-
1
-
-
2042546096
-
Balancing acts: Molecular control of mammalian iron metabolism
-
Hentze, M.W., Muckenthaler, M.U., and Andrews, N.C. 2004. Balancing acts: molecular control of mammalian iron metabolism [review]. Cell. 117:285-297.
-
(2004)
Cell
, vol.117
, pp. 285-297
-
-
Hentze, M.W.1
Muckenthaler, M.U.2
Andrews, N.C.3
-
2
-
-
0034022636
-
The gene TFR2 is mutated in a new type of haemochromatosis mapping to 7q22
-
Camaschella, C., et al. 2000. The gene TFR2 is mutated in a new type of haemochromatosis mapping to 7q22. Nat. Genet. 25:14-15.
-
(2000)
Nat. Genet.
, vol.25
, pp. 14-15
-
-
Camaschella, C.1
-
3
-
-
9344224529
-
A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis
-
Feder, J.N., et al. 1996. A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis. Nat. Genet. 13:399-408.
-
(1996)
Nat. Genet.
, vol.13
, pp. 399-408
-
-
Feder, J.N.1
-
4
-
-
17944380796
-
Autosomal-dominant hemochromatosis is associated with a mutation in the ferroportin (SLC11A3) gene
-
doi:10.1172/JCI200113468
-
Montosi, G., et al. 2001. Autosomal-dominant hemochromatosis is associated with a mutation in the ferroportin (SLC11A3) gene. J. Clin. Invest. 108:619-623. doi:10.1172/JCI200113468.
-
(2001)
J. Clin. Invest.
, vol.108
, pp. 619-623
-
-
Montosi, G.1
-
5
-
-
0034930197
-
A mutation in SLC11A3 is associated with autosomal dominant hemochromatosis
-
Njajou, O.T., et al. 2001. A mutation in SLC11A3 is associated with autosomal dominant hemochromatosis. Nat. Genet. 28:213-214.
-
(2001)
Nat. Genet.
, vol.28
, pp. 213-214
-
-
Njajou, O.T.1
-
6
-
-
9144252017
-
Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis
-
Papanikolaou, G., et al. 2004. Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis, Nat. Genet. 36:77-82.
-
(2004)
Nat. Genet.
, vol.36
, pp. 77-82
-
-
Papanikolaou, G.1
-
7
-
-
20244388240
-
Mutant antimicrobial peptide hepcidin is associated with severe juvenile hemochromatosis
-
Roetto, A., et al. 2003. Mutant antimicrobial peptide hepcidin is associated with severe juvenile hemochromatosis. Nat. Genet. 33:21-22.
-
(2003)
Nat. Genet.
, vol.33
, pp. 21-22
-
-
Roetto, A.1
-
8
-
-
0037460697
-
Disrupted hepcidin regulation in HFE-associated haemochromatosis and the liver as a regulator of body iron homoeostasis
-
Bridle, K.R., et al. 2003. Disrupted hepcidin regulation in HFE-associated haemochromatosis and the liver as a regulator of body iron homoeostasis. Lancet. 361:669-673,
-
(2003)
Lancet
, vol.361
, pp. 669-673
-
-
Bridle, K.R.1
-
9
-
-
13544250486
-
Hepcidin is decreased in TFR2 hemochromatosis
-
Nemeth, E., Roetto, A., Garozzo, G., Ganz., T., and Camaschella, C. 2005. Hepcidin is decreased in TFR2 hemochromatosis. Blood. 105:1803-1806.
-
(2005)
Blood
, vol.105
, pp. 1803-1806
-
-
Nemeth, E.1
Roetto, A.2
Garozzo, G.3
Ganz, T.4
Camaschella, C.5
-
10
-
-
0035902605
-
Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice
-
Nicolas, G., et al. 2001. Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice. Proc. Natl. Acad. Sci. U. S. A. 98:8780-8785.
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 8780-8785
-
-
Nicolas, G.1
-
11
-
-
20444413054
-
Deregulation of proteins involved in iron metabolism in hepcidin-deficient mice
-
doi:10.1182/blood-2004-12-4608
-
Viatte, L., et al. 2005. Deregulation of proteins involved in iron metabolism in hepcidin-deficient mice. Blood. doi:10.1182/blood-2004-12-4608.
-
(2005)
Blood
-
-
Viatte, L.1
-
12
-
-
0037007064
-
Severe iron deficiency anemia in transgenic mice expressing liver hepcidin
-
Nicolas, G., et al. 2002. Severe iron deficiency anemia in transgenic mice expressing liver hepcidin. Proc. Natl. Acad. Sci. U. S. A. 99:4596-4601.
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 4596-4601
-
-
Nicolas, G.1
-
13
-
-
10844258104
-
Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization
-
Nemeth, E., et al. 2004. Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization. Science. 306:2090-2093.
-
(2004)
Science
, vol.306
, pp. 2090-2093
-
-
Nemeth, E.1
-
14
-
-
20444416123
-
The iron exporter ferroportin (Slc40a1) is essential for iron homeostasis
-
Donovan, A., et al. 2005. The iron exporter ferroportin (Slc40a1) is essential for iron homeostasis. Cell Metabolism. 1:191-200.
-
(2005)
Cell Metabolism
, vol.1
, pp. 191-200
-
-
Donovan, A.1
-
15
-
-
11144358032
-
The repulsive guidance molecule RGMa is involved in the formation of afferent connections in the dentate gyrus
-
Brinks, H., et al. 2004. The repulsive guidance molecule RGMa is involved in the formation of afferent connections in the dentate gyrus. J. Neurosci. 24:3862-3869.
-
(2004)
J. Neurosci.
, vol.24
, pp. 3862-3869
-
-
Brinks, H.1
-
16
-
-
4143080506
-
RGM and its receptor neogenin regulate neuronal survival
-
Matsunaga, E., et al. 2004. RGM and its receptor neogenin regulate neuronal survival. Nat. Cell Biol. 6:749-755.
-
(2004)
Nat. Cell Biol.
, vol.6
, pp. 749-755
-
-
Matsunaga, E.1
-
17
-
-
18544379947
-
RGM is a repulsive guidance molecule for retinal axons
-
Monnier, P.P., et al. 2002. RGM is a repulsive guidance molecule for retinal axons. Nature. 419:392-395.
-
(2002)
Nature
, vol.419
, pp. 392-395
-
-
Monnier, P.P.1
-
18
-
-
0742322861
-
Repulsive guidance molecule (RGM) gene function is required for neural tube closure but not retinal topography in the mouse visual system
-
IS. Niederkofler, V., Salie, R., Sigrist, M., and Arber, S. 2004. Repulsive guidance molecule (RGM) gene function is required for neural tube closure but not retinal topography in the mouse visual system. J. Neurosci. 24:808-818.
-
(2004)
J. Neurosci.
, vol.24
, pp. 808-818
-
-
Niederkofler, V.1
Salie, R.2
Sigrist, M.3
Arber, S.4
-
19
-
-
10744228029
-
DRAGON: A member of the repulsive guidance molecule-related family of neuronal- and muscle-expressed membrane proteins is regulated by DRG11 and has neuronal adhesive properties
-
Samad, T.A., et al. 2004. DRAGON: a member of the repulsive guidance molecule-related family of neuronal- and muscle-expressed membrane proteins is regulated by DRG11 and has neuronal adhesive properties. J. Neurosci. 24:2027-2036.
-
(2004)
J. Neurosci.
, vol.24
, pp. 2027-2036
-
-
Samad, T.A.1
-
20
-
-
10444271668
-
Hepatic and extrahepatic expression of the new iron regulatory protein hemojuvelin
-
Rodriguez Martinez, A., Niemela, O., and Parkkila, S. 2004. Hepatic and extrahepatic expression of the new iron regulatory protein hemojuvelin. Haematologica. 89:1441-1445.
-
(2004)
Haematologica
, vol.89
, pp. 1441-1445
-
-
Rodriguez Martinez, A.1
Niemela, O.2
Parkkila, S.3
-
21
-
-
2542468736
-
Spectrum of hemojuvelin gene mutations in 1q-linked juvenile hemochromatosis
-
Lanzara, C., et al. 2004. Spectrum of hemojuvelin gene mutations in 1q-linked juvenile hemochromatosis. Blood. 103:4317-4321.
-
(2004)
Blood
, vol.103
, pp. 4317-4321
-
-
Lanzara, C.1
-
22
-
-
0033168767
-
The C282Y mutation causing hereditary hemochromatosis does not produce a null allele
-
Levy, J.E., Montross, L.K., Cohen, D.E., Fleming, M.D., and Andrews, N.C. 1999. The C282Y mutation causing hereditary hemochromatosis does not produce a null allele. Blood. 94:9-11.
-
(1999)
Blood
, vol.94
, pp. 9-11
-
-
Levy, J.E.1
Montross, L.K.2
Cohen, D.E.3
Fleming, M.D.4
Andrews, N.C.5
-
23
-
-
0034062537
-
Genes chat modify the hemochromatosis phenotype in mice
-
Levy, J.E., Montross, L.K., and Andrews, N.C. 2000. Genes chat modify the hemochromatosis phenotype in mice. J. Clin. Invest. 105:1209-1216.
-
(2000)
J. Clin. Invest.
, vol.105
, pp. 1209-1216
-
-
Levy, J.E.1
Montross, L.K.2
Andrews, N.C.3
-
24
-
-
0032959574
-
Transferrin receptor is necessary for development of erythrocytes and the nervous system
-
Levy, J.E., Jin, O., Fujiwara, Y., Kuo, F., and Andrews, N.C. 1999. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Nat. Genet. 21:396-399,
-
(1999)
Nat. Genet.
, vol.21
, pp. 396-399
-
-
Levy, J.E.1
Jin, O.2
Fujiwara, Y.3
Kuo, F.4
Andrews, N.C.5
-
25
-
-
0034254752
-
The molecular defect in hypotransferrinemic mice
-
Trenor, C.C., 3rd, Campagna, D.R., Sellers, V.M., Andrews, N.C., and Fleming, M.D. 2000. The molecular defect in hypotransferrinemic mice. Blood. 96:1113-1118.
-
(2000)
Blood
, vol.96
, pp. 1113-1118
-
-
Trenor III, C.C.1
Campagna, D.R.2
Sellers, V.M.3
Andrews, N.C.4
Fleming, M.D.5
-
26
-
-
0038025679
-
Comparative analysis of mouse hepcidin 1 and 2 genes: Evidence for different patterns of expression and co-inducibility during iron overload
-
Ilyin, G., et al. 2003. Comparative analysis of mouse hepcidin 1 and 2 genes: evidence for different patterns of expression and co-inducibility during iron overload. FEBS Lett. 542:22-26.
-
(2003)
FEBS Lett.
, vol.542
, pp. 22-26
-
-
Ilyin, G.1
-
27
-
-
20844462571
-
In vitro functional analysis of human ferroportin (FPN) and hemochromatosis-associated FPN mutations
-
Schimanski, L.M., et al. 2005. In vitro functional analysis of human ferroportin (FPN) and hemochromatosis-associated FPN mutations. Blood. 105:4096-5102.
-
(2005)
Blood
, vol.105
, pp. 4096-5102
-
-
Schimanski, L.M.1
-
28
-
-
0037100382
-
Autosomal dominant reticuloendothelial iron overload associated with a 3-base pair deletion in the ferroportin 1 gene (SLC11A3)
-
Devalia, V., et al. 2002. Autosomal dominant reticuloendothelial iron overload associated with a 3-base pair deletion in the ferroportin 1 gene (SLC11A3). Blood. 100:695-697.
-
(2002)
Blood
, vol.100
, pp. 695-697
-
-
Devalia, V.1
-
29
-
-
0037622887
-
A novel mutation in ferroportin1 is associated with haemochromatosis in a Solomon Islands patient
-
Arden, K.E., et al. 2003. A novel mutation in ferroportin1 is associated with haemochromatosis in a Solomon Islands patient. Gut. 52:1215-1217
-
(2003)
Gut
, vol.52
, pp. 1215-1217
-
-
Arden, K.E.1
-
30
-
-
0242724167
-
Dominant hemochromatosis due to N144H mutation of SLC11A3: Clinical and biological characreristics
-
Njajou, O.T., et al. 2002. Dominant hemochromatosis due to N144H mutation of SLC11A3: clinical and biological characreristics. Blood Cells Mol. Dis. 29:439-443.
-
(2002)
Blood Cells Mol. Dis.
, vol.29
, pp. 439-443
-
-
Njajou, O.T.1
-
31
-
-
2642646258
-
Mouse mutant embryos lacking huntingtin are rescued from lethality by wild-type extraembryonic tissues
-
Dragatsis, I., Efsrratiadis, A., and Zeitlin, S. 1998. Mouse mutant embryos lacking huntingtin are rescued from lethality by wild-type extraembryonic tissues. Development. 125:1529-1539.
-
(1998)
Development
, vol.125
, pp. 1529-1539
-
-
Dragatsis, I.1
Efsrratiadis, A.2
Zeitlin, S.3
-
32
-
-
0034677467
-
Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter
-
Donovan, A., et al. 2000. Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter. Nature. 403:776-781.
-
(2000)
Nature
, vol.403
, pp. 776-781
-
-
Donovan, A.1
|