Arachidonic acid-metabolizing cytochrome P450 enzymes are targets of ω-3 fatty acids

Journal of Biological Chemistry

Volumn 285, Issue 43, 2010, Pages 32720-32733

  Arnold, Cosima ^a   Markovic, Marija ^a   Blossey, Katrin ^b   Wallukat, Gerd ^a   Fischer, Robert ^c   Dechend, Ralf ^c   Konkel, Anne ^a   Von Schacky, Clemens ^d   Luft, Friedrich C ^a,c   Muller, Dominik N ^a   Rothe, Michael ^b   Schunck, Wolf Hagen ^a  

^a MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^b LIPIDOMIX GMBH   (Germany)

^c CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^d Omegametrix GmbH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ARACHIDONIC ACIDS; CARDIO-VASCULAR DISEASE; CYTOCHROME P450; DOCOSAHEXAENOIC ACID; DOUBLE BONDS; EICOSAPENTAENOIC ACID; EPOXYEICOSATRIENOIC ACIDS; HYDROXY METABOLITES; ISOFORMS; MEMBRANE PHOSPHOLIPIDS; METABOLITE PROFILES; NANOMOLAR CONCENTRATION; NEONATAL RAT CARDIOMYOCYTES; REGIO-SELECTIVE;

BIOMOLECULES; CATALYSTS; ENVIRONMENTAL PROTECTION AGENCY; ENZYMES; METABOLISM; METABOLITES; PHOSPHOLIPIDS;

FATTY ACIDS;

17,18 EPOXYEICOSATETRAENOIC ACID; 19,20 EPOXYDOCOSAPENTAENOIC ACID; ARACHIDONIC ACID; CALCIUM ION; CYTOCHROME P450; CYTOCHROME P450 2C; CYTOCHROME P450 4A; DOCOSAHEXAENOIC ACID; EPOXYICOSATRIENOIC ACID; ICOSAPENTAENOIC ACID; MEMBRANE PHOSPHOLIPID; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARDIOVASCULAR EFFECT; CATALYSIS; CONTROLLED STUDY; DIET SUPPLEMENTATION; ENZYME ACTIVITY; ENZYME METABOLISM; FATTY ACID METABOLISM; HEART MUSCLE CELL; IN VITRO STUDY; KIDNEY MICROSOME; LIVER MICROSOME; MALE; METABOLITE; MOLECULAR CLONING; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; ANTI-ARRHYTHMIA AGENTS; ARACHIDONIC ACID; CALCIUM; CARDIOVASCULAR DISEASES; CYTOCHROME P-450 ENZYME SYSTEM; DOCOSAHEXAENOIC ACIDS; EICOSAPENTAENOIC ACID; HUMANS; ISOENZYMES; MICE; MYOCYTES, CARDIAC; RATS; RATS, SPRAGUE-DAWLEY;

RATTUS;

EID: 77958484254     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.118406     Document Type: Article

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