A Specific Role of the Yeast Mitochondrial Carriers Mrs3/4p in Mitochondrial Iron Acquisition under Iron-limiting Conditions

Journal of Biological Chemistry

Volumn 278, Issue 42, 2003, Pages 40612-40620

  Mühlenhoff, Ulrich ^a   Stadler, Jochen A ^b   Richhardt, Nadine ^a   Seubert, Andreas ^a   Eickhorst, Thomas ^a   Schweyen, Rudolf J ^b   Lill, Roland ^a   Wiesenberger, Gerlinde ^b  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

^b UNIVERSITY OF VIENNA   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHESIS; CYTOLOGY; IRON; PROTEINS; YEAST;

MITOCHONDRIA;

GENES;

CARRIER PROTEIN; HEME; IRON; IRON SULFUR PROTEIN; PROTEIN MRS3; PROTEIN MRS4P; UNCLASSIFIED DRUG;

ARTICLE; BIOSYNTHESIS; CELL GROWTH; CONTROLLED STUDY; FUNGAL GENE; GENE CONTROL; GENE EXPRESSION; GENE FUNCTION; GENE OVEREXPRESSION; GENE SEQUENCE; GENETIC CODE; GENOME; IN VIVO STUDY; IRON METABOLISM; IRON TRANSPORT; ISOTOPE LABELING; MITOCHONDRION; MULTIGENE FAMILY; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN SYNTHESIS; REGULON; UPREGULATION; YEAST;

ADENOSINE TRIPHOSPHATE; BLOTTING, NORTHERN; CARRIER PROTEINS; CATION TRANSPORT PROTEINS; CYTOSOL; GENE DELETION; GENOME, FUNGAL; HEME; INTRACELLULAR MEMBRANES; IRON; MEMBRANE POTENTIALS; MITOCHONDRIA; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PLASMIDS; REPRESSOR PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; UP-REGULATION;

EID: 17044451174     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M307847200     Document Type: Article

References (72)

1. Aquila, H., Link, T. A., and Klingenberg, M. (1985) EMBO J. 4, 2369-2376
2. Walker, J. E. (1992) Curr. Opin. Struct. Biol. 2, 519-526
3. Palmieri, F. (1994) FEBS Lett. 346, 48-54
4. Palmieri, L., Rottensteiner, H., Girzalsky, W., Scarcia, P., Palmieri, F., and Erdmann, R. (2001) EMBO J. 20, 5049-5059
5. El Moualij, B., Duyckaerts, C., Lamotte-Brasseur, J., and Sluse, F. E. (1997) Yeast 13, 573-581
6. Belenkiy, R., Haefele, A., Eisen, M. B., and Wohlrab, H. (2000) Biochim. Biophys. Acta 1467, 207-218
7. Palmieri, L., Runswick, M. J., Fiermonte, G., Walker, J. E., and Palmieri, F. (2000) J. Bioenerg. Biomembr. 32, 67-77
8. Wohlrab, H., and Briggs, C. (1994) Biochemistry 33, 9371-9375
9. Palmieri, L., De Marco, V., Iacobazzi, V., Palmieri, F., Runswick, M. J., and Walker, J. E. (1997) FEBS Lett. 410, 447-451
10. Palmieri, L., Agrimi, G., Runswick, M. J., Fearnley, I. M., Palmieri, F., and Walker, J. E. (2001) J. Biol. Chem. 276, 1916-1922
11. Palmieri, L., Lasorsa, F. M., De Palma, A., Palmieri, F., Runswick, M. J., and Walker, J. E. (1997) FEBS Lett. 417, 114-118
12. Marobbio, C. M., Vozza, A., Harding, M., Bisaccia, F., Palmieri, F., and Walker, J. E. (2002) EMBO J. 21, 5653-5661
13. Tzagoloff, A., Jang, J., Glerum, D. M., and Wu, M. (1996) J. Biol. Chem. 271, 7392-7397
14. Prohl, C., Pelzer, W., Diekert, K., Kmita, H., Bedekovics, T. Kispal, G., and Lill, R. (2001) Mol. Cell. Biol. 21, 1089-1097
15. Wiesenberger, G., Link, T. A., von Ahsen, U., Waldherr, M., and Schweyen, R. J. (1991) J. Mol. Biol. 217, 23-37
16. Van Dyck, E., Jank, B., Ragnini, A., Schweyen, R. J., Duyckaerts, C., Sluse, F., and Foury, F. (1995) Mol. Gen. Genet. 246, 426-436
17. Kao, L. R., Megraw, T. L., and Chae, C. B. (1996) Yeast 12, 1239-1250
18. Cho, J. H., Ha, S. J., Kao, L. R., Megraw, T. L., and Chae, C. B. (1998) Mol. Cell. Biol. 18, 5712-5723
19. Lalo, D., Stettler, S., Mariotte, S., Gendreau, E., and Thuriaux, P. (1994) Yeast 10, 523-533
20. Winzeler, E. A., Shoemaker, D. D., Astromoff, A., Liang, H., Anderson, K. Andre, B., Bangham, R., Benito, R., Boeke, J. D., Bussey, H., Chu, A. M., Connelly, C., Davis, K., Dietrich, F., Dow, S. W., El Bakkoury, M., Foury, F., Friend, S. H., Gentalen, E., Giaever, G., Hegemann, J. H., Jones, T., Laub, M., Liao, H., Davis, R. W., et al. (1999) Science 285, 901-906
21. Waldherr, M., Ragnini, A., Jank, B., Teply, R., Wiesenberger, G., and Schweyen, R. J. (1993) Curr. Genet. 24, 301-306
22. Bui, D. M., Gregan, J., Jarosch, E., Ragnini, A., and Schweyen, R. J. (1999) J. Biol. Chem. 274, 20438-20443
23. Kolisek, M., Zsurka, G., Samaj, J., Weghuber, J., Schweyen, R. J., and Schweigel, M. (2003) EMBO J. 22, 1235-1244
24. Rutherford, J. C., Jaron, S., Ray, E., Brown, P. O., and Winge, D. R. (2001) Proc. Natl. Acad. Sci. U. S. A. 98, 14322-14327
25. Foury, F., and Roganti, T. (2002) J. Biol. Chem. 277, 24475-24483
26. Yamaguchi-Iwai, Y., Stearman, R., Dancis, A., and Klausner, R. D. (1996) EMBO J. 15, 3377-3384
27. Casas, C., Aldea, M., Espinet, C., Gallego, C., Gil, R., and Herrero, E. (1997) Yeast 13, 621-637
28. Yamaguchi-Iwai, Y., Ueta, R., Fukunaka, A., and Sasaki, R. (2002) J. Biol. Chem. 277, 18914-18918
29. Stadler, J. A., and Schweyen, R. J. (2002) J. Biol. Chem. 277, 39649-39654
30. Lange, H., Kispal, G., and Lill, R. (1999) J. Biol. Chem. 274, 18989-18996
31. Mühlenhoff, U., Richhardt, N., Gerber, J., and Lill, R. (2002) J. Biol. Chem. 277, 29810-29816
32. Zollner, A., Rödel, G., and Haid, A. (1992) Eur. J. Biochem. 207, 1093-1100
33. Wach, A., Brachat, A., Rebischung, C., Steiner, S., Pokorni, K., te Heesen, S. and Philippsen, P. (1998) in Methods in Microbiology (Brown, A., and Tuite, M., eds) Vol. 26, pp. 67-81, Academic Press, San Diego, CA
34. Sherman, F. (1991) Methods Enzymol. 194, 3-21
35. Daum, G., Böhni, P. C., and Schatz, G. (1982) J. Biol. Chem. 257, 13028-13033
36. Vernet, T., Dignard, D., and Thomas, D. Y. (1987) Gene (Amst.) 52, 225-233
37. Ammerer, G. (1983) Methods Enzymol. 101, 192-201
38. Ausubel, F. M., Brent, R., Kingston, R. E., Moore, D. D., Seidman, J. G., Smith, J. A., and Struhl, K. (eds) (1993) Current Protocols in Molecular Biology, John Wiley and Sons, Boston
39. Kispal, G., Csere, P., Prohl, C., and Lill, R. (1999) EMBO J. 18, 3981-3989
40. Lange, H., Kispal, G., Kaut, A., and Lill, R. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 1050-1055
41. Lange, H., Lisowsky, T., Gerber, J., Mühlenhoff, U., Kispal, G., and Lill, R. (2001) EMBO Rep. 2, 715-720
42. Mühlenhoff, U., Richhardt, N., Ristow, M., Kispal, G., and Lill, R. (2002) Hum. Mol. Genet. 11, 2025-2036
43. Mühlenhoff, U., Richhardt, N., Gerber, J., and Lill, R. (2003) EMBO J. 22, in press
44. Mumberg, D., Müller, R., and Funk, M. (1995) Gene (Amst.) 156, 119-122
45. Scaduto, R. C., and Grotyohann, L. W. (1999) Biophys. J. 76, 469-477
46. Sambrook, J., and Russell, D. W. (2001) Molecular Cloning: A Laboratory Manual, 3rd Ed., Cold Spring Harbor Press, Cold Spring Harbor, NY
47. Gietz, D., St. Jean, A., Woods, R. A., and Schiestl, R. H. (1992) Nucleic Acids Res. 20, 1425
48. Woontner, M., and Jaehning, J. A. (1990) J. Biol. Chem. 265, 8979-8982
49. Harlow, E., and Lane, D. (1988) Antibodies: A Laboratory Manual, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
50. Kispal, G., Csere, P., Guiard, B., and Lill, R. (1997) FEBS Lett. 418, 346-350
51. Kispal, G., Rosenkrantz, M., Guarente, L., and Srere, P. A. (1988) J. Biol. Chem. 263, 11145-11149
52. Robinson, K. M., von Kieckebusch-Guck, A., and Lemire, B. D. (1991) J. Biol. Chem. 266, 21347-21350
53. Robinson, K. M., and Lemire, B. D. (1995) Methods Enzymol. 260, 34-51
54. Li, J., Kogan, M., Knight, S. A., Pain, D., and Dancis, A. (1999) J. Biol. Chem. 274, 33025-33034
55. Askwith, C., Eide, D., Van Ho, A., Bernard, P. S., Li, L., Davis-Kaplan, S., Sipe, D. M., and Kaplan, J. (1994) Cell 76, 403-410
56. Stearman, R., Yuan, D. S., Yamaguchi-Iwai, Y., Klausner, R. D., and Dancis, A. (1996) Science 271, 1552-1557
57. Heymann, P., Ernst, J. F., and Winkelmann, G. (1999) Biometals 12, 301-306
58. Heymann, P., Ernst, J. F., and Winkelmann, G. (2000) Biometals 13, 65-72
59. Heymann, P., Ernst, J. F., and Winkelmann, G. (2000) FEMS Microbiol. Lett. 186, 221-227
60. Protchenko, O., Ferea, T., Rashford, J., Tiedeman, J., Brown, P. O., Botstein, D., and Philpott, C. C. (2001) J. Biol. Chem. 276, 49244-49250
61. Labbe-Bois, R., and Camadro, J. M. (1994) in Metal Ions in Fungi (Winkelmann, G., and Winge, D. R., eds) pp. 413-453, Marcel Dekker Inc., New York
62. Gerber, J., Mühlenhoff, U., and Lill, R. (2003) EMBO Rep. 4, 906-911
63. Rutherford, J. C., Jaron, S., and Winge, D. R. (2003) J. Biol. Chem. 278, 27636-27643
64. Babcock, M., De Silva, D., Oaks, R., Davis-Kaplan, S., Jiralerspong, S., Montermini, L., Pandolfo, M., and Kaplan, J. (1997) Science 276, 1709-1712
65. Lill, R., and Kispal, G. (2000) Trends Biochem. Sci. 25, 352-356
66. Gregan, J., Kolisek, M., and Schweyen, R. J. (2001) Genes Dev. 15, 2229-2237
67. Luk, E. E., and Culotta, V. C. (2001) J. Biol. Chem. 276, 47556-47562
68. Gerber, J., and Lill, R. (2002) Mitochondrion 2, 71-86
69. Foury, F., and Talibi, D. (2001) J. Biol. Chem. 276, 7762-7768
70. Eide, D. J. (1998) Annu. Rev. Nutr. 18, 441-469
71. Van Ho, A., Ward, D., and Kaplan, J. (2002) Annu. Rev. Microbiol. 56, 237-261
72. Nyhus, K., Ozaki, L., and Jacobson, E. S. (2002) Med. Mycol. 40, 581-591