frenkiel, T.6
Gibson, T.7
Pastore, A.8
-
99
-
-
14944387002
-
Iron trafficking in the mitochondrion: Novel pathways revealed by disease
-
Napier I, Ponka P, and Richardson DR. Iron trafficking in the mitochondrion: novel pathways revealed by disease. Blood 105: 1867-1874, 2005.
-
(2005)
Blood
, vol.105
, pp. 1867-1874
-
-
Napier, I.1
Ponka, P.2
Richardson, D.R.3
-
100
-
-
2342510407
-
IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin
-
Nemeth E, Rivera S, Gabayan V, Keller C, Taudorf S, Pedersen BK, and Ganz T. IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin. J Clin Invest 113: 1271-1276, 2004.
-
(2004)
J Clin Invest
, vol.113
, pp. 1271-1276
-
-
Nemeth, E.1
Rivera, S.2
Gabayan, V.3
Keller, C.4
Taudorf, S.5
Pedersen, B.K.6
Ganz, T.7
-
101
-
-
13544250486
-
Hepcidin is decreased in TFR2 hemochromatosis
-
Nemeth E, Roetto A, Garozzo G, Ganz T, and Camaschella C. Hepcidin is decreased in TFR2 hemochromatosis. Blood 105: 1803-1806, 2005.
-
(2005)
Blood 105
, pp. 1803-1806
-
-
Nemeth, E.1
Roetto, A.2
Garozzo, G.3
Ganz, T.4
Camaschella, C.5
-
102
-
-
10844258104
-
Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization
-
Nemeth E, Tuttle MS, Powelson J, Vaughn MB, Donovan A, Ward DM, Ganz T, and Kaplan J. Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization. Science 306: 2090-2093, 2004.
-
(2004)
Science
, vol.306
, pp. 2090-2093
-
-
Nemeth, E.1
Tuttle, M.S.2
Powelson, J.3
Vaughn, M.B.4
Donovan, A.5
Ward, D.M.6
Ganz, T.7
Kaplan, J.8
-
103
-
-
0036791486
-
The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation
-
Nicolas G, Chauvet C, Viatte L, Danan JL, Bigard X, Devaux I, Beaumont C, Kahn A, and Vaulont S. The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation. J Clin Invest 110: 1037-1044, 2002.
-
(2002)
J Clin Invest
, vol.110
, pp. 1037-1044
-
-
Nicolas, G.1
Chauvet, C.2
Viatte, L.3
Danan, J.L.4
Bigard, X.5
Devaux, I.6
Beaumont, C.7
Kahn, A.8
Vaulont, S.9
-
104
-
-
14944358625
-
Overexpression of mitochondrial ferritin causes cytosolic iron depletion and changes cellular iron homeostasis
-
Nie GJ, Sheftel AD, Kim SF, and Ponka P. Overexpression of mitochondrial ferritin causes cytosolic iron depletion and changes cellular iron homeostasis. Blood 105: 2161-2167, 2005.
-
(2005)
Blood
, vol.105
, pp. 2161-2167
-
-
Nie, G.J.1
Sheftel, A.D.2
Kim, S.F.3
Ponka, P.4
-
105
-
-
27644455133
-
Identification of a ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells
-
Ohgami RS, Campagna DR, Greer EL, Antiochos B, McDonald A, Chen J, Sharp JJ, Fujiwara Y, Barker JE, and Fleming MD. Identification of a ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Nat Genet 37: 1264-1269, 2005.
-
(2005)
Nat Genet
, vol.37
, pp. 1264-1269
-
-
Ohgami, R.S.1
Campagna, D.R.2
Greer, E.L.3
Antiochos, B.4
McDonald, A.5
Chen, J.6
Sharp, J.J.7
Fujiwara, Y.8
Barker, J.E.9
Fleming, M.D.10
-
106
-
-
44349149346
-
Myopathy with lactic acidosis is linked to chromosome 12q23.3-24.11 and caused by an intron mutation in the ISCU gene resulting in a splicing defect
-
Olsson A, Lind L, Thornell LE, and Holmberg M. Myopathy with lactic acidosis is linked to chromosome 12q23.3-24.11 and caused by an intron mutation in the ISCU gene resulting in a splicing defect. Hum Mol Genet 17: 1666-1672, 2008.
-
(2008)
Hum Mol Genet
, vol.17
, pp. 1666-1672
-
-
Olsson, A.1
Lind, L.2
Thornell, L.E.3
Holmberg, M.4
-
107
-
-
9644284455
-
Supramolecular assemblies of human frataxin are formed via subunit-subunit interactions mediated by a non-conserved amino-terminal region
-
O'Neill HA, Gakh O, and Isaya G. Supramolecular assemblies of human frataxin are formed via subunit-subunit interactions mediated by a non-conserved amino-terminal region. J Mol Biol 345: 433-439, 2005.
-
(2005)
J Mol Biol
, vol.345
, pp. 433-439
-
-
O'Neill, H.A.1
Gakh, O.2
Isaya, G.3
-
108
-
-
12144274441
-
Assembly of human frataxin is a mechanism for detoxifying redox-active iron
-
O'Neill HA, Gakh O, Park S, Cui J, Mooney SM, Sampson M, Ferreira GC, and Isaya G. Assembly of human frataxin is a mechanism for detoxifying redox-active iron. Biochemistry 44: 537-545, 2005.
-
(2005)
Biochemistry
, vol.44
, pp. 537-545
-
-
O'Neill, H.A.1
Gakh, O.2
Park, S.3
Cui, J.4
Mooney, S.M.5
Sampson, M.6
Ferreira, G.C.7
Isaya, G.8
-
109
-
-
0021926630
-
Hereditary sideroblastic anaemia and ataxia: An X linked recessive disorder
-
Pagon RA, Bird TD, Detter JC, and Pierce I. Hereditary sideroblastic anaemia and ataxia: an X linked recessive disorder. J Med Genet 22: 267-273, 1985.
-
(1985)
J Med Genet
, vol.22
, pp. 267-273
-
-
Pagon, R.A.1
Bird, T.D.2
Detter, J.C.3
Pierce, I.4
-
110
-
-
33845245942
-
Suppression of hepcidin during anemia requires erythropoietic activity
-
Pak M, Lopez MA, Gabayan V, Ganz T, and Rivera S. Suppression of hepcidin during anemia requires erythropoietic activity. Blood 108: 3730-3735, 2006.
-
(2006)
Blood
, vol.108
, pp. 3730-3735
-
-
Pak, M.1
Lopez, M.A.2
Gabayan, V.3
Ganz, T.4
Rivera, S.5
-
111
-
-
0035896642
-
Hepcidin, a urinary antimicrobial peptide synthesized in the liver
-
Park CH, Valore EV, Waring AJ, and Ganz T. Hepcidin, a urinary antimicrobial peptide synthesized in the liver. J Biol Chem 276: 7806-7810, 2001.
-
(2001)
J Biol Chem
, vol.276
, pp. 7806-7810
-
-
Park, C.H.1
Valore, E.V.2
Waring, A.J.3
Ganz, T.4
-
112
-
-
0037064027
-
The ferroxidase activity of yeast frataxin
-
Park S, Gakh O, Mooney SM, and Isaya G. The ferroxidase activity of yeast frataxin. J Biol Chem 277: 38589-38595, 2002.
-
(2002)
J Biol Chem
, vol.277
, pp. 38589-38595
-
-
Park, S.1
Gakh, O.2
Mooney, S.M.3
Isaya, G.4
-
113
-
-
0042232045
-
Yeast frataxin sequentially chaperones and stores iron by coupling protein assembly with iron oxidation
-
Park S, Gakh O, O'Neill HA, Mangravita A, Nichol H, Ferreira GC, and Isaya G. Yeast frataxin sequentially chaperones and stores iron by coupling protein assembly with iron oxidation. J Biol Chem 278: 31340-31351, 2003.
-
(2003)
J Biol Chem
, vol.278
, pp. 31340-31351
-
-
Park, S.1
Gakh, O.2
O'Neill, H.A.3
Mangravita, A.4
Nichol, H.5
Ferreira, G.C.6
Isaya, G.7
-
114
-
-
67650351904
-
Hepcidin, the hormone of iron metabolism, is bound specifically to alpha-2-macroglobulin in blood
-
Peslova G, Petrak J, Kuzelova K, Hrdy I, Halada P, Kuchel PW, Soe-Lin S, Ponka P, Sutak R, Becker E, Huang MLH, Rahmanto YS, Richardson DR, and Vyoral D. Hepcidin, the hormone of iron metabolism, is bound specifically to alpha-2-macroglobulin in blood. Blood 113: 6225-6236, 2009.
-
(2009)
Blood
, vol.113
, pp. 6225-6236
-
-
Peslova, G.1
Petrak, J.2
Kuzelova, K.3
Hrdy, I.4
Halada, P.5
Kuchel, P.W.6
Soe-Lin, S.7
Ponka, P.8
Sutak, R.9
Becker, E.10
Mlh, H.11
Rahmanto, Y.S.12
Richardson, D.R.13
Vyoral, D.14
-
115
-
-
33644772614
-
The mitochondrial ATP-binding cassette transporter Abcb7 is essential in mice and participates in cytosolic iron-sulfur cluster biogenesis
-
Pondarre C, Antiochos BB, Campagna DR, Greer EL, Deck KM, McDonald A, Han AP, Medlock A, Kutok JL, Anderson SA, Eisenstein RS, and Fleming MD. The mitochondrial ATP-binding cassette transporter Abcb7 is essential in mice and participates in cytosolic iron-sulfur cluster biogenesis. Hum Mol Genet 15: 953-964, 2006.
-
(2006)
Hum Mol Genet
, vol.15
, pp. 953-964
-
-
Pondarre, C.1
Antiochos, B.B.2
Campagna, D.R.3
Greer, E.L.4
Deck, K.M.5
McDonald, A.6
Han, A.P.7
Medlock, A.8
Kutok, J.L.9
Anderson, S.A.10
Eisenstein, R.S.11
Fleming, M.D.12
-
116
-
-
0031028178
-
Tissue-specific regulation of iron metabolism and heme synthesis: Distinct control mechanism in erythroid cells
-
Ponka P. Tissue-specific regulation of iron metabolism and heme synthesis: distinct control mechanism in erythroid cells. Blood 89: 1-25, 1997.
-
(1997)
Blood
, vol.89
, pp. 1-25
-
-
Ponka, P.1
-
118
-
-
0027161470
-
In-situ conversion of coproporphyrinogen to heme by murine mitochondria-terminal steps of the heme biosyntheticpathway
-
Proulx KL, Woodard SI, and Dailey HA. In-situ conversion of coproporphyrinogen to heme by murine mitochondria-terminal steps of the heme biosyntheticpathway. Protein Sci 2: 1092-1098, 1993.
-
(1993)
Protein Sci
, vol.2
, pp. 1092-1098
-
-
Proulx, K.L.1
Woodard, S.I.2
Dailey, H.A.3
-
119
-
-
0035138072
-
Mouse models for Friedreich ataxia exhibit cardiomyopathy, sensory nerve defect and Fe-S enzyme deficiency followed by intramitochondrial iron deposits
-
Puccio H, Simon D, Cossee M, Criqui-Filipe P, Tiziano F, Melki J, Hindelang C, Matyas R, Rustin P, and Koenig M. Mouse models for Friedreich ataxia exhibit cardiomyopathy, sensory nerve defect and Fe-S enzyme deficiency followed by intramitochondrial iron deposits. Nat Genet 27: 181-186, 2001.
-
(2001)
Nat Genet
, vol.27
, pp. 181-186
-
-
Puccio, H.1
Simon, D.2
Cossee, M.3
Criqui-Filipe, P.4
Tiziano, F.5
Melki, J.6
Hindelang, C.7
Matyas, R.8
Rustin, P.9
Koenig, M.10
-
120
-
-
77954627973
-
Mitochondrial iron trafficking and the integration of iron metabolism between the mitochondrion and cytosol
-
Richardson DR, Lane DJR, Becker EM, Huang MLH, Whitnall M, Rahmanto YS, Sheftel AD, and Ponka P. Mitochondrial iron trafficking and the integration of iron metabolism between the mitochondrion and cytosol. Proc Natl Acad Sci U S A 107: 10775-10782, 2010.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 10775-10782
-
-
Richardson, D.R.1
Djr, L.2
Becker, E.M.3
Mlh, H.4
Whitnall, M.5
Rahmanto, Y.S.6
Sheftel, A.D.7
Ponka, P.8
-
121
-
-
0031567095
-
The molecular mechanisms of the metabolism and transport of iron in normal and neoplastic cells
-
Richardson DR and Ponka P. The molecular mechanisms of the metabolism and transport of iron in normal and neoplastic cells. Biochim Biophys Acta 1331: 1-40, 1997.
-
(1997)
Biochim Biophys Acta
, vol.1331
, pp. 1-40
-
-
Richardson, D.R.1
Ponka, P.2
-
122
-
-
0029865751
-
Distribution of iron in reticulocytes after inhibition of heme synthesis with succinylacetone: Examination of the intermediates involved in iron metabolism
-
Richardson DR, Ponka P, and Vyoral D. Distribution of iron in reticulocytes after inhibition of heme synthesis with succinylacetone: examination of the intermediates involved in iron metabolism. Blood 87: 3477-3488, 1996.
-
(1996)
Blood
, vol.87
, pp. 3477-3488
-
-
Richardson, D.R.1
Ponka, P.2
Vyoral, D.3
-
123
-
-
13544252463
-
Hepcidin excess induces the sequestration of iron and exacerbates tumor-associated anemia
-
Rivera S, Liu L, Nemeth E, Gabayan V, Sorensen OE, and Ganz T. Hepcidin excess induces the sequestration of iron and exacerbates tumor-associated anemia. Blood 105: 1797-1802, 2005.
-
(2005)
Blood
, vol.105
, pp. 1797-1802
-
-
Rivera, S.1
Liu, L.2
Nemeth, E.3
Gabayan, V.4
Sorensen, O.E.5
Ganz, T.6
-
124
-
-
0036226063
-
Grx5 is a mitochondrial glutaredoxin required for the activity of iron/sulfur enzymes
-
Rodriguez-Manzaneque MT, Tamarit J, Belli G, Ros J, and Herrero E. Grx5 is a mitochondrial glutaredoxin required for the activity of iron/sulfur enzymes. Mol Biol Cell 13: 1109-1121, 2002.
-
(2002)
Mol Biol Cell
, vol.13
, pp. 1109-1121
-
-
Rodriguez-Manzaneque, M.T.1
Tamarit, J.2
Belli, G.3
Ros, J.4
Herrero, E.5
-
125
-
-
0031253821
-
Aconitase and mitochondrial iron-sulphur protein deficiency in Friedreich ataxia
-
Rotig A, de Lonlay P, Chretien D, Foury F, Koenig M, Sidi D, Munnich A, and Rustin P. Aconitase and mitochondrial iron-sulphur protein deficiency in Friedreich ataxia. Nat Genet 17: 215-217, 1997.
-
(1997)
Nat Genet
, vol.17
, pp. 215-217
-
-
Rotig, A.1
De Lonlay, P.2
Chretien, D.3
Foury, F.4
Koenig, M.5
Sidi, D.6
Munnich, A.7
Rustin, P.8
-
126
-
-
47249142777
-
Iron-sulfur cluster biogenesis and human disease
-
Rouault TA and Tong WH. Iron-sulfur cluster biogenesis and human disease. Trends Genet 24: 398-407, 2008.
-
(2008)
Trends Genet
, vol.24
, pp. 398-407
-
-
Rouault, T.A.1
Tong, W.H.2
-
127
-
-
33645758306
-
A splice-supporting intronic mutation in the last bp position of a cryptic exon within intron 6 of the CYBB gene induces its incorporation into the mRNA causing chronic granulomatous disease (CGD)
-
Rump A, Rosen-Wolff A, Gahr M, Seidenberg J, Roos C, Walter L, Gunther V, and Roesler J. A splice-supporting intronic mutation in the last bp position of a cryptic exon within intron 6 of the CYBB gene induces its incorporation into the mRNA causing chronic granulomatous disease (CGD). Gene 371: 174-181, 2006.
-
(2006)
Gene
, vol.371
, pp. 174-181
-
-
Rump, A.1
Rosen-Wolff, A.2
Gahr, M.3
Seidenberg, J.4
Roos, C.5
Walter, L.6
Gunther, V.7
Roesler, J.8
-
128
-
-
0035920101
-
A self-associated complex formed at long GAA-TTC repeats in intron 1 of the frataxin gene, inhibits transcription
-
Sakamoto N, Ohshima K, Montermini L, Pandolfo M, and Wells RD. Sticky DNA, a self-associated complex formed at long GAA-TTC repeats in intron 1 of the frataxin gene, inhibits transcription. J Biol Chem 276: 27171-27177, 2001.
-
(2001)
J Biol Chem
, vol.276
, pp. 27171-27177
-
-
Sakamoto, N.1
Ohshima, K.2
Montermini, L.3
Pandolfo, M.4
Wells, R.D.5
Sticky, D.N.A.6
-
129
-
-
70350576223
-
An E3 ligase possessing an iron-responsive hemerythrin domain is a regulator of iron homeostasis
-
Salahudeen AA, Thompson JW, Ruiz JC, Ma HW, Kinch LN, Li QM, Grishin NV, and Bruick RK. An E3 ligase possessing an iron-responsive hemerythrin domain is a regulator of iron homeostasis. Science 326: 722-726, 2009.
-
(2009)
Science
, vol.326
, pp. 722-726
-
-
Salahudeen, A.A.1
Thompson, J.W.2
Ruiz, J.C.3
Ma, H.W.4
Kinch, L.N.5
Li, Q.M.6
Grishin, N.V.7
Bruick, R.K.8
-
130
-
-
35548967459
-
Mitochondrial ferritin expression in adult mouse tissues
-
Santambrogio P, Biasiotto G, Sanvito F, Olivieri S, Arosio P, and Levi S. Mitochondrial ferritin expression in adult mouse tissues. J Histochem Cytochem 55: 1129-1137, 2007.
-
(2007)
J Histochem Cytochem
, vol.55
, pp. 1129-1137
-
-
Santambrogio, P.1
Biasiotto, G.2
Sanvito, F.3
Olivieri, S.4
Arosio, P.5
Levi, S.6
-
131
-
-
60549083568
-
Mitochondrial dysfunction in neurodegenerative diseases
-
Schapira AHV. Mitochondrial dysfunction in neurodegenerative diseases. Neurochem Res 33: 2502-2509, 2008.
-
(2008)
Neurochem Res
, vol.33
, pp. 2502-2509
-
-
Schapira, A.H.V.1
-
132
-
-
29644442275
-
Frataxin deficiency alters heme pathway transcripts and decreases mitochondrial heme metabolites in mammalian cells
-
Schoenfeld RA, Napoli E, Wong A, Zhan S, Reutenauer L, Morin D, Buckpitt AR, Taroni F, Lonnerdal B, Ristow M, Puccio H, and Cortopassi GA. Frataxin deficiency alters heme pathway transcripts and decreases mitochondrial heme metabolites in mammalian cells. Hum Mol Genet 14: 3787-3799, 2005.
-
(2005)
Hum Mol Genet
, vol.14
, pp. 3787-3799
-
-
Schoenfeld, R.A.1
Napoli, E.2
Wong, A.3
Zhan, S.4
Reutenauer, L.5
Morin, D.6
Buckpitt, A.R.7
Taroni, F.8
Lonnerdal, B.9
Ristow, M.10
Puccio, H.11
Cortopassi, G.A.12
-
133
-
-
33644748145
-
Mitoferrin is essential for erythroid iron assimilation
-
Shaw GC, Cope JJ, Li L, Corson K, Hersey C, Ackermann GE, Gwynn B, Lambert AJ, Wingert RA, Traver D, Trede NS, Barut BA, Zhou Y, Minet E, Donovan A, Brownlie A, Balzan R, Weiss MJ, Peters LL, Kaplan J, Zon LI, and Paw BH. Mitoferrin is essential for erythroid iron assimilation. Nature 440: 96-100, 2006.
-
(2006)
Nature
, vol.440
, pp. 96-100
-
-
Shaw, G.C.1
Cope, J.J.2
Li, L.3
Corson, K.4
Hersey, C.5
Ackermann, G.E.6
Gwynn, B.7
Lambert, A.J.8
Wingert, R.A.9
Traver, D.10
Trede, N.S.11
Barut, B.A.12
Zhou, Y.13
Minet, E.14
Donovan, A.15
Brownlie, A.16
Balzan, R.17
Weiss, M.J.18
Peters, L.L.19
Kaplan, J.20
Zon, L.I.21
Paw, B.H.22
more..
-
135
-
-
34347375300
-
Direct interorganellar transfer of iron from endosome to mitochondrion
-
Sheftel AD, Zhang AS, Brown C, Shirihai OS, and Ponka P. Direct interorganellar transfer of iron from endosome to mitochondrion. Blood 110: 125-132, 2007.
-
(2007)
Blood
, vol.110
, pp. 125-132
-
-
Sheftel, A.D.1
Zhang, A.S.2
Brown, C.3
Shirihai, O.S.4
Ponka, P.5
-
136
-
-
0031616020
-
Cloning and chromosomal mapping of a novel ABC transporter gene (hABC7), a candidate for X-linked sideroblastic anemia with spinocerebellar ataxia
-
Shimada Y, Okuno S, Kawai A, Shinomiya H, Saito A, Suzuki M, Omori Y, Nishino N, Kanemoto N, Fujiwara T, Horie M, and Takahashi E. Cloning and chromosomal mapping of a novel ABC transporter gene (hABC7), a candidate for X-linked sideroblastic anemia with spinocerebellar ataxia. J Hum Genet 43: 115-122, 1998.
-
(1998)
J Hum Genet
, vol.43
, pp. 115-122
-
-
Shimada, Y.1
Okuno, S.2
Kawai, A.3
Shinomiya, H.4
Saito, A.5
Suzuki, M.6
Omori, Y.7
Nishino, N.8
Kanemoto, N.9
Fujiwara, T.10
Horie, M.11
Takahashi, E.12
-
137
-
-
0034213588
-
ABC-me: A novel mitochondrial transporter induced by GATA-1 during erythroid differentiation
-
Shirihai OS, Gregory T, Yu CN, Orkin SH, and Weiss MJ. ABC-me: a novel mitochondrial transporter induced by GATA-1 during erythroid differentiation. EMBO J 19: 2492-2502, 2000.
-
(2000)
EMBO J
, vol.19
, pp. 2492-2502
-
-
Shirihai, O.S.1
Gregory, T.2
Yu, C.N.3
Orkin, S.H.4
Weiss, M.J.5
-
138
-
-
35048833703
-
Non-transferrin-bound iron reaches mitochondria by a chelator- inaccessible mechanism: Biological and clinical implications
-
Shvartsman M, Kikkeri R, Shanzer A, and Cabantchik ZI. Non-transferrin-bound iron reaches mitochondria by a chelator-inaccessible mechanism: biological and clinical implications. Am J Physiol Cell Physiol 293: C1383-C1394, 2007.
-
(2007)
Am J Physiol Cell Physiol
, vol.293
-
-
Shvartsman, M.1
Kikkeri, R.2
Shanzer, A.3
Cabantchik, Z.I.4
-
139
-
-
11144353669
-
Severity of neurodegeneration correlates with compromise of iron metabolism in mice with iron regulatory protein deficiencies
-
Smith SR, Cooperman S, Lavaute T, Tresser N, Ghosh M, Meyron-Holtz E, Land W, Ollivierre H, Jortner B, Switzer R, Messing A, and Rouault TA. Severity of neurodegeneration correlates with compromise of iron metabolism in mice with iron regulatory protein deficiencies. Ann N Y Acad Sci 1012: 65-83, 2004.
-
(2004)
Ann N y Acad Sci
, vol.1012
, pp. 65-83
-
-
Smith, S.R.1
Cooperman, S.2
Lavaute, T.3
Tresser, N.4
Ghosh, M.5
Meyron-Holtz, E.6
Land, W.7
Ollivierre, H.8
Jortner, B.9
Switzer, R.10
Messing, A.11
Rouault, T.A.12
-
140
-
-
0037944100
-
Involvement of ABC7 in the biosynthesis of heme in erythroid cells: Interaction of ABC7 with ferrochelatase
-
Taketani S, Kakimoto K, Ueta H, Masaki R, and Furukawa T. Involvement of ABC7 in the biosynthesis of heme in erythroid cells: interaction of ABC7 with ferrochelatase. Blood 101: 3274-3280, 2003.
-
(2003)
Blood
, vol.101
, pp. 3274-3280
-
-
Taketani, S.1
Kakimoto, K.2
Ueta, H.3
Masaki, R.4
Furukawa, T.5
-
141
-
-
0041691163
-
Subcellular compartmentalization of human Nfu, an ironsulfur cluster scaffold protein, and its ability to assemble a 4Fe-4S cluster
-
Tong WH, Jameson GNL, Huynh BH, and Rouault TA. Subcellular compartmentalization of human Nfu, an ironsulfur cluster scaffold protein, and its ability to assemble a 4Fe-4S cluster. Proc Natl Acad Sci U S A 100: 9762-9767, 2003.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 9762-9767
-
-
Tong, W.H.1
Gnl, J.2
Huynh, B.H.3
Rouault, T.A.4
-
142
-
-
0034331239
-
Distinct iron-sulfur cluster assembly complexes exist in the cytosol and mitochondria of human cells
-
Tong WH and Rouault T. Distinct iron-sulfur cluster assembly complexes exist in the cytosol and mitochondria of human cells. EMBO J 19: 5692-5700, 2000.
-
(2000)
EMBO J
, vol.19
, pp. 5692-5700
-
-
Tong, W.H.1
Rouault, T.2
-
143
-
-
33644623262
-
Functions of mitochondrial ISCU and cytosolic ISCU in mammalian iron-sulfur cluster biogenesis and iron homeostasis
-
Tong WH and Rouault TA. Functions of mitochondrial ISCU and cytosolic ISCU in mammalian iron-sulfur cluster biogenesis and iron homeostasis. Cell Metab 3: 199-210, 2006.
-
(2006)
Cell Metab
, vol.3
, pp. 199-210
-
-
Tong, W.H.1
Rouault, T.A.2
-
144
-
-
70350613915
-
Control of iron homeostasis by an iron-regulated ubiquitin ligase
-
Vashisht AA, Zumbrennen KB, Huang XH, Powers DN, Durazo A, Sun DH, Bhaskaran N, Persson A, Uhlen M, Sangfelt O, Spruck C, Leibold EA, and Wohlschlegel JA. Control of iron homeostasis by an iron-regulated ubiquitin ligase. Science 326: 718-721, 2009.
-
(2009)
Science
, vol.326
, pp. 718-721
-
-
Vashisht, A.A.1
Zumbrennen, K.B.2
Huang, X.H.3
Powers, D.N.4
Durazo, A.5
Sun, D.H.6
Bhaskaran, N.7
Persson, A.8
Uhlen, M.9
Sangfelt, O.10
Spruck, C.11
Leibold, E.A.12
Wohlschlegel, J.A.13
-
145
-
-
33745742487
-
Hepcidin mRNA levels in mouse liver respond to inhibition of erythropoiesis
-
Vokurka M, Krijt J, Sulc K, and Necas E. Hepcidin mRNA levels in mouse liver respond to inhibition of erythropoiesis. Physiol Res 55: 667-674, 2006.
-
(2006)
Physiol Res
, vol.55
, pp. 667-674
-
-
Vokurka, M.1
Krijt, J.2
Sulc, K.3
Necas, E.4
-
146
-
-
0026775830
-
Transferrin and iron distribution in subcellular-fractions of K562 cells in the early stages of transferrin endocytosis
-
Vyoral D, Hradilek A, and Neuwirt J. Transferrin and iron distribution in subcellular-fractions of K562 cells in the early stages of transferrin endocytosis. Biochim Biophys Acta 1137: 148-154, 1992.
-
(1992)
Biochim Biophys Acta
, vol.1137
, pp. 148-154
-
-
Vyoral, D.1
Hradilek, A.2
Neuwirt, J.3
-
147
-
-
45549107531
-
Binding of yeast frataxin to the scaffold for Fe-S cluster biogenesis, Isu
-
Wang T and Craig EA. Binding of yeast frataxin to the scaffold for Fe-S cluster biogenesis, Isu. J Biol Chem 283: 12674-12679, 2008.
-
(2008)
J Biol Chem
, vol.283
, pp. 12674-12679
-
-
Wang, T.1
Craig, E.A.2
-
148
-
-
34548307253
-
Excess capacity of the iron regulatory protein system
-
Wang W, Di X, D'Agostino RB, Torti SV, and Torti FM. Excess capacity of the iron regulatory protein system. J Biol Chem 282: 24650-24659, 2007.
-
(2007)
J Biol Chem
, vol.282
, pp. 24650-24659
-
-
Wang, W.1
Di D'Agostino, X.R.B.2
Torti, S.V.3
Torti, F.M.4
-
149
-
-
47749130452
-
The MCK mouse heart model of Friedreich's ataxia: Alterations in iron-regulated proteins and cardiac hypertrophy are limited by iron chelation
-
Whitnall M, Rahmanto YS, Sutak R, Xu X, Becker EM, Mikhael MR, Ponka P, and Richardson DR. The MCK mouse heart model of Friedreich's ataxia: alterations in iron-regulated proteins and cardiac hypertrophy are limited by iron chelation. Proc Natl Acad Sci U S A 105: 9757-9762, 2008.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 9757-9762
-
-
Whitnall, M.1
Rahmanto, Y.S.2
Sutak, R.3
Xu, X.4
Becker, E.M.5
Mikhael, M.R.6
Ponka, P.7
Richardson, D.R.8
-
150
-
-
23944500052
-
Deficiency of glutaredoxin 5 reveals Fe-S clusters are required for vertebrate haem synthesis
-
Wingert RA, Galloway JL, Barut B, Foott H, Fraenkel P, Axe JL, Weber GJ, Dooley K, Davidson AJ, Schmidt B, Paw BH, Shaw GC, Kingsley P, Palis J, Schubert H, Chen O, Kaplan J, and Zon LI. Deficiency of glutaredoxin 5 reveals Fe-S clusters are required for vertebrate haem synthesis. Nature 436: 1035-1039, 2005.
-
(2005)
Nature
, vol.436
, pp. 1035-1039
-
-
Wingert, R.A.1
Galloway, J.L.2
Barut, B.3
Foott, H.4
Fraenkel, P.5
Axe, J.L.6
Weber, G.J.7
Dooley, K.8
Davidson, A.J.9
Schmidt, B.10
Paw, B.H.11
Shaw, G.C.12
Kingsley, P.13
Palis, J.14
Schubert, H.15
Chen, O.16
Kaplan, J.17
Zon, L.I.18
-
151
-
-
77951843593
-
Glutaredoxin 5 deficiency causes sideroblastic anemia by specifically impairing heme biosynthesis and depleting cytosolic iron in human erythroblasts
-
Ye H, Jeong SY, Ghosh MC, Kovtunovych G, Silvestri L, Ortillo D, Uchida N, Tisdale J, Camaschella C, and Rouault TA. Glutaredoxin 5 deficiency causes sideroblastic anemia by specifically impairing heme biosynthesis and depleting cytosolic iron in human erythroblasts. J Clin Invest 120: 1749-1761, 2010.
-
(2010)
J Clin Invest
, vol.120
, pp. 1749-1761
-
-
Ye, H.1
Jeong, S.Y.2
Ghosh, M.C.3
Kovtunovych, G.4
Silvestri, L.5
Ortillo, D.6
Uchida, N.7
Tisdale, J.8
Camaschella, C.9
Rouault, T.A.10
-
152
-
-
2942744572
-
Frataxin-mediated iron delivery to ferrochelatase in the final step of heme biosynthesis
-
Yoon T and Cowan JA. Frataxin-mediated iron delivery to ferrochelatase in the final step of heme biosynthesis. J Biol Chem 279: 25943-25946, 2004.
-
(2004)
J Biol Chem
, vol.279
, pp. 25943-25946
-
-
Yoon, T.1
Cowan, J.A.2
-
153
-
-
0037613459
-
Iron-sulfur cluster biosynthesis. Characterization of frataxin as an iron donor for assembly of [2Fe-2S] clusters in ISU-type proteins
-
Yoon T and Cowan JA. Iron-sulfur cluster biosynthesis. Characterization of frataxin as an iron donor for assembly of [2Fe-2S] clusters in ISU-type proteins. J Am Chem Soc 125: 6078-6084, 2003.
-
(2003)
J Am Chem Soc
, vol.125
, pp. 6078-6084
-
-
Yoon, T.1
Cowan, J.A.2
-
154
-
-
33646104690
-
The anemia of "haemoglobin-deficit" (hbd/hbd) mice is caused by a defect in transferrin cycling
-
Zhang AS, Sheftel AD, and Ponka P. The anemia of "haemoglobin- deficit" (hbd/hbd) mice is caused by a defect in transferrin cycling. Exp Hematol 34: 593-598, 2006.
-
(2006)
Exp Hematol
, vol.34
, pp. 593-598
-
-
Zhang, A.S.1
Sheftel, A.D.2
Ponka, P.3
-
155
-
-
11144226961
-
Intracellular kinetics of iron in reticulocytes: Evidence for endosome involvement in iron targeting to mitochondria
-
Zhang AS, Sheftel AD, and Ponka P. Intracellular kinetics of iron in reticulocytes: evidence for endosome involvement in iron targeting to mitochondria. Blood 105: 368-375, 2005.
-
(2005)
Blood
, vol.105
, pp. 368-375
-
-
Zhang, A.S.1
Sheftel, A.D.2
Ponka, P.3
-
156
-
-
0027048349
-
Binding of cytosolic aconitase to the iron responsive element of porcine mitochondrial aconitase messenger-RNA
-
Zheng LM, Kennedy MC, Blondin GA, Beinert H, and Zalkin H. Binding of cytosolic aconitase to the iron responsive element of porcine mitochondrial aconitase messenger-RNA. Arch Biochem Biophys 299: 356-360, 1992.
-
(1992)
Arch Biochem Biophys
, vol.299
, pp. 356-360
-
-
Zheng, L.M.1
Kennedy, M.C.2
Blondin, G.A.3
Beinert, H.4
Zalkin, H.5
|