MICA polymorphisms and decreased expression of the MICA receptor NKG2D contribute to idiopathic pulmonary fibrosis susceptibility

Human Genetics

Volumn 125, Issue 5-6, 2009, Pages 639-648

  Aquino Galvez, Arnoldo ^a   Pérez Rodríguez, Martha ^b   Camarena, Ángel ^a   Falfan Valencia, Ramces ^a   Ruiz, Víctor ^a   Montaño, Martha ^a   Barrera, Lourdes ^a   Sada Ovalle, Isabel ^a   Ramírez, Remedios ^c   Granados, Julio ^d   Pardo, Annie ^c   Selman, Moisés ^a  

^a INSTITUTO NACIONAL DE ENFERMEDADES RESPIRATORIAS   (Mexico)

^b INSTITUTO MEXICANO DEL SEGURO SOCIAL   (Mexico)

^c UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

^d INSTITUTO NACIONAL DE CIENCIAS MÉDICAS Y NUTRICIÓN SALVADOR ZUBIRÁN   (Mexico)

Author keywords

[No Author keywords available]

Indexed keywords

MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; NATURAL KILLER CELL RECEPTOR NKG2D;

ADULT; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DISEASE PREDISPOSITION; DNA POLYMORPHISM; FEMALE; FIBROSING ALVEOLITIS; FLOW CYTOMETRY; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MAJOR CLINICAL STUDY; MALE; MOLECULAR DYNAMICS; MOLECULAR TYPING; NATURAL KILLER CELL; PANCREAS ISLET DELTA CELL; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN LOCALIZATION; SUPPRESSOR CELL;

ADULT; AGED; CASE-CONTROL STUDIES; CELLS, CULTURED; FEMALE; GENE EXPRESSION; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HISTOCOMPATIBILITY ANTIGENS CLASS I; HLA-B ANTIGENS; HUMANS; IDIOPATHIC PULMONARY FIBROSIS; KILLER CELLS, NATURAL; LUNG; MALE; MIDDLE AGED; NK CELL LECTIN-LIKE RECEPTOR SUBFAMILY K; POLYMORPHISM, GENETIC; SEQUENCE ANALYSIS, DNA; T-LYMPHOCYTE SUBSETS;

EID: 67349165410     PISSN: 03406717     EISSN: 14321203     Source Type: Journal    
DOI: 10.1007/s00439-009-0666-1     Document Type: Article

References (51)

1. American Thoracic Society (2000) Idiopathic pulmonary fibrosis: diagnosis and treatment. International consensus statement. American Thoracic Society (ATS) and the European Respiratory Society (ERS). Am J Respir Crit Care Med 161:646-664
2. Arguello JR, Little AM, Bohan E, Goldman JM, Marsh SGE, Madrigal JA (1998) High resolution HLA class I typing by reference strand mediated conformation analysis (RSCA). Tissue Antigens 52:57-66
3. Barrera L, Mendoza F, Zuñiga J, Estrada A, Zamora AC, Melendro EI, Ramírez R, Pardo A, Selman M (2008) Functional diversity of T-cell subpopulations in subacute and chronic hypersensitivity pneumonitis. Am J Respir Crit Care Med 177:44-55
4. Boissel N, Rea D, Tieng V, Dulphy N, Brun M, Cayuela JM, Rousselot P, Tamouza R, Le Bouteiller P, Mahon FX, Steinle A, Charron D, Dombret H, Toubert A (2006) BCR/ABL oncogene directly controls MHC class I chain-related molecule A expression in chronic myelogenous leukemia. J Immunol 176:5108-5116
5. Borchers MT, Harris NL, Wesselkamper SC, Vitucci M, Cosman D (2006) NKG2D ligands are expressed on stressed human airway epithelial cells. Am J Physiol 291:L222-L231
6. Disis ML, De la Rosa C, Goodell V, Kuan LY, Chang J, Kuus-Reichel K, Clay TM, Lyerly HK, Bhatia S, Ghanekar SA, Maino VC, Maecker HT (2006) Maximizing the retention of antigen specific lymphocyte function after cryopreservation. J Immunol Methods 308:13-18
7. Eisele G, Wischhusen J, Mittelbronn M, Meyermann R, Waldhauer I, Steinle A, Weller M, Friese MA (2006) TGF-b and metalloproteinases differentially suppress NKG2D ligand surface expression on malignant glioma cells. Brain 129:2416-2425
8. Falfán-Valencia R, Camarena A, Juárez A, Becerril C, Montaño M, Cisneros J, Mendoza F, Granados J, Pardo A, Selman M (2005) Major histocompatibility complex and alveolar epithelial apoptosis in idiopathic pulmonary fibrosis. Hum Genet 118:235-244
9. Gao X, Single RM, Karacki P, Marti D, O'Brien SJ, Carrington M (2006) Diversity of MICA and linkage disequilibrium with HLA-B in two North American populations. Human Immunol 67:152-158
10. Groh V, Brühl A, El-Gabalawy H, Nelson JL, Spies T (2003) Stimulation of T cell autoreactivity by anomalous expression of NKG2D and its MIC ligands in rheumatoid arthritis. Proc Natl Acad Sci USA 100:9452-9457
11. Groh V, Li YQ, Cioca D, Hunder NN, Wang W, Riddell SR, Yee C, Spies T (2005) Efficient cross-priming of tumor antigen-specific T cells by dendritic cells sensitized with diverse anti-MICA opsonized tumor cells. Proc Natl Acad Sci USA 102:6461-6466
12. Hui J, Palmer LJ, Jamesw AL, Muskz AW, Beilby JP (2006) AluyMICB dimorphism within the class I region of the major histocompatibility complex is associated with asthma and airflow obstruction in the Busselton population. Clin Exp Allergy 36:728-734
13. Katzenstein AL, Myers JL (1998) Idiopathic pulmonary fibrosis: Clinical relevance of pathologic classification. Am J Respir Crit Care Med 157:1301-1315
14. Katzenstein AL, Mukhopadhyay S, Myers JL (2008) Diagnosis of usual interstitial pneumonia and distinction from other fibrosing interstitial lung diseases. Hum Pathol 39:1275-1294
15. Khalil N, Parekh TV, O'Connor R, Antman N, Kepron W, Yehaulaeshet T, Xu YD, Gold LI (2001) Regulation of the effects of TGF-beta 1 by activation of latent TGF-beta 1 and differential expression of TGF-beta receptors (T beta R-I and T beta R-II) in idiopathic pulmonary fibrosis. Thorax 56:907-915
16. Kim KK, Kugler MC, Wolters PJ, Robillard L, Galvez MG, Brumwell AN, Sheppard D, Chapman HA (2006) Alveolar epithelial cell mesenchymal transition develops in vivo during pulmonary fibrosis and is regulated by the extracellular matrix. Proc Natl Acad Sci USA 103:13180-13185
17. Kinnula VL, Fattman CL, Tan RJ, Oury TD (2005) Oxidative stress in pulmonary fibrosis: A possible role for redox modulatory therapy. Am J Respir Crit Care Med 172:417-422
18. Komatsu-Wakui M, Itsohkikuanwaaga YK, Leelayuwat C, Kashiwase K, Tanaka S, Moriyama H, Nakajima F, Park MH, Jia GJ, Chimge N-O, Sideltseva EW, Juji T (2001) Wide distribution of the MICA-MICB null haplotype in East Asians. Tissue Antigens 57:1-8
19. Lawson WE, Loyd JE (2006) The genetic approach in pulmonary fibrosis: can it provide clues to this complex disease? Proc Am Thorac Soc 3:345-349
20. Lee JC, Lee KM, Kim DW, Heo DS (2004) Elevated TGF-beta1 secretion and down-modulation of NKG2D underlies impaired NK cytotoxicity in cancer patients. J Immunol 172:7335-7340
21. Lü M, Xia B, Li J, Ye M, Zhang X, Tan Q (2006) MICB microsatellite polymorphism is associated with ulcerative colitis in Chinese population. Clin Immunol 120:199-204
22. Madjd Z, Spendlove I, Moss R, Bevin S, Pinder SE, Watson NFS, Ellis I, Durrant LG (2007) Upregulation of MICA on high-grade invasive operable breast carcinoma. Cancer Immun 7:17
23. Muñoz-Saá I, Cambra A, Pallarés L, Espinosa G, Juan A, Pujalte F, Matamoros N, Mila J, Julia MR (2005) Allelic diversity and affinity variants of MICA are imbalanced in Spanish patients with Behcet's disease. Scand J Immunol 64:77-82
24. Osaki T, Saito H, Yoshikawa T, Matsumoto S, Tatebe S, Tsujitani S, Ikeguchi M (2007) Decreased NKG2D expression on CD8+ T cell is involved in immune evasion in patients with gastric cancer. Clin Cancer Res 13:382-387
25. Pardo A, Barrios R, Maldonado V, Meléndez J, Pérez J, Ruíz V, Segura L, Sznajder JI, Selman M (1998) Gelatinases A and B are upregulated in lung rats by subacute hyperoxia. Pathogenetic implications. Am J Pathol 153:833-844
26. Peraldi MN, Berrou J, Dulphy N, Seidowsky A, Haas P, Boissel N, Metivier F, Randoux C, Kossari N, Guérin A, Geffroy S, Delavaud G, Marin-Esteban V, Glotz D, Charron D, Toubert A (2009) Oxidative stress mediates a reduced expression of the activating receptor NKG2D in NK cells from end-stage renal disease patients. J Immunol 182:1696-1705
27. Pérez-Rodríguez M, Argüello JR, Fischer G, Corell A, Cox ST, Robinson J, Hossain E, McWhinnie A, Travers PJ, Marsh SGE, Madrigal JA (2002) Further polymorphism of the MICA gene. Eur J Immunogenetics 29:35-46
28. Piancatelli D, Del Beato T, Oumhani K, El Aouad R, Adorno D (2005) MICA polymorphism in a population from north Morocco, Metalsa Berbers, using sequence-based typing. Human Immunol 66:931-936
29. Poggi A, Prevosto C, Zancolli M, Canevali P, Musso A, Zocchi MR (2007) NKG2D and natural cytotoxicity receptors are involved in natural killer cell interaction with self-antigen presenting cells and stromal cells. Ann N Y Acad Sci 1109:47-57
30. Raffaghello L, Prigione I, Airoldi I, Camoriano M, Levreri I, Gambini C, Pende D, Steinle A, Ferrone S, Pistoia V (2004) Downregulation and/or release of NKG2D ligands as immune evasion strategy of human neuroblastoma. Neoplasia 6:558-568
31. Robinson P, Stuber D, Deryckere F, Tedbury P, Lagrange M, Orfanoudakis G (2005) Identification using phage display of peptides promoting targeting and internalization into HPV-transformed cell lines. J Mol Recognit 18:175-182
32. Selman M, Pardo A (2006) Role of epithelial cells in idiopathic pulmonary fibrosis: From innocent targets to serial killers. Proc Am Thorac Soc 3:364-372
33. Selman M, King TE, Pardo A (2001) Idiopathic pulmonary fibrosis: prevailing and evolving hypotheses about its pathogenesis and implications for therapy. Ann Intern Med 134:136-151
34. Selman M, Thannickal VJ, Pardo A, Zisman DA, Martinez FJ, Lynch JP 3rd (2004) Idiopathic pulmonary fibrosis: Pathogenesis and therapeutic approaches. Drugs 64:405-430
35. Selman M, Pardo A, Barrera L, Estrada A, Watson SR, Wilson K, Aziz N, Kaminski N, Zlotnik A (2006) Gene expression profiles distinguish idiopathic pulmonary fibrosis from hypersensitivity pneumonitis. Am J Respir Crit Care Med 173:188-198
36. Selman M, Carrillo G, Estrada A, Mejia M, Becerril C, Cisneros J, Gaxiola M, Pérez-Padilla R, Navarro C, Richards T, Dauber J, King TE Jr, Pardo A, Kaminski N (2007) Accelerated variant of idiopathic pulmonary fibrosis: Clinical behavior and gene expression pattern. PLoS ONE 2(5):e482
37. Skov S, Terndrup PM, Andresen L, Thor SP, Woetmann A, Ødum N (2005) Cancer cells become susceptible to natural killer cell killing after exposure to histone deacetylase Inhibitors due to glycogen synthase kinase-3-dependent expression of MHC class I-related chain A and B. Cancer Res 65:11136-11145
38. Stastny P (2006) Introduction: MICA/MICB in innate immunity, adaptive immunity, autoimmunity, cancer, and in the immune response to transplants. Hum Immunol 67:141-144
39. Steinle A, Li P, Morris DL, Groh V, Lanier LL, Strong RK, Spies T (2001) Interactions of human NKG2D with its ligands MICA, MICB, and homologs of the mouse RAE-1 protein family. Immunogenetics 53:279-287
40. Suemizu H, Radosavljevic M, Kimura M, Sadahiro S, Yoshimura S, Bahram S, Inoko H (2002) A basolateral sorting motif in the MICA cytoplasmic tail. Proc Natl Acad Sci USA 99:2971-2976
41. Tamaki S, Kawakami M, Yamanaka Y, Shimomura H, Imai Y, Ishida JI, Yamamoto K, Ishitani A, Hatake K, Kirita T (2008) Relationship between soluble MICA and the MICA A5.1 homozygous genotype in patients with oral squamous cell carcinoma. Clin Immunol 130:331-337
42. Thannickal VJ, Horowitz JC (2006) Evolving concepts of apoptosis in idiopathic pulmonary fibrosis. Proc Am Thorac Soc 3:350-356
43. Törn C, Gupta M, Zake LN, Sanjeevi CB, Landin-Olsson M (2003) Heterozygosity for MICA5.0/MICA5.1 and HLA-DR3-DQ2/DR4-DQ8 are Independent genetic risk factors for latent autoimmune diabetes in adults. Human Immunol 64:902-909
44. Waldhauer I, Steinle A (2006) Proteolytic release of soluble UL16-binding protein 2 from tumor cells. Cancer Res 66:2520-2526
45. Waldhauer I, Goehlsdorf D, Gieseke F, Weinschenk T, Wittenbrink M, Ludwig A, Stevanovic S, Rammensee HG, Steinle A (2008) Tumor-associated MICA is shed by ADAM proteases. Cancer Res 68:6368-6376
46. Willis BC, Liebler JM, Luby-Phelps K, Nicholson AG, Crandall ED, du Bois RM, Borok Z (2005) Induction of epithelial-mesenchymal transition in alveolar epithelial cells by transforming growth factor-beta1: Potential role in idiopathic pulmonary fibrosis. Am J Pathol 166:1321-1332
47. Wu J, Groh V, Spies T (2002) T Cell antigen receptor engagement and specificity in the recognition of stress-inducible MHC class I-related chains by human epithelial γδ T cells. J Immunol 169:1236-1240
48. Xu X, Rao G, Gaffud MJ, Ding HG, Maki G, Klingemann H-G, Groh V, Spies T, Sp Caillat-Zucman, Gattuso P, Plate J, Prinz RA (2006) Clinicopathological significance of major histocompatibility complex class I-related chain A and B expression in thyroid cancer. J Clin Endocrinol Metab 91:2704-2712
49. Zhang T, Barber A, Sentman CL (2006) Generation of antitumor responses by genetic modification of primary human T cells with a chimeric NKG2D receptor. Cancer Res 66:5927-5933
50. Zhang S, Hüe S, Sène D, Penfornis A, Bresson-Hadni S, Kantelip B, Caillat-Zucman S, Vuitton DA (2008) Expression of major histocompatibility complex class I chain-related molecule A, NKG2D, and transforming growth factor-beta in the liver of humans with alveolar echinococcosis: New actors in the tolerance to parasites? J Infect Dis 197:1341-1349
51. Zou Y, Mirbaha F, Stastny P (2006) Contact inhibition causes strong downregulation of expression of MICA in human fibroblasts and decreased NK Cell killing. Human Immunol 67:183-187