메뉴 건너뛰기




Volumn 70, Issue 4, 2011, Pages 703-718

Integrating Physiological Regulation with Stem Cell and Tissue Homeostasis

Author keywords

[No Author keywords available]

Indexed keywords

OXYGEN;

EID: 79956199198     PISSN: 08966273     EISSN: 10974199     Source Type: Journal    
DOI: 10.1016/j.neuron.2011.05.011     Document Type: Review
Times cited : (66)

References (226)
  • 1
    • 43449084346 scopus 로고    scopus 로고
    • Long-term haematopoietic reconstitution by Trp53-/-p16Ink4a-/-p19Arf-/- multipotent progenitors
    • Akala O.O., Park I.K., Qian D., Pihalja M., Becker M.W., Clarke M.F. Long-term haematopoietic reconstitution by Trp53-/-p16Ink4a-/-p19Arf-/- multipotent progenitors. Nature 2008, 453:228-232.
    • (2008) Nature , vol.453 , pp. 228-232
    • Akala, O.O.1    Park, I.K.2    Qian, D.3    Pihalja, M.4    Becker, M.W.5    Clarke, M.F.6
  • 2
    • 0037480961 scopus 로고    scopus 로고
    • Telomerase is required to slow telomere shortening and extend replicative lifespan of HSCs during serial transplantation
    • Allsopp R.C., Morin G.B., DePinho R., Harley C.B., Weissman I.L. Telomerase is required to slow telomere shortening and extend replicative lifespan of HSCs during serial transplantation. Blood 2003, 102:517-520.
    • (2003) Blood , vol.102 , pp. 517-520
    • Allsopp, R.C.1    Morin, G.B.2    DePinho, R.3    Harley, C.B.4    Weissman, I.L.5
  • 3
    • 33749838643 scopus 로고    scopus 로고
    • Olfactory discrimination learning increases the survival of adult-born neurons in the olfactory bulb
    • Alonso M., Viollet C., Gabellec M.M., Meas-Yedid V., Olivo-Marin J.C., Lledo P.M. Olfactory discrimination learning increases the survival of adult-born neurons in the olfactory bulb. J. Neurosci. 2006, 26:10508-10513.
    • (2006) J. Neurosci. , vol.26 , pp. 10508-10513
    • Alonso, M.1    Viollet, C.2    Gabellec, M.M.3    Meas-Yedid, V.4    Olivo-Marin, J.C.5    Lledo, P.M.6
  • 4
    • 0036735672 scopus 로고    scopus 로고
    • Neuronal replacement from endogenous precursors in the adult brain after stroke
    • Arvidsson A., Collin T., Kirik D., Kokaia Z., Lindvall O. Neuronal replacement from endogenous precursors in the adult brain after stroke. Nat. Med. 2002, 8:963-970.
    • (2002) Nat. Med. , vol.8 , pp. 963-970
    • Arvidsson, A.1    Collin, T.2    Kirik, D.3    Kokaia, Z.4    Lindvall, O.5
  • 7
    • 13944278132 scopus 로고    scopus 로고
    • Mitochondria, oxidants, and aging
    • Balaban R.S., Nemoto S., Finkel T. Mitochondria, oxidants, and aging. Cell 2005, 120:483-495.
    • (2005) Cell , vol.120 , pp. 483-495
    • Balaban, R.S.1    Nemoto, S.2    Finkel, T.3
  • 8
    • 77953462161 scopus 로고    scopus 로고
    • Quiescent haematopoietic stem cells are activated by IFN-gamma in response to chronic infection
    • Baldridge M.T., King K.Y., Boles N.C., Weksberg D.C., Goodell M.A. Quiescent haematopoietic stem cells are activated by IFN-gamma in response to chronic infection. Nature 2010, 465:793-797.
    • (2010) Nature , vol.465 , pp. 793-797
    • Baldridge, M.T.1    King, K.Y.2    Boles, N.C.3    Weksberg, D.C.4    Goodell, M.A.5
  • 12
    • 78649687209 scopus 로고    scopus 로고
    • Circadian integration of metabolism and energetics
    • Bass J., Takahashi J.S. Circadian integration of metabolism and energetics. Science 2010, 330:1349-1354.
    • (2010) Science , vol.330 , pp. 1349-1354
    • Bass, J.1    Takahashi, J.S.2
  • 13
    • 35348972430 scopus 로고    scopus 로고
    • Genetic links between diet and lifespan: shared mechanisms from yeast to humans
    • Bishop N.A., Guarente L. Genetic links between diet and lifespan: shared mechanisms from yeast to humans. Nat. Rev. Genet. 2007, 8:835-844.
    • (2007) Nat. Rev. Genet. , vol.8 , pp. 835-844
    • Bishop, N.A.1    Guarente, L.2
  • 14
    • 69249122509 scopus 로고    scopus 로고
    • Exercise increases neural stem cell number in a growth hormone-dependent manner, augmenting the regenerative response in aged mice
    • Blackmore D.G., Golmohammadi M.G., Large B., Waters M.J., Rietze R.L. Exercise increases neural stem cell number in a growth hormone-dependent manner, augmenting the regenerative response in aged mice. Stem Cells 2009, 27:2044-2052.
    • (2009) Stem Cells , vol.27 , pp. 2044-2052
    • Blackmore, D.G.1    Golmohammadi, M.G.2    Large, B.3    Waters, M.J.4    Rietze, R.L.5
  • 16
    • 4444290010 scopus 로고    scopus 로고
    • Self-renewal, multipotency, and the existence of two cell populations within an epithelial stem cell niche
    • Blanpain C., Lowry W.E., Geoghegan A., Polak L., Fuchs E. Self-renewal, multipotency, and the existence of two cell populations within an epithelial stem cell niche. Cell 2004, 118:635-648.
    • (2004) Cell , vol.118 , pp. 635-648
    • Blanpain, C.1    Lowry, W.E.2    Geoghegan, A.3    Polak, L.4    Fuchs, E.5
  • 20
    • 1242271233 scopus 로고    scopus 로고
    • Impact of age and caloric restriction on neurogenesis in the dentate gyrus of C57BL/6 mice
    • Bondolfi L., Ermini F., Long J.M., Ingram D.K., Jucker M. Impact of age and caloric restriction on neurogenesis in the dentate gyrus of C57BL/6 mice. Neurobiol. Aging 2004, 25:333-340.
    • (2004) Neurobiol. Aging , vol.25 , pp. 333-340
    • Bondolfi, L.1    Ermini, F.2    Long, J.M.3    Ingram, D.K.4    Jucker, M.5
  • 21
    • 34848836428 scopus 로고    scopus 로고
    • Decline in self-renewal factors contributes to aging of the stem cell niche in the Drosophila testis
    • Boyle M., Wong C., Rocha M., Jones D.L. Decline in self-renewal factors contributes to aging of the stem cell niche in the Drosophila testis. Cell Stem Cell 2007, 1:470-478.
    • (2007) Cell Stem Cell , vol.1 , pp. 470-478
    • Boyle, M.1    Wong, C.2    Rocha, M.3    Jones, D.L.4
  • 22
    • 34547924424 scopus 로고    scopus 로고
    • Increased Wnt signaling during aging alters muscle stem cell fate and increases fibrosis
    • Brack A.S., Conboy M.J., Roy S., Lee M., Kuo C.J., Keller C., Rando T.A. Increased Wnt signaling during aging alters muscle stem cell fate and increases fibrosis. Science 2007, 317:807-810.
    • (2007) Science , vol.317 , pp. 807-810
    • Brack, A.S.1    Conboy, M.J.2    Roy, S.3    Lee, M.4    Kuo, C.J.5    Keller, C.6    Rando, T.A.7
  • 25
    • 30044434850 scopus 로고    scopus 로고
    • Microglia activated by IL-4 or IFN-gamma differentially induce neurogenesis and oligodendrogenesis from adult stem/progenitor cells
    • Butovsky O., Ziv Y., Schwartz A., Landa G., Talpalar A.E., Pluchino S., Martino G., Schwartz M. Microglia activated by IL-4 or IFN-gamma differentially induce neurogenesis and oligodendrogenesis from adult stem/progenitor cells. Mol. Cell. Neurosci. 2006, 31:149-160.
    • (2006) Mol. Cell. Neurosci. , vol.31 , pp. 149-160
    • Butovsky, O.1    Ziv, Y.2    Schwartz, A.3    Landa, G.4    Talpalar, A.E.5    Pluchino, S.6    Martino, G.7    Schwartz, M.8
  • 26
    • 47949097215 scopus 로고    scopus 로고
    • Imbalance between pSmad3 and Notch induces CDK inhibitors in old muscle stem cells
    • Carlson M.E., Hsu M., Conboy I.M. Imbalance between pSmad3 and Notch induces CDK inhibitors in old muscle stem cells. Nature 2008, 454:528-532.
    • (2008) Nature , vol.454 , pp. 528-532
    • Carlson, M.E.1    Hsu, M.2    Conboy, I.M.3
  • 27
    • 18144446836 scopus 로고    scopus 로고
    • Circulating insulin-like growth factor I mediates effects of exercise on the brain
    • Carro E., Nuñez A., Busiguina S., Torres-Aleman I. Circulating insulin-like growth factor I mediates effects of exercise on the brain. J. Neurosci. 2000, 20:2926-2933.
    • (2000) J. Neurosci. , vol.20 , pp. 2926-2933
    • Carro, E.1    Nuñez, A.2    Busiguina, S.3    Torres-Aleman, I.4
  • 28
    • 33745274726 scopus 로고    scopus 로고
    • Mitochondria: dynamic organelles in disease, aging, and development
    • Chan D.C. Mitochondria: dynamic organelles in disease, aging, and development. Cell 2006, 125:1241-1252.
    • (2006) Cell , vol.125 , pp. 1241-1252
    • Chan, D.C.1
  • 29
    • 78650503295 scopus 로고    scopus 로고
    • Nutrition-responsive glia control exit of neural stem cells from quiescence
    • Chell J.M., Brand A.H. Nutrition-responsive glia control exit of neural stem cells from quiescence. Cell 2010, 143:1161-1173.
    • (2010) Cell , vol.143 , pp. 1161-1173
    • Chell, J.M.1    Brand, A.H.2
  • 30
    • 53349091768 scopus 로고    scopus 로고
    • TSC-mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species
    • Chen C., Liu Y., Liu R., Ikenoue T., Guan K.L., Liu Y., Zheng P. TSC-mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species. J. Exp. Med. 2008, 205:2397-2408.
    • (2008) J. Exp. Med. , vol.205 , pp. 2397-2408
    • Chen, C.1    Liu, Y.2    Liu, R.3    Ikenoue, T.4    Guan, K.L.5    Liu, Y.6    Zheng, P.7
  • 31
    • 0033694302 scopus 로고    scopus 로고
    • Stem cell repopulation efficiency but not pool size is governed by p27(kip1)
    • Cheng T., Rodrigues N., Dombkowski D., Stier S., Scadden D.T. Stem cell repopulation efficiency but not pool size is governed by p27(kip1). Nat. Med. 2000, 6:1235-1240.
    • (2000) Nat. Med. , vol.6 , pp. 1235-1240
    • Cheng, T.1    Rodrigues, N.2    Dombkowski, D.3    Stier, S.4    Scadden, D.T.5
  • 33
    • 36249023751 scopus 로고    scopus 로고
    • The effect of bleeding on hematopoietic stem cell cycling and self-renewal
    • Cheshier S.H., Prohaska S.S., Weissman I.L. The effect of bleeding on hematopoietic stem cell cycling and self-renewal. Stem Cells Dev. 2007, 16:707-717.
    • (2007) Stem Cells Dev. , vol.16 , pp. 707-717
    • Cheshier, S.H.1    Prohaska, S.S.2    Weissman, I.L.3
  • 35
    • 77957551487 scopus 로고    scopus 로고
    • Prdm16 promotes stem cell maintenance in multiple tissues, partly by regulating oxidative stress
    • Chuikov S., Levi B.P., Smith M.L., Morrison S.J. Prdm16 promotes stem cell maintenance in multiple tissues, partly by regulating oxidative stress. Nat. Cell Biol. 2010, 12:999-1006.
    • (2010) Nat. Cell Biol. , vol.12 , pp. 999-1006
    • Chuikov, S.1    Levi, B.P.2    Smith, M.L.3    Morrison, S.J.4
  • 36
    • 0035945656 scopus 로고    scopus 로고
    • Estrogen and the risk of breast cancer
    • Clemons M., Goss P. Estrogen and the risk of breast cancer. N. Engl. J. Med. 2001, 344:276-285.
    • (2001) N. Engl. J. Med. , vol.344 , pp. 276-285
    • Clemons, M.1    Goss, P.2
  • 37
    • 0344827208 scopus 로고    scopus 로고
    • Notch-mediated restoration of regenerative potential to aged muscle
    • Conboy I.M., Conboy M.J., Smythe G.M., Rando T.A. Notch-mediated restoration of regenerative potential to aged muscle. Science 2003, 302:1575-1577.
    • (2003) Science , vol.302 , pp. 1575-1577
    • Conboy, I.M.1    Conboy, M.J.2    Smythe, G.M.3    Rando, T.A.4
  • 38
    • 13944261231 scopus 로고    scopus 로고
    • Rejuvenation of aged progenitor cells by exposure to a young systemic environment
    • Conboy I.M., Conboy M.J., Wagers A.J., Girma E.R., Weissman I.L., Rando T.A. Rejuvenation of aged progenitor cells by exposure to a young systemic environment. Nature 2005, 433:760-764.
    • (2005) Nature , vol.433 , pp. 760-764
    • Conboy, I.M.1    Conboy, M.J.2    Wagers, A.J.3    Girma, E.R.4    Weissman, I.L.5    Rando, T.A.6
  • 40
    • 0025313294 scopus 로고
    • Label-retaining cells reside in the bulge area of pilosebaceous unit: implications for follicular stem cells, hair cycle, and skin carcinogenesis
    • Cotsarelis G., Sun T.T., Lavker R.M. Label-retaining cells reside in the bulge area of pilosebaceous unit: implications for follicular stem cells, hair cycle, and skin carcinogenesis. Cell 1990, 61:1329-1337.
    • (1990) Cell , vol.61 , pp. 1329-1337
    • Cotsarelis, G.1    Sun, T.T.2    Lavker, R.M.3
  • 42
    • 0031028973 scopus 로고    scopus 로고
    • Mouse strain-dependent changes in frequency and proliferation of hematopoietic stem cells during aging: correlation between lifespan and cycling activity
    • de Haan G., Nijhof W., Van Zant G. Mouse strain-dependent changes in frequency and proliferation of hematopoietic stem cells during aging: correlation between lifespan and cycling activity. Blood 1997, 89:1543-1550.
    • (1997) Blood , vol.89 , pp. 1543-1550
    • de Haan, G.1    Nijhof, W.2    Van Zant, G.3
  • 43
    • 37449024702 scopus 로고    scopus 로고
    • The biology of cancer: metabolic reprogramming fuels cell growth and proliferation
    • DeBerardinis R.J., Lum J.J., Hatzivassiliou G., Thompson C.B. The biology of cancer: metabolic reprogramming fuels cell growth and proliferation. Cell Metab. 2008, 7:11-20.
    • (2008) Cell Metab. , vol.7 , pp. 11-20
    • DeBerardinis, R.J.1    Lum, J.J.2    Hatzivassiliou, G.3    Thompson, C.B.4
  • 45
    • 0141785164 scopus 로고    scopus 로고
    • A niche for adult neural stem cells
    • Doetsch F. A niche for adult neural stem cells. Curr. Opin. Genet. Dev. 2003, 13:543-550.
    • (2003) Curr. Opin. Genet. Dev. , vol.13 , pp. 543-550
    • Doetsch, F.1
  • 46
    • 0033040497 scopus 로고    scopus 로고
    • Subventricular zone astrocytes are neural stem cells in the adult mammalian brain
    • Doetsch F., Caillé I., Lim D.A., García-Verdugo J.M., Alvarez-Buylla A. Subventricular zone astrocytes are neural stem cells in the adult mammalian brain. Cell 1999, 97:703-716.
    • (1999) Cell , vol.97 , pp. 703-716
    • Doetsch, F.1    Caillé, I.2    Lim, D.A.3    García-Verdugo, J.M.4    Alvarez-Buylla, A.5
  • 47
    • 0037088913 scopus 로고    scopus 로고
    • Lack of the cell-cycle inhibitor p27Kip1 results in selective increase of transit-amplifying cells for adult neurogenesis
    • Doetsch F., Verdugo J.M., Caille I., Alvarez-Buylla A., Chao M.V., Casaccia-Bonnefil P. Lack of the cell-cycle inhibitor p27Kip1 results in selective increase of transit-amplifying cells for adult neurogenesis. J. Neurosci. 2002, 22:2255-2264.
    • (2002) J. Neurosci. , vol.22 , pp. 2255-2264
    • Doetsch, F.1    Verdugo, J.M.2    Caille, I.3    Alvarez-Buylla, A.4    Chao, M.V.5    Casaccia-Bonnefil, P.6
  • 48
    • 0038118780 scopus 로고    scopus 로고
    • Acute leukemia: a pediatric perspective
    • Downing J.R., Shannon K.M. Acute leukemia: a pediatric perspective. Cancer Cell 2002, 2:437-445.
    • (2002) Cancer Cell , vol.2 , pp. 437-445
    • Downing, J.R.1    Shannon, K.M.2
  • 49
    • 0035281979 scopus 로고    scopus 로고
    • Stem cells and their progeny respond to nutritional changes during Drosophila oogenesis
    • Drummond-Barbosa D., Spradling A.C. Stem cells and their progeny respond to nutritional changes during Drosophila oogenesis. Dev. Biol. 2001, 231:265-278.
    • (2001) Dev. Biol. , vol.231 , pp. 265-278
    • Drummond-Barbosa, D.1    Spradling, A.C.2
  • 51
  • 52
    • 33746257209 scopus 로고    scopus 로고
    • The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism
    • Engelman J.A., Luo J., Cantley L.C. The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism. Nat. Rev. Genet. 2006, 7:606-619.
    • (2006) Nat. Rev. Genet. , vol.7 , pp. 606-619
    • Engelman, J.A.1    Luo, J.2    Cantley, L.C.3
  • 53
    • 38949159709 scopus 로고    scopus 로고
    • Effects of dietary restriction on hematopoietic stem-cell aging are genetically regulated
    • Ertl R.P., Chen J., Astle C.M., Duffy T.M., Harrison D.E. Effects of dietary restriction on hematopoietic stem-cell aging are genetically regulated. Blood 2008, 111:1709-1716.
    • (2008) Blood , vol.111 , pp. 1709-1716
    • Ertl, R.P.1    Chen, J.2    Astle, C.M.3    Duffy, T.M.4    Harrison, D.E.5
  • 55
    • 70349592516 scopus 로고    scopus 로고
    • The relationship between pluripotency and mitochondrial DNA proliferation during early embryo development and embryonic stem cell differentiation
    • Facucho-Oliveira J.M., St John J.C. The relationship between pluripotency and mitochondrial DNA proliferation during early embryo development and embryonic stem cell differentiation. Stem Cell Rev. 2009, 5:140-158.
    • (2009) Stem Cell Rev. , vol.5 , pp. 140-158
    • Facucho-Oliveira, J.M.1    St John, J.C.2
  • 57
    • 4544256099 scopus 로고    scopus 로고
    • Telomere shortening and chromosomal instability abrogates proliferation of adult but not embryonic neural stem cells
    • Ferrón S., Mira H., Franco S., Cano-Jaimez M., Bellmunt E., Ramírez C., Fariñas I., Blasco M.A. Telomere shortening and chromosomal instability abrogates proliferation of adult but not embryonic neural stem cells. Development 2004, 131:4059-4070.
    • (2004) Development , vol.131 , pp. 4059-4070
    • Ferrón, S.1    Mira, H.2    Franco, S.3    Cano-Jaimez, M.4    Bellmunt, E.5    Ramírez, C.6    Fariñas, I.7    Blasco, M.A.8
  • 58
    • 23844540299 scopus 로고    scopus 로고
    • Effects of telomerase and telomere length on epidermal stem cell behavior
    • Flores I., Cayuela M.L., Blasco M.A. Effects of telomerase and telomere length on epidermal stem cell behavior. Science 2005, 309:1253-1256.
    • (2005) Science , vol.309 , pp. 1253-1256
    • Flores, I.1    Cayuela, M.L.2    Blasco, M.A.3
  • 60
    • 0014342920 scopus 로고
    • Erythropoiesis in the spleen and bone marrow of the pregnant mouse
    • Fowler J.H., Nash D.J. Erythropoiesis in the spleen and bone marrow of the pregnant mouse. Dev. Biol. 1968, 18:331-353.
    • (1968) Dev. Biol. , vol.18 , pp. 331-353
    • Fowler, J.H.1    Nash, D.J.2
  • 61
    • 34247527731 scopus 로고    scopus 로고
    • Male and female Drosophila germline stem cells: two versions of immortality
    • Fuller M.T., Spradling A.C. Male and female Drosophila germline stem cells: two versions of immortality. Science 2007, 316:402-404.
    • (2007) Science , vol.316 , pp. 402-404
    • Fuller, M.T.1    Spradling, A.C.2
  • 66
    • 0041880122 scopus 로고    scopus 로고
    • SOX2 functions to maintain neural progenitor identity
    • Graham V., Khudyakov J., Ellis P., Pevny L. SOX2 functions to maintain neural progenitor identity. Neuron 2003, 39:749-765.
    • (2003) Neuron , vol.39 , pp. 749-765
    • Graham, V.1    Khudyakov, J.2    Ellis, P.3    Pevny, L.4
  • 72
    • 34447523379 scopus 로고    scopus 로고
    • Cell proliferation in the dentate gyrus of the adult rat fluctuates with the light-dark cycle
    • Guzman-Marin R., Suntsova N., Bashir T., Szymusiak R., Mcginty D. Cell proliferation in the dentate gyrus of the adult rat fluctuates with the light-dark cycle. Neurosci. Lett. 2007, 422:198-201.
    • (2007) Neurosci. Lett. , vol.422 , pp. 198-201
    • Guzman-Marin, R.1    Suntsova, N.2    Bashir, T.3    Szymusiak, R.4    Mcginty, D.5
  • 73
    • 33747596652 scopus 로고    scopus 로고
    • Oxygen sensing by mitochondria at complex III: the paradox of increased reactive oxygen species during hypoxia
    • Guzy R.D., Schumacker P.T. Oxygen sensing by mitochondria at complex III: the paradox of increased reactive oxygen species during hypoxia. Exp. Physiol. 2006, 91:807-819.
    • (2006) Exp. Physiol. , vol.91 , pp. 807-819
    • Guzy, R.D.1    Schumacker, P.T.2
  • 75
    • 0025992197 scopus 로고
    • Most primitive hematopoietic stem cells are stimulated to cycle rapidly after treatment with 5-fluorouracil
    • Harrison D.E., Lerner C.P. Most primitive hematopoietic stem cells are stimulated to cycle rapidly after treatment with 5-fluorouracil. Blood 1991, 78:1237-1240.
    • (1991) Blood , vol.78 , pp. 1237-1240
    • Harrison, D.E.1    Lerner, C.P.2
  • 79
    • 37349069492 scopus 로고    scopus 로고
    • Be smart, exercise your heart: exercise effects on brain and cognition
    • Hillman C.H., Erickson K.I., Kramer A.F. Be smart, exercise your heart: exercise effects on brain and cognition. Nat. Rev. Neurosci. 2008, 9:58-65.
    • (2008) Nat. Rev. Neurosci. , vol.9 , pp. 58-65
    • Hillman, C.H.1    Erickson, K.I.2    Kramer, A.F.3
  • 82
    • 59049103731 scopus 로고    scopus 로고
    • Insulin levels control female germline stem cell maintenance via the niche in Drosophila
    • Hsu H.J., Drummond-Barbosa D. Insulin levels control female germline stem cell maintenance via the niche in Drosophila. Proc. Natl. Acad. Sci. USA 2009, 106:1117-1121.
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 1117-1121
    • Hsu, H.J.1    Drummond-Barbosa, D.2
  • 83
    • 77955273858 scopus 로고    scopus 로고
    • Mitochondrial respiration defects modulate differentiation but not proliferation of hematopoietic stem and progenitor cells
    • Inoue S., Noda S., Kashima K., Nakada K., Hayashi J., Miyoshi H. Mitochondrial respiration defects modulate differentiation but not proliferation of hematopoietic stem and progenitor cells. FEBS Lett. 2010, 584:3402-3409.
    • (2010) FEBS Lett. , vol.584 , pp. 3402-3409
    • Inoue, S.1    Noda, S.2    Kashima, K.3    Nakada, K.4    Hayashi, J.5    Miyoshi, H.6
  • 85
    • 0033552813 scopus 로고    scopus 로고
    • The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus
    • Jacobs J.J.L., Kieboom K., Marino S., DePinho R.A., van Lohuizen M. The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus. Nature 1999, 397:164-168.
    • (1999) Nature , vol.397 , pp. 164-168
    • Jacobs, J.J.L.1    Kieboom, K.2    Marino, S.3    DePinho, R.A.4    van Lohuizen, M.5
  • 86
    • 39149130361 scopus 로고    scopus 로고
    • Stem cells, the molecular circuitry of pluripotency and nuclear reprogramming
    • Jaenisch R., Young R. Stem cells, the molecular circuitry of pluripotency and nuclear reprogramming. Cell 2008, 132:567-582.
    • (2008) Cell , vol.132 , pp. 567-582
    • Jaenisch, R.1    Young, R.2
  • 90
    • 0028958031 scopus 로고
    • Insulin-like growth factors and their binding proteins: biological actions
    • Jones J.I., Clemmons D.R. Insulin-like growth factors and their binding proteins: biological actions. Endocr. Rev. 1995, 16:3-34.
    • (1995) Endocr. Rev. , vol.16 , pp. 3-34
    • Jones, J.I.1    Clemmons, D.R.2
  • 92
    • 34548462072 scopus 로고    scopus 로고
    • Unique and independent roles for MLL in adult hematopoietic stem cells and progenitors
    • Jude C.D., Climer L., Xu D., Artinger E., Fisher J.K., Ernst P. Unique and independent roles for MLL in adult hematopoietic stem cells and progenitors. Cell Stem Cell 2007, 1:324-337.
    • (2007) Cell Stem Cell , vol.1 , pp. 324-337
    • Jude, C.D.1    Climer, L.2    Xu, D.3    Artinger, E.4    Fisher, J.K.5    Ernst, P.6
  • 93
    • 77953283847 scopus 로고    scopus 로고
    • AKT1 and AKT2 maintain hematopoietic stem cell function by regulating reactive oxygen species
    • Juntilla M.M., Patil V.D., Calamito M., Joshi R.P., Birnbaum M.J., Koretzky G.A. AKT1 and AKT2 maintain hematopoietic stem cell function by regulating reactive oxygen species. Blood 2010, 115:4030-4038.
    • (2010) Blood , vol.115 , pp. 4030-4038
    • Juntilla, M.M.1    Patil, V.D.2    Calamito, M.3    Joshi, R.P.4    Birnbaum, M.J.5    Koretzky, G.A.6
  • 94
    • 31044450303 scopus 로고    scopus 로고
    • Signals from the sympathetic nervous system regulate hematopoietic stem cell egress from bone marrow
    • Katayama Y., Battista M., Kao W.M., Hidalgo A., Peired A.J., Thomas S.A., Frenette P.S. Signals from the sympathetic nervous system regulate hematopoietic stem cell egress from bone marrow. Cell 2006, 124:407-421.
    • (2006) Cell , vol.124 , pp. 407-421
    • Katayama, Y.1    Battista, M.2    Kao, W.M.3    Hidalgo, A.4    Peired, A.J.5    Thomas, S.A.6    Frenette, P.S.7
  • 96
    • 21244463426 scopus 로고    scopus 로고
    • SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells
    • Kiel M.J., Yilmaz O.H., Iwashita T., Yilmaz O.H., Terhorst C., Morrison S.J. SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells. Cell 2005, 121:1109-1121.
    • (2005) Cell , vol.121 , pp. 1109-1121
    • Kiel, M.J.1    Yilmaz, O.H.2    Iwashita, T.3    Yilmaz, O.H.4    Terhorst, C.5    Morrison, S.J.6
  • 98
    • 0032100452 scopus 로고    scopus 로고
    • Rhodamine-123 staining in hematopoietic stem cells of young mice indicates mitochondrial activation rather than dye efflux
    • Kim M., Cooper D.D., Hayes S.F., Spangrude G.J. Rhodamine-123 staining in hematopoietic stem cells of young mice indicates mitochondrial activation rather than dye efflux. Blood 1998, 91:4106-4117.
    • (1998) Blood , vol.91 , pp. 4106-4117
    • Kim, M.1    Cooper, D.D.2    Hayes, S.F.3    Spangrude, G.J.4
  • 99
    • 0037431083 scopus 로고    scopus 로고
    • SOX10 maintains multipotency and inhibits neuronal differentiation of neural crest stem cells
    • Kim J., Lo L., Dormand E., Anderson D.J. SOX10 maintains multipotency and inhibits neuronal differentiation of neural crest stem cells. Neuron 2003, 38:17-31.
    • (2003) Neuron , vol.38 , pp. 17-31
    • Kim, J.1    Lo, L.2    Dormand, E.3    Anderson, D.J.4
  • 100
    • 34547668398 scopus 로고    scopus 로고
    • Sox17 dependence distinguishes the transcriptional regulation of fetal from adult hematopoietic stem cells
    • Kim I., Saunders T.L., Morrison S.J. Sox17 dependence distinguishes the transcriptional regulation of fetal from adult hematopoietic stem cells. Cell 2007, 130:470-483.
    • (2007) Cell , vol.130 , pp. 470-483
    • Kim, I.1    Saunders, T.L.2    Morrison, S.J.3
  • 102
    • 36849045088 scopus 로고    scopus 로고
    • Controls of germline stem cells, entry into meiosis, and the sperm/oocyte decision in Caenorhabditis elegans
    • Kimble J., Crittenden S.L. Controls of germline stem cells, entry into meiosis, and the sperm/oocyte decision in Caenorhabditis elegans. Annu. Rev. Cell Dev. Biol. 2007, 23:405-433.
    • (2007) Annu. Rev. Cell Dev. Biol. , vol.23 , pp. 405-433
    • Kimble, J.1    Crittenden, S.L.2
  • 103
    • 15444377643 scopus 로고    scopus 로고
    • P21 loss compromises the relative quiescence of forebrain stem cell proliferation leading to exhaustion of their proliferation capacity
    • Kippin T.E., Martens D.J., van der Kooy D. p21 loss compromises the relative quiescence of forebrain stem cell proliferation leading to exhaustion of their proliferation capacity. Genes Dev. 2005, 19:756-767.
    • (2005) Genes Dev. , vol.19 , pp. 756-767
    • Kippin, T.E.1    Martens, D.J.2    van der Kooy, D.3
  • 104
    • 34547145922 scopus 로고    scopus 로고
    • Loss of a quiescent niche but not follicle stem cells in the absence of bone morphogenetic protein signaling
    • Kobielak K., Stokes N., de la Cruz J., Polak L., Fuchs E. Loss of a quiescent niche but not follicle stem cells in the absence of bone morphogenetic protein signaling. Proc. Natl. Acad. Sci. USA 2007, 104:10063-10068.
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 10063-10068
    • Kobielak, K.1    Stokes, N.2    de la Cruz, J.3    Polak, L.4    Fuchs, E.5
  • 107
    • 70350591064 scopus 로고    scopus 로고
    • Interactive effect of excitotoxic injury and dietary restriction on neurogenesis and neurotrophic factors in adult male rat brain
    • Kumar S., Parkash J., Kataria H., Kaur G. Interactive effect of excitotoxic injury and dietary restriction on neurogenesis and neurotrophic factors in adult male rat brain. Neurosci. Res. 2009, 65:367-374.
    • (2009) Neurosci. Res. , vol.65 , pp. 367-374
    • Kumar, S.1    Parkash, J.2    Kataria, H.3    Kaur, G.4
  • 108
    • 23644444460 scopus 로고    scopus 로고
    • Direct control of germline stem cell division and cyst growth by neural insulin in Drosophila
    • LaFever L., Drummond-Barbosa D. Direct control of germline stem cell division and cyst growth by neural insulin in Drosophila. Science 2005, 309:1071-1073.
    • (2005) Science , vol.309 , pp. 1071-1073
    • LaFever, L.1    Drummond-Barbosa, D.2
  • 109
    • 78650968492 scopus 로고    scopus 로고
    • Proliferative neural stem cells have high endogenous ROS levels that regulate self-renewal and neurogenesis in a PI3K/Akt-dependant manner
    • Le Belle J.E., Orozco N.M., Paucar A.A., Saxe J.P., Mottahedeh J., Pyle A.D., Wu H., Kornblum H.I. Proliferative neural stem cells have high endogenous ROS levels that regulate self-renewal and neurogenesis in a PI3K/Akt-dependant manner. Cell Stem Cell 2011, 8:59-71.
    • (2011) Cell Stem Cell , vol.8 , pp. 59-71
    • Le Belle, J.E.1    Orozco, N.M.2    Paucar, A.A.3    Saxe, J.P.4    Mottahedeh, J.5    Pyle, A.D.6    Wu, H.7    Kornblum, H.I.8
  • 110
    • 24644494270 scopus 로고    scopus 로고
    • Asymmetric cell divisions promote stratification and differentiation of mammalian skin
    • Lechler T., Fuchs E. Asymmetric cell divisions promote stratification and differentiation of mammalian skin. Nature 2005, 437:275-280.
    • (2005) Nature , vol.437 , pp. 275-280
    • Lechler, T.1    Fuchs, E.2
  • 112
    • 0036488190 scopus 로고    scopus 로고
    • Dietary restriction enhances neurotrophin expression and neurogenesis in the hippocampus of adult mice
    • Lee J., Seroogy K.B., Mattson M.P. Dietary restriction enhances neurotrophin expression and neurogenesis in the hippocampus of adult mice. J. Neurochem. 2002, 80:539-547.
    • (2002) J. Neurochem. , vol.80 , pp. 539-547
    • Lee, J.1    Seroogy, K.B.2    Mattson, M.P.3
  • 114
    • 78049496814 scopus 로고    scopus 로고
    • MTOR activation induces tumor suppressors that inhibit leukemogenesis and deplete hematopoietic stem cells after Pten deletion
    • Lee J.Y., Nakada D., Yilmaz O.H., Tothova Z., Joseph N.M., Lim M.S., Gilliland D.G., Morrison S.J. mTOR activation induces tumor suppressors that inhibit leukemogenesis and deplete hematopoietic stem cells after Pten deletion. Cell Stem Cell 2010, 7:593-605.
    • (2010) Cell Stem Cell , vol.7 , pp. 593-605
    • Lee, J.Y.1    Nakada, D.2    Yilmaz, O.H.3    Tothova, Z.4    Joseph, N.M.5    Lim, M.S.6    Gilliland, D.G.7    Morrison, S.J.8
  • 116
    • 0037673984 scopus 로고    scopus 로고
    • Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells
    • Lessard J., Sauvageau G. Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells. Nature 2003, 423:255-260.
    • (2003) Nature , vol.423 , pp. 255-260
    • Lessard, J.1    Sauvageau, G.2
  • 118
    • 66449121507 scopus 로고    scopus 로고
    • Stem cells use distinct self-renewal programs at different ages
    • Levi B.P., Morrison S.J. Stem cells use distinct self-renewal programs at different ages. Cold Spring Harb. Symp. Quant. Biol. 2008, 73:539-553.
    • (2008) Cold Spring Harb. Symp. Quant. Biol. , vol.73 , pp. 539-553
    • Levi, B.P.1    Morrison, S.J.2
  • 119
    • 0023678904 scopus 로고
    • Circadian and seasonal rhythms in murine bone marrow colony-forming cells affect tolerance for the anticancer agent 4'-O-tetrahydropyranyladriamycin (THP)
    • Lévi F., Blazsek I., Ferlé-Vidovic A. Circadian and seasonal rhythms in murine bone marrow colony-forming cells affect tolerance for the anticancer agent 4'-O-tetrahydropyranyladriamycin (THP). Exp. Hematol. 1988, 16:696-701.
    • (1988) Exp. Hematol. , vol.16 , pp. 696-701
    • Lévi, F.1    Blazsek, I.2    Ferlé-Vidovic, A.3
  • 121
    • 77954509661 scopus 로고    scopus 로고
    • Endogenous interferon gamma directly regulates neural precursors in the non-inflammatory brain
    • Li L., Walker T.L., Zhang Y., Mackay E.W., Bartlett P.F. Endogenous interferon gamma directly regulates neural precursors in the non-inflammatory brain. J. Neurosci. 2010, 30:9038-9050.
    • (2010) J. Neurosci. , vol.30 , pp. 9038-9050
    • Li, L.1    Walker, T.L.2    Zhang, Y.3    Mackay, E.W.4    Bartlett, P.F.5
  • 122
    • 78650225862 scopus 로고    scopus 로고
    • Regulation of bone marrow hematopoietic stem cell is involved in high-altitude erythrocytosis
    • Li P., Huang J., Tian H.J., Huang Q.Y., Jiang C.H., Gao Y.Q. Regulation of bone marrow hematopoietic stem cell is involved in high-altitude erythrocytosis. Exp. Hematol. 2011, 39:37-46.
    • (2011) Exp. Hematol. , vol.39 , pp. 37-46
    • Li, P.1    Huang, J.2    Tian, H.J.3    Huang, Q.Y.4    Jiang, C.H.5    Gao, Y.Q.6
  • 127
    • 52949116088 scopus 로고    scopus 로고
    • Mobilized hematopoietic stem cell yield depends on species-specific circadian timing
    • Lucas D., Battista M., Shi P.A., Isola L., Frenette P.S. Mobilized hematopoietic stem cell yield depends on species-specific circadian timing. Cell Stem Cell 2008, 3:364-366.
    • (2008) Cell Stem Cell , vol.3 , pp. 364-366
    • Lucas, D.1    Battista, M.2    Shi, P.A.3    Isola, L.4    Frenette, P.S.5
  • 128
    • 77955368742 scopus 로고    scopus 로고
    • Quiescent and active hippocampal neural stem cells with distinct morphologies respond selectively to physiological and pathological stimuli and aging
    • Lugert S., Basak O., Knuckles P., Haussler U., Fabel K., Götz M., Haas C.A., Kempermann G., Taylor V., Giachino C. Quiescent and active hippocampal neural stem cells with distinct morphologies respond selectively to physiological and pathological stimuli and aging. Cell Stem Cell 2010, 6:445-456.
    • (2010) Cell Stem Cell , vol.6 , pp. 445-456
    • Lugert, S.1    Basak, O.2    Knuckles, P.3    Haussler, U.4    Fabel, K.5    Götz, M.6    Haas, C.A.7    Kempermann, G.8    Taylor, V.9    Giachino, C.10
  • 129
    • 78349276172 scopus 로고    scopus 로고
    • Dietary restriction enhances germline stem cell maintenance
    • Mair W., Mcleod C.J., Wang L., Jones D.L. Dietary restriction enhances germline stem cell maintenance. Aging Cell 2010, 9:916-918.
    • (2010) Aging Cell , vol.9 , pp. 916-918
    • Mair, W.1    Mcleod, C.J.2    Wang, L.3    Jones, D.L.4
  • 130
    • 78649364332 scopus 로고    scopus 로고
    • Hypoxia-inducible factors and the response to hypoxic stress
    • Majmundar A.J., Wong W.J., Simon M.C. Hypoxia-inducible factors and the response to hypoxic stress. Mol. Cell 2010, 40:294-309.
    • (2010) Mol. Cell , vol.40 , pp. 294-309
    • Majmundar, A.J.1    Wong, W.J.2    Simon, M.C.3
  • 131
  • 133
    • 1242341960 scopus 로고    scopus 로고
    • Neural stem cell detection, characterization, and age-related changes in the subventricular zone of mice
    • Maslov A.Y., Barone T.A., Plunkett R.J., Pruitt S.C. Neural stem cell detection, characterization, and age-related changes in the subventricular zone of mice. J. Neurosci. 2004, 24:1726-1733.
    • (2004) J. Neurosci. , vol.24 , pp. 1726-1733
    • Maslov, A.Y.1    Barone, T.A.2    Plunkett, R.J.3    Pruitt, S.C.4
  • 136
    • 78650175195 scopus 로고    scopus 로고
    • Stem cell dynamics in response to nutrient availability
    • Mcleod C.J., Wang L., Wong C., Jones D.L. Stem cell dynamics in response to nutrient availability. Curr. Biol. 2010, 20:2100-2105.
    • (2010) Curr. Biol. , vol.20 , pp. 2100-2105
    • Mcleod, C.J.1    Wang, L.2    Wong, C.3    Jones, D.L.4
  • 138
    • 39749164920 scopus 로고    scopus 로고
    • Haematopoietic stem cell release is regulated by circadian oscillations
    • Méndez-Ferrer S., Lucas D., Battista M., Frenette P.S. Haematopoietic stem cell release is regulated by circadian oscillations. Nature 2008, 452:442-447.
    • (2008) Nature , vol.452 , pp. 442-447
    • Méndez-Ferrer, S.1    Lucas, D.2    Battista, M.3    Frenette, P.S.4
  • 141
    • 50849113768 scopus 로고    scopus 로고
    • Neural stem cells confer unique pinwheel architecture to the ventricular surface in neurogenic regions of the adult brain
    • Mirzadeh Z., Merkle F.T., Soriano-Navarro M., Garcia-Verdugo J.M., Alvarez-Buylla A. Neural stem cells confer unique pinwheel architecture to the ventricular surface in neurogenic regions of the adult brain. Cell Stem Cell 2008, 3:265-278.
    • (2008) Cell Stem Cell , vol.3 , pp. 265-278
    • Mirzadeh, Z.1    Merkle, F.T.2    Soriano-Navarro, M.3    Garcia-Verdugo, J.M.4    Alvarez-Buylla, A.5
  • 144
    • 77956224494 scopus 로고    scopus 로고
    • Oxygen in stem cell biology: a critical component of the stem cell niche
    • Mohyeldin A., Garzón-Muvdi T., Quiñones-Hinojosa A. Oxygen in stem cell biology: a critical component of the stem cell niche. Cell Stem Cell 2010, 7:150-161.
    • (2010) Cell Stem Cell , vol.7 , pp. 150-161
    • Mohyeldin, A.1    Garzón-Muvdi, T.2    Quiñones-Hinojosa, A.3
  • 145
    • 0242667922 scopus 로고    scopus 로고
    • Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation
    • Molofsky A.V., Pardal R., Iwashita T., Park I.K., Clarke M.F., Morrison S.J. Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation. Nature 2003, 425:962-967.
    • (2003) Nature , vol.425 , pp. 962-967
    • Molofsky, A.V.1    Pardal, R.2    Iwashita, T.3    Park, I.K.4    Clarke, M.F.5    Morrison, S.J.6
  • 146
    • 22344449361 scopus 로고    scopus 로고
    • Bmi-1 promotes neural stem cell self-renewal and neural development but not mouse growth and survival by repressing the p16Ink4a and p19Arf senescence pathways
    • Molofsky A.V., He S., Bydon M., Morrison S.J., Pardal R. Bmi-1 promotes neural stem cell self-renewal and neural development but not mouse growth and survival by repressing the p16Ink4a and p19Arf senescence pathways. Genes Dev. 2005, 19:1432-1437.
    • (2005) Genes Dev. , vol.19 , pp. 1432-1437
    • Molofsky, A.V.1    He, S.2    Bydon, M.3    Morrison, S.J.4    Pardal, R.5
  • 148
    • 0345189366 scopus 로고    scopus 로고
    • Inflammatory blockade restores adult hippocampal neurogenesis
    • Monje M.L., Toda H., Palmer T.D. Inflammatory blockade restores adult hippocampal neurogenesis. Science 2003, 302:1760-1765.
    • (2003) Science , vol.302 , pp. 1760-1765
    • Monje, M.L.1    Toda, H.2    Palmer, T.D.3
  • 149
    • 34547520932 scopus 로고    scopus 로고
    • Leukemogenesis of the EVI1/MEL1 gene family
    • Morishita K. Leukemogenesis of the EVI1/MEL1 gene family. Int. J. Hematol. 2007, 85:279-286.
    • (2007) Int. J. Hematol. , vol.85 , pp. 279-286
    • Morishita, K.1
  • 150
    • 33745600820 scopus 로고    scopus 로고
    • Asymmetric and symmetric stem-cell divisions in development and cancer
    • Morrison S.J., Kimble J. Asymmetric and symmetric stem-cell divisions in development and cancer. Nature 2006, 441:1068-1074.
    • (2006) Nature , vol.441 , pp. 1068-1074
    • Morrison, S.J.1    Kimble, J.2
  • 151
    • 39149144034 scopus 로고    scopus 로고
    • Stem cells and niches: mechanisms that promote stem cell maintenance throughout life
    • Morrison S.J., Spradling A.C. Stem cells and niches: mechanisms that promote stem cell maintenance throughout life. Cell 2008, 132:598-611.
    • (2008) Cell , vol.132 , pp. 598-611
    • Morrison, S.J.1    Spradling, A.C.2
  • 153
    • 0030248792 scopus 로고    scopus 로고
    • Telomerase activity in hematopoietic cells is associated with self-renewal potential
    • Morrison S.J., Prowse K.R., Ho P., Weissman I.L. Telomerase activity in hematopoietic cells is associated with self-renewal potential. Immunity 1996, 5:207-216.
    • (1996) Immunity , vol.5 , pp. 207-216
    • Morrison, S.J.1    Prowse, K.R.2    Ho, P.3    Weissman, I.L.4
  • 155
    • 78649811793 scopus 로고    scopus 로고
    • Lkb1 regulates cell cycle and energy metabolism in haematopoietic stem cells
    • Nakada D., Saunders T.L., Morrison S.J. Lkb1 regulates cell cycle and energy metabolism in haematopoietic stem cells. Nature 2010, 468:653-658.
    • (2010) Nature , vol.468 , pp. 653-658
    • Nakada, D.1    Saunders, T.L.2    Morrison, S.J.3
  • 157
    • 0142183452 scopus 로고    scopus 로고
    • A novel EVI1 gene family, MEL1, lacking a PR domain (MEL1S) is expressed mainly in t(1;3)(p36;q21)-positive AML and blocks G-CSF-induced myeloid differentiation
    • Nishikata I., Sasaki H., Iga M., Tateno Y., Imayoshi S., Asou N., Nakamura T., Morishita K. A novel EVI1 gene family, MEL1, lacking a PR domain (MEL1S) is expressed mainly in t(1;3)(p36;q21)-positive AML and blocks G-CSF-induced myeloid differentiation. Blood 2003, 102:3323-3332.
    • (2003) Blood , vol.102 , pp. 3323-3332
    • Nishikata, I.1    Sasaki, H.2    Iga, M.3    Tateno, Y.4    Imayoshi, S.5    Asou, N.6    Nakamura, T.7    Morishita, K.8
  • 158
    • 53749098061 scopus 로고    scopus 로고
    • Hmga2 promotes neural stem cell self-renewal in young but not old mice by reducing p16Ink4a and p19Arf Expression
    • Nishino J., Kim I., Chada K., Morrison S.J. Hmga2 promotes neural stem cell self-renewal in young but not old mice by reducing p16Ink4a and p19Arf Expression. Cell 2008, 135:227-239.
    • (2008) Cell , vol.135 , pp. 227-239
    • Nishino, J.1    Kim, I.2    Chada, K.3    Morrison, S.J.4
  • 159
    • 33749350639 scopus 로고    scopus 로고
    • Differential impact of Ink4a and Arf on hematopoietic stem cells and their bone marrow microenvironment in Bmi1-deficient mice
    • Oguro H., Iwama A., Morita Y., Kamijo T., van Lohuizen M., Nakauchi H. Differential impact of Ink4a and Arf on hematopoietic stem cells and their bone marrow microenvironment in Bmi1-deficient mice. J. Exp. Med. 2006, 203:2247-2253.
    • (2006) J. Exp. Med. , vol.203 , pp. 2247-2253
    • Oguro, H.1    Iwama, A.2    Morita, Y.3    Kamijo, T.4    van Lohuizen, M.5    Nakauchi, H.6
  • 163
    • 33746459740 scopus 로고    scopus 로고
    • Stem cell self-renewal and cancer cell proliferation are regulated by common networks that balance the activation of proto-oncogenes and tumor suppressors
    • Pardal R., Molofsky A.V., He S., Morrison S.J. Stem cell self-renewal and cancer cell proliferation are regulated by common networks that balance the activation of proto-oncogenes and tumor suppressors. Cold Spring Harb. Symp. Quant. Biol. 2005, 70:177-185.
    • (2005) Cold Spring Harb. Symp. Quant. Biol. , vol.70 , pp. 177-185
    • Pardal, R.1    Molofsky, A.V.2    He, S.3    Morrison, S.J.4
  • 164
    • 35348906206 scopus 로고    scopus 로고
    • Glia-like stem cells sustain physiologic neurogenesis in the adult mammalian carotid body
    • Pardal R., Ortega-Sáenz P., Durán R., López-Barneo J. Glia-like stem cells sustain physiologic neurogenesis in the adult mammalian carotid body. Cell 2007, 131:364-377.
    • (2007) Cell , vol.131 , pp. 364-377
    • Pardal, R.1    Ortega-Sáenz, P.2    Durán, R.3    López-Barneo, J.4
  • 165
    • 0041306120 scopus 로고    scopus 로고
    • Injury-induced neurogenesis in the adult mammalian brain
    • Parent J.M. Injury-induced neurogenesis in the adult mammalian brain. Neuroscientist 2003, 9:261-272.
    • (2003) Neuroscientist , vol.9 , pp. 261-272
    • Parent, J.M.1
  • 166
    • 0036895463 scopus 로고    scopus 로고
    • Rat forebrain neurogenesis and striatal neuron replacement after focal stroke
    • Parent J.M., Vexler Z.S., Gong C., Derugin N., Ferriero D.M. Rat forebrain neurogenesis and striatal neuron replacement after focal stroke. Ann. Neurol. 2002, 52:802-813.
    • (2002) Ann. Neurol. , vol.52 , pp. 802-813
    • Parent, J.M.1    Vexler, Z.S.2    Gong, C.3    Derugin, N.4    Ferriero, D.M.5
  • 169
    • 34248359065 scopus 로고    scopus 로고
    • Distribution of hematopoietic stem cells in the bone marrow according to regional hypoxia
    • Parmar K., Mauch P., Vergilio J.A., Sackstein R., Down J.D. Distribution of hematopoietic stem cells in the bone marrow according to regional hypoxia. Proc. Natl. Acad. Sci. USA 2007, 104:5431-5436.
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 5431-5436
    • Parmar, K.1    Mauch, P.2    Vergilio, J.A.3    Sackstein, R.4    Down, J.D.5
  • 170
    • 65549112127 scopus 로고    scopus 로고
    • Simultaneous prospective purification of adult subventricular zone neural stem cells and their progeny
    • Pastrana E., Cheng L.C., Doetsch F. Simultaneous prospective purification of adult subventricular zone neural stem cells and their progeny. Proc. Natl. Acad. Sci. USA 2009, 106:6387-6392.
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 6387-6392
    • Pastrana, E.1    Cheng, L.C.2    Doetsch, F.3
  • 173
    • 77951002352 scopus 로고    scopus 로고
    • The senescence-related mitochondrial/oxidative stress pathway is repressed in human induced pluripotent stem cells
    • Prigione A., Fauler B., Lurz R., Lehrach H., Adjaye J. The senescence-related mitochondrial/oxidative stress pathway is repressed in human induced pluripotent stem cells. Stem Cells 2010, 28:721-733.
    • (2010) Stem Cells , vol.28 , pp. 721-733
    • Prigione, A.1    Fauler, B.2    Lurz, R.3    Lehrach, H.4    Adjaye, J.5
  • 176
    • 3042852748 scopus 로고    scopus 로고
    • Neural stem cells in the subventricular zone are resilient to hypoxia/ischemia whereas progenitors are vulnerable
    • Romanko M.J., Rothstein R.P., Levison S.W. Neural stem cells in the subventricular zone are resilient to hypoxia/ischemia whereas progenitors are vulnerable. J. Cereb. Blood Flow Metab. 2004, 24:814-825.
    • (2004) J. Cereb. Blood Flow Metab. , vol.24 , pp. 814-825
    • Romanko, M.J.1    Rothstein, R.P.2    Levison, S.W.3
  • 177
    • 34250007142 scopus 로고    scopus 로고
    • Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age
    • Rossi D.J., Bryder D., Seita J., Nussenzweig A., Hoeijmakers J., Weissman I.L. Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age. Nature 2007, 447:725-729.
    • (2007) Nature , vol.447 , pp. 725-729
    • Rossi, D.J.1    Bryder, D.2    Seita, J.3    Nussenzweig, A.4    Hoeijmakers, J.5    Weissman, I.L.6
  • 178
    • 39149086121 scopus 로고    scopus 로고
    • Stems cells and the pathways to aging and cancer
    • Rossi D.J., Jamieson C.H., Weissman I.L. Stems cells and the pathways to aging and cancer. Cell 2008, 132:681-696.
    • (2008) Cell , vol.132 , pp. 681-696
    • Rossi, D.J.1    Jamieson, C.H.2    Weissman, I.L.3
  • 179
    • 0035997367 scopus 로고    scopus 로고
    • Metabolism and the control of circadian rhythms
    • Rutter J., Reick M., Mcknight S.L. Metabolism and the control of circadian rhythms. Annu. Rev. Biochem. 2002, 71:307-331.
    • (2002) Annu. Rev. Biochem. , vol.71 , pp. 307-331
    • Rutter, J.1    Reick, M.2    Mcknight, S.L.3
  • 181
    • 41549135942 scopus 로고    scopus 로고
    • FoxO transcription factors in the maintenance of cellular homeostasis during aging
    • Salih D.A., Brunet A. FoxO transcription factors in the maintenance of cellular homeostasis during aging. Curr. Opin. Cell Biol. 2008, 20:126-136.
    • (2008) Curr. Opin. Cell Biol. , vol.20 , pp. 126-136
    • Salih, D.A.1    Brunet, A.2
  • 182
    • 67149091317 scopus 로고    scopus 로고
    • Interferon regulatory factor-2 protects quiescent hematopoietic stem cells from type I interferon-dependent exhaustion
    • Sato T., Onai N., Yoshihara H., Arai F., Suda T., Ohteki T. Interferon regulatory factor-2 protects quiescent hematopoietic stem cells from type I interferon-dependent exhaustion. Nat. Med. 2009, 15:696-700.
    • (2009) Nat. Med. , vol.15 , pp. 696-700
    • Sato, T.1    Onai, N.2    Yoshihara, H.3    Arai, F.4    Suda, T.5    Ohteki, T.6
  • 183
    • 33745635043 scopus 로고    scopus 로고
    • The stem-cell niche as an entity of action
    • Scadden D.T. The stem-cell niche as an entity of action. Nature 2006, 441:1075-1079.
    • (2006) Nature , vol.441 , pp. 1075-1079
    • Scadden, D.T.1
  • 186
    • 70349237414 scopus 로고    scopus 로고
    • Involvement of oxygen-sensing pathways in physiologic and pathologic erythropoiesis
    • Semenza G.L. Involvement of oxygen-sensing pathways in physiologic and pathologic erythropoiesis. Blood 2009, 114:2015-2019.
    • (2009) Blood , vol.114 , pp. 2015-2019
    • Semenza, G.L.1
  • 187
    • 67749111502 scopus 로고    scopus 로고
    • The LKB1-AMPK pathway: metabolism and growth control in tumour suppression
    • Shackelford D.B., Shaw R.J. The LKB1-AMPK pathway: metabolism and growth control in tumour suppression. Nat. Rev. Cancer 2009, 9:563-575.
    • (2009) Nat. Rev. Cancer , vol.9 , pp. 563-575
    • Shackelford, D.B.1    Shaw, R.J.2
  • 188
  • 190
    • 50849142558 scopus 로고    scopus 로고
    • Adult SVZ stem cells lie in a vascular niche: a quantitative analysis of niche cell-cell interactions
    • Shen Q., Wang Y., Kokovay E., Lin G., Chuang S.M., Goderie S.K., Roysam B., Temple S. Adult SVZ stem cells lie in a vascular niche: a quantitative analysis of niche cell-cell interactions. Cell Stem Cell 2008, 3:289-300.
    • (2008) Cell Stem Cell , vol.3 , pp. 289-300
    • Shen, Q.1    Wang, Y.2    Kokovay, E.3    Lin, G.4    Chuang, S.M.5    Goderie, S.K.6    Roysam, B.7    Temple, S.8
  • 193
    • 0034730151 scopus 로고    scopus 로고
    • Redox state is a central modulator of the balance between self-renewal and differentiation in a dividing glial precursor cell
    • Smith J., Ladi E., Mayer-Proschel M., Noble M. Redox state is a central modulator of the balance between self-renewal and differentiation in a dividing glial precursor cell. Proc. Natl. Acad. Sci. USA 2000, 97:10032-10037.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 10032-10037
    • Smith, J.1    Ladi, E.2    Mayer-Proschel, M.3    Noble, M.4
  • 195
    • 79953044605 scopus 로고    scopus 로고
    • Fat cells reactivate quiescent neuroblasts via TOR and glial insulin relays in Drosophila
    • Sousa-Nunes R., Yee L.L., Gould A.P. Fat cells reactivate quiescent neuroblasts via TOR and glial insulin relays in Drosophila. Nature 2011, 471:508-512.
    • (2011) Nature , vol.471 , pp. 508-512
    • Sousa-Nunes, R.1    Yee, L.L.2    Gould, A.P.3
  • 196
    • 77958569435 scopus 로고    scopus 로고
    • Induced pluripotency: history, mechanisms, and applications
    • Stadtfeld M., Hochedlinger K. Induced pluripotency: history, mechanisms, and applications. Genes Dev. 2010, 24:2239-2263.
    • (2010) Genes Dev. , vol.24 , pp. 2239-2263
    • Stadtfeld, M.1    Hochedlinger, K.2
  • 197
    • 33747195353 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
    • Takahashi K., Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006, 126:663-676.
    • (2006) Cell , vol.126 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 198
    • 0029026103 scopus 로고
    • The cell cycle of the pseudostratified ventricular epithelium of the embryonic murine cerebral wall
    • Takahashi T., Nowakowski R.S., Caviness V.S. The cell cycle of the pseudostratified ventricular epithelium of the embryonic murine cerebral wall. J. Neurosci. 1995, 15:6046-6057.
    • (1995) J. Neurosci. , vol.15 , pp. 6046-6057
    • Takahashi, T.1    Nowakowski, R.S.2    Caviness, V.S.3
  • 199
    • 36248966518 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from adult human fibroblasts by defined factors
    • Takahashi K., Tanabe K., Ohnuki M., Narita M., Ichisaka T., Tomoda K., Yamanaka S. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007, 131:861-872.
    • (2007) Cell , vol.131 , pp. 861-872
    • Takahashi, K.1    Tanabe, K.2    Ohnuki, M.3    Narita, M.4    Ichisaka, T.5    Tomoda, K.6    Yamanaka, S.7
  • 200
    • 52149109334 scopus 로고    scopus 로고
    • The genetics of mammalian circadian order and disorder: implications for physiology and disease
    • Takahashi J.S., Hong H.K., Ko C.H., Mcdearmon E.L. The genetics of mammalian circadian order and disorder: implications for physiology and disease. Nat. Rev. Genet. 2008, 9:764-775.
    • (2008) Nat. Rev. Genet. , vol.9 , pp. 764-775
    • Takahashi, J.S.1    Hong, H.K.2    Ko, C.H.3    Mcdearmon, E.L.4
  • 203
    • 0035283153 scopus 로고    scopus 로고
    • Circulating insulin-like growth factor I mediates exercise-induced increases in the number of new neurons in the adult hippocampus
    • Trejo J.L., Carro E., Torres-Aleman I. Circulating insulin-like growth factor I mediates exercise-induced increases in the number of new neurons in the adult hippocampus. J. Neurosci. 2001, 21:1628-1634.
    • (2001) J. Neurosci. , vol.21 , pp. 1628-1634
    • Trejo, J.L.1    Carro, E.2    Torres-Aleman, I.3
  • 204
    • 33747591416 scopus 로고    scopus 로고
    • Metabolic cycles as an underlying basis of biological oscillations
    • Tu B.P., Mcknight S.L. Metabolic cycles as an underlying basis of biological oscillations. Nat. Rev. Mol. Cell Biol. 2006, 7:696-701.
    • (2006) Nat. Rev. Mol. Cell Biol. , vol.7 , pp. 696-701
    • Tu, B.P.1    Mcknight, S.L.2
  • 209
    • 25444533023 scopus 로고    scopus 로고
    • Exercise enhances learning and hippocampal neurogenesis in aged mice
    • van Praag H., Shubert T., Zhao C., Gage F.H. Exercise enhances learning and hippocampal neurogenesis in aged mice. J. Neurosci. 2005, 25:8680-8685.
    • (2005) J. Neurosci. , vol.25 , pp. 8680-8685
    • van Praag, H.1    Shubert, T.2    Zhao, C.3    Gage, F.H.4
  • 210
    • 66249108601 scopus 로고    scopus 로고
    • Understanding the Warburg effect: the metabolic requirements of cell proliferation
    • Vander Heiden M.G., Cantley L.C., Thompson C.B. Understanding the Warburg effect: the metabolic requirements of cell proliferation. Science 2009, 324:1029-1033.
    • (2009) Science , vol.324 , pp. 1029-1033
    • Vander Heiden, M.G.1    Cantley, L.C.2    Thompson, C.B.3
  • 212
  • 213
    • 12444279265 scopus 로고
    • On the origin of cancer cells
    • Warburg O. On the origin of cancer cells. Science 1956, 123:309-314.
    • (1956) Science , vol.123 , pp. 309-314
    • Warburg, O.1
  • 215
  • 219
    • 33846607211 scopus 로고    scopus 로고
    • Asymmetric inheritance of mother versus daughter centrosome in stem cell division
    • Yamashita Y.M., Mahowald A.P., Perlin J.R., Fuller M.T. Asymmetric inheritance of mother versus daughter centrosome in stem cell division. Science 2007, 315:518-521.
    • (2007) Science , vol.315 , pp. 518-521
    • Yamashita, Y.M.1    Mahowald, A.P.2    Perlin, J.R.3    Fuller, M.T.4
  • 220
    • 33646376411 scopus 로고    scopus 로고
    • Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells
    • Yilmaz O.H., Valdez R., Theisen B.K., Guo W., Ferguson D.O., Wu H., Morrison S.J. Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells. Nature 2006, 441:475-482.
    • (2006) Nature , vol.441 , pp. 475-482
    • Yilmaz, O.H.1    Valdez, R.2    Theisen, B.K.3    Guo, W.4    Ferguson, D.O.5    Wu, H.6    Morrison, S.J.7
  • 224
    • 39149099035 scopus 로고    scopus 로고
    • A role for adult TLX-positive neural stem cells in learning and behaviour
    • Zhang C.L., Zou Y., He W., Gage F.H., Evans R.M. A role for adult TLX-positive neural stem cells in learning and behaviour. Nature 2008, 451:1004-1007.
    • (2008) Nature , vol.451 , pp. 1004-1007
    • Zhang, C.L.1    Zou, Y.2    He, W.3    Gage, F.H.4    Evans, R.M.5
  • 225
    • 39149107803 scopus 로고    scopus 로고
    • Mechanisms and functional implications of adult neurogenesis
    • Zhao C., Deng W., Gage F.H. Mechanisms and functional implications of adult neurogenesis. Cell 2008, 132:645-660.
    • (2008) Cell , vol.132 , pp. 645-660
    • Zhao, C.1    Deng, W.2    Gage, F.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.