Myofibroblast differentiation by transforming growth factor-β1 is dependent on cell adhesion and integrin signaling via focal adhesion kinase

Journal of Biological Chemistry

Volumn 278, Issue 14, 2003, Pages 12384-12389

  Thannickal, Victor J ^a   Lee, Daniel Y ^a   White, Eric S ^a   Cui, Zongbin ^a   Larios, Jose M ^a   Chacon, Raquel ^a   Horowitz, Jeffrey C ^a   Day, Regina M ^b   Thomas, Peedikayil E ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b TUFTS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; DISEASES; ENZYME INHIBITION; TUMORS;

CELL GROWTH;

GROWTH KINETICS;

ALPHA ACTIN; FIBRONECTIN; FOCAL ADHESION KINASE; INTEGRIN; LAMININ; PHENYLALANINE; POLY DEXTRO LYSINE; POLYPEPTIDE; SMAD2 PROTEIN; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TRANSFORMING GROWTH FACTOR BETA1; TYROSINE; FOCAL ADHESION KINASE 1; PROTEIN TYROSINE KINASE; PTK2 PROTEIN, HUMAN; SCLEROPROTEIN; TGFB1 PROTEIN, HUMAN; TRANSFORMING GROWTH FACTOR BETA;

ARTICLE; AUTOPHOSPHORYLATION; CANCER INHIBITION; CELL ADHESION; CELL DIFFERENTIATION; CONTROLLED STUDY; ENZYME ACTIVATION; FETUS; FIBROSIS; HUMAN; HUMAN CELL; HYPERTROPHY; LUNG FIBROBLAST; MYOFIBROBLAST; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; STRESS FIBER; CELL CULTURE; CYTOLOGY; DRUG EFFECT; ENZYMOLOGY; FIBROBLAST; LUNG; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY;

CELL ADHESION; CELL DIFFERENTIATION; CELLS, CULTURED; EXTRACELLULAR MATRIX PROTEINS; FETUS; FIBROBLASTS; FOCAL ADHESION KINASE 1; FOCAL ADHESION PROTEIN-TYROSINE KINASES; HUMANS; INTEGRINS; LUNG; PHOSPHORYLATION; PROTEIN-TYROSINE KINASES; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1;

EID: 0038823614     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M208544200     Document Type: Article

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