-
1
-
-
0034093126
-
Requirement for BMP and FGF signaling during cardiogenic induction in non-precardiac mesoderm is specific, transient, and cooperative
-
Barron M, Gao M, and Lough J. Requirement for BMP and FGF signaling during cardiogenic induction in non-precardiac mesoderm is specific, transient, and cooperative. Dev Dyn 218: 383-393, 2000.
-
(2000)
Dev Dyn
, vol.218
, pp. 383-393
-
-
Barron, M.1
Gao, M.2
Lough, J.3
-
2
-
-
0025998840
-
Phosphopeptide mapping and phosphoamino acid analysis by two-dimensional separation on thin-layer cellulose plates
-
Boyle WJ, van der Geer P, and Hunter T. Phosphopeptide mapping and phosphoamino acid analysis by two-dimensional separation on thin-layer cellulose plates. Methods Enzymol 201: 110-149, 1991.
-
(1991)
Methods Enzymol
, vol.201
, pp. 110-149
-
-
Boyle, W.J.1
Van der Geer, P.2
Hunter, T.3
-
3
-
-
0030922980
-
Characterization of functional domains within Smad4/DPC 4
-
De Caestecker MP, Hemmati P, Larisch-Bloch S, Ajmera R, Roberts AB, and Lechleider RJ. Characterization of functional domains within Smad4/DPC4. J Biol Chem 272: 13690-13696, 1997.
-
(1997)
J Biol Chem
, vol.272
, pp. 13690-13696
-
-
De Caestecker, M.P.1
Hemmati, P.2
Larisch-Bloch, S.3
Ajmera, R.4
Roberts, A.B.5
Lechleider, R.J.6
-
4
-
-
2642605344
-
Smad2 transduces common signals from receptor serine-threonine and tyrosine kinases
-
De Caestecker MP, Parks WT, Frank CJ, Castagnino P, Bottaro DP, Roberts AB, and Lechleider RJ. Smad2 transduces common signals from receptor serine-threonine and tyrosine kinases. Genes Dev 12: 1587-1592, 1998.
-
(1998)
Genes Dev
, vol.12
, pp. 1587-1592
-
-
De Caestecker, M.P.1
Parks, W.T.2
Frank, C.J.3
Castagnino, P.4
Bottaro, D.P.5
Roberts, A.B.6
Lechleider, R.J.7
-
5
-
-
0034695590
-
The Smad4 activation domain (SAD) is a proline-rich, p300-dependent transcriptional activation domain
-
De Caestecker MP, Yahata T, Wang D, Parks WT, Huang S, Hill SH, Shioda T, Roberts AB, and Lechleider RJ. The Smad4 activation domain (SAD) is a proline-rich, p300-dependent transcriptional activation domain. J Biol Chem 275: 2115-2122, 2000.
-
(2000)
J Biol Chem
, vol.275
, pp. 2115-2122
-
-
De Caestecker, M.P.1
Yahata, T.2
Wang, D.3
Parks, W.T.4
Huang, S.5
Hill, S.H.6
Shioda, T.7
Roberts, A.B.8
Lechleider, R.J.9
-
6
-
-
0032101178
-
Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene
-
Dennler S, Itoh S, Vivien D, ten Dijke P, Huet S, and Gauthier JM. Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene. EMBO J 17: 3091-3100, 1998.
-
(1998)
EMBO J
, vol.17
, pp. 3091-3100
-
-
Dennler, S.1
Itoh, S.2
Vivien, D.3
Ten Dijke, P.4
Huet, S.5
Gauthier, J.M.6
-
7
-
-
0033601179
-
Interdependent SMAD JNK signaling in transforming growth factor-beta-mediated transcription
-
Engel ME, McDonnel MA, Law BK, and Moses HL. Interdependent SMAD and JNK signaling in transforming growth factor-beta-mediated transcription. JBiol Chem 274: 37413-37420, 1999.
-
(1999)
JBiol Chem
, vol.274
, pp. 37413-37420
-
-
Engel, M.E.1
McDonnel, M.A.2
Law, B.K.3
Moses, H.L.4
-
8
-
-
14444279192
-
Identification of a novel inhibitor of mitogen-activated protein kinase kinase
-
Favata MF, Horiuchi KY, Manos EJ, Daulerio AJ, Stradley DA, Feeser WS, Van Dyk DE, Pitt WJ, Earl RA, Hobbs F, Copeland RA, Magolda RL, Scherle PA, and Trzaskos JM. Identification of a novel inhibitor of mitogen-activated protein kinase kinase. J Biol Chem 273: 18623-18632, 1998.
-
(1998)
J Biol Chem
, vol.273
, pp. 18623-18632
-
-
Favata, M.F.1
Horiuchi, K.Y.2
Manos, E.J.3
Daulerio, A.J.4
Stradley, D.A.5
Feeser, W.S.6
Van Dyk, D.E.7
Pitt, W.J.8
Earl, R.A.9
Hobbs, F.10
Copeland, R.A.11
Magolda, R.L.12
Scherle, P.A.13
Trzaskos, J.M.14
-
9
-
-
0027952883
-
Induction of chondrogenesis: Requirement for synergistic interaction of basic fibroblast growth factor and transforming growth factor-beta
-
Frenz DA, Liu W, Williams JD, Hatcher V, Galinovic-Schwartz V, Flanders KC, and Van De Water TR. Induction of chondrogenesis: requirement for synergistic interaction of basic fibroblast growth factor and transforming growth factor-beta. Development 120: 415-424, 1994.
-
(1994)
Development
, vol.120
, pp. 415-424
-
-
Frenz, D.A.1
Liu, W.2
Williams, J.D.3
Hatcher, V.4
Galinovic-Schwartz, V.5
Flanders, K.C.6
Van De Water, T.R.7
-
10
-
-
0030593038
-
DPC 4, a candidate tumor suppressor gene at human chromosome 18q21.1
-
Hahn SA, Schutte M, Hoque ATMS, Moskaluk CA, da Costa LT, Rozenblum E, Weinstein CL, Fischer A, Yeo CJ, Hruban RH, and Kern SE. DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1. Science 271: 350-353, 1996.
-
(1996)
Science
, vol.271
, pp. 350-353
-
-
Hahn, S.A.1
Schutte, M.2
Hoque, A.T.M.S.3
Moskaluk, C.A.4
Da Costa, L.T.5
Rozenblum, E.6
Weinstein, C.L.7
Fischer, A.8
Yeo, C.J.9
Hruban, R.H.10
Kern, S.E.11
-
11
-
-
0030825516
-
Mutations increasing autoinhibition inactivate tumour suppressors Smad 2 and Smad4
-
Hata A, Lo RS, Wotton D, Lagna G, and Massagué J. Mutations increasing autoinhibition inactivate tumour suppressors Smad2 and Smad4. Nature 388: 82-87, 1997.
-
(1997)
Nature
, vol.388
, pp. 82-87
-
-
Hata, A.1
Lo, R.S.2
Wotton, D.3
Lagna, G.4
Massagué, J.5
-
12
-
-
0031438047
-
TGF-beta signalling from cell membrane to nucleus through SMAD proteins
-
Heldin CH, Miyazono K, and ten Dijke P. TGF-beta signalling from cell membrane to nucleus through SMAD proteins. Nature 390: 465-471, 1997.
-
(1997)
Nature
, vol.390
, pp. 465-471
-
-
Heldin, C.H.1
Miyazono, K.2
Ten Dijke, P.3
-
13
-
-
0030773834
-
Opposing BMP EGF signalling pathways converge on the TGF-beta family mediator Smadl
-
Kretzschmar M, Doody J, and Massagué J. Opposing BMP and EGF signalling pathways converge on the TGF-beta family mediator Smadl. Nature 389: 618-622, 1997.
-
(1997)
Nature
, vol.389
, pp. 618-622
-
-
Kretzschmar, M.1
Doody, J.2
Massagué, J.3
-
14
-
-
0033106484
-
A mechanism of repression of TGFbeta/Smad signaling by oncogenic Ras
-
Kretzschmar M, Doody J, Timokhina I, and Massagué J. A mechanism of repression of TGFbeta/Smad signaling by oncogenic Ras. Genes Dev 13: 804-816, 1999.
-
(1999)
Genes Dev
, vol.13
, pp. 804-816
-
-
Kretzschmar, M.1
Doody, J.2
Timokhina, I.3
Massagué, J.4
-
15
-
-
0030300115
-
MADR 2 is a substrate of the TGFbeta receptor and its phosphorylation is required for nuclear accumulation and signaling
-
Macias-Silva M, Abdollah S, Hoodless PA, Pirone R, Attisano L, and Wrana JL. MADR2 is a substrate of the TGFbeta receptor and its phosphorylation is required for nuclear accumulation and signaling. Cell 87: 1215-1224, 1996.
-
(1996)
Cell
, vol.87
, pp. 1215-1224
-
-
Macias-Silva, M.1
Abdollah, S.2
Hoodless, P.A.3
Pirone, R.4
Attisano, L.5
Wrana, J.L.6
-
16
-
-
0034023127
-
Role of Ras and Mapks in TGFβ signaling
-
Mulder KM. Role of Ras and Mapks in TGFβ signaling. Cytokine Growth Factor Rev 11: 23-35, 2000.
-
(2000)
Cytokine Growth Factor Rev
, vol.11
, pp. 23-35
-
-
Mulder, K.M.1
-
17
-
-
0030768644
-
TGF-beta receptor-mediated signalling through Smad 2, Smad3 and Smad4
-
Nakao A, Imamura T, Souchelnytskyi S, Kawabata M, Ishisaki A, Oeda E, Tamaki K, Hanai J, Heldin CH, Miyazono K, and ten Dijke P. TGF-beta receptor-mediated signalling through Smad2, Smad3 and Smad4. EMBO J 16: 5353-5362, 1997.
-
(1997)
EMBO J
, vol.16
, pp. 5353-5362
-
-
Nakao, A.1
Imamura, T.2
Souchelnytskyi, S.3
Kawabata, M.4
Ishisaki, A.5
Oeda, E.6
Tamaki, K.7
Hanai, J.8
Heldin, C.H.9
Miyazono, K.10
Ten Dijke, P.11
-
18
-
-
0034460336
-
Transforming growth factor beta-independent shuttling of Smad 4 between the cytoplasm and nucleus
-
Pierreux CE, Nicolás FJ, and Hill CS. Transforming growth factor beta-independent shuttling of Smad4 between the cytoplasm and nucleus. Mol Cell Biol 20: 9041-9054, 2000.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 9041-9054
-
-
Pierreux, C.E.1
Nicolás, F.J.2
Hill, C.S.3
-
19
-
-
0035028136
-
TGF-β 2, LIF and FGF2 cooperate to induce nephrogenesis
-
Plisov SY, Yoshino K, Dove LF, Higinbotham KG, Rubin JS, and Perantoni AO. TGF-β2, LIF and FGF2 cooperate to induce nephrogenesis. Development 128: 1045-1057, 2001.
-
(2001)
Development
, vol.128
, pp. 1045-1057
-
-
Plisov, S.Y.1
Yoshino, K.2
Dove, L.F.3
Higinbotham, K.G.4
Rubin, J.S.5
Perantoni, A.O.6
-
20
-
-
0033573092
-
Crystal structure of a transcriptionally active Smad 4 fragment
-
Qin B, Lam SS, and Lin K. Crystal structure of a transcriptionally active Smad4 fragment. Structure Fold Des 7: 1493-1503, 1999.
-
(1999)
Structure Fold Des
, vol.7
, pp. 1493-1503
-
-
Qin, B.1
Lam, S.S.2
Lin, K.3
-
21
-
-
0035800838
-
Oncogenic ras represses transforming growth factor-beta/Smad signaling by degrading tumor suppressor Smad 4
-
Saha D, Datta PK, and Beauchamp RD. Oncogenic ras represses transforming growth factor-beta/Smad signaling by degrading tumor suppressor Smad4. J Biol Chem 276: 29531-29537, 2001.
-
(2001)
J Biol Chem
, vol.276
, pp. 29531-29537
-
-
Saha, D.1
Datta, P.K.2
Beauchamp, R.D.3
-
22
-
-
9344223357
-
Abrogation of the Rb/p16 tumor-suppressive pathway in virtually all pancreatic carcinomas
-
Schutte M, Hruban RH, Hedrick L, Cho KR, Molnar Nadasdy G, Weinstein CL, Bova GS, Isaacs WB, Cairns P, Nawroz H, Sidransky D, Casero RA, Meltzer PS, Hahn SA, and Kern SA. Abrogation of the Rb/p16 tumor-suppressive pathway in virtually all pancreatic carcinomas. Cancer Res 56: 2527-2530, 1996.
-
(1996)
Cancer Res
, vol.56
, pp. 2527-2530
-
-
Schutte, M.1
Hruban, R.H.2
Hedrick, L.3
Cho, K.R.4
Molnar Nadasdy, G.5
Weinstein, C.L.6
Bova, G.S.7
Isaacs, W.B.8
Cairns, P.9
Nawroz, H.10
Sidransky, D.11
Casero, R.A.12
Meltzer, P.S.13
Hahn, S.A.14
Kern, S.A.15
-
23
-
-
0032483544
-
Crystal structure of a Smad MH1 domain bound to DNA: Insights on DNA binding in TGF-beta signaling
-
Shi Y, Jayaraman L, Yang H, Massagué J, and Pavletich NP. Crystal structure of a Smad MH1 domain bound to DNA: insights on DNA binding in TGF-beta signaling. Cell 94: 585-594, 1998.
-
(1998)
Cell
, vol.94
, pp. 585-594
-
-
Shi, Y.1
Jayaraman, L.2
Yang, H.3
Massagué, J.4
Pavletich, N.P.5
-
24
-
-
0030862345
-
Synergistic interactions between bFGF and a TGF-β family member may mediate myogenic signals from the neural tube
-
Stern HM, Lin-Jones J, and Hauschka SD. Synergistic interactions between bFGF and a TGF-β family member may mediate myogenic signals from the neural tube. Development 124:3511-3523, 1997.
-
(1997)
Development
, vol.124
, pp. 3511-3523
-
-
Stern, H.M.1
Lin-Jones, J.2
Hauschka, S.D.3
-
25
-
-
0030963943
-
DPC4 (SMAD4) mediates transforming growth factor-betal (TGF-beta1) induced growth inhibition and transcriptional response in breast tumour cells
-
De Winter JP, Roelen BAJ, ten Dijke P, van der Burg B, and van den Eijnden-van Raaij AJM. DPC4 (SMAD4) mediates transforming growth factor-betal (TGF-beta1) induced growth inhibition and transcriptional response in breast tumour cells. Oncogene 14: 1891-1899, 1997.
-
(1997)
Oncogene
, vol.14
, pp. 1891-1899
-
-
De Winter, J.P.1
Roelen, B.A.J.2
Ten Dijke, P.3
Van der Burg, B.4
Van den Eijnden-van Raaij, A.J.M.5
-
26
-
-
0032014216
-
Human Smad3 and Smad4 are sequence-specific transcription activators
-
Zawel L, Le Dai J, Buckhaults P, Zhou S, Kinzler KW, Vogelstein B, and Kern SE. Human Smad3 and Smad4 are sequence-specific transcription activators. Mol Cell 1: 611-617, 1998.
-
(1998)
Mol Cell
, vol.1
, pp. 611-617
-
-
Zawel, L.1
Le Dai, J.2
Buckhaults, P.3
Zhou, S.4
Kinzler, K.W.5
Vogelstein, B.6
Kern, S.E.7
-
27
-
-
0031128153
-
The tumor suppressor Smad4/DPC 4 as a central mediator of Smad function
-
Zhang Y, Musci T, and Derynck R. The tumor suppressor Smad4/DPC 4 as a central mediator of Smad function. Curr Biol 7: 270-276, 1997.
-
(1997)
Curr Biol
, vol.7
, pp. 270-276
-
-
Zhang, Y.1
Musci, T.2
Derynck, R.3
|