A natural protective mechanism against hyperglycaemia in vascular endothelial and smooth-muscle cells: Role of glucose and 12-hydroxyeicosatetraenoic acid

Biochemical Journal

Volumn 362, Issue 2, 2002, Pages 413-422

  Alpert, Evgenia ^a   Gruzman, Arie ^a   Totary, Hanan ^a   Kaiser, Nurit ^a   Reich, Reuven ^a   Sasson, Shlomo ^a  

^a HEBREW UNIVERSITY   (Israel)

Author keywords

Glucose transport; GLUT 1; Lipoxygenase; Vascular endothelial cells; Vascular smooth muscle cells

Indexed keywords

CELLS; ENZYMES; GLUCOSE; MUSCLE; OXIDATION; RNA;

VASCULAR CELLS;

BIOCHEMISTRY;

12 HYDROXYICOSATETRAENOIC ACID; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYTOCHROME P450; GLUCOSE; GLUCOSE TRANSPORTER 1; HEXOSE; ICOSANOID; LIPOXYGENASE; MESSENGER RNA; PROSTAGLANDIN F2 ALPHA; PROTEIN;

ANIMAL CELL; ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; DOWN REGULATION; ENDOTHELIUM CELL; ENZYME METABOLISM; GLUCOSE TRANSPORT; HEXOSE TRANSPORT; HYPERGLYCEMIA; NONHUMAN; PRIORITY JOURNAL; SMOOTH MUSCLE FIBER;

12-HYDROXY-5,8,10,14-EICOSATETRAENOIC ACID; ANIMALS; ANTIOXIDANTS; BIOLOGICAL TRANSPORT; CATTLE; CELL MEMBRANE; CELLS, CULTURED; ENDOTHELIUM, VASCULAR; GENE EXPRESSION REGULATION; GLUCOSE; GLUCOSE TRANSPORTER TYPE 1; HYPERGLYCEMIA; KINETICS; MONOSACCHARIDE TRANSPORT PROTEINS; MUSCLE, SMOOTH, VASCULAR; UMBELLIFERONES;

ANIMALIA; BOVINAE; SIGANUS;

EID: 0036499692     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/0264-6021:3620413     Document Type: Article

References (50)

1. Diabetes-induced endothelial dysfunction in streptozotocin-treated rats: Role of prostaglandin endoperoxides and free radicals
2. A 12-L0 product, 12-hydroxyeicosatetraenoic acid is increased in diabetes with incipient and early renal disease
3. Renin response to 12-hydroxyeicosatetraenoic acid is increased in diabetic rats
4. Antiproliferative effect of esculetin on vascular smooth muscle cells: Possible roles of signal transduction pathways
5. Increased levels of monohydroxy metabolites of arachidonic and linoleic acids in LDL and aorta from atherosclerotic rabbits
6. Selective conversion and esterification ol monohydroxyeicosatetraenoic acids by human vascular smooth muscle cells: Relevance to smooth muscle cell proliferation
7. Vascular smooth muscle cells exhibit increased growth in response to elevated glucose
8. The mitogenic effects of 15-and 12-hyroxyeicosatetraenoic acids on endothelial cells may be mediated via diacylglycerol kinase inhibition
9. Molecular cloning of the human platelet 12-lipoxygenase
10. Molecular cloning and expression of human arachidonate 12-lipoxygenase
11. A leukocyte-type 12-lipoxygenase is expressed in human vascular and mononuclear cells: Evidence for upregulation by angiotensin II
12. Elevated glucose and angiotensin II increase 12-lipoxygenase activity and expression in porcine aortic smooth muscle cells
13. Elevated glucose alters eicosanoids release from porcine aortic endothelial cells
14. Differential regulation of glucose transport and transporters by glucose in vascular endothelial and smooth muscle cells
15. Role of lipoxygenase in the regulation of glucose transport in aortic vascular cells
16. Substrate autoregulation of glucose transport: Hexose-6-phosphate mediates the cellular distribution of glucose transporters
17. Regulation by metformin of the hexose transport system in vascular endothelial and smooth muscle cells
18. Expression of RNA from developmentally important genes in preimplantation bovine embryos produced in TCM supplemented with BSA
19. Formation of 6-oxoprostaglandin F1α, 6, 15-dioxoprostaglandin F1α, and monohydroxyeicosatetraenoic acids from arachidonic acid by fetal call aorta and ductus arteriosus
20. Induction of monocyte binding to endothelial cells by MM-LDL: Role of lipoxygenase metabolites
21. 2-isoprostanes using gas chromatography-mass spectrometry
22. Chronic effects of glucose and insulin signalling in A-1O vascular smooth muscle cells
23. Forebrain endothelium expresses GLUT4, the insulin-responsive glucose transporter
24. The inhibition of mammalian 15-lipoxygenase by the anti-inflammatory drug ebselen: Dual type mechanism involving covalent linkage and alteration of iron ligand sphere
25. Lipoxygenase inhibitors block PDGF-induced mitogenesis: A MAPK-independent mechanism that blocks fos and egr
26. L-663,536 (MK-886) (3-[1-(4-chlorobenzyl)-3-t-butyl-thio-5-isopropylindol-2-yl]-2,2 dimethylpropanoic acid), a novel, orally active leukotriene biosynthesis inhibitor
27. Caffeic acid is a selective inhibitor for leukotriene biosynthesis
28. Effects of baicalein and esculetin on transduction signals and growth factors expression in T-lymphoid leukemia cells
29. Activity of nimesulide on constitutive and inducible cyclooxygenases
30. Cytochrome P-450-dependent oxygenation of arachidonic acid to hydroxyeicosatetraenoic acids
31. + channel and vascular tone in renal arterioles
32. 2-isoprostanes) are formed in situ on phospholipids
33. 2-isoprostane in vascular smooth muscle cells by elevated glucose and growth factors
34. Platelet-derived growth factor BB mediated regulation of 12-lipoxygenase in porcine aortic smooth muscle cells
35. Regulation of expression of glucose transporters by glucose: A review of studies in vivo and in cell cultures
36. Antioxidant activity of nimesulide and its main metabolites
37. Selective inhibition of arachidonate 5-lipoxygenase by novel acetohydroxamic acids: Biochemical assessment in vitro and ex vivo
38. Mammalian 15-lipoxygenase. Enzymatic properties and biological implications
39. Suppression of hydrogen peroxide-induced mammalian cytotoxicity by nordihydroguaiaretic acid
40. Selective inhibition of lipoxygenase by esculetin
41. 2a, a potent agonist of vascular thromboxane/endoperoxide receptor, is a platelet thromboxane/endoperoxide receptor antagonist
42. Interleukin-1 increases 15-hydroxyeicosatetraenoic acid formation in cultured human endothelial cells
43. Possible inhibitory function of endogenous 15-hydroxyeicosatetraenoic acid on prostacyclin formation in bovine aortic endothelial cells
44. Cultured bovine coronary arterial endothelial cells synthesize HETEs and prostacyclin
45. Formation of 11-hydroxyeicosatetraenoic acid and 15-hydroxyeicosatetraenoic acid in human umbilical arteries is catalyzed by cyclooxygenase
46. Endothelium is required for 12-hydroxyeicosatetraenoic acid-induced vasoconstriction
47. A 12(S)-HETE receptor in Lewis lung carcinoma cells
48. Fatty acids, eicosanoids and hypolipidemic agents identified as ligands of proliferator-activated receptors by CARLA
49. Formation and actions of 20-hydroxyeicosatetraenoic acid in rat renal arterioles
50. Mono(S)hydroxy fatty acids: Novel ligands for cytosolic actin