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Volumn 95, Issue 1-4, 2011, Pages 1-10

Eicosanoids, β-cell function, and diabetes

Author keywords

Cell destruction; Cell function; 12 HETE; Cyclooxygenase; Cytochrome P450; EETs; Lipoxygenase; PGE2; sEH

Indexed keywords

11,12 EPOXY 5,8,14 ICOSATRIENOIC ACID; 12 HYDROXYICOSATETRAENOIC ACID; 15 HYDROXYICOSATETRAENOIC ACID; 16 HYDROXYICOSATETRAENOIC ACID; 17 HYDROXYICOSATETRAENOIC ACID; 18 HYDROXYICOSATETRAENOIC ACID; 19 HYDROXYICOSATETRAENOIC ACID; 20 HYDROXYICOSATETRAENOIC ACID; 5,6 EPOXY 8,11,14 ICOSATRIENOIC ACID; 8,9 EPOXYICOSATRIENOIC ACID; ACETYLSALICYLIC ACID; CYTOCHROME P450; EPOXYICOSATRIENOIC ACID; ICOSANOID; INDOMETACIN; LEUKOTRIENE A4; LEUKOTRIENE B4; LEUKOTRIENE C4; LEUKOTRIENE D4; LEUKOTRIENE E4; LIPOXYGENASE; NORDIHYDROGUAIARETIC ACID; OMEGA 3 FATTY ACID; PROSTACYCLIN; PROSTAGLANDIN D2; PROSTAGLANDIN E2; PROSTAGLANDIN F2 ALPHA; PROSTAGLANDIN H2; PROSTAGLANDIN SYNTHASE; THROMBOXANE A2; UNCLASSIFIED DRUG;

EID: 79960837542     PISSN: 10988823     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.prostaglandins.2011.06.001     Document Type: Review
Times cited : (91)

References (170)
  • 1
    • 73749083481 scopus 로고    scopus 로고
    • Global estimates of the prevalence of diabetes for 2010 and 2030
    • J.E. Shaw, R.A. Sicree, and P.Z. Zimmet Global estimates of the prevalence of diabetes for 2010 and 2030 Diabetes Res Clin Pract 87 2010 4 14
    • (2010) Diabetes Res Clin Pract , vol.87 , pp. 4-14
    • Shaw, J.E.1    Sicree, R.A.2    Zimmet, P.Z.3
  • 2
    • 28044432292 scopus 로고    scopus 로고
    • Autoimmune destruction of pancreatic beta cells
    • J.W. Yoon, and H.S. Jun Autoimmune destruction of pancreatic beta cells Am J Ther 12 2005 580 591
    • (2005) Am J Ther , vol.12 , pp. 580-591
    • Yoon, J.W.1    Jun, H.S.2
  • 3
    • 33644749322 scopus 로고    scopus 로고
    • Mechanisms of pancreatic beta-cell death in type 1 and type 2 diabetes: Many differences, few similarities
    • M. Cnop, N. Welsh, and J.C. Jonas Mechanisms of pancreatic beta-cell death in type 1 and type 2 diabetes: many differences, few similarities Diabetes 54 2005 S97 S107
    • (2005) Diabetes , vol.54
    • Cnop, M.1    Welsh, N.2    Jonas, J.C.3
  • 4
    • 67649364114 scopus 로고    scopus 로고
    • The role of inflammation in insulitis and beta-cell loss in type 1 diabetes
    • D.L. Eizirik, M.L. Colli, and F. Ortis The role of inflammation in insulitis and beta-cell loss in type 1 diabetes Nat Rev Endocrinol 5 2009 219 226
    • (2009) Nat Rev Endocrinol , vol.5 , pp. 219-226
    • Eizirik, D.L.1    Colli, M.L.2    Ortis, F.3
  • 6
    • 80054870690 scopus 로고    scopus 로고
    • Obesity-associated insulin resistance in skeletal muscle: Role of lipid accumulation and physical inactivity
    • [Epub ahead of print]
    • K. Eckardt, A. Taube, and J. Eckel Obesity-associated insulin resistance in skeletal muscle: Role of lipid accumulation and physical inactivity Rev Endocr Metab Disord 2011 [Epub ahead of print]
    • (2011) Rev Endocr Metab Disord
    • Eckardt, K.1    Taube, A.2    Eckel, J.3
  • 7
    • 78349297565 scopus 로고    scopus 로고
    • Oxidative stress and diabetic complications
    • F. Giacco, and M. Brownlee Oxidative stress and diabetic complications Circ Res 107 2010 1058 1070
    • (2010) Circ Res , vol.107 , pp. 1058-1070
    • Giacco, F.1    Brownlee, M.2
  • 8
    • 78649442666 scopus 로고    scopus 로고
    • Diabetes and inflammation: Fundamental aspects and clinical implications
    • C. Garcia, B. Feve, and P. Ferre Diabetes and inflammation: fundamental aspects and clinical implications Diabetes Metab 36 2010 327 338
    • (2010) Diabetes Metab , vol.36 , pp. 327-338
    • Garcia, C.1    Feve, B.2    Ferre, P.3
  • 9
    • 64149126546 scopus 로고    scopus 로고
    • Regulation of insulin secretion: A matter of phase control and amplitude modulation
    • J.C. Henquin Regulation of insulin secretion: a matter of phase control and amplitude modulation Diabetologia 52 2009 739 751
    • (2009) Diabetologia , vol.52 , pp. 739-751
    • Henquin, J.C.1
  • 10
    • 9444259786 scopus 로고    scopus 로고
    • Pathways in beta-cell stimulus-secretion coupling as targets for therapeutic insulin secretagogues
    • J.C. Henquin Pathways in beta-cell stimulus-secretion coupling as targets for therapeutic insulin secretagogues Diabetes 53 2004 S48 S58
    • (2004) Diabetes , vol.53
    • Henquin, J.C.1
  • 11
    • 0034534288 scopus 로고    scopus 로고
    • Eicosanoid regulation of the renal vasculature
    • J.D. Imig Eicosanoid regulation of the renal vasculature Am J Physiol 279 2000 F965 F981
    • (2000) Am J Physiol , vol.279
    • Imig, J.D.1
  • 12
    • 0036080081 scopus 로고    scopus 로고
    • P-450 metabolites of arachidonic acid in the control of cardiovascular function
    • R.J. Roman P450 metabolites of arachidonic acid in the control of cardiovascular function Physiol Rev 82 2002 131 185 (Pubitemid 34654217)
    • (2002) Physiological Reviews , vol.82 , Issue.1 , pp. 131-185
    • Roman, R.J.1
  • 13
    • 70349636047 scopus 로고    scopus 로고
    • Soluble epoxide hydrolase as a therapeutic target for cardiovascular diseases
    • J.D. Imig, and B.D. Hammock Soluble epoxide hydrolase as a therapeutic target for cardiovascular diseases Nat Rev Drug Discov 8 2009 794 805
    • (2009) Nat Rev Drug Discov , vol.8 , pp. 794-805
    • Imig, J.D.1    Hammock, B.D.2
  • 14
    • 34249110684 scopus 로고    scopus 로고
    • Roles of Lipid Mediators in Kidney Injury
    • DOI 10.1016/j.semnephrol.2007.02.008, PII S0270929507000393, Mechanisms of Tissue Injury in Acute and Chronic Renal Disease
    • C.M. Hao, and M.D. Breyer Roles of lipid mediators in kidney injury Semin Nephrol 27 2007 338 351 (Pubitemid 46802920)
    • (2007) Seminars in Nephrology , vol.27 , Issue.3 , pp. 338-351
    • Hao, C.-M.1    Breyer, M.D.2
  • 15
    • 78650698895 scopus 로고    scopus 로고
    • Functional and pathological roles of the 12- and 15-lipoxygenases
    • A.D. Dobrian, D.C. Lieb, and B.K. Cole Functional and pathological roles of the 12- and 15-lipoxygenases Prog Lipid Res 50 2011 115 131
    • (2011) Prog Lipid Res , vol.50 , pp. 115-131
    • Dobrian, A.D.1    Lieb, D.C.2    Cole, B.K.3
  • 16
    • 33745797993 scopus 로고    scopus 로고
    • Eicosanoids and renal vascular function in diseases
    • DOI 10.1042/CS20050251
    • J.D. Imig Eicosanoids and renal vascular function in diseases Clin Sci 111 2006 21 34 (Pubitemid 44023408)
    • (2006) Clinical Science , vol.111 , Issue.1 , pp. 21-34
    • Imig, J.D.1
  • 17
    • 37349130584 scopus 로고    scopus 로고
    • An update on cyclooxygenase-2 expression and metabolites in the kidney
    • DOI 10.1097/MNH.0b013e3282f1bb7d, PII 0004155220080100000011
    • R.C. Harris An update on cyclooxygenase-2 expression and metabolites in the kidney Curr Opin Nephrol Hypertens 17 2008 64 69 (Pubitemid 350295199)
    • (2008) Current Opinion in Nephrology and Hypertension , vol.17 , Issue.1 , pp. 64-69
    • Harris, R.C.1
  • 19
    • 77956358848 scopus 로고    scopus 로고
    • COX-mediated endothelium-dependent contractions: From the past to recent discoveries
    • M.S. Wong, and P.M. Vanhoutte COX-mediated endothelium-dependent contractions: from the past to recent discoveries Acta Pharmacol Sin 31 2010 1095 1102
    • (2010) Acta Pharmacol Sin , vol.31 , pp. 1095-1102
    • Wong, M.S.1    Vanhoutte, P.M.2
  • 22
    • 1442313873 scopus 로고    scopus 로고
    • Cyclooxygenases, the Kidney, and Hypertension
    • DOI 10.1161/01.HYP.0000116221.27079.ea
    • H.F. Cheng, and R.C. Harris Cyclooxygenases, the kidney, and hypertension Hypertension 43 2004 525 530 (Pubitemid 38282421)
    • (2004) Hypertension , vol.43 , Issue.3 , pp. 525-530
    • Cheng, H.-F.1    Harris, R.C.2
  • 23
    • 3543047940 scopus 로고    scopus 로고
    • Dominance of cyclooxygenase-2 in the regulation of pancreatic islet prostaglandin synthesis
    • R.P. Robertson Dominance of cyclooxygenase-2 in the regulation of pancreatic islet prostaglandin synthesis Diabetes 47 1998 1379 1383
    • (1998) Diabetes , vol.47 , pp. 1379-1383
    • Robertson, R.P.1
  • 24
    • 67651166598 scopus 로고    scopus 로고
    • COX-1 and vascular disease
    • P.M. Vanhoutte COX-1 and vascular disease Clin Pharmacol Ther 86 2009 212 215
    • (2009) Clin Pharmacol Ther , vol.86 , pp. 212-215
    • Vanhoutte, P.M.1
  • 25
    • 65449160912 scopus 로고    scopus 로고
    • Endothelial dysfunction and vascular disease
    • P.M. Vanhoutte, H. Shimokawa, and E.H. Tang Endothelial dysfunction and vascular disease Acta Physiol 196 2009 193 222
    • (2009) Acta Physiol , vol.196 , pp. 193-222
    • Vanhoutte, P.M.1    Shimokawa, H.2    Tang, E.H.3
  • 26
    • 77951755914 scopus 로고    scopus 로고
    • Prostacyclin in vascular diseases - Recent insights and future perspectives
    • J. Kawabe, F. Ushikubi, and N. Hasebe Prostacyclin in vascular diseases - recent insights and future perspectives Circ J 74 2010 836 843
    • (2010) Circ J , vol.74 , pp. 836-843
    • Kawabe, J.1    Ushikubi, F.2    Hasebe, N.3
  • 28
    • 41149086321 scopus 로고    scopus 로고
    • 15-Lipoxygenase-1 in the vasculature: Expanding roles in angiogenesis
    • DOI 10.1161/CIRCRESAHA.107.170191, PII 0000301220080201000003
    • N. Mochizuki, and Y.G. Kwon 15-lipoxygenase-1 in the vasculature: expanding roles in angiogenesis Circ Res 102 2008 143 145 (Pubitemid 351651114)
    • (2008) Circulation Research , vol.102 , Issue.2 , pp. 143-145
    • Mochizuki, N.1    Kwon, Y.-G.2
  • 29
    • 77949363808 scopus 로고    scopus 로고
    • The 5-lipoxygenase/leukotriene pathway in preclinical models of cardiovascular disease
    • D. Poeckel, and C.D. Funk The 5-lipoxygenase/leukotriene pathway in preclinical models of cardiovascular disease Cardiovasc Res 86 2010 243 253
    • (2010) Cardiovasc Res , vol.86 , pp. 243-253
    • Poeckel, D.1    Funk, C.D.2
  • 30
    • 37349120736 scopus 로고    scopus 로고
    • Arachidonic acid metabolites in the cardiovascular system: The role of lipoxygenase isoforms in atherogenesis with particular emphasis on vascular remodeling
    • DOI 10.1097/FJC.0b013e318159f177, PII 0000534420071200000002
    • H. Kuhn, P. Chaitidis, and J. Roffeis Arachidonic Acid metabolites in the cardiovascular system: the role of lipoxygenase isoforms in atherogenesis with particular emphasis on vascular remodeling J Cardiovasc Pharmacol 50 2007 609 620 (Pubitemid 350307029)
    • (2007) Journal of Cardiovascular Pharmacology , vol.50 , Issue.6 , pp. 609-620
    • Kuhn, H.1    Chaitidis, P.2    Roffeis, J.3    Walther, M.4
  • 31
    • 34249287061 scopus 로고    scopus 로고
    • Physiologic and pathophysiologic roles of lipid mediators in the kidney
    • DOI 10.1038/sj.ki.5002192, PII 5002192
    • C.M. Hao, and M.D. Breyer Physiologic and pathophysiologic roles of lipid mediators in the kidney Kidney Int 71 2007 1105 1115 (Pubitemid 46809137)
    • (2007) Kidney International , vol.71 , Issue.11 , pp. 1105-1115
    • Hao, C.-M.1    Breyer, M.D.2
  • 32
    • 33748114969 scopus 로고    scopus 로고
    • Renal cytochrome P450-derived eicosanoids and hypertension
    • M.H. Wang Renal cytochrome P450-derived eicosanoids and hypertension Curr Hypertens Rev 2 2006 227 236
    • (2006) Curr Hypertens Rev , vol.2 , pp. 227-236
    • Wang, M.H.1
  • 33
    • 23944460748 scopus 로고    scopus 로고
    • Epoxide hydrolase and epoxygenase metabolites as therapeutic targets for renal diseases
    • J.D. Imig Epoxide hydrolase and epoxygenase metabolites as therapeutic targets for renal diseases Am J Physiol 289 2005 F496 F503
    • (2005) Am J Physiol , vol.289
    • Imig, J.D.1
  • 35
    • 0030051805 scopus 로고    scopus 로고
    • Identification of epoxyeicosatrienoic acids as endothelium-derived hyperpolarizing factors
    • W.B. Campbell, D. Gebremedhin, and P.F. Pratt Identification of epoxyeicosatrienoic acids as endothelium-derived hyperpolarizing factors Circ Res 78 1996 415 423 (Pubitemid 26072547)
    • (1996) Circulation Research , vol.78 , Issue.3 , pp. 415-423
    • Campbell, W.B.1    Gebremedhin, D.2    Pratt, P.F.3    Harder, D.R.4
  • 36
    • 73349133346 scopus 로고    scopus 로고
    • 20-125-Iodo-14,15-epoxyeicosa-5(Z)-enoic acid: A high-affinity radioligand used to characterize the epoxyeicosatrienoic acid antagonist binding site
    • Y. Chen, J.R. Falck, and V.R. Tuniki 20-125-Iodo-14,15-epoxyeicosa-5(Z)- enoic acid: a high-affinity radioligand used to characterize the epoxyeicosatrienoic acid antagonist binding site J Pharmacol Exp Ther 331 2008 1137 1145
    • (2008) J Pharmacol Exp Ther , vol.331 , pp. 1137-1145
    • Chen, Y.1    Falck, J.R.2    Tuniki, V.R.3
  • 37
    • 78650777434 scopus 로고    scopus 로고
    • 14,15-Dihydroxy-eicosa-5(Z)-enoic acid selectively inhibits 14,15-epoxyeicosatrienoic acid-induced relaxations in bovine coronary arteries
    • I.A. Bukhari, K.M. Gauthier, and S.G. Jagadeesh 14,15-Dihydroxy-eicosa- 5(Z)-enoic acid selectively inhibits 14,15-epoxyeicosatrienoic acid-induced relaxations in bovine coronary arteries J Pharmacol Exp Ther 336 2011 47 55
    • (2011) J Pharmacol Exp Ther , vol.336 , pp. 47-55
    • Bukhari, I.A.1    Gauthier, K.M.2    Jagadeesh, S.G.3
  • 41
    • 0024289847 scopus 로고
    • 19(S)-hydroxyeicosatetraenoic acid is a potent stimulator of renal Na, K-ATPase
    • B. Escalante, J.R. Falck, and P. Yadagiri 19(S)-hydroxyeicosatetraenoic acid is a potent stimulator of renal Na, K-ATPase Biochem Biophys Res Commun 152 1988 1259 1274
    • (1988) Biochem Biophys Res Commun , vol.152 , pp. 1259-1274
    • Escalante, B.1    Falck, J.R.2    Yadagiri, P.3
  • 42
    • 0028271810 scopus 로고
    • Cytochrome P450 arachidonate metabolites affect ion fluxes in rabbit medullary thick ascending limb
    • B. Escalante, D. Erlij, and J.R. Falck Cytochrome P450 arachidonate metabolites affect ion fluxes in rabbit medullary thick ascending limb Am J Physiol 266 1994 C1775 C1782
    • (1994) Am J Physiol , vol.266
    • Escalante, B.1    Erlij, D.2    Falck, J.R.3
  • 44
    • 77958461840 scopus 로고    scopus 로고
    • 20-hydroxyeicosatetraeonic acid: A new target for the treatment of hypertension
    • J.M. Williams, S. Murphy, and M. Burke 20-hydroxyeicosatetraeonic acid: a new target for the treatment of hypertension J Cardiovasc Pharmacol 56 2010 336 344
    • (2010) J Cardiovasc Pharmacol , vol.56 , pp. 336-344
    • Williams, J.M.1    Murphy, S.2    Burke, M.3
  • 45
    • 0030030057 scopus 로고    scopus 로고
    • Cytokines and nitric oxide in islet inflammation and diabetes
    • M.L. McDaniel, G. Kwon, and J.R. Hill Cytokines and nitric oxide in islet inflammation and diabetes Proc Soc Exp Biol Med 211 1996 24 32
    • (1996) Proc Soc Exp Biol Med , vol.211 , pp. 24-32
    • McDaniel, M.L.1    Kwon, G.2    Hill, J.R.3
  • 46
    • 0033760442 scopus 로고    scopus 로고
    • Triggering and amplifying pathways of regulation of insulin secretion by glucose
    • J.C. Henquin Triggering and amplifying pathways of regulation of insulin secretion by glucose Diabetes 49 2000 1751 1760
    • (2000) Diabetes , vol.49 , pp. 1751-1760
    • Henquin, J.C.1
  • 49
    • 0020570204 scopus 로고
    • Lipoxygenase pathway in islet endocrine cells. Oxidative metabolism of arachidonic acid promotes insulin release
    • S. Metz, M. VanRollins, and R. Strife Lipoxygenase pathway in islet endocrine cells: Oxidative metabolism of arachidonic acid promotes insulin release J Clin Invest 71 1983 1191 1205 (Pubitemid 13098905)
    • (1983) Journal of Clinical Investigation , vol.71 , Issue.5 , pp. 1191-1205
    • Metz, S.1    VanRollins, M.2    Strife, R.3
  • 50
    • 0022480919 scopus 로고
    • Arachidonic acid metabolite regulation of insulin secretion
    • R.P. Robertson Arachidonic acid metabolite regulation of insulin secretion Diabetes Metab Rev 2 1986 261 296 (Pubitemid 16009510)
    • (1986) Diabetes/Metabolism Reviews , vol.2 , Issue.3-4 , pp. 261-296
    • Robertson, R.P.1
  • 51
    • 0036014899 scopus 로고    scopus 로고
    • Inhibition of interleukin-1β-induced COX-2 and EP3 gene expression by sodium salicylate enhances pancreatic islet β-cell function
    • 3 gene expression by sodium salicylate enhances pancreatic islet beta-cell function Diabetes 51 2002 1772 1778 (Pubitemid 34564289)
    • (2002) Diabetes , vol.51 , Issue.6 , pp. 1772-1778
    • Tran, P.O.T.1    Gleason, C.E.2    Paul Robertson, R.3
  • 52
    • 33847034426 scopus 로고    scopus 로고
    • The role of arachidonic acid and its metabolites in insulin secretion from human islets of Langerhans
    • S.J. Persaud, D. Muller, and V.D. Belin The role of arachidonic acid and its metabolites in insulin secretion from human islets of Langerhans Diabetes 56 2007 197 203
    • (2007) Diabetes , vol.56 , pp. 197-203
    • Persaud, S.J.1    Muller, D.2    Belin, V.D.3
  • 54
    • 0033615530 scopus 로고    scopus 로고
    • Prostaglandin E(2) mediates inhibition of insulin secretion by interleukin-1beta
    • P.O. Tran, C.E. Gleason, and V. Poitout Prostaglandin E(2) mediates inhibition of insulin secretion by interleukin-1beta J Biol Chem 274 1999 31245 31248
    • (1999) J Biol Chem , vol.274 , pp. 31245-31248
    • Tran, P.O.1    Gleason, C.E.2    Poitout, V.3
  • 57
    • 0025259294 scopus 로고
    • Lipoxygenase-generated icosanoids inhibit glucose-induced insulin release from rat islets
    • DOI 10.1016/0952-3278(90)90111-W
    • M.H. Nathan, and S.B. Pek Lipoxygenase-generated eicosanoids inhibit glucose-induced insulin release from rat islets Prostaglandins Leukot Essent Fatty Acids 40 1990 21 25 (Pubitemid 20145306)
    • (1990) Prostaglandins Leukotrienes and Essential Fatty Acids , vol.40 , Issue.1 , pp. 21-25
    • Nathan, M.H.1    Pek, S.B.2
  • 58
    • 0021352660 scopus 로고
    • Effects on glucose-induced insulin secretion of lipoxygenase-derived metabolites of arachidonic acid
    • S.A. Metz, R.C. Murphy, and W. Fujimoto Effects on glucose-induced insulin secretion of lipoxygenase-derived metabolites of arachidonic acid Diabetes 33 1984 119 124 (Pubitemid 14184696)
    • (1984) Diabetes , vol.33 , Issue.2 , pp. 119-124
    • Metz, S.A.1    Murphy, R.C.2    Fujimoto, W.3
  • 59
    • 43049088783 scopus 로고    scopus 로고
    • Identification of ALOX5 as a gene regulating adiposity and pancreatic function
    • M. Mehrabian, F.T. Schulthess, and M. Nebohacova Identification of ALOX5 as a gene regulating adiposity and pancreatic function Diabetologia 51 2008 978 988
    • (2008) Diabetologia , vol.51 , pp. 978-988
    • Mehrabian, M.1    Schulthess, F.T.2    Nebohacova, M.3
  • 60
    • 0031598596 scopus 로고    scopus 로고
    • The role of 12-lipoxygenase in pancreatic beta-cells
    • D. Bleich, S. Chen, and J.L. Gu The role of 12-lipoxygenase in pancreatic beta-cells Int J Mol Med 1 1998 265 272
    • (1998) Int J Mol Med , vol.1 , pp. 265-272
    • Bleich, D.1    Chen, S.2    Gu, J.L.3
  • 61
    • 0034267943 scopus 로고    scopus 로고
    • Augmented insulinotropic action of arachidonic acid through the lipoxygenase pathway in the obese Zucker rat
    • B. Ahren, L.J. Magrum, and P.J. Havel Augmented insulinotropic action of arachidonic acid through the lipoxygenase pathway in the obese Zucker rat Obes Res 8 2000 475 480
    • (2000) Obes Res , vol.8 , pp. 475-480
    • Ahren, B.1    Magrum, L.J.2    Havel, P.J.3
  • 63
    • 76149125754 scopus 로고    scopus 로고
    • 12-Lipoxygenase products reduce insulin secretion and {beta}-cell viability in human islets
    • K. Ma, C.S. Nunemaker, and R. Wu 12-Lipoxygenase products reduce insulin secretion and {beta}-cell viability in human islets J Clin Endocrinol Metab 95 2010 887 893
    • (2010) J Clin Endocrinol Metab , vol.95 , pp. 887-893
    • Ma, K.1    Nunemaker, C.S.2    Wu, R.3
  • 64
    • 0020956157 scopus 로고
    • Epoxyeicosatrienoic acids stimulate glucagon and insulin release from isolated rat pancreatic islets
    • J.R. Falck, S. Manna, and J. Moltz Epoxyeicosatrienoic acids stimulate glucagon and insulin release from isolated rat pancreatic islets Biochem Biophys Res Commun 114 1983 743 749 (Pubitemid 13030721)
    • (1983) Biochemical and Biophysical Research Communications , vol.114 , Issue.2 , pp. 743-749
    • Falck, J.R.1    Manna, S.2    Moltz, J.3
  • 65
    • 0031057495 scopus 로고    scopus 로고
    • Predominant expression of an arachidonate epoxygenase in islets of langerhans cells in human and rat pancreas
    • DOI 10.1210/en.138.3.1338
    • D.C. Zeldin, J. Foley, and J.E. Boyle Predominant expression of an arachidonate epoxygenase in islets of Langerhans cells in human and rat pancreas Endocrinology 138 1997 1338 1346 (Pubitemid 27089795)
    • (1997) Endocrinology , vol.138 , Issue.3 , pp. 1338-1346
    • Zeldin, D.C.1    Foley, J.2    Boyle, J.E.3    Moomaw, C.R.4    Tomer, K.B.5    Parker, C.6    Steenbergen, C.7    Wu, S.8
  • 66
    • 77957831701 scopus 로고    scopus 로고
    • Endothelial expression of human cytochrome P450 epoxygenases lowers blood pressure and attenuates hypertension-induced renal injury in mice
    • C.R. Lee, J.D. Imig, and M.L. Edin Endothelial expression of human cytochrome P450 epoxygenases lowers blood pressure and attenuates hypertension-induced renal injury in mice FASEB J 24 2010 3770 3781
    • (2010) FASEB J , vol.24 , pp. 3770-3781
    • Lee, C.R.1    Imig, J.D.2    Edin, M.L.3
  • 67
    • 70350593993 scopus 로고    scopus 로고
    • Insulin resistance and endothelial dysfunction: Are epoxyeicosatrienoic acids the link?
    • S. Mustafa, V. Sharma, and J.H. McNeill Insulin resistance and endothelial dysfunction: Are epoxyeicosatrienoic acids the link? Exp Clin Cardiol 14 2009 e41 e50
    • (2009) Exp Clin Cardiol , vol.14
    • Mustafa, S.1    Sharma, V.2    McNeill, J.H.3
  • 68
    • 77954902049 scopus 로고    scopus 로고
    • Inhibition or deletion of soluble epoxide hydrolase prevents hyperglycemia, promotes insulin secretion, and reduces islet apoptosis
    • P. Luo, H.H. Chang, and Y. Zhou Inhibition or deletion of soluble epoxide hydrolase prevents hyperglycemia, promotes insulin secretion, and reduces islet apoptosis J Pharmacol Exp Ther 334 2010 430 438
    • (2010) J Pharmacol Exp Ther , vol.334 , pp. 430-438
    • Luo, P.1    Chang, H.H.2    Zhou, Y.3
  • 69
    • 18244364592 scopus 로고    scopus 로고
    • Inflammation-mediated dysfunction and apoptosis in pancreatic islet transplantation: Implications for intrahepatic grafts
    • DOI 10.1189/jlb.1104649
    • N.R. Barshes, S. Wyllie, and J.A. Goss Inflammation-mediated dysfunction and apoptosis in pancreatic islet transplantation: implications for intrahepatic grafts J Leukoc Biol 77 2005 587 597 (Pubitemid 40628740)
    • (2005) Journal of Leukocyte Biology , vol.77 , Issue.5 , pp. 587-597
    • Barshes, N.R.1    Wyllie, S.2    Goss, J.A.3
  • 70
    • 0842284787 scopus 로고    scopus 로고
    • Glucose-induced regulation of COX-2 expression in human islets of Langerhans
    • S.J. Persaud, C.J. Burns, and V.D. Belin Glucose-induced regulation of COX-2 expression in human islets of Langerhans Diabetes 53 2004 S190 S192
    • (2004) Diabetes , vol.53
    • Persaud, S.J.1    Burns, C.J.2    Belin, V.D.3
  • 71
    • 31444445097 scopus 로고    scopus 로고
    • Increased expression of cyclooxygenase-2 in human pancreatic islets treated with high glucose or ligands of the advanced glycation endproduct-specific receptor (AGER), and in islets from diabetic mice
    • DOI 10.1007/s00125-005-0065-7
    • N. Shanmugam, I.T. Todorov, and I. Nair Increased expression of cyclooxygenase-2 in human pancreatic islets treated with high glucose or ligands of the advanced glycation endproduct-specific receptor (AGER), and in islets from diabetic mice Diabetologia 4 2006 100 107 (Pubitemid 43151620)
    • (2006) Diabetologia , vol.49 , Issue.1 , pp. 100-107
    • Shanmugam, N.1    Todorov, I.T.2    Nair, I.3    Omori, K.4    Reddy, M.A.5    Natarajan, R.6
  • 72
    • 0027162479 scopus 로고
    • Structural determination and promoter analysis of the chicken mitogen-inducible prostaglandin G/H synthase gene and genetic mapping of the murine homolog
    • DOI 10.1006/abbi.1993.1034
    • W. Xie, J.R. Merrill, and W.S. Bradshaw Structural determination and promoter analysis of the chicken mitogen-inducible prostaglandin G/H synthase gene and genetic mapping of the murine homolog Arch Biochem Biophys 300 1993 247 252 (Pubitemid 23225743)
    • (1993) Archives of Biochemistry and Biophysics , vol.300 , Issue.1 , pp. 247-252
    • Xie, W.1    Merrill, J.R.2    Bradshaw, W.S.3    Simmons, D.L.4
  • 74
    • 0025095283 scopus 로고
    • Cytotoxic effects of cytokines on islet β-cells: Evidence for involvement of eicosanoids
    • A. Rabinovitch, H. Baquerizo, and W. Sumoski Cytotoxic effects of cytokines on islet beta-cells: evidence for involvement of eicosanoids Endocrinology 126 1990 67 71 (Pubitemid 20037126)
    • (1990) Endocrinology , vol.126 , Issue.1 , pp. 67-71
    • Rabinovitch, A.1    Baquerizo, H.2    Sumoski, W.3
  • 76
    • 78650426510 scopus 로고    scopus 로고
    • Effects of cyclooxygenase-2 inhibitor and adenosine triphosphate- sensitive potassium channel opener in syngeneic mouse islet transplantation
    • J.H. Juang, and C.H. Kuo Effects of cyclooxygenase-2 inhibitor and adenosine triphosphate-sensitive potassium channel opener in syngeneic mouse islet transplantation Transplant Proc 42 2010 4221 4224
    • (2010) Transplant Proc , vol.42 , pp. 4221-4224
    • Juang, J.H.1    Kuo, C.H.2
  • 77
    • 0041376742 scopus 로고    scopus 로고
    • Prevention of primary non-function of islet xenografts in autoimmune diabetic NOD mice by anti-inflammatory agents
    • DOI 10.1007/s00125-003-1154-0
    • C. Gysemans, K. Stoffels, and A. Giulietti Prevention of primary non-function of islet xenografts in autoimmune diabetic NOD mice by anti-inflammatory agents Diabetologia 46 2003 1115 1123 (Pubitemid 37041242)
    • (2003) Diabetologia , vol.46 , Issue.8 , pp. 1115-1123
    • Gysemans, C.1    Stoffels, K.2    Giulietti, A.3    Overbergh, L.4    Waer, M.5    Lannoo, M.6    Feige, U.7    Mathieu, C.8
  • 78
    • 16844383761 scopus 로고    scopus 로고
    • Activation of 12-lipoxygenase in proinflammatory cytokine-mediated beta cell toxicity
    • DOI 10.1007/s00125-005-1673-y
    • M. Chen, Z.D. Yang, and K.M. Smith Activation of 12-lipoxygenase in proinflammatory cytokine-mediated beta cell toxicity Diabetologia 48 2005 486 495 (Pubitemid 40487296)
    • (2005) Diabetologia , vol.48 , Issue.3 , pp. 486-495
    • Chen, M.1    Yang, Z.D.2    Smith, K.M.3    Carter, J.D.4    Nadler, J.L.5
  • 80
    • 33845382310 scopus 로고    scopus 로고
    • Enhancing engraftment of neonatal porcine xenoislet with CTLA4Ig and nordihydroguaiaretic acid
    • S.H. Fu, Y.T. Chen, and C.H. Chiang Enhancing engraftment of neonatal porcine xenoislet with CTLA4Ig and nordihydroguaiaretic acid Transplant Proc 38 2006 3283 3285
    • (2006) Transplant Proc , vol.38 , pp. 3283-3285
    • Fu, S.H.1    Chen, Y.T.2    Chiang, C.H.3
  • 81
    • 34547135686 scopus 로고    scopus 로고
    • Cytochrome P450 epoxygenases protect endothelial cells from apoptosis induced by tumor necrosis factor-alpha via MAPK and PI3K/Akt signaling pathways
    • S. Yang, L. Lin, and J.X. Chen Cytochrome P450 epoxygenases protect endothelial cells from apoptosis induced by tumor necrosis factor-alpha via MAPK and PI3K/Akt signaling pathways Am J Physiol 293 2007 H142 H151
    • (2007) Am J Physiol , vol.293
    • Yang, S.1    Lin, L.2    Chen, J.X.3
  • 82
    • 67049119782 scopus 로고    scopus 로고
    • Soluble epoxide inhibition is protective against cerebral ischemia via vascular and neural protection
    • A.N. Simpkins, R.D. Rudic, and D.A. Schreihofer Soluble epoxide inhibition is protective against cerebral ischemia via vascular and neural protection Am J Pathol 174 2009 2086 2095
    • (2009) Am J Pathol , vol.174 , pp. 2086-2095
    • Simpkins, A.N.1    Rudic, R.D.2    Schreihofer, D.A.3
  • 84
    • 33845881411 scopus 로고    scopus 로고
    • Mechanisms linking obesity to insulin resistance and type 2 diabetes
    • DOI 10.1038/nature05482, PII NATURE05482
    • S.E. Kahn, R.L. Hull, and K.M. Utzschneider Mechanisms linking obesity to insulin resistance and type 2 diabetes Nature 444 2006 840 846 (Pubitemid 46024990)
    • (2006) Nature , vol.444 , Issue.7121 , pp. 840-846
    • Kahn, S.E.1    Hull, R.L.2    Utzschneider, K.M.3
  • 85
    • 78649842241 scopus 로고    scopus 로고
    • Genomics, type 2 diabetes, and obesity
    • M.I. McCarthy Genomics, type 2 diabetes, and obesity N Engl J Med 363 2010 2339 2350
    • (2010) N Engl J Med , vol.363 , pp. 2339-2350
    • McCarthy, M.I.1
  • 86
    • 78751486038 scopus 로고    scopus 로고
    • Insulin resistance, defective insulin-mediated fatty acid suppression, and coronary artery calcification in subjects with and without type 1 diabetes: The CACTI study
    • I.E. Schauer, J.K. Snell-Bergeon, and B.C. Bergman Insulin resistance, defective insulin-mediated fatty acid suppression, and coronary artery calcification in subjects with and without type 1 diabetes: the CACTI study Diabetes 60 2011 306 314
    • (2011) Diabetes , vol.60 , pp. 306-314
    • Schauer, I.E.1    Snell-Bergeon, J.K.2    Bergman, B.C.3
  • 87
    • 0025945012 scopus 로고
    • Insulin resistance - Mechanisms, syndromes, and implications
    • D.E. Moller, and J.S. Flier Insulin resistance - mechanisms, syndromes, and implications N Engl J Med 325 1991 938 948
    • (1991) N Engl J Med , vol.325 , pp. 938-948
    • Moller, D.E.1    Flier, J.S.2
  • 89
    • 33847638020 scopus 로고    scopus 로고
    • Eicosanoids in inflammation: Biosynthesis, pharmacology, and therapeutic frontiers
    • DOI 10.2174/156802607779941314
    • S.P. Khanapure, D.S. Garvey, and D.R. Janero Eicosanoids in inflammation: biosynthesis, pharmacology, and therapeutic frontiers Curr Top Med Chem 7 2007 311 340 (Pubitemid 46358664)
    • (2007) Current Topics in Medicinal Chemistry , vol.7 , Issue.3 , pp. 311-340
    • Khanapure, S.P.1    Garvey, D.S.2    Janero, D.R.3    Letts, L.G.4
  • 90
    • 0023694802 scopus 로고
    • Eicosanoids and inflammation
    • K.I. Williams, and G.A.G.A. Higgs Eicosanoids and inflammation J Pathol 156 1988 101 110
    • (1988) J Pathol , vol.156 , pp. 101-110
    • Williams, K.I.1    Higgs, G.A.G.A.2
  • 93
    • 67650484314 scopus 로고    scopus 로고
    • COX-2-mediated inflammation in fat is crucial for obesity-linked insulin resistance and fatty liver
    • P.S. Hsieh, J.S. Jin, and C.F. Chiang COX-2-mediated inflammation in fat is crucial for obesity-linked insulin resistance and fatty liver Obesity 17 2009 1150 1157
    • (2009) Obesity , vol.17 , pp. 1150-1157
    • Hsieh, P.S.1    Jin, J.S.2    Chiang, C.F.3
  • 94
    • 1442325581 scopus 로고    scopus 로고
    • Molecular Mechanisms of High Glucose-Induced Cyclooxygenase-2 Expression in Monocytes
    • DOI 10.2337/diabetes.53.3.795
    • N. Shanmugam, G. Gaw, and I.R. Natarajan Molecular mechanisms of high glucose-induced cyclooxygenase-2 expression in monocytes Diabetes 53 2004 795 802 (Pubitemid 38270651)
    • (2004) Diabetes , vol.53 , Issue.3 , pp. 795-802
    • Shanmugam, N.1    Gonzalo, I.T.G.2    Natarajan, R.3
  • 96
    • 0021960218 scopus 로고
    • Increased prostaglandin production by glomeruli isolated from rats with streptozotocin-induced diabetes mellitus
    • M. Schambelan, S. Blake, and J. Sraer Increased prostaglandin production by glomeruli isolated from rats with streptozotocin-induced diabetes mellitus J Clin Invest 75 1985 404 412 (Pubitemid 15143479)
    • (1985) Journal of Clinical Investigation , vol.75 , Issue.2 , pp. 404-412
    • Schambelan, M.1    Blake, S.2    Sraer, J.3
  • 97
    • 0042317299 scopus 로고    scopus 로고
    • Regulation of cyclooxygenase-2 expression in monocytes by ligation of the receptor for advanced glycation end products
    • DOI 10.1074/jbc.M302828200
    • N. Shanmugam, Y.S. Kim, and L. Lanting Regulation of cyclooxygenase-2 expression in monocytes by ligation of the receptor for advanced glycation end products J Biol Chem 278 2003 34834 34844 (Pubitemid 37102242)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.37 , pp. 34834-34844
    • Shanmugam, N.1    Kim, Y.S.2    Lanting, L.3    Natarajan, R.4
  • 98
    • 2342423022 scopus 로고    scopus 로고
    • In Vivo Chromatin Remodeling Events Leading to Inflammatory Gene Transcription under Diabetic Conditions
    • DOI 10.1074/jbc.M311786200
    • F. Miao, I.G. Gonzalo, and L. Lanting In vivo chromatin remodeling events leading to inflammatory gene transcription under diabetic conditions J Biol Chem 279 2004 18091 18097 (Pubitemid 38560579)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.17 , pp. 18091-18097
    • Miao, F.1    Gonzalo, I.G.2    Lanting, L.3    Natarajan, R.4
  • 100
    • 75149164466 scopus 로고    scopus 로고
    • Suppressive effect of COX2 inhibitor on the progression of adipose inflammation in high-fat-induced obese rats
    • P.S. Hsieh, K.C. Lu, and C.F. Chiang Suppressive effect of COX2 inhibitor on the progression of adipose inflammation in high-fat-induced obese rats Eur J Clin Invest 40 2010 164 171
    • (2010) Eur J Clin Invest , vol.40 , pp. 164-171
    • Hsieh, P.S.1    Lu, K.C.2    Chiang, C.F.3
  • 102
    • 0028920386 scopus 로고
    • Mediation of hyperglycemia-evoked gastric slow-wave dysrhythmias by endogenous prostaglandins
    • W.L. Hasler, H.C. Soudah, and G. Dulai Mediation of hyperglycemia-evoked gastric slow-wave dysrhythmias by endogenous prostaglandins Gastroenterology 108 1995 727 736
    • (1995) Gastroenterology , vol.108 , pp. 727-736
    • Hasler, W.L.1    Soudah, H.C.2    Dulai, G.3
  • 105
    • 74949127867 scopus 로고    scopus 로고
    • Cyclooxygenase 2 inhibition exacerbates palmitate-induced inflammation and insulin resistance in skeletal muscle cells
    • T. Coll, X. Palomer, and F. Blanco-Vaca Cyclooxygenase 2 inhibition exacerbates palmitate-induced inflammation and insulin resistance in skeletal muscle cells Endocrinology 151 2010 537 548
    • (2010) Endocrinology , vol.151 , pp. 537-548
    • Coll, T.1    Palomer, X.2    Blanco-Vaca, F.3
  • 107
    • 0141955279 scopus 로고    scopus 로고
    • Association of a promoter variant in the inducible cyclooxygenase-2 gene (PTGS2) with type 2 diabetes mellitus in Pima Indians
    • DOI 10.1007/s00439-003-1000-y
    • Y.L. Konheim, and J.K. Wolford Association of a promoter variant in the inducible cyclooxygenase-2 gene (PTGS2) with type 2 diabetes mellitus in Pima Indians Hum Genet 113 2003 377 381 (Pubitemid 37254241)
    • (2003) Human Genetics , vol.113 , Issue.5 , pp. 377-381
    • Konheim, Y.L.1    Wolford, J.K.2
  • 108
    • 62649173099 scopus 로고    scopus 로고
    • Association of polymorphisms in cyclooxygenase (COX)-2 with coronary and carotid calcium in the Diabetes Heart Study
    • M.E. Rudock, Y. Liu, and J.T. Ziegler Association of polymorphisms in cyclooxygenase (COX)-2 with coronary and carotid calcium in the Diabetes Heart Study Atherosclerosis 203 2009 459 465
    • (2009) Atherosclerosis , vol.203 , pp. 459-465
    • Rudock, M.E.1    Liu, Y.2    Ziegler, J.T.3
  • 109
    • 79959209302 scopus 로고    scopus 로고
    • A polymorphism in the cyclooxygenase 2 gene in type 1 diabetic patients with nephropathy
    • J.A. Hubacek, T. Pelikanova, and V. Lanska A polymorphism in the cyclooxygenase 2 gene in type 1 diabetic patients with nephropathy Physiol Res 60 2011 377 380
    • (2011) Physiol Res , vol.60 , pp. 377-380
    • Hubacek, J.A.1    Pelikanova, T.2    Lanska, V.3
  • 110
    • 0033588022 scopus 로고    scopus 로고
    • 1. Lipoxygenases: Occurrence, functions, catalysis, and acquisition of substrate
    • A.R. Brash, and 1. Lipoxygenases: occurrence, functions, catalysis, and acquisition of substrate J Biol Chem 274 1999 23679 23682
    • (1999) J Biol Chem , vol.274 , pp. 23679-23682
    • Brash, A.R.1
  • 111
    • 4444350561 scopus 로고    scopus 로고
    • Lipid inflammatory mediators in diabetic vascular disease
    • DOI 10.1161/01.ATV.0000133606.69732.4c
    • R. Natarajan, and J.L. Nadler Lipid inflammatory mediators in diabetic vascular disease Arterioscler Thromb Vasc Biol 24 2004 1542 1548 (Pubitemid 39180875)
    • (2004) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.24 , Issue.9 , pp. 1542-1548
    • Natarajan, R.1    Nadler, J.L.2
  • 112
    • 70349639659 scopus 로고    scopus 로고
    • 12/15-Lipoxygenase is required for the early onset of high fat diet-induced adipose tissue inflammation and insulin resistance in mice
    • D.D. Sears, P.D. Miles, and J. Chapman 12/15-Lipoxygenase is required for the early onset of high fat diet-induced adipose tissue inflammation and insulin resistance in mice PLoS One 4 2009 e7250
    • (2009) PLoS One , vol.4 , pp. 7250
    • Sears, D.D.1    Miles, P.D.2    Chapman, J.3
  • 113
    • 57049099790 scopus 로고    scopus 로고
    • 12-Lipoxygenase-knockout mice are resistant to inflammatory effects of obesity induced by Western diet
    • C.S. Nunemaker, M. Chen, and H. Pei 12-Lipoxygenase-knockout mice are resistant to inflammatory effects of obesity induced by Western diet Am J Physiol 295 2008 E1065 E1075
    • (2008) Am J Physiol , vol.295
    • Nunemaker, C.S.1    Chen, M.2    Pei, H.3
  • 114
    • 77951193688 scopus 로고    scopus 로고
    • Lipocalin-2 deficiency attenuates insulin resistance associated with aging and obesity
    • I.K. Law, A. Xu, and K.S. Lam Lipocalin-2 deficiency attenuates insulin resistance associated with aging and obesity Diabetes 59 2010 872 882
    • (2010) Diabetes , vol.59 , pp. 872-882
    • Law, I.K.1    Xu, A.2    Lam, K.S.3
  • 118
    • 78650788269 scopus 로고    scopus 로고
    • Evidence for activation of inflammatory lipoxygenase pathways in visceral adipose tissue of obese Zucker rats
    • S.K. Chakrabarti, Y. Wen, and A.D. Dobrian Evidence for activation of inflammatory lipoxygenase pathways in visceral adipose tissue of obese Zucker rats Am J Physiol 300 2011 E175 E187
    • (2011) Am J Physiol , vol.300
    • Chakrabarti, S.K.1    Wen, Y.2    Dobrian, A.D.3
  • 119
    • 77951630780 scopus 로고    scopus 로고
    • 5-lipoxygenase activating protein signals adipose tissue inflammation and lipid dysfunction in experimental obesity
    • R. Horrillo, A. Gonzalez-Periz, and M. Martinez-Clemente 5-lipoxygenase activating protein signals adipose tissue inflammation and lipid dysfunction in experimental obesity J Immunol 184 2010 3978 3987
    • (2010) J Immunol , vol.184 , pp. 3978-3987
    • Horrillo, R.1    Gonzalez-Periz, A.2    Martinez-Clemente, M.3
  • 120
    • 0037477790 scopus 로고    scopus 로고
    • Increased production of 12/15 lipoxygenase eicosanoids accelerates monocyte/endothelial interactions in diabetic db/db mice
    • DOI 10.1074/jbc.M301175200
    • M.E. Hatley, S. Srinivasan, and K.B. Reilly Increased production of 12/15 lipoxygenase eicosanoids accelerates monocyte/endothelial interactions in diabetic db/db mice J Biol Chem 278 2003 25369 25375 (Pubitemid 36835286)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.28 , pp. 25369-25375
    • Hatley, M.E.1    Srinivasan, S.2    Reilly, K.B.3    Bolick, D.T.4    Hedrick, C.C.5
  • 121
    • 77954264059 scopus 로고    scopus 로고
    • Profile of lipid and protein autacoids in diabetic vitreous correlates with the progression of diabetic retinopathy
    • M.L. Schwartzman, P. Iserovich, and K. Gotlinger Profile of lipid and protein autacoids in diabetic vitreous correlates with the progression of diabetic retinopathy Diabetes 59 2010 1780 1788
    • (2010) Diabetes , vol.59 , pp. 1780-1788
    • Schwartzman, M.L.1    Iserovich, P.2    Gotlinger, K.3
  • 122
    • 33847025363 scopus 로고    scopus 로고
    • The role of 12/15-lipoxygenase in the expression of interleukin-6 and tumor necrosis factor-alpha in macrophages
    • Y. Wen, J. Gu, and S.K. Chakrabarti The role of 12/15-lipoxygenase in the expression of interleukin-6 and tumor necrosis factor-alpha in macrophages Endocrinology 148 2007 1313 1322
    • (2007) Endocrinology , vol.148 , pp. 1313-1322
    • Wen, Y.1    Gu, J.2    Chakrabarti, S.K.3
  • 123
    • 41749097860 scopus 로고    scopus 로고
    • Role of 12/15-lipoxygenase in the expression of MCP-1 in mouse macrophages
    • Y. Wen, J. Gu, and G.E. Vandenhoff Role of 12/15-lipoxygenase in the expression of MCP-1 in mouse macrophages Am J Physiol 294 2008 H1933 H1938
    • (2008) Am J Physiol , vol.294
    • Wen, Y.1    Gu, J.2    Vandenhoff, G.E.3
  • 124
    • 69749102190 scopus 로고    scopus 로고
    • 12/15-Lipoxygenase products induce inflammation and impair insulin signaling in 3T3-L1 adipocytes
    • S.K. Chakrabarti, B.K. Cole, and Y. Wen 12/15-Lipoxygenase products induce inflammation and impair insulin signaling in 3T3-L1 adipocytes Obesity 17 2009 1657 1663
    • (2009) Obesity , vol.17 , pp. 1657-1663
    • Chakrabarti, S.K.1    Cole, B.K.2    Wen, Y.3
  • 125
    • 0033816461 scopus 로고    scopus 로고
    • Masoprocol decreases serum triglyceride concentrations in rats with fructose-induced hypertriglyceridemia
    • K.A. Scribner, T.M. Gadbois, and M. Gowri Masoprocol decreases serum triglyceride concentrations in rats with fructose-induced hypertriglyceridemia Metabolism 49 2000 1106 1110
    • (2000) Metabolism , vol.49 , pp. 1106-1110
    • Scribner, K.A.1    Gadbois, T.M.2    Gowri, M.3
  • 127
    • 0036499692 scopus 로고    scopus 로고
    • A natural protective mechanism against hyperglycaemia in vascular endothelial and smooth-muscle cells: Role of glucose and 12- hydroxyeicosatetraenoic acid
    • DOI 10.1042/0264-6021:3620413
    • E. Alpert, A. Gruzman, and H. Totary A natural protective mechanism against hyperglycaemia in vascular endothelial and smooth-muscle cells: Role of glucose and 12-hydroxyeicosatetraenoic acid Biochem J 362 2002 413 422 (Pubitemid 34214484)
    • (2002) Biochemical Journal , vol.362 , Issue.2 , pp. 413-422
    • Alpert, E.1    Gruzman, A.2    Totary, H.3    Kaiser, N.4    Reich, R.5    Sasson, S.6
  • 128
    • 78650173914 scopus 로고    scopus 로고
    • Differential expression and localization of 12/15 lipoxygenases in adipose tissue in human obese subjects
    • A.D. Dobrian, D.C. Lieb, and O. Ma Differential expression and localization of 12/15 lipoxygenases in adipose tissue in human obese subjects Biochem Biophys Res Commun 403 2010 485 490
    • (2010) Biochem Biophys Res Commun , vol.403 , pp. 485-490
    • Dobrian, A.D.1    Lieb, D.C.2    Ma, O.3
  • 129
    • 33644621593 scopus 로고    scopus 로고
    • ALOX5AP expression, but not gene haplotypes, is associated with obesity and insulin resistance
    • M. Kaaman, M. Ryden, and T. Axelsson ALOX5AP expression, but not gene haplotypes, is associated with obesity and insulin resistance Int J Obes 30 2006 447 452
    • (2006) Int J Obes , vol.30 , pp. 447-452
    • Kaaman, M.1    Ryden, M.2    Axelsson, T.3
  • 131
    • 47649096529 scopus 로고    scopus 로고
    • Association of genetic variants with atherothrombotic cerebral infarction in Japanese individuals with metabolic syndrome
    • Y. Yamada, K. Kato, and M. Oguri Association of genetic variants with atherothrombotic cerebral infarction in Japanese individuals with metabolic syndrome Int J Mol Med 21 2008 801 808
    • (2008) Int J Mol Med , vol.21 , pp. 801-808
    • Yamada, Y.1    Kato, K.2    Oguri, M.3
  • 132
    • 67649419050 scopus 로고    scopus 로고
    • Association of genetic variants with chronic kidney disease in Japanese individuals with type 2 diabetes mellitus
    • T. Yoshida, K. Kato, and K. Yokoi Association of genetic variants with chronic kidney disease in Japanese individuals with type 2 diabetes mellitus Int J Mol Med 23 2009 529 537
    • (2009) Int J Mol Med , vol.23 , pp. 529-537
    • Yoshida, T.1    Kato, K.2    Yokoi, K.3
  • 134
    • 77953519631 scopus 로고    scopus 로고
    • Human lipoxygenase pathway gene variation and association with markers of subclinical atherosclerosis in the diabetes heart study
    • [Epub ahead of print]
    • K.P. Burdon, M.E. Rudock, and A.B. Lehtinen Human lipoxygenase pathway gene variation and association with markers of subclinical atherosclerosis in the diabetes heart study Mediat Inflamm 2010 [Epub ahead of print]
    • (2010) Mediat Inflamm
    • Burdon, K.P.1    Rudock, M.E.2    Lehtinen, A.B.3
  • 135
    • 0036077019 scopus 로고    scopus 로고
    • Effect of hyperinsulinemia and type 2 diabetes-like hyperglycemia on expression of hepatic cytochrome P450 and glutathione S-transferase isoforms in a New Zealand obese-derived mouse backcross population
    • DOI 10.1124/jpet.102.033553
    • G.J. Pass, W. Becker, and R. Kluge Effect of hyperinsulinemia and type 2 diabetes-like hyperglycemia on expression of hepatic cytochrome P450 and glutathione s-transferase isoforms in a New Zealand obese-derived mouse backcross population J Pharmacol Exp Ther 302 2002 442 450 (Pubitemid 34787206)
    • (2002) Journal of Pharmacology and Experimental Therapeutics , vol.302 , Issue.2 , pp. 442-450
    • Pass, G.J.1    Becker, W.2    Kluge, R.3    Linnartz, K.4    Plum, L.5    Giesen, K.6    Joost, H.-G.7
  • 136
    • 19944424115 scopus 로고    scopus 로고
    • Decreased epoxygenase and increased epoxide hydrolase expression in the mesenteric artery of obese Zucker rats
    • X. Zhao, A. Dey, and O.P. Romanko Decreased epoxygenase and increased epoxide hydrolase expression in the mesenteric artery of obese Zucker rats Am J Physiol 288 2005 R188 R196
    • (2005) Am J Physiol , vol.288
    • Zhao, X.1    Dey, A.2    Romanko, O.P.3
  • 137
    • 78649601760 scopus 로고    scopus 로고
    • Expression and functional analysis of hepatic cytochromes P450, nuclear receptors, and membrane transporters in 10- and 25-week-old db/db mice
    • J.L. Lam, Y. Jiang, and T. Zhang Expression and functional analysis of hepatic cytochromes P450, nuclear receptors, and membrane transporters in 10- and 25-week-old db/db mice Drug Metab Dispos 38 2010 2252 2258
    • (2010) Drug Metab Dispos , vol.38 , pp. 2252-2258
    • Lam, J.L.1    Jiang, Y.2    Zhang, T.3
  • 139
    • 0032553545 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor controls the hepatic CYP4A induction adaptive response to starvation and diabetes
    • DOI 10.1074/jbc.273.47.31581
    • D.L. Kroetz, P. Yook, and P. Costet Peroxisome proliferator-activated receptor alpha controls the hepatic CYP4A induction adaptive response to starvation and diabetes J Biol Chem 273 1998 31581 31589 (Pubitemid 28533182)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.47 , pp. 31581-31589
    • Kroetz, D.L.1    Yook, P.2    Costet, P.3    Bianchi, P.4    Pineau, T.5
  • 140
    • 66049095932 scopus 로고    scopus 로고
    • Glomerular 20-HETE, EETs, and TGF-beta1 in diabetic nephropathy
    • P. Luo, Y. Zhou, and H.H. Chang Glomerular 20-HETE, EETs, and TGF-beta1 in diabetic nephropathy Am J Physiol 296 2009 F556 F563
    • (2009) Am J Physiol , vol.296
    • Luo, P.1    Zhou, Y.2    Chang, H.H.3
  • 141
    • 0033779422 scopus 로고    scopus 로고
    • Cytochrome P450 activity and endothelial dysfunction in insulin resistance
    • P.V. Katakam, M. Hoenig, and H.R. Ujhelyi Cytochrome P450 activity and endothelial dysfunction in insulin resistance J Vasc Res 37 2000 426 434
    • (2000) J Vasc Res , vol.37 , pp. 426-434
    • Katakam, P.V.1    Hoenig, M.2    Ujhelyi, H.R.3
  • 142
    • 57049119170 scopus 로고    scopus 로고
    • Role of EDHF in type 2 diabetes-induced endothelial dysfunction
    • Y. Park, S. Capobianco, and X. Gao Role of EDHF in type 2 diabetes-induced endothelial dysfunction Am J Physiol 295 2008 H1982 H1988
    • (2008) Am J Physiol , vol.295
    • Park, Y.1    Capobianco, S.2    Gao, X.3
  • 143
    • 77951189487 scopus 로고    scopus 로고
    • Increased CYP2J3 expression reduces insulin resistance in fructose-treated rats and db/db mice
    • X. Xu, C.X. Zhao, and L. Wang Increased CYP2J3 expression reduces insulin resistance in fructose-treated rats and db/db mice Diabetes 59 2010 997 1005
    • (2010) Diabetes , vol.59 , pp. 997-1005
    • Xu, X.1    Zhao, C.X.2    Wang, L.3
  • 144
    • 78951491442 scopus 로고    scopus 로고
    • Inhibition of soluble epoxide hydrolase attenuates endothelial dysfunction in animal models of diabetes, obesity and hypertension
    • L.N. Zhang, J. Vincelette, and D. Chen Inhibition of soluble epoxide hydrolase attenuates endothelial dysfunction in animal models of diabetes, obesity and hypertension Eur J Pharmacol 654 2011 68 74
    • (2011) Eur J Pharmacol , vol.654 , pp. 68-74
    • Zhang, L.N.1    Vincelette, J.2    Chen, D.3
  • 145
    • 79960840685 scopus 로고    scopus 로고
    • Inhibition of soluble epoxide hydrolase reduces food intake and increases metabolic rate in obese mice
    • [Epub ahead of print]
    • J.M. Do Carmo, A.A. da Silva, and J. Morgan Inhibition of soluble epoxide hydrolase reduces food intake and increases metabolic rate in obese mice Nutr Metab Cardiovasc Dis 2010 [Epub ahead of print]
    • (2010) Nutr Metab Cardiovasc Dis
    • Do Carmo, J.M.1    Da Silva, A.A.2    Morgan, J.3
  • 146
    • 73349106519 scopus 로고    scopus 로고
    • Epoxyeicosatrienoic acid agonist rescues the metabolic syndrome phenotype of HO-2-null mice
    • K. Sodhi, K. Inoue, and K.H. Gotlinger Epoxyeicosatrienoic acid agonist rescues the metabolic syndrome phenotype of HO-2-null mice J Pharmcol Exp Ther 331 2009 906 916
    • (2009) J Pharmcol Exp Ther , vol.331 , pp. 906-916
    • Sodhi, K.1    Inoue, K.2    Gotlinger, K.H.3
  • 147
    • 45149118530 scopus 로고    scopus 로고
    • PPAR-alpha agonist fenofibrate induces renal CYP enzymes and reduces blood pressure and glomerular hypertrophy in Zucker diabetic fatty rats
    • X. Zhao, and L.Y. Li PPAR-alpha agonist fenofibrate induces renal CYP enzymes and reduces blood pressure and glomerular hypertrophy in Zucker diabetic fatty rats Am J Nephrol 28 2008 98 606
    • (2008) Am J Nephrol , vol.28 , pp. 98-606
    • Zhao, X.1    Li, L.Y.2
  • 148
    • 35548938948 scopus 로고    scopus 로고
    • Role of cytochrome P450 metabolites of arachidonic acid in regulation of corporal smooth muscle tone in diabetic and older rats
    • DOI 10.1016/j.vph.2007.08.002, PII S1537189107001231
    • M.H. Yousif, and I.F. Benter Role of cytochrome P450 metabolites of arachidonic acid in regulation of corporal smooth muscle tone in diabetic and older rats Vascul Pharmacol 47 2007 281 287 (Pubitemid 350008129)
    • (2007) Vascular Pharmacology , vol.47 , Issue.5-6 , pp. 281-287
    • Yousif, M.H.M.1    Benter, I.F.2
  • 150
    • 79960965105 scopus 로고    scopus 로고
    • Influence of CYP2C9 gene polymorphisms on response to glibenclamide in type 2 diabetes mellitus patients
    • [Epub ahead of print]
    • A. Surendiran, S.C. Pradhan, and A. Agrawal Influence of CYP2C9 gene polymorphisms on response to glibenclamide in type 2 diabetes mellitus patients Eur J Clin Pharmacol 2011 [Epub ahead of print]
    • (2011) Eur J Clin Pharmacol
    • Surendiran, A.1    Pradhan, S.C.2    Agrawal, A.3
  • 151
    • 72849111539 scopus 로고    scopus 로고
    • Loss-of-function CYP2C9 variants improve therapeutic response to sulfonylureas in type 2 diabetes: A Go-DARTS study
    • K. Zhou, L. Donnelly, and L. Burch Loss-of-function CYP2C9 variants improve therapeutic response to sulfonylureas in type 2 diabetes: a Go-DARTS study Clin Pharmacol Ther 87 2010 52 56
    • (2010) Clin Pharmacol Ther , vol.87 , pp. 52-56
    • Zhou, K.1    Donnelly, L.2    Burch, L.3
  • 152
    • 70649097093 scopus 로고    scopus 로고
    • Presence of CYP2C9*3 allele increases risk for hypoglycemia in type 2 diabetic patients treated with sulfonylureas
    • G. Ragia, I. Petridis, and A. Tavridou Presence of CYP2C9*3 allele increases risk for hypoglycemia in type 2 diabetic patients treated with sulfonylureas Pharmacogenomics 10 2009 1781 1787
    • (2009) Pharmacogenomics , vol.10 , pp. 1781-1787
    • Ragia, G.1    Petridis, I.2    Tavridou, A.3
  • 153
    • 77957368486 scopus 로고    scopus 로고
    • Prevalence of CYP450 gene variations in patients with type 2 diabetes
    • A. Weise, S. Prause, and M. Eidens Prevalence of CYP450 gene variations in patients with type 2 diabetes Clin Lab 56 2010 311 318
    • (2010) Clin Lab , vol.56 , pp. 311-318
    • Weise, A.1    Prause, S.2    Eidens, M.3
  • 154
    • 77953668391 scopus 로고    scopus 로고
    • Genetic variation in the G-50T polymorphism of the cytochrome P450 epoxygenase CYP2J2 gene and the risk of younger onset type 2 diabetes among Chinese population: Potential interaction with body mass index and family history
    • C.P. Wang, W.C. Hung, and T.H. Yu Genetic variation in the G-50T polymorphism of the cytochrome P450 epoxygenase CYP2J2 gene and the risk of younger onset type 2 diabetes among Chinese population: potential interaction with body mass index and family history Exp Clin Endocrinol Diabetes 118 2010 346 352
    • (2010) Exp Clin Endocrinol Diabetes , vol.118 , pp. 346-352
    • Wang, C.P.1    Hung, W.C.2    Yu, T.H.3
  • 155
    • 78649710075 scopus 로고    scopus 로고
    • Effect of CYP2C9 polymorphisms on prescribed dose and time-to-stable dose of sulfonylureas in primary care patients with type 2 diabetes mellitus
    • J.J. Swen, J.A. Wessels, and A. Krabben Effect of CYP2C9 polymorphisms on prescribed dose and time-to-stable dose of sulfonylureas in primary care patients with type 2 diabetes mellitus Pharmacogenomics 11 2010 1517 1523
    • (2010) Pharmacogenomics , vol.11 , pp. 1517-1523
    • Swen, J.J.1    Wessels, J.A.2    Krabben, A.3
  • 156
    • 78649799516 scopus 로고    scopus 로고
    • Analysis of CYP2C9*2, CYP2C19*2, and CYP2D6*4 polymorphisms in patients with type 2 diabetes mellitus
    • S. Semiz, T. Dujic, and B. Ostanek Analysis of CYP2C9*2, CYP2C19*2, and CYP2D6*4 polymorphisms in patients with type 2 diabetes mellitus Bosn J Basic Med Sci 10 2010 287 291
    • (2010) Bosn J Basic Med Sci , vol.10 , pp. 287-291
    • Semiz, S.1    Dujic, T.2    Ostanek, B.3
  • 157
    • 33846954400 scopus 로고    scopus 로고
    • CYP2C9 variant modifies blood pressure-lowering response to losartan in type 1 diabetic patients with nephropathy
    • M. Lajer, L. Tarnow, and S. Andersen CYP2C9 variant modifies blood pressure-lowering response to losartan in type 1 diabetic patients with nephropathy Diabet Med 24 2007 323 325
    • (2007) Diabet Med , vol.24 , pp. 323-325
    • Lajer, M.1    Tarnow, L.2    Andersen, S.3
  • 159
    • 33746830525 scopus 로고    scopus 로고
    • N-3 Polyunsaturated fatty acids, inflammation, and inflammatory diseases
    • P.C. Calder n-3 Polyunsaturated fatty acids, inflammation, and inflammatory diseases Am J Clin Nutr 83 2006 S1505 S1519
    • (2006) Am J Clin Nutr , vol.83
    • Calder, P.C.1
  • 160
    • 78649451203 scopus 로고    scopus 로고
    • Role of cytochrome P450 enzymes in the bioactivation of polyunsaturated fatty acids
    • A. Konkel, and W.H. Schunck Role of cytochrome P450 enzymes in the bioactivation of polyunsaturated fatty acids Biochim Biophys Acta 1814 2011 210 222
    • (2011) Biochim Biophys Acta , vol.1814 , pp. 210-222
    • Konkel, A.1    Schunck, W.H.2
  • 161
    • 77449141236 scopus 로고    scopus 로고
    • Cellular production of n-3 PUFAs and reduction of n-6 to n-3 ratios in the pancreatic beta-cells and islets enhance insulin secretion and confer protection against cytokine-induced cell death
    • D. Wei, J. Li, and M. Shen Cellular production of n-3 PUFAs and reduction of n-6 to n-3 ratios in the pancreatic beta-cells and islets enhance insulin secretion and confer protection against cytokine-induced cell death Diabetes 59 2010 471 478
    • (2010) Diabetes , vol.59 , pp. 471-478
    • Wei, D.1    Li, J.2    Shen, M.3
  • 162
    • 79953174254 scopus 로고    scopus 로고
    • High pancreatic n-3 fatty acids prevent STZ-induced diabetes in fat-1 mice: Inflammatory pathway inhibition
    • J. Bellenger, S. Bellenger, and A. Bataille High pancreatic n-3 fatty acids prevent STZ-induced diabetes in fat-1 mice: Inflammatory pathway inhibition Diabetes 60 2011 1090 1099
    • (2011) Diabetes , vol.60 , pp. 1090-1099
    • Bellenger, J.1    Bellenger, S.2    Bataille, A.3
  • 163
  • 164
    • 67649363782 scopus 로고    scopus 로고
    • Obesity-induced insulin resistance and hepatic steatosis are alleviated by omega-3 fatty acids: A role for resolvins and protectins
    • A. Gonzalez-Periz, R. Horrillo, and N. Ferre Obesity-induced insulin resistance and hepatic steatosis are alleviated by omega-3 fatty acids: A role for resolvins and protectins FASEB J 23 2009 1946 1957
    • (2009) FASEB J , vol.23 , pp. 1946-1957
    • Gonzalez-Periz, A.1    Horrillo, R.2    Ferre, N.3
  • 165
    • 0032692793 scopus 로고    scopus 로고
    • Dietary fish as a major component of a weight-loss diet: Effect on serum lipids, glucose, and insulin metabolism in overweight hypertensive subjects
    • T.A. Mori, D.Q. Bao, and V. Burke Dietary fish as a major component of a weight-loss diet: effect on serum lipids, glucose, and insulin metabolism in overweight hypertensive subjects Am J Clin Nutr 70 1999 817 825 (Pubitemid 29512906)
    • (1999) American Journal of Clinical Nutrition , vol.70 , Issue.5 , pp. 817-825
    • Mori, T.A.1    Bao, D.Q.2    Burke, V.3    Puddey, I.B.4    Watts, G.F.5    Beilin, L.J.6
  • 166
    • 0036825071 scopus 로고    scopus 로고
    • The influence of dietary fat on insulin resistance
    • J.C. Lovejoy The influence of dietary fat on insulin resistance Curr Diab Rep 2 2002 435 440
    • (2002) Curr Diab Rep , vol.2 , pp. 435-440
    • Lovejoy, J.C.1
  • 167
    • 0029997244 scopus 로고    scopus 로고
    • Marine lipids normalize cholesteryl ester transfer in IDDM
    • DOI 10.1007/s001250050470
    • J.D. Bagdade, M. Ritter, and P.V. Subbaiah Marine lipids normalize cholesteryl ester transfer in IDDM Diabetologia 39 1996 487 491 (Pubitemid 26096301)
    • (1996) Diabetologia , vol.39 , Issue.4 , pp. 487-491
    • Bagdade, J.D.1    Ritter, M.2    Subbaiah, P.Y.3
  • 169
    • 77958464748 scopus 로고    scopus 로고
    • Discovery of potent and selective inhibitors of human reticulocyte 15-lipoxygenase-1
    • G. Rai, V. Kenyon, and A. Jadhav Discovery of potent and selective inhibitors of human reticulocyte 15-lipoxygenase-1 J Med Chem 53 2010 7392 7404
    • (2010) J Med Chem , vol.53 , pp. 7392-7404
    • Rai, G.1    Kenyon, V.2    Jadhav, A.3
  • 170
    • 77958484254 scopus 로고    scopus 로고
    • Arachidonic acid-metabolizing cytochrome P450 enzymes are targets of {omega}-3 fatty acids
    • C. Arnold, M. Markovic, and K. Blossey Arachidonic acid-metabolizing cytochrome P450 enzymes are targets of {omega}-3 fatty acids J Biol Chem 285 2010 32720 32733
    • (2010) J Biol Chem , vol.285 , pp. 32720-32733
    • Arnold, C.1    Markovic, M.2    Blossey, K.3


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