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Volumn 459, Issue 6, 2010, Pages 941-950

Vasoconstrictor prostanoids

Author keywords

Aging; Diabetes; EDCF; Endothelium dependent contraction; Hypertension; TP receptors

Indexed keywords

ARACHIDONIC ACID; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; ENDOTHELIUM DERIVED CONSTRICTING FACTOR; PROSTAGLANDIN SYNTHASE; PROSTANOID; PROSTANOID RECEPTOR; PROSTAGLANDIN; THROMBOXANE RECEPTOR; VASOCONSTRICTOR AGENT;

EID: 77955284097     PISSN: 00316768     EISSN: 14322013     Source Type: Journal    
DOI: 10.1007/s00424-010-0812-6     Document Type: Review
Times cited : (91)

References (107)
  • 1
    • 34248662090 scopus 로고    scopus 로고
    • Fenofibrate improves age-related endothelial dysfunction in rat resistance arteries
    • Alvarez de Sotomayor M, Mingorance C, Andriantsitohaina R (2007) Fenofibrate improves age-related endothelial dysfunction in rat resistance arteries. Atherosclerosis 193:112-120
    • (2007) Atherosclerosis , vol.193 , pp. 112-120
    • Alvarez De Sotomayor, M.1    Mingorance, C.2    Andriantsitohaina, R.3
  • 2
    • 17144400378 scopus 로고    scopus 로고
    • Hypertension increases the participation of vasoconstrictor prostanoids from cyclooxygenase-2 in phenylephrine responses
    • Alvarez Y, Briones AM, Balfagón G, Alonso MJ, Salaices M (2005) Hypertension increases the participation of vasoconstrictor prostanoids from cyclooxygenase-2 in phenylephrine responses. J Hypertens 23:767-777
    • (2005) J Hypertens , vol.23 , pp. 767-777
    • Alvarez, Y.1    Briones, A.M.2    Balfagón, G.3    Alonso, M.J.4    Salaices, M.5
  • 3
    • 33846397764 scopus 로고    scopus 로고
    • Effects of endothelin receptor blockade on hypervasoreactivity in streptozotocin-diabetic rats: Vessel-specific involvement of thromboxane A2
    • Arikawa E, Cheung C, Sekirov I, Battell ML, Yuen VG, McNeill JH (2006) Effects of endothelin receptor blockade on hypervasoreactivity in streptozotocin-diabetic rats: vessel-specific involvement of thromboxane A2. Can J Physiol Pharmacol 84:823-833
    • (2006) Can J Physiol Pharmacol , vol.84 , pp. 823-833
    • Arikawa, E.1    Cheung, C.2    Sekirov, I.3    Battell, M.L.4    Yuen, V.G.5    McNeill, J.H.6
  • 4
    • 0024402398 scopus 로고
    • Contractions to oxygen-derived free radicals are augmented in aorta of the spontaneously hypertensive rat
    • Auch-Schwelk W, Katusic ZS, Vanhoutte PM (1989) Contractions to oxygen-derived free radicals are augmented in aorta of the spontaneously hypertensive rat. Hypertension 13:859-864
    • (1989) Hypertension , vol.13 , pp. 859-864
    • Auch-Schwelk, W.1    Katusic, Z.S.2    Vanhoutte, P.M.3
  • 5
    • 0025440112 scopus 로고
    • Thromboxane A2 receptor antagonists inhibit endothelium-dependent contractions
    • Auch-SchwelkW, Katusic ZS, Vanhoutte PM(1990) Thromboxane A2 receptor antagonists inhibit endothelium-dependent contractions. Hypertension 15:699-703
    • (1990) Hypertension , vol.15 , pp. 699-703
    • Auch-Schwelk, W.1    Katusic, Z.S.2    Vanhoutte, P.M.3
  • 6
    • 0037414069 scopus 로고    scopus 로고
    • Improved endothelial function by the thromboxane a2 receptor antagonist s 18886 in patients with coronary artery disease treated with aspirin
    • Belhassen L, Pelle G, Dubois-Rande J, Adnot S (2003) Improved endothelial function by the thromboxane a2 receptor antagonist s 18886 in patients with coronary artery disease treated with aspirin. J Am Coll Cardiol 41:1198-1204
    • (2003) J Am Coll Cardiol , vol.41 , pp. 1198-1204
    • Belhassen, L.1    Pelle, G.2    Dubois-Rande, J.3    Adnot, S.4
  • 8
    • 0345244848 scopus 로고    scopus 로고
    • Rate of vasoconstrictor prostanoids released by endothelial cells depends on cyclooxygenase-2 expression and prostaglandin i synthase activity
    • Camacho M, Lopez-Belmonte J, Vila L (1998) Rate of vasoconstrictor prostanoids released by endothelial cells depends on cyclooxygenase-2 expression and prostaglandin I synthase activity. Circ Res 83:353-365
    • (1998) Circ Res , vol.83 , pp. 353-365
    • Camacho, M.1    Lopez-Belmonte, J.2    Vila, L.3
  • 9
    • 0033925020 scopus 로고    scopus 로고
    • The thromboxane receptor antagonist S18886 but not aspirin inhibits atherogenesis in apo Edeficient mice: Evidence that eicosanoids other than thromboxane contribute to atherosclerosis
    • Cayatte AJ, Du Y, Oliver-Krasinski J, Lavielle G, Verbeuren TJ, Cohen RA (2000) The thromboxane receptor antagonist S18886 but not aspirin inhibits atherogenesis in apo Edeficient mice: evidence that eicosanoids other than thromboxane contribute to atherosclerosis. Arterioscler Thromb Vasc Biol 20:1724-1728
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 1724-1728
    • Cayatte, A.J.1    Du, Y.2    Oliver-Krasinski, J.3    Lavielle, G.4    Verbeuren, T.J.5    Cohen, R.A.6
  • 11
    • 0038266244 scopus 로고    scopus 로고
    • Does EDCF contribute to diabetic endothelial cell dysfunction?
    • Cohen RA (2002) Does EDCF contribute to diabetic endothelial cell dysfunction? Dialog Cardiovasc Med 7:225-231
    • (2002) Dialog Cardiovasc Med , vol.7 , pp. 225-231
    • Cohen, R.A.1
  • 12
    • 0035851212 scopus 로고    scopus 로고
    • Prostaglandin H synthase and vascular function
    • Davidge ST (2001) Prostaglandin H synthase and vascular function. Circ Res 89:650-660
    • (2001) Circ Res , vol.89 , pp. 650-660
    • Davidge, S.T.1
  • 13
    • 0019996073 scopus 로고
    • Heterogeneous behavior of the canine arterial and venous wall. Importance of the endothelium
    • De Mey JG, Vanhoutte PM (1982) Heterogeneous behavior of the canine arterial and venous wall. Importance of the endothelium. Circ Res 51:439-447
    • (1982) Circ Res , vol.51 , pp. 439-447
    • De Mey, J.G.1    Vanhoutte, P.M.2
  • 15
    • 0021084823 scopus 로고
    • Concentrations of prostaglandin endoperoxide synthase and prostaglandin I2 synthase in the endothelium and smooth muscle of bovine aorta
    • De Witt DL, Day JS, Sonnenburg WK, Smith WL (1983) Concentrations of prostaglandin endoperoxide synthase and prostaglandin I2 synthase in the endothelium and smooth muscle of bovine aorta. J Clin Invest 72:1882-1888
    • (1983) J Clin Invest , vol.72 , pp. 1882-1888
    • De Witt, D.L.1    Day, J.S.2    Sonnenburg, W.K.3    Smith, W.L.4
  • 16
    • 0023968630 scopus 로고
    • Primary structure of prostaglandin G/H synthase from sheep vesicular gland determined from the complementary DNA sequence
    • De Witt DL, Smith WL (1988) Primary structure of prostaglandin G/H synthase from sheep vesicular gland determined from the complementary DNA sequence. Proc Natl Acad Sci U S A 85:1412-1416
    • (1988) Proc Natl Acad Sci U S A , vol.85 , pp. 1412-1416
    • De Witt, D.L.1    Smith, W.L.2
  • 17
    • 33748421398 scopus 로고    scopus 로고
    • Endothelial dysfunction: A multifaceted disorder (The Wiggers Award Lecture)
    • Félétou M, Vanhoutte PM (2006) Endothelial dysfunction: a multifaceted disorder (The Wiggers Award Lecture). Am J Physiol Heart Circ Physiol 291:H985-H1002
    • (2006) Am J Physiol Heart Circ Physiol , vol.291
    • Félétou, M.1    Vanhoutte, P.M.2
  • 19
    • 33847117123 scopus 로고    scopus 로고
    • Balancing prostanoid activity in the human vascular system
    • Flavahan NA (2007) Balancing prostanoid activity in the human vascular system. Trends Pharmacol Sci 28:106-110
    • (2007) Trends Pharmacol Sci , vol.28 , pp. 106-110
    • Flavahan, N.A.1
  • 20
    • 0025734345 scopus 로고
    • 12-HETE inhibits the binding of PGH2/TXA2 receptor ligands in human platelets
    • Fonlupt P, Croset M, Lagarde M (1991) 12-HETE inhibits the binding of PGH2/TXA2 receptor ligands in human platelets. Thromb Res 63:239-248
    • (1991) Thromb Res , vol.63 , pp. 239-248
    • Fonlupt, P.1    Croset, M.2    Lagarde, M.3
  • 22
    • 0034111029 scopus 로고    scopus 로고
    • Oxidative stress induced by tert-butyl hydroperoxide causes vasoconstriction in the aorta from hypertensive and aged rats: Role of cyclooxygenase-2 isoform
    • Garcia-Cohen EC, Marin J, Diez-Picazo LD, Baena AB, Salaices M, Rodriguez-Martinez MA (2000) Oxidative stress induced by tert-butyl hydroperoxide causes vasoconstriction in the aorta from hypertensive and aged rats: role of cyclooxygenase-2 isoform. J Pharmacol Exp Ther 293:75-81
    • (2000) J Pharmacol Exp Ther , vol.293 , pp. 75-81
    • Garcia-Cohen, E.C.1    Marin, J.2    Diez-Picazo, L.D.3    Baena, A.B.4    Salaices, M.5    Rodriguez-Martinez, M.A.6
  • 23
    • 0029079634 scopus 로고
    • Endothelium dependent contractions are associated with both augmented expression of prostaglandin H synthase-1 and hypersensitivity to prostaglandin H2 in the SHR aorta
    • Ge T, Hughes H, Junquero DC, Wu KK, Vanhoutte PM, Boulanger CM (1995) Endothelium dependent contractions are associated with both augmented expression of prostaglandin H synthase-1 and hypersensitivity to prostaglandin H2 in the SHR aorta. Circ Res 76:1003-1010
    • (1995) Circ Res , vol.76 , pp. 1003-1010
    • Ge, T.1    Hughes, H.2    Junquero, D.C.3    Wu, K.K.4    Vanhoutte, P.M.5    Boulanger, C.M.6
  • 24
    • 35348967835 scopus 로고    scopus 로고
    • A change in the redox environment and thromboxane A2 production precede endothelial dysfunction in mice
    • Gendron ME, Thorin E (2007) A change in the redox environment and thromboxane A2 production precede endothelial dysfunction in mice. Am J Physiol Heart Circ Physiol 293:H2508-H2515
    • (2007) Am J Physiol Heart Circ Physiol , vol.293
    • Gendron, M.E.1    Thorin, E.2
  • 25
    • 27744564624 scopus 로고    scopus 로고
    • Acetylcholine-induced endothelium-dependent contractions in the SHR aorta: The Janus face of prostacyclin
    • Gluais P, Lonchampt M, Morrow JD, Vanhoutte PM, Félétou M (2005) Acetylcholine-induced endothelium-dependent contractions in the SHR aorta: the Janus face of prostacyclin. Br J Pharmacol 146:834-845
    • (2005) Br J Pharmacol , vol.146 , pp. 834-845
    • Gluais, P.1    Lonchampt, M.2    Morrow, J.D.3    Vanhoutte, P.M.4    Félétou, M.5
  • 27
    • 33846067638 scopus 로고    scopus 로고
    • Mechanisms underlying ATP-induced endothelium-dependent contractions in the SHR aorta
    • Gluais P, Vanhoutte PM, Félétou M (2007) Mechanisms underlying ATP-induced endothelium-dependent contractions in the SHR aorta. Eur J Pharmacol 556:107-114
    • (2007) Eur J Pharmacol , vol.556 , pp. 107-114
    • Gluais, P.1    Vanhoutte, P.M.2    Félétou, M.3
  • 29
    • 70350129736 scopus 로고    scopus 로고
    • Cyclooxygenase and thromboxane/ prostaglandin receptor contribute to aortic endothelium-dependent dysfunction in aging female spontaneously hypertensive rats
    • Graham DA, Rush JW (2009) Cyclooxygenase and thromboxane/ prostaglandin receptor contribute to aortic endothelium-dependent dysfunction in aging female spontaneously hypertensive rats. J Appl Physiol 107:1059-1067
    • (2009) J Appl Physiol , vol.107 , pp. 1059-1067
    • Graham, D.A.1    Rush, J.W.2
  • 30
    • 0022640297 scopus 로고
    • Superoxide anion is involved in the breakdown of endothelium-derived vascular relaxing factor
    • Gryglewski RJ, Palmer RM, Moncada S (1986) Superoxide anion is involved in the breakdown of endothelium-derived vascular relaxing factor. Nature 320:454-456
    • (1986) Nature , vol.320 , pp. 454-456
    • Gryglewski, R.J.1    Palmer, R.M.2    Moncada, S.3
  • 31
    • 0021189761 scopus 로고
    • Role of hydrogen peroxide in the neutrophil-mediated release of prostacyclin from cultured endothelial cells
    • Harlan JM, Callahan KS (1984) Role of hydrogen peroxide in the neutrophil-mediated release of prostacyclin from cultured endothelial cells. J Clin Invest 74:442-448
    • (1984) J Clin Invest , vol.74 , pp. 442-448
    • Harlan, J.M.1    Callahan, K.S.2
  • 35
    • 0025195377 scopus 로고
    • Prostaglandin H2 may be the endothelium-derived contracting factor released by acetylcholine in the aorta of the rat
    • Kato T, Iwama Y, Okumura K, Hashimoto H, Ito T, Satake T (1990) Prostaglandin H2 may be the endothelium-derived contracting factor released by acetylcholine in the aorta of the rat. Hypertension 15:475-481
    • (1990) Hypertension , vol.15 , pp. 475-481
    • Kato, T.1    Iwama, Y.2    Okumura, K.3    Hashimoto, H.4    Ito, T.5    Satake, T.6
  • 36
    • 0035214283 scopus 로고    scopus 로고
    • Thromboxane receptor density is increased in human cardiovascular disease with evidence for inhibition at therapeutic concentrations by the at (1) receptor antagonist losartan
    • Katugampola SD, Davenport AP (2001) Thromboxane receptor density is increased in human cardiovascular disease with evidence for inhibition at therapeutic concentrations by the AT (1) receptor antagonist losartan. Br J Pharmacol 134:1385-1392
    • (2001) Br J Pharmacol , vol.134 , pp. 1385-1392
    • Katugampola, S.D.1    Davenport, A.P.2
  • 37
    • 0023182673 scopus 로고
    • Endotheliumdependent contraction to stretch in canine basilar arteries
    • Katusic Z, Shepherd JT, Vanhoutte PM (1987) Endotheliumdependent contraction to stretch in canine basilar arteries. Am J Physiol 21:H671-H673
    • (1987) Am J Physiol , vol.21
    • Katusic, Z.1    Shepherd, J.T.2    Vanhoutte, P.M.3
  • 38
    • 0023937250 scopus 로고
    • Endotheliumdependent contractions to calcium ionophore A23187, arachidonic acid and acetylcholine in canine basilar arteries
    • Katusic ZS, Shepherd JT, Vanhoutte PM (1988) Endotheliumdependent contractions to calcium ionophore A23187, arachidonic acid and acetylcholine in canine basilar arteries. Stroke 19:476-479
    • (1988) Stroke , vol.19 , pp. 476-479
    • Katusic, Z.S.1    Shepherd, J.T.2    Vanhoutte, P.M.3
  • 39
    • 0024397219 scopus 로고
    • Superoxide anion is an endothelium-derived contracting factor
    • Katusic ZS, Vanhoutte PM (1989) Superoxide anion is an endothelium-derived contracting factor. Am J Physiol 257: H33-H37
    • (1989) Am J Physiol , vol.257
    • Katusic, Z.S.1    Vanhoutte, P.M.2
  • 40
    • 0028898278 scopus 로고
    • Gender difference in endothelial dysfunction in the aorta of spontaneously hypertensive rats
    • Kauser K, Rubanyi GM (1995) Gender difference in endothelial dysfunction in the aorta of spontaneously hypertensive rats. Hypertension 25:517-523
    • (1995) Hypertension , vol.25 , pp. 517-523
    • Kauser, K.1    Rubanyi, G.M.2
  • 41
    • 33846094465 scopus 로고    scopus 로고
    • Double-label expression studies of prostacyclin synthase, thromboxane synthase and COX isoforms in normal aortic endothelium
    • Kawka DW, Ouellet M, Hétu PO, Singer II, Riendeau D (2007) Double-label expression studies of prostacyclin synthase, thromboxane synthase and COX isoforms in normal aortic endothelium. Biochim Biophys Acta 1771:45-54
    • (2007) Biochim Biophys Acta , vol.1771 , pp. 45-54
    • Kawka, D.W.1    Ouellet, M.2    Hétu, P.O.3    Singer, I.I.4    Riendeau, D.5
  • 42
    • 0030871070 scopus 로고    scopus 로고
    • Ligand binding specificities of the eight types and subtypes of the mouse prostanoid receptors expressed in Chinese hamster ovary cells
    • Kiriyama M, Ushikubi F, Kobayashi T, Hirata M, Sugimoto Y, Narumiya S (1997) Ligand binding specificities of the eight types and subtypes of the mouse prostanoid receptors expressed in Chinese hamster ovary cells. Br J Pharmacol 122:217-224
    • (1997) Br J Pharmacol , vol.122 , pp. 217-224
    • Kiriyama, M.1    Ushikubi, F.2    Kobayashi, T.3    Hirata, M.4    Sugimoto, Y.5    Narumiya, S.6
  • 43
    • 0024212486 scopus 로고
    • Ageing suppresses endothelium-dependent relaxation and generates contraction mediated by the muscarinic receptors in vascular smooth muscle of normotensiveWistar Kyoto and spontaneously hypertensive rats
    • Koga T, Takata Y, Kobayashi K, Takeshita S, Yamashita Y, Fujishima M (1988) Ageing suppresses endothelium-dependent relaxation and generates contraction mediated by the muscarinic receptors in vascular smooth muscle of normotensiveWistar Kyoto and spontaneously hypertensive rats. J Hypertens 6:S243-S245
    • (1988) J Hypertens , vol.6
    • Koga, T.1    Takata, Y.2    Kobayashi, K.3    Takeshita, S.4    Yamashita, Y.5    Fujishima, M.6
  • 44
    • 0024426160 scopus 로고
    • Age and hypertension promote endothelium-dependent contractions to acetylcholine in the aorta of the rat
    • Koga T, Takata Y, Kobayashi K, Takishita S, Yamashita Y, Fujishima M (1989) Age and hypertension promote endothelium-dependent contractions to acetylcholine in the aorta of the rat. Hypertension 14:542-548
    • (1989) Hypertension , vol.14 , pp. 542-548
    • Koga, T.1    Takata, Y.2    Kobayashi, K.3    Takishita, S.4    Yamashita, Y.5    Fujishima, M.6
  • 45
    • 67349087745 scopus 로고    scopus 로고
    • Thromboxane prostanoid receptor activation impairs endothelial nitric oxide-dependent vasorelaxations: The role of Rho kinase
    • Liu CQ, Leung FP, Wong SL, Wong WT, Lau CW, Lu L, Yao X, Yao T, Huang Y (2009) Thromboxane prostanoid receptor activation impairs endothelial nitric oxide-dependent vasorelaxations: the role of Rho kinase. Biochem Pharmacol 78:374-381
    • (2009) Biochem Pharmacol , vol.78 , pp. 374-381
    • Liu, C.Q.1    Leung, F.P.2    Wong, S.L.3    Wong, W.T.4    Lau, C.W.5    Lu, L.6    Yao, X.7    Yao, T.8    Huang, Y.9
  • 46
    • 0022545417 scopus 로고
    • Endothelium-dependent contractions to acetylcholine in the aorta of the spontaneously hypertensive rat
    • Lüscher TF, Vanhoutte PM (1986) Endothelium-dependent contractions to acetylcholine in the aorta of the spontaneously hypertensive rat. Hypertension 8:344-348
    • (1986) Hypertension , vol.8 , pp. 344-348
    • Lüscher, T.F.1    Vanhoutte, P.M.2
  • 48
    • 34548463480 scopus 로고    scopus 로고
    • Imbalance between endothelium-derived relaxing and contracting factors in mesenteric arteries from aged OLETF rats, a model of Type 2 diabetes
    • Matsumoto T, Kakami M, Noguchi E, Kobayashi T, Kamata K (2007) Imbalance between endothelium-derived relaxing and contracting factors in mesenteric arteries from aged OLETF rats, a model of Type 2 diabetes. Am J Physiol Heart Circ Physiol 293:H1480-H1490
    • (2007) Am J Physiol Heart Circ Physiol , vol.293
    • Matsumoto, T.1    Kakami, M.2    Noguchi, E.3    Kobayashi, T.4    Kamata, K.5
  • 49
    • 0033778214 scopus 로고    scopus 로고
    • Vascular bed heterogeneity in age-related endothelial dysfunction with respect to NO and eicosanoids
    • Matz RL, de Sotomayor MA, Schott C, Stoclet JC, Andriantsitohaina R (2000) Vascular bed heterogeneity in age-related endothelial dysfunction with respect to NO and eicosanoids. Br J Pharmacol 131:303-311
    • (2000) Br J Pharmacol , vol.131 , pp. 303-311
    • Matz, R.L.1    De Sotomayor, M.A.2    Schott, C.3    Stoclet, J.C.4    Andriantsitohaina, R.5
  • 50
    • 43849095463 scopus 로고    scopus 로고
    • Cardiovascular disease risk in type 2 diabetes mellitus: Insights from mechanistic studies
    • Mazzone T, Chait A, Plutzky J (2008) Cardiovascular disease risk in type 2 diabetes mellitus: insights from mechanistic studies. Lancet 371:1800-1809
    • (2008) Lancet , vol.371 , pp. 1800-1809
    • Mazzone, T.1    Chait, A.2    Plutzky, J.3
  • 52
    • 0033646835 scopus 로고    scopus 로고
    • Effects of cyclo-oxygenase inhibition on vasodilatory response to acetylcholine in patients with type 1 diabetes and nondiabetic
    • Meeking D, Browne D, Allard S, Munday J, Chowienczyk P, Shaw KM, Cummings MH (2000) Effects of cyclo-oxygenase inhibition on vasodilatory response to acetylcholine in patients with type 1 diabetes and nondiabetic. Diabetes Care 23:1-4
    • (2000) Diabetes Care , vol.23 , pp. 1-4
    • Meeking, D.1    Browne, D.2    Allard, S.3    Munday, J.4    Chowienczyk, P.5    Shaw, K.M.6    Cummings, M.H.7
  • 53
    • 0023855416 scopus 로고
    • Isolation and characterization of the complementary DNA for sheep seminal prostaglandins endoperoxide synthase (cyclooxygenase)
    • Merlie JP, Fagan D, Mudd J, Needleman P (1988) Isolation and characterization of the complementary DNA for sheep seminal prostaglandins endoperoxide synthase (cyclooxygenase). J Biol Chem 263:3550-3553
    • (1988) J Biol Chem , vol.263 , pp. 3550-3553
    • Merlie, J.P.1    Fagan, D.2    Mudd, J.3    Needleman, P.4
  • 54
    • 0022052915 scopus 로고
    • Endothelium-dependent contractions to arachidonic acid are mediated by products of cyclo-oxygenase in canine veins
    • Miller VM, Vanhoutte PM (1985) Endothelium-dependent contractions to arachidonic acid are mediated by products of cyclo-oxygenase in canine veins. Am J Physiol 248:H432-H437
    • (1985) Am J Physiol , vol.248
    • Miller, V.M.1    Vanhoutte, P.M.2
  • 55
    • 0017094798 scopus 로고
    • An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation
    • Moncada S, Gryglewski RJ, Bunting S, Vane JR (1976) An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation. Nature 263:663-665
    • (1976) Nature , vol.263 , pp. 663-665
    • Moncada, S.1    Gryglewski, R.J.2    Bunting, S.3    Vane, J.R.4
  • 56
    • 0017749182 scopus 로고
    • Differential formation of prostacyclin (PGX or PGI2) by layers of the arterial wall. An explanation for the anti-thrombotic properties of vascular endothelium
    • Moncada S, Herman AG, Higgs EA, Vane JR (1977) Differential formation of prostacyclin (PGX or PGI2) by layers of the arterial wall. An explanation for the anti-thrombotic properties of vascular endothelium. Thromb Res 11:323-344
    • (1977) Thromb Res , vol.11 , pp. 323-344
    • Moncada, S.1    Herman, A.G.2    Higgs, E.A.3    Vane, J.R.4
  • 57
    • 0018045665 scopus 로고
    • Pharmacology and endogenous roles of prostaglandin endoperoxides, thromboxane A2 and prostacyclin
    • Moncada S, Vane JR (1979) Pharmacology and endogenous roles of prostaglandin endoperoxides, thromboxane A2 and prostacyclin. Pharmacol Rev 30:293-331
    • (1979) Pharmacol Rev , vol.30 , pp. 293-331
    • Moncada, S.1    Vane, J.R.2
  • 59
    • 0025572704 scopus 로고
    • A series of prostaglandins F2-like compounds are produced in vivo in humans by a non-cyclooxygenase, free radical catalysed mechanism
    • Morrow JD, Hill KE, Burk RF, Nannour TM, Badr KF, Roberts LJ II (1990) A series of prostaglandins F2-like compounds are produced in vivo in humans by a non-cyclooxygenase, free radical catalysed mechanism. Proc Natl Acad Sci U S A 87:9383-9387
    • (1990) Proc Natl Acad Sci U S A , vol.87 , pp. 9383-9387
    • Morrow, J.D.1    Hill, K.E.2    Burk, R.F.3    Nannour, T.M.4    Badr, K.F.5    Roberts, I.I.L.J.6
  • 60
    • 59649101223 scopus 로고    scopus 로고
    • Endothelial dysfunction in mice with streptozotocin-induced type 1 diabetes is opposed by compensatory overexpression of cyclooxygenase-2 in the vasculature
    • Nacci C, Tarquinio M, De Benedictis L, Mauro A, Zigrino A, Carratù MR, Quon MJ, Montagnani M (2009) Endothelial dysfunction in mice with streptozotocin-induced type 1 diabetes is opposed by compensatory overexpression of cyclooxygenase-2 in the vasculature. Endocrinology 150:849-861
    • (2009) Endocrinology , vol.150 , pp. 849-861
    • Nacci, C.1    Tarquinio, M.2    De Benedictis, L.3    Mauro, A.4    Zigrino, A.5    Carratù, M.R.6    Quon, M.J.7    Montagnani, M.8
  • 61
    • 42649113385 scopus 로고    scopus 로고
    • Thromboxane A2: Physiology/pathophysiology, cellular signal transduction and pharmacology
    • Nakahata N (2008) Thromboxane A2: physiology/pathophysiology, cellular signal transduction and pharmacology. Pharmacol Ther 118:18-35
    • (2008) Pharmacol Ther , vol.118 , pp. 18-35
    • Nakahata, N.1
  • 62
    • 0033040983 scopus 로고    scopus 로고
    • Altered gene expression of prostacyclin synthase and prostacyclin receptor in the thoracic aorta of spontaneously hypertensive rats
    • Numaguchi Y, Harada M, Osanai H, Hayashi K, Toki Y, Okamura K, Ito T, Hayakawa T (1999) Altered gene expression of prostacyclin synthase and prostacyclin receptor in the thoracic aorta of spontaneously hypertensive rats. Cardiovasc Res 41:682-688
    • (1999) Cardiovasc Res , vol.41 , pp. 682-688
    • Numaguchi, Y.1    Harada, M.2    Osanai, H.3    Hayashi, K.4    Toki, Y.5    Okamura, K.6    Ito, T.7    Hayakawa, T.8
  • 63
    • 0026735231 scopus 로고
    • CDNA cloning and functional activity of a glucocorticoid-regulated inflammatory cyclooxygenase
    • O'Banion MK, Winn VD, Young DA (1992) cDNA cloning and functional activity of a glucocorticoid-regulated inflammatory cyclooxygenase. Proc Natl Acad Sci U S A 89:4888-4892
    • (1992) Proc Natl Acad Sci U S A , vol.89 , pp. 4888-4892
    • O'Banion, M.K.1    Winn, V.D.2    Young, D.A.3
  • 64
    • 0034068926 scopus 로고    scopus 로고
    • Differential effects of nitric oxide on the activity of prostaglandin endoperoxide H synthase-1 and -2 in vascular endothelial cells
    • Onodera M, Morita I, Mano Y, Murota S (2000) Differential effects of nitric oxide on the activity of prostaglandin endoperoxide H synthase-1 and -2 in vascular endothelial cells. Prostaglandins Leukot Essent Fatty Acids 62:161-167
    • (2000) Prostaglandins Leukot Essent Fatty Acids , vol.62 , pp. 161-167
    • Onodera, M.1    Morita, I.2    Mano, Y.3    Murota, S.4
  • 65
    • 0023187143 scopus 로고
    • Comparative pharmacology of endothelium-derived relaxing factor, nitric oxide and prostacyclin in platelets
    • Radomski MW, Palmer RMJ, Moncada S (1987) Comparative pharmacology of endothelium-derived relaxing factor, nitric oxide and prostacyclin in platelets. Br J Pharmacol 92:181-187
    • (1987) Br J Pharmacol , vol.92 , pp. 181-187
    • Radomski, M.W.1    Palmer, R.M.J.2    Moncada, S.3
  • 66
    • 0023446425 scopus 로고
    • The antiaggregating properties of vascular endothelium: Interactions between prostacyclin and nitric oxide
    • Radomski MW, Palmer RMJ, Moncada S (1987) The antiaggregating properties of vascular endothelium: interactions between prostacyclin and nitric oxide. Br J Pharmacol 92:639-646
    • (1987) Br J Pharmacol , vol.92 , pp. 639-646
    • Radomski, M.W.1    Palmer, R.M.J.2    Moncada, S.3
  • 67
    • 0029947695 scopus 로고    scopus 로고
    • Role of prostaglandins in acetylcholine-induced contraction of aorta from spontaneously hypertensive and Wistar-Kyoto rats
    • Rapoport RM, Williams SP (1996) Role of prostaglandins in acetylcholine-induced contraction of aorta from spontaneously hypertensive and Wistar-Kyoto rats. Hypertension 28:64-75
    • (1996) Hypertension , vol.28 , pp. 64-75
    • Rapoport, R.M.1    Williams, S.P.2
  • 68
    • 77549083579 scopus 로고    scopus 로고
    • Dual COXIB/TP antagonists: A possible new twist in NASID pharmacology and cardiovascular risk
    • Rovati GE, Sala, A, Capra V, Dahlen SE, Folco G. (2010) Dual COXIB/TP antagonists: a possible new twist in NASID pharmacology and cardiovascular risk. Trends Pharmacol Sci 31:102-107
    • (2010) Trends Pharmacol Sci , vol.31 , pp. 102-107
    • Rovati, G.E.1    Sala, A.2    Capra, V.3    Dahlen, S.E.4    Folco, G.5
  • 69
    • 0022456638 scopus 로고
    • Superoxide anions and hyperoxia inactivate endothelium-derived relaxing factor
    • Rubanyi GM, Vanhoutte PM (1986) Superoxide anions and hyperoxia inactivate endothelium-derived relaxing factor. Am J Physiol 250:H222-H227
    • (1986) Am J Physiol , vol.250
    • Rubanyi, G.M.1    Vanhoutte, P.M.2
  • 70
    • 33847616500 scopus 로고    scopus 로고
    • The calcium ionophore A23187 induces endotheliumdependent contractions in femoral arteries from rats with streptozotocin-induced diabetes
    • Shi Y, Feletou M, Ku DD, Man RYK, Vanhoutte PM (2007) The calcium ionophore A23187 induces endotheliumdependent contractions in femoral arteries from rats with streptozotocin-induced diabetes. Br J Pharmacol 150:624-632
    • (2007) Br J Pharmacol , vol.150 , pp. 624-632
    • Shi, Y.1    Feletou, M.2    Ku, D.D.3    Man, R.Y.K.4    Vanhoutte, P.M.5
  • 71
    • 38749089857 scopus 로고    scopus 로고
    • Two isoforms of cyclooxygenase contribute to augmented endothelium-dependent contractions in femoral arteries of 1-year-old rats
    • Shi Y, Man RY, Vanhoutte PM (2008) Two isoforms of cyclooxygenase contribute to augmented endothelium-dependent contractions in femoral arteries of 1-year-old rats. Acta Pharmacol Sin 29:185-192
    • (2008) Acta Pharmacol Sin , vol.29 , pp. 185-192
    • Shi, Y.1    Man, R.Y.2    Vanhoutte, P.M.3
  • 73
    • 0025728865 scopus 로고
    • Prostaglandin endoperoxide synthase: Structure and catalysis
    • Smith WL, Marnett LJ (1991) Prostaglandin endoperoxide synthase: structure and catalysis. Biochem Biophys Acta 1083:1-17
    • (1991) Biochem Biophys Acta , vol.1083 , pp. 1-17
    • Smith, W.L.1    Marnett, L.J.2
  • 74
    • 0026477109 scopus 로고
    • 2+ release from vascular smooth muscle sarcoplasmic reticulum
    • 2+ release from vascular smooth muscle sarcoplasmic reticulum. Am J Physiol 262:H114-H116
    • (1992) Am J Physiol , vol.262
    • Suzuki, Y.J.1    Ford, G.D.2
  • 75
    • 0027393348 scopus 로고
    • Role of endothelium in endothelin-evoked contractions in the rat aorta
    • Taddei S, Vanhoutte PM (1993) Role of endothelium in endothelin-evoked contractions in the rat aorta. Hypertension 21:9-15
    • (1993) Hypertension , vol.21 , pp. 9-15
    • Taddei, S.1    Vanhoutte, P.M.2
  • 76
    • 0030641082 scopus 로고    scopus 로고
    • Cyclooxygenase inhibition restores nitric oxide activity in essential hypertension
    • Taddei S, Virdis A, Ghiadoni L, Magagna A, Salvetti A (1997) Cyclooxygenase inhibition restores nitric oxide activity in essential hypertension. Hypertension 29:274-279
    • (1997) Hypertension , vol.29 , pp. 274-279
    • Taddei, S.1    Virdis, A.2    Ghiadoni, L.3    Magagna, A.4    Salvetti, A.5
  • 79
    • 33644684847 scopus 로고    scopus 로고
    • Endothelium-dependent contractions occur in the aorta of wild-type and COX2-/-knockout but not COX1-/-knockout mice
    • Tang EH, Ku DD, Tipoe GL, Félétou M, Man RY, Vanhoutte PM (2005) Endothelium-dependent contractions occur in the aorta of wild-type and COX2-/-knockout but not COX1-/-knockout mice. J Cardiovasc Pharmacol 46:761-765
    • (2005) J Cardiovasc Pharmacol , vol.46 , pp. 761-765
    • Tang, E.H.1    Ku, D.D.2    Tipoe, G.L.3    Félétou, M.4    Man, R.Y.5    Vanhoutte, P.M.6
  • 80
    • 34247608691 scopus 로고    scopus 로고
    • Calcium and reactive oxygen species increase in endothelial cells in response to releasers of endothelium-derived contracting factor
    • Tang EH, Leung FP, Huang Y, Félétou M, So KF, Man RY, Vanhoutte PM (2007) Calcium and reactive oxygen species increase in endothelial cells in response to releasers of endothelium-derived contracting factor. Br J Pharmacol 151:15-23
    • (2007) Br J Pharmacol , vol.151 , pp. 15-23
    • Tang, E.H.1    Leung, F.P.2    Huang, Y.3    Félétou, M.4    So, K.F.5    Man, R.Y.6    Vanhoutte, P.M.7
  • 81
    • 40149085142 scopus 로고    scopus 로고
    • Gene expression changes of prostanoid synthases in endothelial cells and prostanoid receptors in vascular smooth muscle cells caused by aging and hypertension
    • Tang EH, Vanhoutte PM (2008) Gene expression changes of prostanoid synthases in endothelial cells and prostanoid receptors in vascular smooth muscle cells caused by aging and hypertension. Physiol Genomics 32:409-418
    • (2008) Physiol Genomics , vol.32 , pp. 409-418
    • Tang, E.H.1    Vanhoutte, P.M.2
  • 82
    • 0028910553 scopus 로고
    • 15-Hydroxyeicosatetraenoic acid and diabetic endothelial dysfunction in rabbit aorta
    • Tesfamariam B, Brown ML, Cohen RA (1995) 15-Hydroxyeicosatetraenoic acid and diabetic endothelial dysfunction in rabbit aorta. J Cardiovasc Pharmacol 25:748-755
    • (1995) J Cardiovasc Pharmacol , vol.25 , pp. 748-755
    • Tesfamariam, B.1    Brown, M.L.2    Cohen, R.A.3
  • 83
    • 0029790770 scopus 로고    scopus 로고
    • Identification of vascular endothelial genes differentially responsive to fluid mechanical stimuli: Cyclooxygenase-2, manganese superoxide dismutase, and endothelial cell nitric oxide synthase are selectively up-regulated by steady laminar shear stress
    • Topper JN, Cai J, Falb D, Gimbrone MA Jr (1996) Identification of vascular endothelial genes differentially responsive to fluid mechanical stimuli: cyclooxygenase-2, manganese superoxide dismutase, and endothelial cell nitric oxide synthase are selectively up-regulated by steady laminar shear stress. Proc Natl Acad Sci U S A 93:10417-10422
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 10417-10422
    • Topper, J.N.1    Cai, J.2    Falb, D.3    Gimbrone Jr., M.A.4
  • 85
    • 1542289579 scopus 로고    scopus 로고
    • The mechanism of oxidative stress stabilization of the thromboxane receptor in COS-7 cells
    • Valentin F, Field MC, Tippins JR (2004) The mechanism of oxidative stress stabilization of the thromboxane receptor in COS-7 cells. J Biol Chem 279:8316-8324
    • (2004) J Biol Chem , vol.279 , pp. 8316-8324
    • Valentin, F.1    Field, M.C.2    Tippins, J.R.3
  • 86
    • 0025968167 scopus 로고
    • 15-lipoxygenase metabolites of arachidonic acid evoke contractions and relaxations in isolated canine arteries: Role of thromboxane receptors, endothelial cells and cyclooxygenase
    • Van Diest MJ, Verbeuren TJ, Herman AG (1991) 15-lipoxygenase metabolites of arachidonic acid evoke contractions and relaxations in isolated canine arteries: role of thromboxane receptors, endothelial cells and cyclooxygenase. J Pharmacol Exp Ther 256:194-203
    • (1991) J Pharmacol Exp Ther , vol.256 , pp. 194-203
    • Van Diest, M.J.1    Verbeuren, T.J.2    Herman, A.G.3
  • 88
    • 14844320534 scopus 로고    scopus 로고
    • Endotheliumdependent contractions in hypertension
    • Vanhoutte PM, Félétou M, Taddei S (2005) Endotheliumdependent contractions in hypertension. Br J Pharmacol 144:449-458
    • (2005) Br J Pharmacol , vol.144 , pp. 449-458
    • Vanhoutte, P.M.1    Félétou, M.2    Taddei, S.3
  • 89
    • 33645831993 scopus 로고    scopus 로고
    • Terutroban and endothelial TP receptors in atherogenesis
    • Verbeuren TJ (2006) Terutroban and endothelial TP receptors in atherogenesis. Med Sci (Paris) 22:437-443
    • (2006) Med Sci (Paris) , vol.22 , pp. 437-443
    • Verbeuren, T.J.1
  • 93
    • 67650544152 scopus 로고    scopus 로고
    • Activation-dependent stabilization of the human thromboxane receptor: Role of reactive oxygen species
    • Wilson SJ, Cavanagh CC, Lesher AM, Frey AJ, Russell SE, Smyth EM (2009) Activation-dependent stabilization of the human thromboxane receptor: role of reactive oxygen species. J Lipid Res 50:1047-1056
    • (2009) J Lipid Res , vol.50 , pp. 1047-1056
    • Wilson, S.J.1    Cavanagh, C.C.2    Lesher, A.M.3    Frey, A.J.4    Russell, S.E.5    Smyth, E.M.6
  • 94
    • 0030026928 scopus 로고    scopus 로고
    • Focus on prostacyclin and its novel mimetics
    • Wise H, Jones RL (1996) Focus on prostacyclin and its novel mimetics. Trends Pharmacol Sci 17:17-21
    • (1996) Trends Pharmacol Sci , vol.17 , pp. 17-21
    • Wise, H.1    Jones, R.L.2
  • 95
    • 77949760342 scopus 로고    scopus 로고
    • Calciumindependent phospholipase A2 plays a key role in the endothelium-dependent contractions to acetylcholine in the aorta of SHR
    • in press
    • Wong MS, Man RY, Vanhoutte PM. (2010) Calciumindependent phospholipase A2 plays a key role in the endothelium-dependent contractions to acetylcholine in the aorta of SHR. Am J Physiol Heart Circ Physiol (in press)
    • (2010) Am J Physiol Heart Circ Physiol
    • Wong, M.S.1    Man, R.Y.2    Vanhoutte, P.M.3
  • 96
    • 84865105357 scopus 로고    scopus 로고
    • Endothelium-dependent contractions in hamster aorta: The essential role of COX-2 and prostaglandin-2α
    • Wong SL, Leung FP, Lau CW, Vanhoutte P, Huang Y (2008) Endothelium-dependent contractions in hamster aorta: the essential role of COX-2 and prostaglandin-2α. Basic Clin Pharmacol Toxicol 102(suppl 1):15-15
    • (2008) Basic Clin Pharmacol Toxicol , vol.102 , Issue.SUPPL. 1 , pp. 15-15
    • Wong, S.L.1    Leung, F.P.2    Lau, C.W.3    Vanhoutte, P.4    Huang, Y.5
  • 97
    • 59849107087 scopus 로고    scopus 로고
    • Cyclooxygenase-2-derived prostaglandin F2alpha mediates endothelium-dependent contractions in the aortae of hamsters with increased impact during aging
    • Wong SL, Leung FP, Lau CW, Au CL, Yung LM, Yao X, Chen ZY, Vanhoutte PM, Gollasch M, Huang Y (2009) Cyclooxygenase-2-derived prostaglandin F2alpha mediates endothelium-dependent contractions in the aortae of hamsters with increased impact during aging. Circ Res 104:228-235
    • (2009) Circ Res , vol.104 , pp. 228-235
    • Wong, S.L.1    Leung, F.P.2    Lau, C.W.3    Au, C.L.4    Yung, L.M.5    Yao, X.6    Chen, Z.Y.7    Vanhoutte, P.M.8    Gollasch, M.9    Huang, Y.10
  • 98
    • 20444401593 scopus 로고    scopus 로고
    • The contribution of nitric oxide and vasodilatory prostanoids to bradykinin-mediated vasodilation in Type 1 diabetes
    • Wotherspoon F, Browne DL, Meeking DR, Allard SE, Munday LJ, Shaw KM, Cummings MH (2005) The contribution of nitric oxide and vasodilatory prostanoids to bradykinin-mediated vasodilation in Type 1 diabetes. Diabet Med 22:697-702
    • (2005) Diabet Med , vol.22 , pp. 697-702
    • Wotherspoon, F.1    Browne, D.L.2    Meeking, D.R.3    Allard, S.E.4    Munday, L.J.5    Shaw, K.M.6    Cummings, M.H.7
  • 99
    • 47249130765 scopus 로고    scopus 로고
    • Aldosterone induces endothelial dysfunction in resistance arteries from normotensive and hypertensive rats by increasing thromboxane A2 and prostacyclin
    • Xavier FE, Aras-López R, Arroyo-Villa I, Campo LD, Salaices M, Rossoni LV, Ferrer M, Balfagón G (2008) Aldosterone induces endothelial dysfunction in resistance arteries from normotensive and hypertensive rats by increasing thromboxane A2 and prostacyclin. Br J Pharmacol 154:1225-1235
    • (2008) Br J Pharmacol , vol.154 , pp. 1225-1235
    • Xavier, F.E.1    Aras-López, R.2    Arroyo-Villa, I.3    Campo, L.D.4    Salaices, M.5    Rossoni, L.V.6    Ferrer, M.7    Balfagón, G.8
  • 100
    • 0036264483 scopus 로고    scopus 로고
    • Oxygen-derived free radicals mediate endothelium-dependent contractions to acetylcholine in aortas from spontaneously hypertensive rats
    • Yang D, Félétou M, Boulanger CM, Wu HF, Levens N, Zhang JN, Vanhoutte PM (2002) Oxygen-derived free radicals mediate endothelium-dependent contractions to acetylcholine in aortas from spontaneously hypertensive rats. Br J Pharmacol 136:104-110
    • (2002) Br J Pharmacol , vol.136 , pp. 104-110
    • Yang, D.1    Félétou, M.2    Boulanger, C.M.3    Wu, H.F.4    Levens, N.5    Zhang, J.N.6    Vanhoutte, P.M.7
  • 101
    • 0037219457 scopus 로고    scopus 로고
    • A diffusible substance(s) mediates endothelium-dependent contractions in the aorta of SHR
    • Yang D, Félétou M, Levens N, Zhang JN, Vanhoutte PM (2003) A diffusible substance(s) mediates endothelium-dependent contractions in the aorta of SHR. Hypertension 41:143-148
    • (2003) Hypertension , vol.41 , pp. 143-148
    • Yang, D.1    Félétou, M.2    Levens, N.3    Zhang, J.N.4    Vanhoutte, P.M.5
  • 102
    • 0037219687 scopus 로고    scopus 로고
    • Specific potentiation of endothelium-dependent contractions in SHR by tetrahydrobiopterin
    • Yang D, Levens N, Zhang JN, Vanhoutte PM, Félétou M (2003) Specific potentiation of endothelium-dependent contractions in SHR by tetrahydrobiopterin. Hypertension 41:136-142
    • (2003) Hypertension , vol.41 , pp. 136-142
    • Yang, D.1    Levens, N.2    Zhang, J.N.3    Vanhoutte, P.M.4    Félétou, M.5
  • 103
    • 2942572772 scopus 로고    scopus 로고
    • Endothelium-dependent contractions to acetylcholine, ATP and the calcium ionophore A 23187 in aortas from spontaneously hypertensive and normotensive rats
    • Yang D, Gluais P, Zhang JN, Vanhoutte PM, Félétou M (2004) Endothelium-dependent contractions to acetylcholine, ATP and the calcium ionophore A 23187 in aortas from spontaneously hypertensive and normotensive rats. Fundam Clin Pharmacol 18:321-326
    • (2004) Fundam Clin Pharmacol , vol.18 , pp. 321-326
    • Yang, D.1    Gluais, P.2    Zhang, J.N.3    Vanhoutte, P.M.4    Félétou, M.5
  • 104
    • 0023915232 scopus 로고
    • Primary structure of sheep prostaglandin endoperoxide synthase deduced from cDNA sequence
    • Yokohama C, Takai T, Tanabe T (1988) Primary structure of sheep prostaglandin endoperoxide synthase deduced from cDNA sequence. FEBS Lett 231:347-351
    • (1988) FEBS Lett , vol.231 , pp. 347-351
    • Yokohama, C.1    Takai, T.2    Tanabe, T.3
  • 105
    • 0031966133 scopus 로고    scopus 로고
    • Augmented endothelium-dependent contraction to angiotensin II in the SHR aorta: Role of an inducible cyclooxygenase metabolite
    • Zerrouk A, Auguet M, Chabrier PE (1998) Augmented endothelium-dependent contraction to angiotensin II in the SHR aorta: role of an inducible cyclooxygenase metabolite. J Cardiovasc Pharmacol 31:525-533
    • (1998) J Cardiovasc Pharmacol , vol.31 , pp. 525-533
    • Zerrouk, A.1    Auguet, M.2    Chabrier, P.E.3
  • 106
    • 33745382953 scopus 로고    scopus 로고
    • Increased expression of cyclooxygenase-2 mediates enhanced contraction to endothelin ETA receptor stimulation in endothelial nitric oxide synthase knockout mice
    • Zhou Y, Mitra S, Varadharaj S, Parinandi N, Zweier JL, Flavahan NA (2006) Increased expression of cyclooxygenase-2 mediates enhanced contraction to endothelin ETA receptor stimulation in endothelial nitric oxide synthase knockout mice. Circ Res 98:1439-1445
    • (2006) Circ Res , vol.98 , pp. 1439-1445
    • Zhou, Y.1    Mitra, S.2    Varadharaj, S.3    Parinandi, N.4    Zweier, J.L.5    Flavahan, N.A.6
  • 107
    • 0036098197 scopus 로고    scopus 로고
    • High glucose via peroxynitrite causes tyrosine nitration and inactivation of prostacyclin synthase that is associated with thromboxane/prostaglandin H(2) receptormediated apoptosis and adhesion molecule expression in cultured human aortic endothelial cells
    • Zou MH, Shi C, Cohen RA (2002) High glucose via peroxynitrite causes tyrosine nitration and inactivation of prostacyclin synthase that is associated with thromboxane/prostaglandin H(2) receptormediated apoptosis and adhesion molecule expression in cultured human aortic endothelial cells. Diabetes 51:198-203
    • (2002) Diabetes , vol.51 , pp. 198-203
    • Zou, M.H.1    Shi, C.2    Cohen, R.A.3


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