-
1
-
-
0037080547
-
American Thoracic Society/European Respiratory Society: International multidisciplinary consensus classification of the idiopathic interstitial pneumonias
-
American Thoracic Society and European Respiratory Society. American Thoracic Society/European Respiratory Society: international multidisciplinary consensus classification of the idiopathic interstitial pneumonias. Am J Respir Crit Care Med 2002;165:277-304.
-
(2002)
Am J Respir Crit Care Med
, vol.165
, pp. 277-304
-
-
-
3
-
-
1542411333
-
Idiopathic pulmonary fibrosis: Pathogenesis and therapeutic approaches
-
Selman M, Thannickal VJ, Pardo A, Zisman DA, Martinez FJ, Lynch JP III. Idiopathic pulmonary fibrosis: pathogenesis and therapeutic approaches. Drugs 2004;64:405-430.
-
(2004)
Drugs
, vol.64
, pp. 405-430
-
-
Selman, M.1
Thannickal, V.J.2
Pardo, A.3
Zisman, D.A.4
Martinez, F.J.5
Lynch III, J.P.6
-
4
-
-
0345824715
-
A placebo-controlled trial of interferon gamma-1b in patients with idiopathic pulmonary fibrosis
-
Raghu G, Brown KK, Bradford WZ, Starko K, Noble PW, Schwartz DA, King TE Jr. A placebo-controlled trial of interferon gamma-1b in patients with idiopathic pulmonary fibrosis. N Engl J Med 2004;350: 125-133.
-
(2004)
N Engl J Med
, vol.350
, pp. 125-133
-
-
Raghu, G.1
Brown, K.K.2
Bradford, W.Z.3
Starko, K.4
Noble, P.W.5
Schwartz, D.A.6
King Jr., T.E.7
-
5
-
-
18244383070
-
Clinical significance of histological classification of idiopathic interstitial pneumonia
-
Flaherty KR, Toews GB, Travis WD, Colby TV, Kazerooni EA, Gross BH, Jain A, Strawderman RL III, Paine R, Flint A, et al. Clinical significance of histological classification of idiopathic interstitial pneumonia. Eur Respir J 2002;19:275-283.
-
(2002)
Eur Respir J
, vol.19
, pp. 275-283
-
-
Flaherty, K.R.1
Toews, G.B.2
Travis, W.D.3
Colby, T.V.4
Kazerooni, E.A.5
Gross, B.H.6
Jain, A.7
Strawderman III, R.L.8
Paine, R.9
Flint, A.10
-
6
-
-
0029051473
-
Generation and disposal of reactive oxygen metabolites in the lung
-
Kinnula VL, Crapo JD, Raivio KO. Generation and disposal of reactive oxygen metabolites in the lung. Lab Invest 1995;73:3-19.
-
(1995)
Lab Invest
, vol.73
, pp. 3-19
-
-
Kinnula, V.L.1
Crapo, J.D.2
Raivio, K.O.3
-
7
-
-
0038545583
-
Superoxide dismutases in the lung and human lung diseases
-
Kinnula VL, Crapo JD. Superoxide dismutases in the lung and human lung diseases. Am J Respir Crit Care Med 2003;167:1600-1619.
-
(2003)
Am J Respir Crit Care Med
, vol.167
, pp. 1600-1619
-
-
Kinnula, V.L.1
Crapo, J.D.2
-
8
-
-
0033796101
-
The role of the redox protein thioredoxin in cell growth and cancer
-
Powis G, Mustacich D, Coon A. The role of the redox protein thioredoxin in cell growth and cancer. Free Radic Biol Med 2000;29:312-322.
-
(2000)
Free Radic Biol Med
, vol.29
, pp. 312-322
-
-
Powis, G.1
Mustacich, D.2
Coon, A.3
-
10
-
-
9444249870
-
The transcription factor NRF2 protects against pulmonary fibrosis
-
Cho HY, Reddy SP, Yamamoto M, Kleeberger SR. The transcription factor NRF2 protects against pulmonary fibrosis. FASEB J 2004;18: 1258-1260.
-
(2004)
FASEB J
, vol.18
, pp. 1258-1260
-
-
Cho, H.Y.1
Reddy, S.P.2
Yamamoto, M.3
Kleeberger, S.R.4
-
11
-
-
0023263236
-
Oxidant-mediated epithelial cell injury in idiopathic pulmonary fibrosis
-
Cantin AM, North SL, Fells GA, Hubbard RC, Crystal RG. Oxidant-mediated epithelial cell injury in idiopathic pulmonary fibrosis. J Clin Invest 1987;79:1665-1673.
-
(1987)
J Clin Invest
, vol.79
, pp. 1665-1673
-
-
Cantin, A.M.1
North, S.L.2
Fells, G.A.3
Hubbard, R.C.4
Crystal, R.G.5
-
12
-
-
0024581879
-
The eosinophil component of the alveolitis in idiopathic pulmonary fibrosis: Signs of eosinophil activation in the lung are related to impaired lung function
-
Hallgren R, Bjermer L, Lundgren R, Venge P. The eosinophil component of the alveolitis in idiopathic pulmonary fibrosis: signs of eosinophil activation in the lung are related to impaired lung function. Am Rev Respir Dis 1989;139:373-377.
-
(1989)
Am Rev Respir Dis
, vol.139
, pp. 373-377
-
-
Hallgren, R.1
Bjermer, L.2
Lundgren, R.3
Venge, P.4
-
13
-
-
0036905316
-
Mitochondria-mediated apoptosis of lung epithelial cells in idiopathic interstitial pneumonias
-
Kuwano K, Hagimoto N, Maeyama T, Fujita M, Yoshimi M, Inoshima I, Nakashima N, Hamada N, Watanabe K, Hara N. Mitochondria-mediated apoptosis of lung epithelial cells in idiopathic interstitial pneumonias. Lab Invest 2002;82:1695-1706.
-
(2002)
Lab Invest
, vol.82
, pp. 1695-1706
-
-
Kuwano, K.1
Hagimoto, N.2
Maeyama, T.3
Fujita, M.4
Yoshimi, M.5
Inoshima, I.6
Nakashima, N.7
Hamada, N.8
Watanabe, K.9
Hara, N.10
-
14
-
-
12244286790
-
Oxidative stress in lung epithelial cells from patients with idiopathic interstitial pneumonias
-
Kuwano K, Nakashima N, Inoshima I, Hagimoto N, Fujita M, Yoshimi M, Maeyama T, Hamada N, Watanabe K, Hara N. Oxidative stress in lung epithelial cells from patients with idiopathic interstitial pneumonias. Eur Respir J 2003;21:232-240.
-
(2003)
Eur Respir J
, vol.21
, pp. 232-240
-
-
Kuwano, K.1
Nakashima, N.2
Inoshima, I.3
Hagimoto, N.4
Fujita, M.5
Yoshimi, M.6
Maeyama, T.7
Hamada, N.8
Watanabe, K.9
Hara, N.10
-
15
-
-
0031761169
-
8-Isoprostane as a biomarker of oxidative stress in interstitial lung diseases
-
Montuschi P, Ciabattoni G, Paredi P, Pantelidis P, du Bois RM, Kharitonov SA, Barnes PJ. 8-Isoprostane as a biomarker of oxidative stress in interstitial lung diseases. Am J Respir Crit Care Med 1998;158:1524-1527.
-
(1998)
Am J Respir Crit Care Med
, vol.158
, pp. 1524-1527
-
-
Montuschi, P.1
Ciabattoni, G.2
Paredi, P.3
Pantelidis, P.4
Du Bois, R.M.5
Kharitonov, S.A.6
Barnes, P.J.7
-
17
-
-
0036142953
-
Inducible nitric oxide synthase, but not xanthine oxidase, is highly expressed in interstitial pneumonias and granulomatous diseases of human lung
-
Lakari E, Soini Y, Saily M, Koistinen P, Paakko P, Kinnula VL. Inducible nitric oxide synthase, but not xanthine oxidase, is highly expressed in interstitial pneumonias and granulomatous diseases of human lung. Am J Clin Pathol 2002;117:132-142.
-
(2002)
Am J Clin Pathol
, vol.117
, pp. 132-142
-
-
Lakari, E.1
Soini, Y.2
Saily, M.3
Koistinen, P.4
Paakko, P.5
Kinnula, V.L.6
-
18
-
-
0030915094
-
Increased production of the potent oxidant peroxynitrite in the lungs of patients with idiopathic pulmonary fibrosis
-
Saleh D, Barnes PJ, Giaid A. Increased production of the potent oxidant peroxynitrite in the lungs of patients with idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 1997;155:1763-1769.
-
(1997)
Am J Respir Crit Care Med
, vol.155
, pp. 1763-1769
-
-
Saleh, D.1
Barnes, P.J.2
Giaid, A.3
-
19
-
-
0029148261
-
Increased oxidation of extracellular glutathione by bronchoalveolar inflammatory cells in diffuse fibrosing alveolitis
-
Behr J, Degenkolb B, Maier K, Braun B, Beinert T, Krombach F, Vogelmeier C, Fruhmann G. Increased oxidation of extracellular glutathione by bronchoalveolar inflammatory cells in diffuse fibrosing alveolitis. Eur Respir J 1995;8:1286-1292.
-
(1995)
Eur Respir J
, vol.8
, pp. 1286-1292
-
-
Behr, J.1
Degenkolb, B.2
Maier, K.3
Braun, B.4
Beinert, T.5
Krombach, F.6
Vogelmeier, C.7
Fruhmann, G.8
-
20
-
-
0036014536
-
Intracellular glutathione and bronchoalveolar cells in fibrosing alveolitis: Effects of N-acetylcysteine
-
Behr J, Degenkolb B, Krombach F, Vogelmeier C. Intracellular glutathione and bronchoalveolar cells in fibrosing alveolitis: effects of N-acetylcysteine. Eur Respir J 2002;19:906-911.
-
(2002)
Eur Respir J
, vol.19
, pp. 906-911
-
-
Behr, J.1
Degenkolb, B.2
Krombach, F.3
Vogelmeier, C.4
-
21
-
-
0024578662
-
Glutathione deficiency in the epithelial lining fluid of the lower respiratory tract in idiopathic pulmonary fibrosis
-
Cantin AM, Hubbard RC, Crystal RG. Glutathione deficiency in the epithelial lining fluid of the lower respiratory tract in idiopathic pulmonary fibrosis. Am Rev Respir Dis 1989;139:370-372.
-
(1989)
Am Rev Respir Dis
, vol.139
, pp. 370-372
-
-
Cantin, A.M.1
Hubbard, R.C.2
Crystal, R.G.3
-
22
-
-
0025886739
-
Effect of glutathione aerosol on oxidant-antioxidant imbalance in idiopathic pulmonary fibrosis
-
Borok Z, Buhl R, Grimes GJ, Bokser AD, Hubbard RC, Holroyd KJ, Roum JH, Czerski DB, Cantin AM, Crystal RG. Effect of glutathione aerosol on oxidant-antioxidant imbalance in idiopathic pulmonary fibrosis. Lancet 1991;338:215-216.
-
(1991)
Lancet
, vol.338
, pp. 215-216
-
-
Borok, Z.1
Buhl, R.2
Grimes, G.J.3
Bokser, A.D.4
Hubbard, R.C.5
Holroyd, K.J.6
Roum, J.H.7
Czerski, D.B.8
Cantin, A.M.9
Crystal, R.G.10
-
23
-
-
0242558977
-
Expression of the thioredoxin system in interstitial lung disease
-
Tiitto L, Kaarteenaho-Wiik R, Sormunen R, Holmgren A, Paakko P, Soini Y, Kinnula VL. Expression of the thioredoxin system in interstitial lung disease. J Pathol 2003;201:363-370.
-
(2003)
J Pathol
, vol.201
, pp. 363-370
-
-
Tiitto, L.1
Kaarteenaho-Wiik, R.2
Sormunen, R.3
Holmgren, A.4
Paakko, P.5
Soini, Y.6
Kinnula, V.L.7
-
24
-
-
3843142866
-
Expression of glutaredoxin is highly cell specific in human lung and is decreased by transforming growth factor-beta in vitro and in interstitial lung diseases in vivo
-
Peltoniemi M, Kaarteenaho-Wiik R, Saily M, Sormunen R, Paakko P, Holmgren A, Soini Y, Kinnula VL. Expression of glutaredoxin is highly cell specific in human lung and is decreased by transforming growth factor-beta in vitro and in interstitial lung diseases in vivo. Hum Pathol 2004;35:1000-1007.
-
(2004)
Hum Pathol
, vol.35
, pp. 1000-1007
-
-
Peltoniemi, M.1
Kaarteenaho-Wiik, R.2
Saily, M.3
Sormunen, R.4
Paakko, P.5
Holmgren, A.6
Soini, Y.7
Kinnula, V.L.8
-
25
-
-
0343415706
-
Manganese superoxide dismutase and catalase are coordinated expressed in the alveolar region in chronic interstitial pneumonias and granulomatous diseases of the lung
-
Lakari E, Paakko P, Pietarinen-Runtti P, Kinnula VL. Manganese superoxide dismutase and catalase are coordinated expressed in the alveolar region in chronic interstitial pneumonias and granulomatous diseases of the lung. Am J Respir Crit Care Med 2000;161:615-621.
-
(2000)
Am J Respir Crit Care Med
, vol.161
, pp. 615-621
-
-
Lakari, E.1
Paakko, P.2
Pietarinen-Runtti, P.3
Kinnula, V.L.4
-
26
-
-
0035179226
-
Expression and regulation of hemeoxygenase 1 in healthy human lung and interstitial lung disorders
-
Lakari E, Pylkas P, Pietarinen-Runtti P, Paakko P, Soini Y, Kinnula VL. Expression and regulation of hemeoxygenase 1 in healthy human lung and interstitial lung disorders. Hum Pathol 2001;32:1257-1263.
-
(2001)
Hum Pathol
, vol.32
, pp. 1257-1263
-
-
Lakari, E.1
Pylkas, P.2
Pietarinen-Runtti, P.3
Paakko, P.4
Soini, Y.5
Kinnula, V.L.6
-
27
-
-
18344396051
-
Gene expression analysis reveals matrilysin as a key regulator of pulmonary fibrosis in mice and humans
-
Zuo F, Kaminski N, Eugui E, Allard J, Yakhini Z, Ben Dor A, Lollini L, Morris D, Kim Y, DeLustro B, et al. Gene expression analysis reveals matrilysin as a key regulator of pulmonary fibrosis in mice and humans. Proc Natl Acad Sci USA 2002;99:6292-6297.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 6292-6297
-
-
Zuo, F.1
Kaminski, N.2
Eugui, E.3
Allard, J.4
Yakhini, Z.5
Ben Dor, A.6
Lollini, L.7
Morris, D.8
Kim, Y.9
DeLustro, B.10
-
28
-
-
0033679330
-
Characteristic elevation of matrix metalloproteinase activity in idiopathic interstitial pneumonias
-
Suga M, Iyonaga K, Okamoto T, Gushima Y, Miyakawa H, Akaike T, Ando M. Characteristic elevation of matrix metalloproteinase activity in idiopathic interstitial pneumonias. Am J Respir Crit Care Med 2000; 162:1949-1956.
-
(2000)
Am J Respir Crit Care Med
, vol.162
, pp. 1949-1956
-
-
Suga, M.1
Iyonaga, K.2
Okamoto, T.3
Gushima, Y.4
Miyakawa, H.5
Akaike, T.6
Ando, M.7
-
29
-
-
4043161974
-
Mitochondrial redox control of matrix metalloproteinases
-
Nelson KK, Melendez JA. Mitochondrial redox control of matrix metalloproteinases. Free Radic Biol Med 2004;37:768-784.
-
(2004)
Free Radic Biol Med
, vol.37
, pp. 768-784
-
-
Nelson, K.K.1
Melendez, J.A.2
-
30
-
-
0042093741
-
Hypochlorous acid generated by myeloperoxidase modifies adjacent tryptophan and glycine residues in the catalytic domain of matrix metalloproteinase-7 (matrilysin): An oxidative mechanism for restraining proteolytic activity during inflammation
-
Fu X, Kassim SY, Parks WC, Heinecke JW. Hypochlorous acid generated by myeloperoxidase modifies adjacent tryptophan and glycine residues in the catalytic domain of matrix metalloproteinase-7 (matrilysin): an oxidative mechanism for restraining proteolytic activity during inflammation. J Biol Chem 2003;278:28403-28409.
-
(2003)
J Biol Chem
, vol.278
, pp. 28403-28409
-
-
Fu, X.1
Kassim, S.Y.2
Parks, W.C.3
Heinecke, J.W.4
-
31
-
-
3543134126
-
Matrix metalloproteinases as modulators of inflammation and innate immunity
-
Parks WC, Wilson CL, Lopez-Boado YS. Matrix metalloproteinases as modulators of inflammation and innate immunity. Nat Rev Immunol 2004;4:617-629.
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 617-629
-
-
Parks, W.C.1
Wilson, C.L.2
Lopez-Boado, Y.S.3
-
32
-
-
0000869432
-
Extracellular glutathione peroxidase in human lung epithelial lining fluid and in lung cells
-
Avissar N, Finkelstein JN, Horowitz S, Willey JC, Coy E, Frampton MW, Watkins RH, Khullar P, Xu YL, Cohen HJ. Extracellular glutathione peroxidase in human lung epithelial lining fluid and in lung cells. Am J Physiol 1996;270:L173-L182.
-
(1996)
Am J Physiol
, vol.270
-
-
Avissar, N.1
Finkelstein, J.N.2
Horowitz, S.3
Willey, J.C.4
Coy, E.5
Frampton, M.W.6
Watkins, R.H.7
Khullar, P.8
Xu, Y.L.9
Cohen, H.J.10
-
33
-
-
0032877394
-
Ethanol ingestion increases activation of matrix metalloproteinases in rat lungs during acute endotoxemia
-
Lois M, Brown LA, Moss IM, Roman J, Guidot DM. Ethanol ingestion increases activation of matrix metalloproteinases in rat lungs during acute endotoxemia. Am J Respir Crit Care Med 1999;160:1354-1360.
-
(1999)
Am J Respir Crit Care Med
, vol.160
, pp. 1354-1360
-
-
Lois, M.1
Brown, L.A.2
Moss, I.M.3
Roman, J.4
Guidot, D.M.5
-
34
-
-
11144355699
-
Extracellular superoxide dismutase (ECSOD) binds to type I collagen and protects against oxidative fragmentation
-
Petersen SV, Oury TD, Ostergaard L, Valnickova Z, Wegrzyn J, Thogersen IB, Jacobsen C, Bowler RP, Fattman CL, Crapo JD, et al. Extracellular superoxide dismutase (ECSOD) binds to type I collagen and protects against oxidative fragmentation. J Biol Chem 2004;279:13705-13710.
-
(2004)
J Biol Chem
, vol.279
, pp. 13705-13710
-
-
Petersen, S.V.1
Oury, T.D.2
Ostergaard, L.3
Valnickova, Z.4
Wegrzyn, J.5
Thogersen, I.B.6
Jacobsen, C.7
Bowler, R.P.8
Fattman, C.L.9
Crapo, J.D.10
-
35
-
-
0035890010
-
Altered expression of extracellular superoxide dismutase in mouse lung after bleomycin treatment
-
Fattman CL, Chu CT, Kulich SM, Enghild JJ, Oury TD. Altered expression of extracellular superoxide dismutase in mouse lung after bleomycin treatment. Free Radic Biol Med 2001;31:1198-1207.
-
(2001)
Free Radic Biol Med
, vol.31
, pp. 1198-1207
-
-
Fattman, C.L.1
Chu, C.T.2
Kulich, S.M.3
Enghild, J.J.4
Oury, T.D.5
-
37
-
-
0030028593
-
Inactivation of tissue inhibitor of metalloproteinase-1 by peroxynitrite
-
Frears ER, Zhang Z, Blake DR, O'Connell JP, Winyard PG. Inactivation of tissue inhibitor of metalloproteinase-1 by peroxynitrite. FEBS Lett 1996;381:21-24.
-
(1996)
FEBS Lett
, vol.381
, pp. 21-24
-
-
Frears, E.R.1
Zhang, Z.2
Blake, D.R.3
O'Connell, J.P.4
Winyard, P.G.5
-
38
-
-
0344564123
-
Mechanism of hypochlorite-mediated inactivation of proteinase inhibition by alpha 2-macroglobulin
-
Wu SM, Pizzo SV. Mechanism of hypochlorite-mediated inactivation of proteinase inhibition by alpha 2-macroglobulin. Biochemistry 1999;38: 13983-13990.
-
(1999)
Biochemistry
, vol.38
, pp. 13983-13990
-
-
Wu, S.M.1
Pizzo, S.V.2
-
39
-
-
0030029719
-
Administration of truncated secretory leukoprotease inhibitor ameliorates bleomycin-induced pulmonary fibrosis in hamsters
-
Mitsuhashi H, Asano S, Nonaka T, Hamamura I, Masuda K, Kiyoki M. Administration of truncated secretory leukoprotease inhibitor ameliorates bleomycin-induced pulmonary fibrosis in hamsters. Am J Respir Crit Care Med 1996;153:369-374.
-
(1996)
Am J Respir Crit Care Med
, vol.153
, pp. 369-374
-
-
Mitsuhashi, H.1
Asano, S.2
Nonaka, T.3
Hamamura, I.4
Masuda, K.5
Kiyoki, M.6
-
40
-
-
0026782383
-
Inactivation of alpha 1-proteinase inhibitor by peroxynitrite
-
Moreno JJ, Pryor WA. Inactivation of alpha 1-proteinase inhibitor by peroxynitrite. Chem Res Toxicol 1992;5:425-431.
-
(1992)
Chem Res Toxicol
, vol.5
, pp. 425-431
-
-
Moreno, J.J.1
Pryor, W.A.2
-
41
-
-
0026551582
-
Administration of alpha 1-proteinase inhibitor ameliorates bleomycin-induced pulmonary fibrosis in hamsters
-
Nagai A, Aoshiba K, Ishihara Y, Inano H, Sakamoto K, Yamaguchi E, Kagawa J, Takizawa T. Administration of alpha 1-proteinase inhibitor ameliorates bleomycin-induced pulmonary fibrosis in hamsters. Am Rev Respir Dis 1992;145:651-656.
-
(1992)
Am Rev Respir Dis
, vol.145
, pp. 651-656
-
-
Nagai, A.1
Aoshiba, K.2
Ishihara, Y.3
Inano, H.4
Sakamoto, K.5
Yamaguchi, E.6
Kagawa, J.7
Takizawa, T.8
-
42
-
-
2342496439
-
Transforming growth factor type beta induces monocyte chemotaxis and growth factor production
-
Wahl SM, Hunt DA, Wakefield LM, McCartney-Francis N, Wahl LM, Roberts AB, Sporn MB. Transforming growth factor type beta induces monocyte chemotaxis and growth factor production. Proc Natl Acad Sci USA 1987;84:5788-5792.
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 5788-5792
-
-
Wahl, S.M.1
Hunt, D.A.2
Wakefield, L.M.3
McCartney-Francis, N.4
Wahl, L.M.5
Roberts, A.B.6
Sporn, M.B.7
-
43
-
-
0038823614
-
Myofibroblast differentiation by transforming growth factor-beta1 is dependent on cell adhesion and integrin signaling via focal adhesion kinase
-
Thannickal VJ, Lee DY, White ES, Cui Z, Larios JM, Chacon R, Horowitz JC, Day RM, Thomas PE. Myofibroblast differentiation by transforming growth factor-beta1 is dependent on cell adhesion and integrin signaling via focal adhesion kinase. J Biol Chem 2003;278:12384-12389.
-
(2003)
J Biol Chem
, vol.278
, pp. 12384-12389
-
-
Thannickal, V.J.1
Lee, D.Y.2
White, E.S.3
Cui, Z.4
Larios, J.M.5
Chacon, R.6
Horowitz, J.C.7
Day, R.M.8
Thomas, P.E.9
-
44
-
-
0036277026
-
Myofibroblasts and mechano-regulation of connective tissue remodelling
-
Tomasek JJ, Gabbiani G, Hinz B, Chaponnier C, Brown RA. Myofibroblasts and mechano-regulation of connective tissue remodelling. Nat Rev Mol Cell Biol 2002;3:349-363.
-
(2002)
Nat Rev Mol Cell Biol
, vol.3
, pp. 349-363
-
-
Tomasek, J.J.1
Gabbiani, G.2
Hinz, B.3
Chaponnier, C.4
Brown, R.A.5
-
45
-
-
0036086293
-
Smad3 deficiency attenuates bleomycin-induced pulmonary fibrosis in mice
-
Zhao J, Shi W, Wang YL, Chen H, Bringas P Jr, Datto MB, Frederick JP, Wang XF, Warburton D. Smad3 deficiency attenuates bleomycin-induced pulmonary fibrosis in mice. Am J Physiol Lung Cell Mol Physiol 2002;282:L585-L593.
-
(2002)
Am J Physiol Lung Cell Mol Physiol
, vol.282
-
-
Zhao, J.1
Shi, W.2
Wang, Y.L.3
Chen, H.4
Bringas Jr., P.5
Datto, M.B.6
Frederick, J.P.7
Wang, X.F.8
Warburton, D.9
-
46
-
-
1542329010
-
Mechanisms of pulmonary fibrosis
-
Thannickal VJ, Toews GB, White ES, Lynch JP III, Martinez FJ. Mechanisms of pulmonary fibrosis. Annu Rev Med 2004;55:395-417.
-
(2004)
Annu Rev Med
, vol.55
, pp. 395-417
-
-
Thannickal, V.J.1
Toews, G.B.2
White, E.S.3
Lynch III, J.P.4
Martinez, F.J.5
-
47
-
-
0033163392
-
Reactive oxygen and nitrogen intermediates increase transforming growth factor-beta1 release from human epithelial alveolar cells through two different mechanisms
-
Bellocq A, Azoulay E, Marullo S, Flahault A, Fouqueray B, Philippe C, Cadranel J, Baud L. Reactive oxygen and nitrogen intermediates increase transforming growth factor-beta1 release from human epithelial alveolar cells through two different mechanisms. Am J Respir Cell Mol Biol 1999;21:128-136.
-
(1999)
Am J Respir Cell Mol Biol
, vol.21
, pp. 128-136
-
-
Bellocq, A.1
Azoulay, E.2
Marullo, S.3
Flahault, A.4
Fouqueray, B.5
Philippe, C.6
Cadranel, J.7
Baud, L.8
-
48
-
-
0029736871
-
Redox-mediated activation of latent transforming growth factor-beta 1
-
Barcellos-Hoff MH, Dix TA. Redox-mediated activation of latent transforming growth factor-beta 1. Mol Endocrinol 1996;10:1077-1083.
-
(1996)
Mol Endocrinol
, vol.10
, pp. 1077-1083
-
-
Barcellos-Hoff, M.H.1
Dix, T.A.2
-
49
-
-
0029417335
-
Activation of an H2O2-generating NADH oxidase in human lung fibroblasts by transforming growth factor beta 1
-
Thannickal VJ, Fanburg BL. Activation of an H2O2-generating NADH oxidase in human lung fibroblasts by transforming growth factor beta 1. J Biol Chem 1995;270:30334-30338.
-
(1995)
J Biol Chem
, vol.270
, pp. 30334-30338
-
-
Thannickal, V.J.1
Fanburg, B.L.2
-
50
-
-
0031280268
-
Transforming growth factor-beta1 is a potent inhibitor of glutathione synthesis in the lung epithelial cell line A549: Transcriptional effect on the GSH rate-limiting enzyme gamma-glutamylcysteine synthetase
-
Arsalane K, Dubois CM, Muanza T, Begin R, Boudreau F, Asselin C, Cantin AM. Transforming growth factor-beta1 is a potent inhibitor of glutathione synthesis in the lung epithelial cell line A549: transcriptional effect on the GSH rate-limiting enzyme gamma-glutamylcysteine synthetase. Am J Respir Cell Mol Biol 1997;17:599-607.
-
(1997)
Am J Respir Cell Mol Biol
, vol.17
, pp. 599-607
-
-
Arsalane, K.1
Dubois, C.M.2
Muanza, T.3
Begin, R.4
Boudreau, F.5
Asselin, C.6
Cantin, A.M.7
-
51
-
-
0032546792
-
Disruption of redox homeostasis in the transforming growth factor-alpha/c-myc transgenic mouse model of accelerated hepatocarcinoaenesis
-
Factor VM, Kiss A, Woitach JT, Wirth PJ, Thorgeirsson SS. Disruption of redox homeostasis in the transforming growth factor-alpha/c-myc transgenic mouse model of accelerated hepatocarcinoaenesis. J Biol Chem 1998;273:15846-15853.
-
(1998)
J Biol Chem
, vol.273
, pp. 15846-15853
-
-
Factor, V.M.1
Kiss, A.2
Woitach, J.T.3
Wirth, P.J.4
Thorgeirsson, S.S.5
-
53
-
-
0036709597
-
Cellular glutathione and thiols metabolism
-
Dickinson DA, Forman HJ. Cellular glutathione and thiols metabolism. Biochem Pharmacol 2002;64:1019-1026.
-
(2002)
Biochem Pharmacol
, vol.64
, pp. 1019-1026
-
-
Dickinson, D.A.1
Forman, H.J.2
-
54
-
-
0034190372
-
Regulation of redox glutathione levels and gene transcription in lung inflammation: Therapeutic approaches
-
Rahman I, MacNee W. Regulation of redox glutathione levels and gene transcription in lung inflammation: therapeutic approaches. Free Radic Biol Med 2000;28:1405-1420.
-
(2000)
Free Radic Biol Med
, vol.28
, pp. 1405-1420
-
-
Rahman, I.1
MacNee, W.2
-
55
-
-
0033909952
-
Aerosolized administration of N-acetylcysteine attenuates lung fibrosis induced by bleomycin in mice
-
Hagiwara SI, Ishii Y, Kitamura S. Aerosolized administration of N-acetylcysteine attenuates lung fibrosis induced by bleomycin in mice. Am J Respir Crit Care Med 2000;162:225-231.
-
(2000)
Am J Respir Crit Care Med
, vol.162
, pp. 225-231
-
-
Hagiwara, S.I.1
Ishii, Y.2
Kitamura, S.3
-
56
-
-
0348013238
-
Oral N-acetylcysteine reduces bleomycin-induced lung damage and mucin Muc5ac expression in rats
-
Mata M, Ruiz A, Cerda M, Martinez-Losa M, Cortijo J, Santangelo F, Serrano-Mollar A, Llombart-Bosch A, Morcillo EJ. Oral N-acetylcysteine reduces bleomycin-induced lung damage and mucin Muc5ac expression in rats. Eur Respir J 2003;22:900-905.
-
(2003)
Eur Respir J
, vol.22
, pp. 900-905
-
-
Mata, M.1
Ruiz, A.2
Cerda, M.3
Martinez-Losa, M.4
Cortijo, J.5
Santangelo, F.6
Serrano-Mollar, A.7
Llombart-Bosch, A.8
Morcillo, E.J.9
-
57
-
-
0037361993
-
In vivo antioxidant treatment protects against bleomycin-induced lung damage in rats
-
Serrano-Mollar A, Closa D, Prats N, Blesa S, Martinez-Losa M, Cortijo J, Estrela JM, Morcillo EJ, Bulbena O. In vivo antioxidant treatment protects against bleomycin-induced lung damage in rats. Br J Pharmacol 2003;138:1037-1048.
-
(2003)
Br J Pharmacol
, vol.138
, pp. 1037-1048
-
-
Serrano-Mollar, A.1
Closa, D.2
Prats, N.3
Blesa, S.4
Martinez-Losa, M.5
Cortijo, J.6
Estrela, J.M.7
Morcillo, E.J.8
Bulbena, O.9
-
59
-
-
2942623947
-
Catalytic antioxidants: A radical approach to new therapeutics
-
Day BJ. Catalytic antioxidants: a radical approach to new therapeutics. Drug Discov Today 2004;9:557-566.
-
(2004)
Drug Discov Today
, vol.9
, pp. 557-566
-
-
Day, B.J.1
-
60
-
-
0034870839
-
Attenuation of bleomycin-induced pulmonary fibrosis by a catalytic antioxidant metalloporphyrin
-
Oury TD, Thakker K, Menache M, Chang LY, Crapo JD, Day BJ. Attenuation of bleomycin-induced pulmonary fibrosis by a catalytic antioxidant metalloporphyrin. Am J Respir Cell Mol Biol 2001;25:164-169.
-
(2001)
Am J Respir Cell Mol Biol
, vol.25
, pp. 164-169
-
-
Oury, T.D.1
Thakker, K.2
Menache, M.3
Chang, L.Y.4
Crapo, J.D.5
Day, B.J.6
-
61
-
-
0142196573
-
Enhanced bleomycin-induced pulmonary damage in mice lacking extracellular superoxide dismutase
-
Fattman CL, Chang LY, Termin TA, Petersen L, Enghild JJ, Oury TD. Enhanced bleomycin-induced pulmonary damage in mice lacking extracellular superoxide dismutase. Free Radic Biol Med 2003;35:763-771.
-
(2003)
Free Radic Biol Med
, vol.35
, pp. 763-771
-
-
Fattman, C.L.1
Chang, L.Y.2
Termin, T.A.3
Petersen, L.4
Enghild, J.J.5
Oury, T.D.6
-
63
-
-
2942713709
-
A small molecular weight catalytic metalloporphyrin antioxidant with superoxide dismutase (SOD) mimetic properties protects lungs from radiation-induced injury
-
Vujaskovic Z, Batinic-Haberle I, Rabbani ZN, Feng QF, Kang SK, Spasojevic I, Samulski TV, Fridovich I, Dewhirst MW, Anscher MS. A small molecular weight catalytic metalloporphyrin antioxidant with superoxide dismutase (SOD) mimetic properties protects lungs from radiation-induced injury. Free Radic Biol Med 2002;33:857-863.
-
(2002)
Free Radic Biol Med
, vol.33
, pp. 857-863
-
-
Vujaskovic, Z.1
Batinic-Haberle, I.2
Rabbani, Z.N.3
Feng, Q.F.4
Kang, S.K.5
Spasojevic, I.6
Samulski, T.V.7
Fridovich, I.8
Dewhirst, M.W.9
Anscher, M.S.10
-
64
-
-
0028230612
-
The effect of oral N-acetylcysteine on lung glutathione levels in idiopathic pulmonary fibrosis
-
Meyer A, Buhl R, Magnussen H. The effect of oral N-acetylcysteine on lung glutathione levels in idiopathic pulmonary fibrosis. Eur Respir J 1994;7:431-436.
-
(1994)
Eur Respir J
, vol.7
, pp. 431-436
-
-
Meyer, A.1
Buhl, R.2
Magnussen, H.3
-
65
-
-
0029093174
-
Intravenous N-acetylcysteine and lung glutathione of patients with pulmonary fibrosis and normals
-
Meyer A, Buhl R, Kampf S, Magnussen H. Intravenous N-acetylcysteine and lung glutathione of patients with pulmonary fibrosis and normals. Am J Respir Crit Care Med 1995;152:1055-1060.
-
(1995)
Am J Respir Crit Care Med
, vol.152
, pp. 1055-1060
-
-
Meyer, A.1
Buhl, R.2
Kampf, S.3
Magnussen, H.4
-
66
-
-
0031449645
-
Antioxidative and clinical effects of high-dose N-acetylcysteine in fibrosing alveolitis: Adjunctive therapy to maintenance immunosuppression
-
Behr J, Maier K, Degenkolb B, Krombach F, Vogelmeier C. Antioxidative and clinical effects of high-dose N-acetylcysteine in fibrosing alveolitis: adjunctive therapy to maintenance immunosuppression. Am J Respir Crit Care Med 1997;156:1897-1901.
-
(1997)
Am J Respir Crit Care Med
, vol.156
, pp. 1897-1901
-
-
Behr, J.1
Maier, K.2
Degenkolb, B.3
Krombach, F.4
Vogelmeier, C.5
-
67
-
-
7744226204
-
IFIGENIA: Effects of N-acetylcysteine (NAC) on primary end points VC and Dlco
-
Demedts M, Behr J, Buhl R, Convasce G, Costabel U, Dekhuijzen R, Jansen HM, Lankhorst I, Koyama A, MacNee W, et al. IFIGENIA: effects of N-acetylcysteine (NAC) on primary end points VC and Dlco [abstract]. Eur Respir J 2004;24:668s.
-
(2004)
Eur Respir J
, vol.24
-
-
Demedts, M.1
Behr, J.2
Buhl, R.3
Convasce, G.4
Costabel, U.5
Dekhuijzen, R.6
Jansen, H.M.7
Lankhorst, I.8
Koyama, A.9
MacNee, W.10
-
68
-
-
7744226204
-
IFIGENIA-study in IPF: Effects of N-acetylcysteine (NAC) on CRP, dyspnea, exercise test and HRCT
-
Demedts M, Behr J, Buhl R, Costabel U, Jansen HM, Thomeer M, Wallaert B, Lankhorst I, Sardina M, Corvasce G, et al. IFIGENIA-study in IPF: effects of N-acetylcysteine (NAC) on CRP, dyspnea, exercise test and HRCT [abstract]. Eur Respir J 2004;24:668s.
-
(2004)
Eur Respir J
, vol.24
-
-
Demedts, M.1
Behr, J.2
Buhl, R.3
Costabel, U.4
Jansen, H.M.5
Thomeer, M.6
Wallaert, B.7
Lankhorst, I.8
Sardina, M.9
Corvasce, G.10
|