Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21

Nature Immunology

Volumn 11, Issue 2, 2010, Pages 141-147

  Sheedy, Frederick J ^a   Palsson Mcdermott, Eva ^b   Hennessy, Elizabeth J ^c   Martin, Cara ^b,c   O'Leary, John J ^b,c   Ruan, Qingguo ^d   Johnson, Derek S ^d   Chen, Youhai ^d   O'Neill, Luke A J ^a  

^a TRINITY COLLEGE DUBLIN   (Ireland)

^b Pathology Research Laboratory   (Ireland)

^c TRINITY COLLEGE DUBLIN   (Ireland)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MESSENGER RNA; MICRORNA; MIR 21; MYELOID DIFFERENTIATION FACTOR 88; PROTEIN PDCD4; TOLL LIKE RECEPTOR 4; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG; APOPTOSIS REGULATORY PROTEIN; INTERLEUKIN 1 RECEPTOR; MEMBRANE PROTEIN; MIRN21 MICRORNA, HUMAN; PDCD4 PROTEIN, HUMAN; RNA BINDING PROTEIN; TIRAP PROTEIN, HUMAN;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOBLOTTING; IMMUNOPRECIPITATION; MOUSE; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; REGULATORY MECHANISM; RNA EXTRACTION; ANIMAL; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION REGULATION; IMMUNOLOGY; METABOLISM; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANIMALS; APOPTOSIS REGULATORY PROTEINS; BLOTTING, WESTERN; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION REGULATION; HUMANS; IMMUNOPRECIPITATION; INTERLEUKIN-10; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; MEMBRANE GLYCOPROTEINS; MICE; MICRORNAS; NF-KAPPA B; POLYMERASE CHAIN REACTION; RECEPTORS, INTERLEUKIN-1; RNA-BINDING PROTEINS; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4; TRANSFECTION;

EID: 75649113377     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.1828     Document Type: Article

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