Excess capacity of the iron regulatory protein system

Journal of Biological Chemistry

Volumn 282, Issue 34, 2007, Pages 24650-24659

  Wang, Wei ^a   Di, Xiumin ^a   D'Agostino Jr , Ralph B ^a   Torti, Suzy V ^a   Torti, Frank M ^a  

^a WAKE FOREST UNIVERSITY HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLULAR IRON METABOLISM; IRON REGULATORY PROTEIN SYSTEM; IRON STORAGE;

CELLS; CHEMICAL BONDS; GENE EXPRESSION; IRON; MAMMALS; RNA;

PROTEINS;

CD71 ANTIGEN; FERRITIN; FERRITIN H; IRON REGULATORY PROTEIN 1; IRON REGULATORY PROTEIN 2; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; IRON METABOLISM; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; FERRITINS; GENE SILENCING; HELA CELLS; HUMANS; IRON; IRON REGULATORY PROTEIN 1; IRON REGULATORY PROTEIN 2; LUCIFERASES; MICE; MODELS, BIOLOGICAL; RECEPTORS, TRANSFERRIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; RNA, SMALL INTERFERING;

MAMMALIA;

EID: 34548307253     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M703167200     Document Type: Article

References (53)

1. Hentze, M. W., Muckenthaler, M. U., and Andrews, N. C. (2004) Cell 117, 285-297
2. Hentze, M. W., Rouault, T. A., Caughman, S. W., Dancis, A., Harford, J. B., and Klausner, R. D. (1987) Proc. Natl. Acad. Sci. U. S. A. 84, 6730-6734
3. Aziz, N., and Munro, H. N. (1987) Proc. Natl. Acad. Sci. U. S. A. 84, 8478-8482
4. Hentze, M. W., Caughman, S. W., Rouault, T. A., Barriocanal, J. G., Dancis, A., Harford, J. B., and Klausner, R. D. (1987) Science 238, 1570-1573
5. Casey, J. L., Hentze, M. W., Koeller, D. M., Caughman, S. W., Rouault, T. A., Klausner, R. D., and Harford, J. B. (1988) Science 240, 924-928
6. Mullner, E. W., and Kuhn, L. C. (1988) Cell 53, 815-825
7. Gunshin, H., Mackenzie, B., Berger, U. V., Gunshin, Y., Romero, M. F., Boron, W. F., Nussberger, S., Gollan, J. L., and Hediger, M. A. (1997) Nature 388, 482-488
8. Gunshin, H., Allerson, C. R., Polycarpou-Schwarz, M., Rofts, A., Rogers, J. T., Kishi, F., Hentze, M. W., Rouault, T. A., Andrews, N. C., and Hediger, M. A. (2001) FEBS Lett. 509, 309-316
9. Donovan, A., Brownlie, A., Zhou, Y., Shepard, J., Pratt, S. J., Moynihan, J., Paw, B. H., Drejer, A., Barut, B., Zapata, A., Law, T. C., Brugnara, C., Lux, S. E., Pinkus, G. S., Pinkus, J. L., Kingsley, P. D., Palis, J., Fleming, M. D., Andrews, N. C., and Zon, L. I. (2000) Nature 403, 776-781
10. McKie, A. T., Marciani, P., Rolfs, A., Brennan, K., Wehr, K., Barrow, D., Miret, S., Bomford, A., Peters, T. J., Farzaneh, F., Hediger, M. A., Hentze, M. W., and Simpson, R. J. (2000) Mol. Cell 5, 299-309
11. Abboud, S., and Haile, D. J. (2000) J. Biol. Chem. 275, 19906-19912
12. Rouault, T. A., Hentze, M. W., Caughman, S. W., Harford, J. B., and Klausner, R. D. (1988) Science 241, 1207-1210
13. Rouault, T. A., Hentze, M. W., Haile, D. J., Harford, J. B., and Klausner, R. D. (1989) Proc. Natl. Acad. Sci. U. S. A. 86, 5768-5772
14. Guo, B., Yu, Y., and Leibold, E. A. (1994) J. Biol. Chem. 269, 24252-24260
15. Clarke, S. L., Vasanthakumar, A., Anderson, S. A., Pondarre, C., Koh, C. M., Deck, K. M., Pitula, J. S., Epstein, C. J., Fleming, M. D., and Eisenstein, R. S. (2006) EMBO J. 25, 544-553
16. Wang, J., Chen, G., Muckenthaler, M., Galy, B., Hentze, M. W., and Pantopoulos, K. (2004) Mol. Cell Biol. 24, 954-965
17. Kang, D. K., Jeong, J., Drake, S. K., Wehr, N. B., Rouault, T. A., and Levine, R. L. (2003) J. Biol. Chem. 278, 14857-14864
18. Pantopoulos, K., and Hentze, M. W. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 10559-10563
19. Hentze, M. W., and Kuhn, L. C. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 8175-8182
20. Soum, E., Brazzolotto, X., Goussias, C., Bouton, C., Moulis, J. M., Mattioli, T. A., and Drapier, J. C. (2003) Biochemistry 42, 7648-7654
21. Hanson, E. S., Foot, L. M., and Leibold, E. A. (1999) J. Biol. Chem. 274, 5047-5052
22. Brown, N. M., Anderson, S. A., Steffen, D. W., Carpenter, T. B., Kennedy, M. C., Walden, W. E., and Eisenstein, R. S. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 15235-15240
23. Fillebeen, C., Chahine, D., Caltagirone, A., Segal, P., and Pantopoulos, K. (2003) Mol. Cell Biol. 23, 6973-6981
24. Caltagirone, A., Weiss, G., and Pantopoulos, K. (2001) J. Biol. Chem. 276, 19738-19745
25. Weiss, G., Goossen, B., Doppler, W., Fuchs, D., Pantopoulos, K., Werner-Felmayer, G., Wachter, H., and Hentze, M. W. (1993) EMBO J. 12, 3651-3657
26. Phillips, J. D., Kinikini, D. V., Yu, Y., Guo, B., and Leibold, E. A. (1996) Blood 87, 2983-2992
27. Drapier, J. C., Hirling, H., Wietzerbin, J., Kaldy, P., and Kuhn, L. C. (1993) EMBO J. 12, 3643-3649
28. Richardson, D. R., Neumannova, V., Nagy, E., and Ponka, P. (1995) Blood 86, 3211-3219
29. Kim, S., and Ponka, P. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 12214-12219
30. Toth, I., Yuan, L., Rogers, J. T., Boyce, H., and Bridges, K. R. (1999) J. Biol. Chem. 274, 4467-4473
31. LaVaute, T., Smith, S., Cooperman, S., Iwai, K., Land, W., Meyron-Holtz, E., Drake, S. K., Miller, G., Abu-Asab, M., Tsokos, M., Switzer, R., III, Grinberg, A., Love, P., Tresser, N., and Rouault, T. A. (2001) Nat. Genet. 27, 209-214
32. Meyron-Holtz, E. G., Ghosh, M. C., Iwai, K., LaVaute, T., Brazzolotto, X., Berger, U. V., Land, W., Ollivierre-Wilson, H., Grinberg, A., Love, P., and Rouault, T. A. (2004) EMBO J. 23, 386-395
33. Meyron-Holtz, E. G., Ghosh, M. C., and Rouault, T. A. (2004) Science 306, 2087-2090
34. Cooperman, S. S., Meyron-Holtz, E. G., Olivierre-Wilson, H., Ghosh, M. C., McConnell, J. P., and Rouault, T. A. (2005) Blood 106, 1084-1091
35. Galy, B., Ferring, D., Minana, B., Bell, O., Janser, H. G., Muckenthaler, M., Schumann, K., and Hentze, M. W. (2005) Blood 106, 2580-2589
36. Galy, B., Holter, S. M., Klopstock, T., Ferring, D., Becker, L., Kaden, S., Wurst, W., Grone, H. J., and Hentze, M. W. (2006) Nat. Genet. 38, 967-970
37. Smith, S. R., Cooperman, S., Lavaute, T., Tresser, N., Ghosh, M., Meyron-Holtz, E., Land, W., Ollivierre, H., Jortner, B., Switzer, R., III, Messing, A., and Rouault, T. A. (2004) Ann. N. Y. Acad. Sci. 1012, 65-83
38. Imanishi, D., Yamamoto, K., Tsushima, H., Miyazaki, Y., Kuriyama, K., Tomonaga, M., and Matsuyama, T. (2000) J. Immunol. 165, 3907-3916
39. Pietsch, E. C., Chan, J. Y., Torti, F. M., and Torti, S. V. (2003) J. Biol. Chem. 278, 2361-2369
40. Leibold, E. A., and Munro, H. N. (1988) Proc. Natl. Acad. Sci. U. S. A. 85, 2171-2175
41. Roy, C. N., Blemings, K. P., Deck, K. M., Davies, P. S., Anderson, E. L., Eisenstein, R. S., and Enns, C. A. (2002) J. Cell. Physiol. 190, 218-226
42. Gross, C. N., Irrinki, A., Feder, J. N., and Enns, C. A. (1998) J. Biol. Chem. 273, 22068-22074
43. Guo, B., Phillips, J. D., Yu, Y., and Leibold, E. A. (1995) J. Biol. Chem. 270, 21645-21651
44. Philpott, C. C., Klausner, R. D., and Rouault, T. A. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 7321-7325
45. Nemeth, E., Tuttle, M. S., Powelson, J., Vaughn, M. B., Donovan, A., Ward, D. M., Ganz, T., and Kaplan, J. (2004) Science 306, 2090-2093
46. Cozzi, A., Corsi, B., Levi, S., Santambrogio, P., Albertini, A., and Arosio, P. (2000) J. Biol. Chem. 275, 25122-25129
47. Muckenthaler, M., Richter, A., Gunkel, N., Riedel, D., Polycarpou-Schwarz, M., Hentze, S., Falkenhahn, M., Stremmel, W., Ansorge, W., and Hentze, M. W. (2003) Blood 101, 3690-3698
48. Cozzi, A., Corsi, B., Levi, S., Santambrogio, P., Biasiotto, G., and Arosio, P. (2004) Blood 103, 2377-2383
49. Guo, B., Brown, F. M., Phillips, J. D., Yu, Y., and Leibold, E. A. (1995) J. Biol. Chem. 270, 16529-16535
50. Orino, K., Lehman, L., Tsuji, Y., Ayaki, H., Torti, S. V., and Torti, F. M. (2001) Biochem. J. 357, 241-247
51. Kim, H. Y., Klausner, R. D., and Rouault, T. A. (1995) J. Biol. Chem. 270, 4983-4986
52. Popovic, Z., and Templeton, D. M. (2005) Mol. Cell Biochem. 268, 67-74
53. Lin, E., Graziano, J. H., and Freyer, G. A. (2001) J. Biol. Chem. 276, 27685-27692