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Volumn 105, Issue 4, 2005, Pages 1797-1802

Hepcidin excess induces the sequestration of iron and exacerbates tumor-associated anemia

Author keywords

[No Author keywords available]

Indexed keywords

FERRIC FERROCYANIDE; HEPCIDIN; IRON;

EID: 13544252463     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood-2004-08-3375     Document Type: Article
Times cited : (163)

References (24)
  • 1
    • 1842577545 scopus 로고    scopus 로고
    • Prevalence and outcomes of anemia in cancer, a systematic review of the literature
    • Knight K, Wade S, Balducci L. Prevalence and outcomes of anemia in cancer, a systematic review of the literature. Am J Med. 2004;116(suppl 7A):11S-26S.
    • (2004) Am J Med , vol.116 , Issue.SUPPL. 7A
    • Knight, K.1    Wade, S.2    Balducci, L.3
  • 2
    • 9144245515 scopus 로고    scopus 로고
    • The CRIT Study: Anemia and blood transfusion in the critically ill-current clinical practice in the United States
    • Corwin HL, Gettinger A, Pearl RG, et al. The CRIT Study: anemia and blood transfusion in the critically ill-current clinical practice in the United States. Crit Care Med. 2004;32:39-52.
    • (2004) Crit Care Med , vol.32 , pp. 39-52
    • Corwin, H.L.1    Gettinger, A.2    Pearl, R.G.3
  • 3
    • 0030841393 scopus 로고    scopus 로고
    • Iron, infections, and anemia of inflammation
    • Jurado RL. Iron, infections, and anemia of inflammation. Clin Infect Dis. 1997;25:888-895.
    • (1997) Clin Infect Dis , vol.25 , pp. 888-895
    • Jurado, R.L.1
  • 4
    • 0013954846 scopus 로고
    • The anemia of chronic disorders
    • Cartwright GE. The anemia of chronic disorders. Semin Hematol. 1966;3:351-375.
    • (1966) Semin Hematol , vol.3 , pp. 351-375
    • Cartwright, G.E.1
  • 5
    • 0033162263 scopus 로고    scopus 로고
    • Advances in the anemia of chronic disease
    • Means RT Jr. Advances in the anemia of chronic disease. Int J Hematol. 1999;70:7-12.
    • (1999) Int J Hematol , vol.70 , pp. 7-12
    • Means Jr., R.T.1
  • 6
    • 0041672570 scopus 로고    scopus 로고
    • Hepcidin, a key regulator of iron metabolism and mediator of anemia of inflammation
    • Ganz T. Hepcidin, a key regulator of iron metabolism and mediator of anemia of inflammation. Blood. 2003;102:783-788.
    • (2003) Blood , vol.102 , pp. 783-788
    • Ganz, T.1
  • 7
    • 0038662619 scopus 로고    scopus 로고
    • Hepcidin, a putative mediator of anemia of inflammation, is a type II acute-phase protein
    • Nemeth E, Valore EV, Territo M, et al. Hepcidin, a putative mediator of anemia of inflammation, is a type II acute-phase protein. Blood. 2003;101:2461-2463.
    • (2003) Blood , vol.101 , pp. 2461-2463
    • Nemeth, E.1    Valore, E.V.2    Territo, M.3
  • 8
    • 2342510407 scopus 로고    scopus 로고
    • IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin
    • Nemeth E, Rivera S, Gabayan V, et al. IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin. J Clin Invest. 2004;113:1271-1276.
    • (2004) J Clin Invest , vol.113 , pp. 1271-1276
    • Nemeth, E.1    Rivera, S.2    Gabayan, V.3
  • 9
    • 0037007064 scopus 로고    scopus 로고
    • Severe iron deficiency anemia in transgenic mice expressing liver hepcidin
    • Nicolas G, Bennoun M, Porteu A, et al. Severe iron deficiency anemia in transgenic mice expressing liver hepcidin. Proc Natl Acad Sci USA. 2002;99:4596-4601.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 4596-4601
    • Nicolas, G.1    Bennoun, M.2    Porteu, A.3
  • 10
    • 0037111732 scopus 로고    scopus 로고
    • Inappropriate expression of hepcidin is associated with iron refractory anemia: Implications for the anemia of chronic disease
    • Weinstein DA, Roy CN, Fleming MD, Loda MF, Wolfsdorf JI, Andrews NC. Inappropriate expression of hepcidin is associated with iron refractory anemia: implications for the anemia of chronic disease. Blood. 2002;100:3776-3781.
    • (2002) Blood , vol.100 , pp. 3776-3781
    • Weinstein, D.A.1    Roy, C.N.2    Fleming, M.D.3    Loda, M.F.4    Wolfsdorf, J.I.5    Andrews, N.C.6
  • 11
    • 0036791486 scopus 로고    scopus 로고
    • The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation
    • Nicolas G, Chauvet C, Viatte L, et al. The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation. J Clin Invest. 2002;110:1037-1044.
    • (2002) J Clin Invest , vol.110 , pp. 1037-1044
    • Nicolas, G.1    Chauvet, C.2    Viatte, L.3
  • 12
    • 0036670737 scopus 로고    scopus 로고
    • Relationship between intestinal iron-transporter expression, hepatic hepcidin levels and the control of iron absorption
    • Anderson GJ, Frazer DM, Wilkins SJ, et al. Relationship between intestinal iron-transporter expression, hepatic hepcidin levels and the control of iron absorption. Biochem Soc Trans. 2002;30:724-726.
    • (2002) Biochem Soc Trans , vol.30 , pp. 724-726
    • Anderson, G.J.1    Frazer, D.M.2    Wilkins, S.J.3
  • 13
    • 2442426523 scopus 로고    scopus 로고
    • An Hfe-dependent pathway mediates hyposideremia in response to lipopolysaccharide-induced inflammation in mice
    • Roy CN, Custodio AO, de Graaf J, et al. An Hfe-dependent pathway mediates hyposideremia in response to lipopolysaccharide-induced inflammation in mice. Nat Genet. 2004;36:481-485.
    • (2004) Nat Genet , vol.36 , pp. 481-485
    • Roy, C.N.1    Custodio, A.O.2    De Graaf, J.3
  • 14
    • 0035896642 scopus 로고    scopus 로고
    • Hepcidin, a urinary antimicrobial peptide synthesized in the liver
    • Park CH, Valore EV, Waring AJ, Ganz T. Hepcidin, a urinary antimicrobial peptide synthesized in the liver. J Biol Chem. 2001;276:7806-7810.
    • (2001) J Biol Chem , vol.276 , pp. 7806-7810
    • Park, C.H.1    Valore, E.V.2    Waring, A.J.3    Ganz, T.4
  • 16
    • 0015228412 scopus 로고
    • Measurement of liver-iron concentration in needle-biopsy specimens
    • Barry M, Sherlock S. Measurement of liver-iron concentration in needle-biopsy specimens. Lancet. 1971;1:100-103.
    • (1971) Lancet , vol.1 , pp. 100-103
    • Barry, M.1    Sherlock, S.2
  • 17
    • 0037020241 scopus 로고    scopus 로고
    • The solution structure of human hepcidin, a peptide hormone with antimicrobial activity that is involved in iron uptake and hereditary hemochromatosis
    • Hunter HN, Fulton DB, Ganz T Vogel HJ. The solution structure of human hepcidin, a peptide hormone with antimicrobial activity that is involved in iron uptake and hereditary hemochromatosis. J Biol Chem. 2002;277:37597-37603.
    • (2002) J Biol Chem , vol.277 , pp. 37597-37603
    • Hunter, H.N.1    Fulton, D.B.2    Ganz, T.3    Vogel, H.J.4
  • 18
    • 0016379537 scopus 로고
    • Bone marrow erythropoiesis in the anemia of infection, inflammation, and malignancy
    • Zucker S, Friedman S, Lysik RM. Bone marrow erythropoiesis in the anemia of infection, inflammation, and malignancy. J Clin Invest. 1974;53:1132-1138.
    • (1974) J Clin Invest , vol.53 , pp. 1132-1138
    • Zucker, S.1    Friedman, S.2    Lysik, R.M.3
  • 19
    • 0028869986 scopus 로고
    • Multiple defects in innate and adaptive immunologic function in NOD/LtSz-scid mice
    • Shultz LD, Schweitzer PA, Christianson SW, et al. Multiple defects in innate and adaptive immunologic function in NOD/LtSz-scid mice. J Immunol. 1995;154:180-191.
    • (1995) J Immunol , vol.154 , pp. 180-191
    • Shultz, L.D.1    Schweitzer, P.A.2    Christianson, S.W.3
  • 20
    • 1842447427 scopus 로고    scopus 로고
    • Anemia of chronic disease
    • Beutler E, Lichtman MA, Coller BS, Kipps TJ, Seligsohn U, eds. New York, NY: McGraw-Hill Inc;
    • Erslev AJ. Anemia of chronic disease. In: Beutler E, Lichtman MA, Coller BS, Kipps TJ, Seligsohn U, eds. Williams Hematology. New York, NY: McGraw-Hill Inc; 1999:481-488.
    • (1999) Williams Hematology , pp. 481-488
    • Erslev, A.J.1
  • 21
    • 0024590195 scopus 로고
    • Protracted anemia associated with chronic, relapsing systemic inflammation induced by arthropathic peptidoglycan-polysaccharide polymers in rats
    • Sartor RB, Anderle SK, Rifai N, et al. Protracted anemia associated with chronic, relapsing systemic inflammation induced by arthropathic peptidoglycan-polysaccharide polymers in rats. Infect Immun. 1989;57:1177-1185.
    • (1989) Infect Immun , vol.57 , pp. 1177-1185
    • Sartor, R.B.1    Anderle, S.K.2    Rifai, N.3
  • 22
    • 0017579676 scopus 로고
    • The anaemia of chronic disorders: Studies of iron reutilization in the anaemia of experimental malignancy and chronic inflammation
    • Zarrabi MH, Lysik R, DiStefano J, Zucker S. The anaemia of chronic disorders: studies of iron reutilization in the anaemia of experimental malignancy and chronic inflammation. Br J Haematol. 1977;35:647-658.
    • (1977) Br J Haematol , vol.35 , pp. 647-658
    • Zarrabi, M.H.1    Lysik, R.2    DiStefano, J.3    Zucker, S.4
  • 24
    • 1642302853 scopus 로고    scopus 로고
    • Contributions of beta2-microglobulin-dependent molecules and lymphocytes to iron regulation: Insights from HfeRag1(-/-) and beta2mRag1(-/-) double knock-out mice
    • Miranda CJ, Makui H, Andrews NC, Santos MM. Contributions of beta2-microglobulin-dependent molecules and lymphocytes to iron regulation: insights from HfeRag1(-/-) and beta2mRag1(-/-) double knock-out mice. Blood. 2004;103:2847-2849.
    • (2004) Blood , vol.103 , pp. 2847-2849
    • Miranda, C.J.1    Makui, H.2    Andrews, N.C.3    Santos, M.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.