MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts

Nature

Volumn 456, Issue 7224, 2008, Pages 980-984

  Thum, Thomas ^a   Gross, Carina ^b   Fiedler, Jan ^a   Fischer, Thomas ^b   Kissler, Stephan ^b   Bussen, Markus ^c   Galuppo, Paolo ^a   Just, Steffen ^d   Rottbauer, Wolfgang ^d   Frantz, Stefan ^a   Castoldi, Mirco ^d   Soutschek, Jürgen ^e   Koteliansky, Victor ^f   Rosenwald, Andreas ^a   Basson, M Albert ^g   Licht, Jonathan D ^h   Pena, John T R ⁱ   Rouhanifard, Sara H ⁱ   Muckenthaler, Martina U ^d   Tuschl, Thomas ^a,b   Martin, Gail R ^c   Bauersachs, Johann ^a   Engelhardt, Stefan ^b,j   more..

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b UNIVERSITY OF WÜRZBURG   (Germany)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF HEIDELBERG   (Germany)

^e REGULUS THERAPEUTICS   (United States)

^f ALNYLAM PHARMACEUTICALS   (United States)

^g KING'S COLLEGE LONDON   (United Kingdom)

^h NORTHWESTERN UNIVERSITY   (United States)

ⁱ ROCKEFELLER UNIVERSITY   (United States)

^j TECHNICAL UNIVERSITY OF MUNICH   (Germany)

more..

Author keywords

[No Author keywords available]

Indexed keywords

FIBROBLAST GROWTH FACTOR; MICRORNA; MICRORNA 21; MITOGEN ACTIVATED PROTEIN KINASE; SPROUTY HOMOLOGUE 1; SPROUTY PROTEIN; UNCLASSIFIED DRUG;

BLOOD; CARDIOVASCULAR DISEASE; DISEASE TREATMENT; ENZYME ACTIVITY; GENE EXPRESSION; INHIBITION; RNA; SECRETION; SURVIVAL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; CYTOKINE RELEASE; FIBROBLAST; FIBROSING ALVEOLITIS; GENE SILENCING; HEART FAILURE; HEART FUNCTION; HEART VENTRICLE HYPERTROPHY; HUMAN; HUMAN CELL; IN VIVO STUDY; MALE; MOUSE; MYOCARDIAL DISEASE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; CARDIOMYOPATHIES; CELL LINE; CELL SURVIVAL; CELLS, CULTURED; DISEASE MODELS, ANIMAL; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FIBROBLASTS; GENE SILENCING; HUMANS; MALE; MAP KINASE SIGNALING SYSTEM; MICE; MICE, TRANSGENIC; MICRORNAS; MYOCYTES, CARDIAC; RATS;

EID: 57749168828     PISSN: 00280836     EISSN: 14764679     Source Type: Journal    
DOI: 10.1038/nature07511     Document Type: Article

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