Latent transforming growth factor-β-binding protein-4 regulates transforming growth factor-β1 bioavailability for activation by fibrogenic lung fibroblasts in response to bleomycin

American Journal of Pathology

Volumn 174, Issue 1, 2009, Pages 21-33

  Zhou, Yong ^a   Koli, Katri ^c   Hagood, James S ^b   Miao, Mi ^a   Mavalli, Mahendra ^a   Rifkin, Daniel B ^d   Murphy Ullrich, Joanne E ^a,b,e  

^a University of Alabama at Birmingham   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c UNIVERSITY OF HELSINKI   (Finland)

^d NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLEOMYCIN; INTERLEUKIN 4; LATENT TRANSFORMING GROWTH FACTOR BETA BINDING PROTEIN; LATENT TRANSFORMING GROWTH FACTOR BETA BINDING PROTEIN 4; MESSENGER RNA; SMAD3 PROTEIN; SMALL INTERFERING RNA; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING SITE; BIOAVAILABILITY; CONTROLLED STUDY; DENSITOMETRY; DISEASE PREDISPOSITION; EXTRACELLULAR MATRIX; FEMALE; FIBROGENESIS; GENE ACTIVATION; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; KNOCKOUT MOUSE; LUNG FIBROBLAST; LUNG FIBROSIS; MORPHOMETRICS; MOUSE; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING; WILD TYPE;

EID: 58249098406     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.2353/ajpath.2009.080620     Document Type: Article

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