Protein kinase inhibitors in the treatment of pulmonary fibrosis

Current Medicinal Chemistry

Volumn 15, Issue 25, 2008, Pages 2632-2640

  Garneau Tsodikova, Sylvie ^a   Thannickal, Victor J ^b  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Apoptosis; Epithelial cells; Fibroblasts; Fibrosis; Focal adhesion kinase; Protein kinase B; Protein kinase inhibitors; Therapeutics

Indexed keywords

FOCAL ADHESION KINASE; IMATINIB; PROTEIN KINASE; PROTEIN KINASE B; PROTEIN KINASE B INHIBITOR; PROTEIN KINASE INHIBITOR; TRANSFORMING GROWTH FACTOR BETA1;

APOPTOSIS; DRUG EFFICACY; DRUG SELECTIVITY; DRUG TARGETING; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; FIBROSING ALVEOLITIS; GENE EXPRESSION; HUMAN; LUNG ALVEOLUS EPITHELIUM; LUNG FIBROSIS; MESENCHYME CELL; PHENOTYPE; REVIEW; STRUCTURE ACTIVITY RELATION; ANIMAL; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; EPITHELIUM CELL; FIBROBLAST; LUNG; METABOLISM; PATHOLOGY; PHYSIOLOGY;

ANIMALS; APOPTOSIS; EPITHELIAL CELLS; FIBROBLASTS; FOCAL ADHESION PROTEIN-TYROSINE KINASES; HUMANS; LUNG; PHENOTYPE; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-AKT; PULMONARY FIBROSIS;

EID: 58149234456     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: 10.2174/092986708785908969     Document Type: Review

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