Expression and functional analysis of hepatic cytochromes P450, nuclear receptors, and membrane transporters in 10- and 25-week-old db/db mice

Drug Metabolism and Disposition

Volumn 38, Issue 12, 2010, Pages 2252-2258

  Lam, Justine L ^a   Jiang, Ying ^a   Zhang, Tao ^a   Zhang, Eric Y ^a   Smith, Bill J ^a  

^a PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ABCB1B PROTEIN; ABCC2 PROTEIN; BREAST CANCER RESISTANCE PROTEIN; CELL NUCLEUS RECEPTOR; CYTOCHROME P450; CYTOCHROME P450 2B10; CYTOCHROME P450 2C29; CYTOCHROME P450 2E1; CYTOCHROME P450 3A; CYTOCHROME P450 3A11; CYTOCHROME P450 4A10; MEMBRANE PROTEIN; MESSENGER RNA; NR1I2 PROTEIN; NR1I3 PROTEIN; ORGANIC ANION TRANSPORTER 4; SLCO1A1 PROTEIN; SLCO1A4 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; C57BL MOUSE; CONTROL GROUP; CONTROLLED STUDY; DIABETES MELLITUS; ENZYME ACTIVITY; GENE EXPRESSION; LIQUID CHROMATOGRAPHY; LIVER MICROSOME; MALE; MASS SPECTROMETRY; MOUSE; MOUSE STRAIN; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; REAL TIME POLYMERASE CHAIN REACTION;

AGE FACTORS; ANIMALS; BLOOD GLUCOSE; BODY WEIGHT; CYTOCHROME P-450 ENZYME SYSTEM; DIABETES MELLITUS, TYPE 2; INSULIN; LIVER; MALE; MEMBRANE TRANSPORT PROTEINS; MICE; MICE, INBRED C57BL; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RNA, MESSENGER;

ANIMALIA; MUS;

EID: 78649601760     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.110.034223     Document Type: Article

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