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Volumn 174, Issue 6, 2009, Pages 2086-2095

Soluble epoxide inhibition is protective against cerebral ischemia via vascular and neural protection

Author keywords

[No Author keywords available]

Indexed keywords

12 (3 ADAMANTAN 1 YLUREIDO)DODECANOIC ACID; 4 [4 (3 ADAMANTAN 1 YLUREIDO)CYCLOHEXYLOXY]BENZOIC ACID; ENALAPRIL; ENZYME INHIBITOR; EPOXIDE HYDROLASE; UNCLASSIFIED DRUG;

EID: 67049119782     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.2353/ajpath.2009.080544     Document Type: Article
Times cited : (100)

References (54)
  • 1
    • 34247867952 scopus 로고    scopus 로고
    • Cardiovascular therapeutic aspects of soluble epoxide hydrolase inhibitors
    • DOI 10.1111/j.1527-3466.2006.00169.x
    • Imig JD: Cardiovascular therapeutic aspects of soluble epoxide hydrolase inhibitors. Cardiovasc Drug Rev 2006, 24:169-188 (Pubitemid 46696923)
    • (2006) Cardiovascular Drug Reviews , vol.24 , Issue.2 , pp. 169-188
    • Imig, J.D.1
  • 2
    • 38149070234 scopus 로고    scopus 로고
    • Vascular cytochrome p450 enzymes: Physiology and pathophysiology
    • Fleming I: Vascular cytochrome p450 enzymes: physiology and pathophysiology. Trends Cardiovasc Med 2008, 18:20-25
    • (2008) Trends Cardiovasc Med , vol.18 , pp. 20-25
    • Fleming, I.1
  • 3
    • 23044439770 scopus 로고    scopus 로고
    • Hypoxic preconditioning and tolerance via hypoxia inducible factor (HIF) 1alpha-linked induction of P450 2C11 epoxygenase in astrocytes
    • DOI 10.1038/sj.jcbfm.9600085
    • Liu M, Alkayed NJ: Hypoxic preconditioning and tolerance via hypoxia inducible factor (HIF) 1alpha-linked induction of P450 2C11 epoxygenase in astrocytes. J Cereb Blood Flow Metab 2005, 25:939-948 (Pubitemid 41061709)
    • (2005) Journal of Cerebral Blood Flow and Metabolism , vol.25 , Issue.8 , pp. 939-948
    • Liu, M.1    Alkayed, N.J.2
  • 5
    • 0242720683 scopus 로고    scopus 로고
    • Epoxyeicosatrienoic acids (EETs): Metabolism and biochemical function
    • DOI 10.1016/S0163-7827(03)00049-3
    • Spector AA, Fang X, Snyder GD, Weintraub NL: Epoxyeicosatrienoic acids (EETs): metabolism and biochemical function. Prog Lipid Res 2004, 43:55-90 (Pubitemid 37433867)
    • (2004) Progress in Lipid Research , vol.43 , Issue.1 , pp. 55-90
    • Spector, A.A.1    Fang, X.2    Snyder, G.D.3    Weintraub, N.L.4
  • 6
    • 26444506849 scopus 로고    scopus 로고
    • The soluble epoxide hydrolase gene harbors sequence variation associated with susceptibility to and protection from incident ischemic stroke
    • DOI 10.1093/hmg/ddi315
    • Fornage M, Lee CR, Doris PA, Bray MS, Heiss G, Zeldin DC, Boerwinkle E: The soluble epoxide hydrolase gene harbors sequence variation associated with susceptibility to and protection from incident ischemic stroke. Hum Mol Genet 2005, 14:2829-2837 (Pubitemid 41418788)
    • (2005) Human Molecular Genetics , vol.14 , Issue.19 , pp. 2829-2837
    • Fornage, M.1    Lee, C.R.2    Doris, P.A.3    Bray, M.S.4    Heiss, G.5    Zeldin, D.C.6    Boerwinkle, E.7
  • 8
    • 33644697099 scopus 로고    scopus 로고
    • An epoxide hydrolase inhibitor, 12-(3-adamantan-1-yl-ureido)dodecanoic acid (AUDA), reduces ischemic cerebral infarct size in stroke-prone spontaneously hypertensive rats
    • DOI 10.1097/01.fjc.0000189600.74157.6d, PII 0000534420051200000019
    • Dorrance AM, Rupp N, Pollock DM, Newman JW, Hammock BD, Imig JD: An epoxide hydrolase inhibitor, 12-(3-adamantan-1-yl-ureido)dodecanoic acid (AUDA), reduces ischemic cerebral infarct size in stroke-prone spontaneously hypertensive rats. J Cardiovasc Pharmacol 2005, 46:842-848 (Pubitemid 44378259)
    • (2005) Journal of Cardiovascular Pharmacology , vol.46 , Issue.6 , pp. 842-848
    • Dorrance, A.M.1    Rupp, N.2    Pollock, D.M.3    Newman, J.W.4    Hammock, B.D.5    Imig, J.D.6
  • 9
    • 0023220984 scopus 로고
    • Dorsal cerebral collaterals of stroke-prone spontaneously hypertensive rats (SHRSP) and Wistar Kyoto rats (WKY)
    • DOI 10.1002/ar.1092180108
    • Coyle P: Dorsal cerebral collaterals of stroke-prone spontaneously hypertensive rats (SHRSP) and Wistar Kyoto rats (WKY). Anat Rec 1987, 218:40-44 (Pubitemid 17078693)
    • (1987) Anatomical Record , vol.218 , Issue.1 , pp. 40-44
    • Coyle, P.1
  • 10
    • 0020620843 scopus 로고
    • Differential outcome to middle cerebral artery occlusion in spontaneously hypertensive stroke-prone rats (SHRSP) and Wistar Kyoto (WKY) rats
    • Coyle P, Jokelainen PT: Differential outcome to middle cerebral artery occlusion in spontaneously hypertensive stroke-prone rats (SHRSP) and Wistar Kyoto (WKY) rats. Stroke 1983, 14:605-611
    • (1983) Stroke , vol.14 , pp. 605-611
    • Coyle, P.1    Jokelainen, P.T.2
  • 13
    • 34548755151 scopus 로고    scopus 로고
    • The soluble epoxide hydrolase as a pharmaceutical target for hypertension
    • DOI 10.1097/FJC.0b013e3181506445, PII 0000534420070900000002
    • Chiamvimonvat N, Ho CM, Tsai HJ, Hammock BD: The soluble epoxide hydrolase as a pharmaceutical target for hypertension. J Cardiovasc Pharmacol 2007, 50:225-237 (Pubitemid 47428969)
    • (2007) Journal of Cardiovascular Pharmacology , vol.50 , Issue.3 , pp. 225-237
    • Chiamvimonvat, N.1    Ho, C.-M.2    Tsai, H.-J.3    Hammock, B.D.4
  • 14
    • 0024494427 scopus 로고
    • Reversible middle cerebral artery occlusion without craniectomy in rats
    • Longa EZ, Weinstein PR, Carlson S, Cummins R: Reversible middle cerebral artery occlusion without craniectomy in rats. Stroke 1989, 20:84-91 (Pubitemid 19040218)
    • (1989) Stroke , vol.20 , Issue.1 , pp. 84-91
    • Longa, E.Z.1    Weinstein, P.R.2    Carlson, S.3    Cummins, R.4
  • 15
    • 0022483434 scopus 로고
    • Rat middle cerebral artery occlusion: Evaluation of the model and development of a neurologic examination
    • Bederson JB, Pitts LH, Tsuji M, Nishimura MC, Davis RL, Bartkowski H: Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination. Stroke 1986, 17:472-476 (Pubitemid 16085691)
    • (1986) Stroke , vol.17 , Issue.3 , pp. 472-476
    • Bederson, J.B.1    Pitts, L.H.2    Tsuji, M.3
  • 16
    • 0035167706 scopus 로고    scopus 로고
    • Intravenous administration of human umbilical cord blood reduces behavioral deficits after stroke in rats
    • Chen J, Sanberg PR, Li Y, Wang L, Lu M, Willing AE, Sanchez-Ramos J, Chopp M: Intravenous administration of human umbilical cord blood reduces behavioral deficits after stroke in rats. Stroke 2001, 32:2682-2688 (Pubitemid 33055324)
    • (2001) Stroke , vol.32 , Issue.11 , pp. 2682-2688
    • Chen, J.1    Sanberg, P.R.2    Li, Y.3    Wang, L.4    Lu, M.5    Willing, A.E.6    Sanchez-Ramos, J.7    Chopp, M.8
  • 18
    • 34347406444 scopus 로고    scopus 로고
    • Soluble epoxide hydrolase gene deletion is associated with increased cbf and reduced stroke damage
    • Zhang W, Kooper D, Alkayed NJ: Soluble epoxide hydrolase gene deletion is associated with increased cbf and reduced stroke damage. Stroke 2006, 37:683
    • (2006) Stroke , vol.37 , pp. 683
    • Zhang, W.1    Kooper, D.2    Alkayed, N.J.3
  • 19
    • 38549099062 scopus 로고    scopus 로고
    • Endothelial dysfunction and the development of renal injury in spontaneously hypertensive rats fed a high-fat diet
    • DOI 10.1161/HYPERTENSIONAHA.107.099499, PII 0000426820080200000031
    • Knight SF, Quigley JE, Yuan J, Roy SS, Elmarakby A, Imig JD: Endothelial dysfunction and the development of renal injury in spontaneously hypertensive rats fed a high-fat diet. Hypertension 2008, 51:352-359 (Pubitemid 351159950)
    • (2008) Hypertension , vol.51 , Issue.2 , pp. 352-359
    • Knight, S.F.1    Quigley, J.E.2    Yuan, J.3    Roy, S.S.4    Elmarakby, A.5    Imig, J.D.6
  • 22
    • 33745918021 scopus 로고    scopus 로고
    • Development of a high-throughput screen for soluble epoxide hydrolase inhibition
    • DOI 10.1016/j.ab.2006.04.045, PII S0003269706003265
    • Wolf NM, Morisseau C, Jones PD, Hock B, Hammock BD: Development of a high-throughput screen for soluble epoxide hydrolase inhibition. Anal Biochem 2006, 355:71-80 (Pubitemid 44041405)
    • (2006) Analytical Biochemistry , vol.355 , Issue.1 , pp. 71-80
    • Wolf, N.M.1    Morisseau, C.2    Jones, P.D.3    Hock, B.4    Hammock, B.D.5
  • 24
    • 33750214897 scopus 로고    scopus 로고
    • Inhibition of smooth muscle proliferation by urea-based alkanoic acids via peroxisome proliferator-activated receptor alpha-dependent repression of cyclin D1
    • DOI 10.1161/01.ATV.0000242013.29441.81, PII 0004360520061100000008
    • Ng VY, Morisseau C, Falck JR, Hammock BD, Kroetz DL: Inhibition of smooth muscle proliferation by urea-based alkanoic acids via peroxisome proliferator-activated receptor alpha-dependent repression of cyclin D1. Arterioscler Thromb Vasc Biol 2006, 26:2462-2468 (Pubitemid 44607466)
    • (2006) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.26 , Issue.11 , pp. 2462-2468
    • Ng, V.Y.1    Morisseau, C.2    Falck, J.R.3    Hammock, B.D.4    Kroetz, D.L.5
  • 25
    • 2342512834 scopus 로고    scopus 로고
    • Structural remodeling of resistance arteries in uremic hypertension
    • DOI 10.1111/j.1523-1755.2004.00591.x
    • New DI, Chesser AM, Thuraisingham RC, Yaqoob MM: Structural remodeling of resistance arteries in uremic hypertension. Kidney Int 2004, 65:1818-1825 (Pubitemid 38591031)
    • (2004) Kidney International , vol.65 , Issue.5 , pp. 1818-1825
    • New, D.I.1    Chesser, A.M.2    Thuraisingham, R.C.3    Yaqoob, M.M.4
  • 27
    • 9644268873 scopus 로고    scopus 로고
    • Characterization of regional cerebral blood flow and expression of angiogenic growth factors in the frontal cortex of juvenile male SHRSP and SHR
    • DOI 10.1016/j.brainres.2004.10.004, PII S0006899304016427
    • Jesmin S, Togashi H, Mowa CN, Ueno K, Yamaguchi T, Shibayama A, Miyauchi T, Sakuma I, Yoshioka M: Characterization of regional cerebral blood flow and expression of angiogenic growth factors in the frontal cortex of juvenile male SHRSP and SHR. Brain Res 2004, 1030:172-182 (Pubitemid 39574950)
    • (2004) Brain Research , vol.1030 , Issue.2 , pp. 172-182
    • Jesmin, S.1    Togashi, H.2    Mowa, C.N.3    Ueno, K.-I.4    Yamaguchi, T.5    Shibayama, A.6    Miyauchi, T.7    Sakuma, I.8    Yoshioka, M.9
  • 28
    • 4344684088 scopus 로고    scopus 로고
    • Gonadal hormones and frontocortical expression of vascular endothelial growth factor in male stroke-prone, spontaneously hypertensive rats, a model for attention-deficit/hyperactivity disorder
    • DOI 10.1210/en.2004-0487
    • Jesmin S, Togashi H, Sakuma I, Mowa CN, Ueno K, Yamaguchi T, Yoshioka M, Kitabatake A: Gonadal hormones and frontocortical expression of vascular endothelial growth factor in male stroke-prone, spontaneously hypertensive rats, a model for attention-deficit/hyperactivity disorder. Endocrinology 2004, 145:4330-4343 (Pubitemid 39120583)
    • (2004) Endocrinology , vol.145 , Issue.9 , pp. 4330-4343
    • Jesmin, S.1    Togashi, H.2    Sakuma, I.3    Mowa, C.N.4    Ueno, K.-I.5    Yamaguchi, T.6    Yoshioka, M.7    Kitabatake, A.8
  • 29
    • 31844440677 scopus 로고    scopus 로고
    • High-throughput pharmacokinetic method: Cassette dosing in mice associated with minuscule serial bleedings and LC/MS/MS analysis
    • DOI 10.1016/j.aca.2005.11.049, PII S0003267005019124
    • Watanabe T, Schulz D, Morisseau C, Hammock BD: High-throughput pharmacokinetic method: cassette dosing in mice associated with minuscule serial bleedings and LC/MS/MS analysis. Anal Chim Acta 2006, 559:37-44 (Pubitemid 43184285)
    • (2006) Analytica Chimica Acta , vol.559 , Issue.1 , pp. 37-44
    • Watanabe, T.1    Schulz, D.2    Morisseau, C.3    Hammock, B.D.4
  • 33
    • 0035725998 scopus 로고    scopus 로고
    • Cytochrome P450 epoxygenase metabolism of arachidonic acid inhibits apoptosis
    • DOI 10.1128/MCB.21.18.6322-6331.2001
    • Chen JK, Capdevila J, Harris RC: Cytochrome p450 epoxygenase metabolism of arachidonic acid inhibits apoptosis. Mol Cell Biol 2001, 21:6322-6331 (Pubitemid 34263530)
    • (2001) Molecular and Cellular Biology , vol.21 , Issue.18 , pp. 6322-6331
    • Chen, J.-K.1    Capdevila, J.2    Harris, R.C.3
  • 34
    • 0034923447 scopus 로고    scopus 로고
    • Overexpression of cytochrome P450 CYP2J2 protects against hypoxia-reoxygenation injury in cultured bovine aortic endothelial cells
    • Yang B, Graham L, Dikalov S, Mason RP, Falck JR, Liao JK, Zeldin DC: Overexpression of cytochrome P450 CYP2J2 protects against hypoxia-reoxygenation injury in cultured bovine aortic endothelial cells. Mol Pharmacol 2001, 60:310-320 (Pubitemid 32678296)
    • (2001) Molecular Pharmacology , vol.60 , Issue.2 , pp. 310-320
    • Yang, B.1    Graham, L.2    Dikalov, S.3    Mason, R.P.4    Falck, J.R.5    Liao, J.K.6    Zeldin, D.C.7
  • 37
    • 0033528649 scopus 로고    scopus 로고
    • Differential regulation of apoptosis-related genes in resistant and vulnerable subfields of the rat epileptic hippocampus
    • DOI 10.1016/S0169-328X(99)00060-1, PII S0169328X99000601
    • Becker AJ, Gillardon F, Blumcke I, Langendorfer D, Beck H, Wiestler OD: Differential regulation of apoptosis-related genes in resistant and vulnerable subfields of the rat epileptic hippocampus. Brain Res Mol Brain Res 1999, 67:172-176 (Pubitemid 29170080)
    • (1999) Molecular Brain Research , vol.67 , Issue.1 , pp. 172-176
    • Becker, A.J.1    Gillardon, F.2    Blumcke, I.3    Langendorfer, D.4    Beck, H.5    Wiestler, O.D.6
  • 38
    • 0035895994 scopus 로고    scopus 로고
    • Inhibition of JNK by Overexpression of the JNK Binding Domain of JIP-1 Prevents Apoptosis in Sympathetic Neurons
    • DOI 10.1074/jbc.C000815200
    • Harding TC, Xue L, Bienemann A, Haywood D, Dickens M, Tolkovsky AM, Uney JB: Inhibition of JNK by overexpression of the JNL binding domain of JIP-1 prevents apoptosis in sympathetic neurons. J Biol Chem 2001, 276:4531-4534 (Pubitemid 37371330)
    • (2001) Journal of Biological Chemistry , vol.276 , Issue.7 , pp. 4531-4534
    • Harding, T.C.1    Xue, L.2    Bienemann, A.3    Haywood, D.4    Dickens, M.5    Tolkovsky, A.M.6    Uney, J.B.7
  • 42
    • 33644858948 scopus 로고    scopus 로고
    • Reduction of caspase-8 and -9 cleavage is associated with increased c-FLIP and increased binding of Apaf-1 and Hsp70 after neonatal hypoxic/ischemic injury in mice overexpressing Hsp70
    • DOI 10.1161/01.STR.0000199057.00365.20, PII 0000767020060200000078
    • Matsumori Y, Northington FJ, Hong SM, Kayama T, Sheldon RA, Vexler ZS, Ferriero DM, Weinstein PR, Liu J: Reduction of caspase-8 and -9 cleavage is associated with increased c-FLIP and increased binding of Apaf-1 and Hsp70 after neonatal hypoxic/ischemic injury in mice overexpressing Hsp70. Stroke 2006, 37:507-512 (Pubitemid 43732015)
    • (2006) Stroke , vol.37 , Issue.2 , pp. 507-512
    • Matsumori, Y.1    Northington, F.J.2    Hong, S.M.3    Kayama, T.4    Sheldon, R.A.5    Vexler, Z.S.6    Ferriero, D.M.7    Weinstein, P.R.8    Liu, J.9
  • 45
    • 34848827935 scopus 로고    scopus 로고
    • Epoxyeicosatrienoic acids induce growth inhibition and calpain/caspase-12 dependent apoptosis in PDGF cultured 3T6 fibroblast
    • DOI 10.1007/s10495-007-0123-3
    • Nieves D, Moreno JJ: Epoxyeicosatrienoic acids induce growth inhibition and calpain/caspase-12 dependent apoptosis in PDGF cultured 3T6 fibroblast. Apoptosis 2007, 12:1979-1988 (Pubitemid 47498231)
    • (2007) Apoptosis , vol.12 , Issue.11 , pp. 1979-1988
    • Nieves, D.1    Moreno, J.J.2
  • 46
    • 0036901546 scopus 로고    scopus 로고
    • Cerebral capillary endothelial cell mitogenesis and morphogenesis induced by astrocytic epoxyeicosatrienoic acid
    • DOI 10.1161/01.STR.0000037787.07479.9A
    • Zhang C, Harder DR: Cerebral capillary endothelial cell mitogenesis and morphogenesis induced by astrocytic epoxyeicosatrienoic Acid. Stroke 2002, 33:2957-2964 (Pubitemid 35462872)
    • (2002) Stroke , vol.33 , Issue.12 , pp. 2957-2964
    • Zhang, C.1    Harder, D.R.2
  • 47
    • 34247525219 scopus 로고    scopus 로고
    • Polymorphisms in the human soluble epoxide hydrolase gene EPHX2 linked to neuronal survival after ischemic injury
    • DOI 10.1523/JNEUROSCI.0056-07.2007
    • Koerner IP, Jacks R, DeBarber AE, Koop D, Mao P, Grant DF, Alkayed NJ: Polymorphisms in the human soluble epoxide hydrolase gene EPHX2 linked to neuronal survival after ischemic injury. J Neurosci 2007, 27:4642-4649 (Pubitemid 46663588)
    • (2007) Journal of Neuroscience , vol.27 , Issue.17 , pp. 4642-4649
    • Koerner, I.P.1    Jacks, R.2    Debarber, A.E.3    Koop, D.4    Mao, P.5    Grant, D.F.6    Alkayed, N.J.7
  • 48
    • 0035431321 scopus 로고    scopus 로고
    • Structure of the PPARalpha and -gamma ligand binding domain in complex with AZ 242; ligand selectivity and agonist activation in the PPAR family
    • DOI 10.1016/S0969-2126(01)00634-7, PII S0969212601006347
    • Cronet P, Petersen JF, Folmer R, Blomberg N, Sjoblom K, Karlsson U, Lindstedt EL, Bamberg K: Structure of the PPARalpha and -gamma ligand binding domain in complex with AZ 242; ligand selectivity and agonist activation in the PPAR family. Structure 2001, 9:699-706 (Pubitemid 32772892)
    • (2001) Structure , vol.9 , Issue.8 , pp. 699-706
    • Cronet, P.1    Petersen, J.F.W.2    Folmer, R.3    Blomberg, N.4    Sjoblom, K.5    Karlsson, U.6    Lindstedt, E.-L.7    Bamberg, K.8
  • 51
    • 33644861843 scopus 로고    scopus 로고
    • The lifetime risk of stroke: Estimates from the framingham study
    • DOI 10.1161/01.STR.0000199613.38911.b2, PII 0000767020060200000048
    • Seshadri S, Beiser A, Kelly-Hayes M, Kase CS, Au R, Kannel WB, Wolf PA: The lifetime risk of stroke: estimates from the Framingham Study. Stroke 2006, 37:345-350 (Pubitemid 43731985)
    • (2006) Stroke , vol.37 , Issue.2 , pp. 345-350
    • Seshadri, S.1    Beiser, A.2    Kelly-Hayes, M.3    Kase, C.S.4    Au, R.5    Kannel, W.B.6    Wolf, P.A.7
  • 52
    • 0027514354 scopus 로고
    • Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment
    • Adams Jr HP, Bendixen BH, Kappelle LJ, Biller J, Love BB, Gordon DL, Marsh III EE: Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment. Stroke 1993, 24:35-41
    • (1993) Stroke , vol.24 , pp. 35-41
    • Adams Jr., H.P.1    Bendixen, B.H.2    Kappelle, L.J.3    Biller, J.4    Love, B.B.5    Gordon, D.L.6    Marsh III, E.E.7


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