Elucidation of the mechanism of mitochondrial iron loading in Friedreich's ataxia by analysis of a mouse mutant

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 38, 2009, Pages 16381-16386

  Huang, Michael Li Hsuan ^a   Becker, Erika M ^a   Whitnall, Megan ^a   Rahmanto, Yohan Suryo ^a   Ponka, Prem ^b   Richardson, Des R ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

^b MCGILL UNIVERSITY   (Canada)

Author keywords

Frataxin; Heme synthesis; Iron transferrin

Indexed keywords

CD71 ANTIGEN; COPROPORPHYRINOGEN OXIDASE; CREATINE KINASE MM; FERRITIN; FERROCHELATASE; FERROPORTIN 1; FRATAXIN; HEME OXYGENASE 1; HEPCIDIN; IRON SULFUR PROTEIN; MEMBRANE PROTEIN; PORPHOBILINOGEN DEAMINASE; PORPHOBILINOGEN SYNTHASE; PROTEIN SEC1; PROTEIN SEC15; TRANSFERRIN; UNCLASSIFIED DRUG; UROPORPHYRINOGEN III SYNTHASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; FRIEDREICH ATAXIA; HEME SYNTHESIS; IRON DEFICIENCY; IRON METABOLISM; IRON TRANSPORT; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; UPREGULATION;

ANIMALS; ANTIMICROBIAL CATIONIC PEPTIDES; BLOTTING, WESTERN; CARBON-SULFUR LYASES; COPROPORPHYRINOGEN OXIDASE; DISEASE MODELS, ANIMAL; FERROCHELATASE; FRIEDREICH ATAXIA; GENE EXPRESSION PROFILING; HEME; HUMANS; IRON; IRON-BINDING PROTEINS; KIDNEY; LIVER; MICE; MICE, KNOCKOUT; MITOCHONDRIA; MYOCARDIUM; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SPLEEN; UROPORPHYRINOGEN III SYNTHETASE;

MAMMALIA;

EID: 70349504414     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0906784106     Document Type: Article

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