Y-27632 prevents tubulointerstitial fibrosis in mouse kidneys with unilateral ureteral obstruction

Kidney International

Volumn 61, Issue 5, 2002, Pages 1684-1695

  Nagatoya, Katsuyuki ^a,b   Moriyama, Toshiki ^a,b   Kawada, Noritaka ^a,b   Takeji, Masanobu ^a,b   Oseto, Susumu ^a,b   Murozono, Takahiro ^a,b   Ando, Akio ^a,b   Imai, Enyu ^a,b   Hori, Masatsugu ^a,b  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b MITSUBISHI TANABE PHARMA CORPORATION   (Japan)

Author keywords

Cell proliferation; Progressive renal disease; Renal fibrosis; Rho ROCK pathway; Tissue fibrosis; Tubulointerstitial fibrosis

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; ALPHA ACTIN; CHEMOATTRACTANT; COLLAGEN; INTERCELLULAR ADHESION MOLECULE 1; OSTEOPONTIN; RHO KINASE; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; GENE EXPRESSION; IN VITRO STUDY; IN VIVO STUDY; KIDNEY FIBROSIS; MACROPHAGE; MALE; MOUSE; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; URETER OBSTRUCTION;

EID: 0036236193     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.2002.00328.x     Document Type: Article

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