-
2
-
-
0037062454
-
Constitutive telomerase expression promotes mammary carcinomas in aging mice
-
Artandi, S. E., Alson, S., Tietze, M. K., Sharpless, N. E., Ye, S., Greenberg, R. A., Castrillon, D. H., Horner, J. W., Weiler, S. R., Carrasco, R. D. and DePinho, R. A. (2002). Constitutive telomerase expression promotes mammary carcinomas in aging mice. Proc. Natl. Acad. Sci. USA 99, 8191-8196.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 8191-8196
-
-
Artandi, S.E.1
Alson, S.2
Tietze, M.K.3
Sharpless, N.E.4
Ye, S.5
Greenberg, R.A.6
Castrillon, D.H.7
Horner, J.W.8
Weiler, S.R.9
Carrasco, R.D.10
DePinho, R.A.11
-
3
-
-
0035694469
-
Acetylation of p53 activates transcription through recruitment of coactivators/histone acetyltransferases
-
Barlev, N. A., Liu, L., Chehab, N. H., Mansfield, K., Harris, K. G., Halazonetis, T. D. and Berger, S. L. (2001). Acetylation of p53 activates transcription through recruitment of coactivators/histone acetyltransferases. Mol. Cell 8, 1243-1254.
-
(2001)
Mol. Cell
, vol.8
, pp. 1243-1254
-
-
Barlev, N.A.1
Liu, L.2
Chehab, N.H.3
Mansfield, K.4
Harris, K.G.5
Halazonetis, T.D.6
Berger, S.L.7
-
4
-
-
0034597794
-
Telomere states and cell fates
-
Blackburn, E. H. (2000). Telomere states and cell fates. Nature 408, 53-56.
-
(2000)
Nature
, vol.408
, pp. 53-56
-
-
Blackburn, E.H.1
-
5
-
-
0030931491
-
Telomere shortening and tumor formation by mouse cells lacking telomerase RNA
-
Blasco, M. A., Lee, H. W., Hande, M. P., Samper, E., Lansdorp, P. M., DePinho, R. A. and Greider, C. W. (1997). Telomere shortening and tumor formation by mouse cells lacking telomerase RNA. Cell 91, 25-34.
-
(1997)
Cell
, vol.91
, pp. 25-34
-
-
Blasco, M.A.1
Lee, H.W.2
Hande, M.P.3
Samper, E.4
Lansdorp, P.M.5
DePinho, R.A.6
Greider, C.W.7
-
6
-
-
0036674425
-
Telomerase beyond telomeres
-
Blasco, M. A. (2002). Telomerase beyond telomeres. Nat. Rev. Cancer 2, 627-633.
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 627-633
-
-
Blasco, M.A.1
-
7
-
-
0010045614
-
Extension of life-span by introduction of telomerase into normal human cells
-
Bodnar, A. G., Ouellette, M., Frolkis, M., Holt, S. E., Chiu, C. P., Morin, G. B., Harley, C. B., Shay, J. W., Lichtsteiner, S. and Wright, W. E. (1998). Extension of life-span by introduction of telomerase into normal human cells. Science 279, 349-352.
-
(1998)
Science
, vol.279
, pp. 349-352
-
-
Bodnar, A.G.1
Ouellette, M.2
Frolkis, M.3
Holt, S.E.4
Chiu, C.P.5
Morin, G.B.6
Harley, C.B.7
Shay, J.W.8
Lichtsteiner, S.9
Wright, W.E.10
-
8
-
-
0037377060
-
Ubiquitination, phosphorylation and acetylation: The molecular basis for p53 regulation
-
Brooks, C. L. and Gu, W. (2003). Ubiquitination, phosphorylation and acetylation: the molecular basis for p53 regulation. Curr Opin Cell Biol. 15, 164-171.
-
(2003)
Curr. Opin. Cell Biol.
, vol.15
, pp. 164-171
-
-
Brooks, C.L.1
Gu, W.2
-
9
-
-
0042160196
-
Telomerase activity in the subventricular zone of adult mice
-
Caporaso, G. L., Lim, D. A., Alvarez-Buylla, A. and Chao, M. V. (2003). Telomerase activity in the subventricular zone of adult mice. Mol. Cell Neurosci. 23, 693-702.
-
(2003)
Mol. Cell Neurosci.
, vol.23
, pp. 693-702
-
-
Caporaso, G.L.1
Lim, D.A.2
Alvarez-Buylla, A.3
Chao, M.V.4
-
10
-
-
0033553516
-
p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis
-
Chin, L., Artandi, S. E., Shen, Q., Tam, A., Lee, S. L., Gottlieb, G. J., Greider, C. W. and DePinho, R. A. (1999). p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis. Cell 97, 527-538.
-
(1999)
Cell
, vol.97
, pp. 527-538
-
-
Chin, L.1
Artandi, S.E.2
Shen, Q.3
Tam, A.4
Lee, S.L.5
Gottlieb, G.J.6
Greider, C.W.7
DePinho, R.A.8
-
11
-
-
0031047426
-
Replicative senescence and cell immortality: The role of telomeres and telomerase
-
Chiu, C. P. and Harley, C. B. (1997). Replicative senescence and cell immortality: the role of telomeres and telomerase. Proc. Soc. Exp. Biol. Med. 214, 99-106.
-
(1997)
Proc. Soc. Exp. Biol. Med.
, vol.214
, pp. 99-106
-
-
Chiu, C.P.1
Harley, C.B.2
-
12
-
-
0344441890
-
A DNA damage checkpoint response in telomere-initiated senescence
-
d'Adda di Fagagna, F., Reaper, P. M., Clay-Farrace, L., Fiegler, H., Carr, P., Von Zglinicki, T., Saretzki, G., Carter, N. P. and Jackson, S. P. (2003). A DNA damage checkpoint response in telomere-initiated senescence. Nature 426, 194-198.
-
(2003)
Nature
, vol.426
, pp. 194-198
-
-
d'Adda di Fagagna, F.1
Reaper, P.M.2
Clay-Farrace, L.3
Fiegler, H.4
Carr, P.5
Von Zglinicki, T.6
Saretzki, G.7
Carter, N.P.8
Jackson, S.P.9
-
13
-
-
0037148277
-
Protection of mammalian telomeres
-
de Lange, T. (2002). Protection of mammalian telomeres. Oncogene 21, 532-540.
-
(2002)
Oncogene
, vol.21
, pp. 532-540
-
-
de Lange, T.1
-
14
-
-
0030979469
-
Cellular composition and three-dimensional organization of the subventricular germinal zone in the adult mammalian brain
-
Doetsch, F., Garcia-Verdugo, J. M. and Alvarez-Buylla, A. (1997). Cellular composition and three-dimensional organization of the subventricular germinal zone in the adult mammalian brain. J. Neurosci. 17, 5046-5061.
-
(1997)
J. Neurosci.
, vol.17
, pp. 5046-5061
-
-
Doetsch, F.1
Garcia-Verdugo, J.M.2
Alvarez-Buylla, A.3
-
15
-
-
0033040497
-
Subventricular zone astrocytes are neural stem cells in the adult mammalian brain
-
Doetsch, F., Caille, I., Lim, D. A., Garcia-Verdugo, J. M. and Alvarez-Buylla, A. (1999). Subventricular zone astrocytes are neural stem cells in the adult mammalian brain. Cell 97, 703-716.
-
(1999)
Cell
, vol.97
, pp. 703-716
-
-
Doetsch, F.1
Caille, I.2
Lim, D.A.3
Garcia-Verdugo, J.M.4
Alvarez-Buylla, A.5
-
16
-
-
0037112834
-
Functional interaction between DNA-PKcs and telomerase in telomere length maintenance
-
Espejel, S., Franco, S., Segura, A., Gae, D., Bailey, S. M., Taccioli, G. E. and Blasco, M. A. (2002b). Functional interaction between DNA-PKcs and telomerase in telomere length maintenance. EMBO J. 21, 6275-6287.
-
(2002)
EMBO J.
, vol.21
, pp. 6275-6287
-
-
Espejel, S.1
Franco, S.2
Segura, A.3
Gae, D.4
Bailey, S.M.5
Taccioli, G.E.6
Blasco, M.A.7
-
17
-
-
0030460869
-
Lack of neurotrophin-3 results in death of spinal sensory neurons and premature differentiation of their precursors
-
Fariñas, I., Yoshida, C. K., Backus, C. and Reichardt, L. F. (1996). Lack of neurotrophin-3 results in death of spinal sensory neurons and premature differentiation of their precursors. Neuron 17, 1065-1078.
-
(1996)
Neuron
, vol.17
, pp. 1065-1078
-
-
Fariñas, I.1
Yoshida, C.K.2
Backus, C.3
Reichardt, L.F.4
-
18
-
-
0034122088
-
The catalytic subunit of telomerase is expressed in developing brain neurons and serves a cell survival-promoting function
-
Fu, W., Killen, M., Culmsee, C., Dhar, S., Pandita, T. K. and Mattson, M. P. (2000). The catalytic subunit of telomerase is expressed in developing brain neurons and serves a cell survival-promoting function. J. Mol. Neurosci. 14, 3-15.
-
(2000)
J. Mol. Neurosci.
, vol.14
, pp. 3-15
-
-
Fu, W.1
Killen, M.2
Culmsee, C.3
Dhar, S.4
Pandita, T.K.5
Mattson, M.P.6
-
19
-
-
0034712047
-
Mammalian neural stem cells
-
Gage, F. H. (2000). Mammalian neural stem cells. Science 287, 1433-1438.
-
(2000)
Science
, vol.287
, pp. 1433-1438
-
-
Gage, F.H.1
-
20
-
-
0037418920
-
Neural stem cells: An overview
-
Galli, R., Gritti, A., Bonfanti, L. and Vescovi, A. L. (2003). Neural stem cells: an overview. Circ Res. 92, 598-608.
-
(2003)
Circ Res.
, vol.92
, pp. 598-608
-
-
Galli, R.1
Gritti, A.2
Bonfanti, L.3
Vescovi, A.L.4
-
21
-
-
0032417640
-
A critical role for DNA end-joining proteins in both lymphogenesis and neurogenesis
-
Gao, Y., Sun, Y., Frank, K. M., Dikkes, P., Fujiwara, Y., Seidl, K. J., Sekiguchi, J. M., Rathbun, G. A., Swat, W., Wang, J. et al. (1998). A critical role for DNA end-joining proteins in both lymphogenesis and neurogenesis. Cell 95, 891-902.
-
(1998)
Cell
, vol.95
, pp. 891-902
-
-
Gao, Y.1
Sun, Y.2
Frank, K.M.3
Dikkes, P.4
Fujiwara, Y.5
Seidl, K.J.6
Sekiguchi, J.M.7
Rathbun, G.A.8
Swat, W.9
Wang, J.10
-
22
-
-
0032192140
-
The complexity of p53 modulation: Emerging patterns from divergent signals
-
Giaccia, A. J. and Kastanm M. B. (1998). The complexity of p53 modulation: emerging patterns from divergent signals. Genes Dev. 12, 2973-2983.
-
(1998)
Genes Dev.
, vol.12
, pp. 2973-2983
-
-
Giaccia, A.J.1
Kastanm, M.B.2
-
23
-
-
0035355340
-
Increased epidermal tumors and increased skin wound healing in transgenic mice overexpressing the catalytic subunit of telomerase, mTERT, in basal keratinocytes
-
González-Suárez, E., Samper, E., Ramírez, A., Flores, J. M., Martin-Caballero, J., Jorcano, J. L. and Blasco, M. A. (2001). Increased epidermal tumors and increased skin wound healing in transgenic mice overexpressing the catalytic subunit of telomerase, mTERT, in basal keratinocytes. EMBO J. 20, 619-630.
-
(2001)
EMBO J.
, vol.20
, pp. 619-630
-
-
González-Suárez, E.1
Samper, E.2
Ramírez, A.3
Flores, J.M.4
Martin-Caballero, J.5
Jorcano, J.L.6
Blasco, M.A.7
-
24
-
-
0036787840
-
Cooperation between p53 mutation and high telomerase transgenic expression in spontaneous cancer development
-
González-Suárez, E., Flores, J. M. and Blasco, M. A. (2002). Cooperation between p53 mutation and high telomerase transgenic expression in spontaneous cancer development. Mol. Cell. Biol. 22, 7291-7301.
-
(2002)
Mol. Cell Biol.
, vol.22
, pp. 7291-7301
-
-
González-Suárez, E.1
Flores, J.M.2
Blasco, M.A.3
-
25
-
-
0037148330
-
Many ways to telomere dysfunction: In vivo studies using mouse models
-
Goytisolo, F. A. and Blasco, M. A. (2002), Many ways to telomere dysfunction: in vivo studies using mouse models. Oncogene 21, 584-591.
-
(2002)
Oncogene
, vol.21
, pp. 584-591
-
-
Goytisolo, F.A.1
Blasco, M.A.2
-
26
-
-
0032473931
-
Expression of mouse telomerase reverse transcriptase during development, differentiation and proliferation
-
Greenberg, R. A., Allsopp, R. C., Chin, L., Morin, G. B. and DePinho, R. A. (1998). Expression of mouse telomerase reverse transcriptase during development, differentiation and proliferation. Oncogene 16, 1723-1730.
-
(1998)
Oncogene
, vol.16
, pp. 1723-1730
-
-
Greenberg, R.A.1
Allsopp, R.C.2
Chin, L.3
Morin, G.B.4
DePinho, R.A.5
-
27
-
-
0032567975
-
Telomeres and senescence: The history, the experiment, the future
-
Greider, C. W. (1998). Telomeres and senescence: the history, the experiment, the future. Curr. Biol. 8, 178-181.
-
(1998)
Curr. Biol.
, vol.8
, pp. 178-181
-
-
Greider, C.W.1
-
28
-
-
0029971286
-
Multipotential stem cells from the adult mouse brain proliferate and self-renew in response to basic fibroblast growth factor
-
Gritti, A., Parati, E. A., Cova, L., Frolichsthal, P., Galli, R., Wanke, E., Faravelli, L., Morassutti, D. J., Roisen, F., Nickel, D. D. and Vescovi, A. L. (1996). Multipotential stem cells from the adult mouse brain proliferate and self-renew in response to basic fibroblast growth factor. J. Neurosci. 16, 1091-1100.
-
(1996)
J. Neurosci.
, vol.16
, pp. 1091-1100
-
-
Gritti, A.1
Parati, E.A.2
Cova, L.3
Frolichsthal, P.4
Galli, R.5
Wanke, E.6
Faravelli, L.7
Morassutti, D.J.8
Roisen, F.9
Nickel, D.D.10
Vescovi, A.L.11
-
29
-
-
0344848564
-
Epidermal and fibroblast growth factors behave as mitogenic regulators for a single multipotent stem cell-like population from the subventricular region of the adult mouse forebrain
-
Gritti, A., Frolichsthal-Schoeller, P., Galli, R., Parati, E. A., Cova, L., Pagano, S. F., Bjornson, C. R. and Vescovi, A. L. (1999). Epidermal and fibroblast growth factors behave as mitogenic regulators for a single multipotent stem cell-like population from the subventricular region of the adult mouse forebrain. J. Neurosci. 19, 3287-3297.
-
(1999)
J. Neurosci.
, vol.19
, pp. 3287-3297
-
-
Gritti, A.1
Frolichsthal-Schoeller, P.2
Galli, R.3
Parati, E.A.4
Cova, L.5
Pagano, S.F.6
Bjornson, C.R.7
Vescovi, A.L.8
-
30
-
-
0035824396
-
Negative regulation of neural stem/progenitor cell proliferation by the Pten tumor suppressor gene in vivo
-
Groszer, M., Erickson, R., Scripture-Adams, D. D., Lesche, R., Trumpp, A., Zack, J. A., Kornblum, H. I., Liu, X. and Wu, H. (2001). Negative regulation of neural stem/progenitor cell proliferation by the Pten tumor suppressor gene in vivo. Science 294, 2186-2189.
-
(2001)
Science
, vol.294
, pp. 2186-2189
-
-
Groszer, M.1
Erickson, R.2
Scripture-Adams, D.D.3
Lesche, R.4
Trumpp, A.5
Zack, J.A.6
Kornblum, H.I.7
Liu, X.8
Wu, H.9
-
31
-
-
0034646304
-
Defective embryonic neurogenesis in Ku-deficient but not DNA-dependent protein kinase catalytic subunit-deficient mice
-
Gu, Y., Sekiguchi, J., Gao, Y., Dikkes, P., Frank, K., Ferguson, D., Hasty, P., Chun, J. and Alt, F. W. (2000). Defective embryonic neurogenesis in Ku-deficient but not DNA-dependent protein kinase catalytic subunit-deficient mice. Proc. Natl. Acad. Sci. USA 97, 2668-2673.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 2668-2673
-
-
Gu, Y.1
Sekiguchi, J.2
Gao, Y.3
Dikkes, P.4
Frank, K.5
Ferguson, D.6
Hasty, P.7
Chun, J.8
Alt, F.W.9
-
32
-
-
0034660459
-
Fibroblast growth factor 2 up regulates telomerase activity in neural precursor cells
-
Haik, S., Gauthier, L. R., Granotier, C., Peyrin, J. M., Lages, C. S., Dormont, D. and Boussin, F. D. (2000). Fibroblast growth factor 2 up regulates telomerase activity in neural precursor cells. Oncogene 19, 2957-2966.
-
(2000)
Oncogene
, vol.19
, pp. 2957-2966
-
-
Haik, S.1
Gauthier, L.R.2
Granotier, C.3
Peyrin, J.M.4
Lages, C.S.5
Dormont, D.6
Boussin, F.D.7
-
33
-
-
0033593814
-
Telomere length dynamics and chromosomal instability in cells derived from telomerase null mice
-
Hande, M. P., Samper, E., Lansdorp, P. and Blasco, M. A. (1999). Telomere length dynamics and chromosomal instability in cells derived from telomerase null mice. J. Cell Biol. 144, 589-601.
-
(1999)
J. Cell Biol.
, vol.144
, pp. 589-601
-
-
Hande, M.P.1
Samper, E.2
Lansdorp, P.3
Blasco, M.A.4
-
34
-
-
0025279931
-
Telomeres shorten during ageing of human fibroblasts
-
Harley, C. B., Futcher, A. B. and Greider, C. W. (1990). Telomeres shorten during ageing of human fibroblasts. Nature 345, 458-460.
-
(1990)
Nature
, vol.345
, pp. 458-460
-
-
Harley, C.B.1
Futcher, A.B.2
Greider, C.W.3
-
35
-
-
0035812845
-
The shortest telomere, not average telomere length, is critical for cell viability and chromosome stability
-
Hemann, M. T., Strong, M. A., Hao, L. Y. and Greider, C. W. (2001). The shortest telomere, not average telomere length, is critical for cell viability and chromosome stability. Cell 107, 67-77.
-
(2001)
Cell
, vol.107
, pp. 67-77
-
-
Hemann, M.T.1
Strong, M.A.2
Hao, L.Y.3
Greider, C.W.4
-
36
-
-
0033153424
-
Disease states associated to telomerase deficiency appear earlier in mice with short telomeres
-
Herrera, E., Samper, E., Martin-Caballero, J., Flores, J. M., Lee, H. W. and Blasco M. A. (1999a). Disease states associated to telomerase deficiency appear earlier in mice with short telomeres. EMBO J. 18, 2950-2960.
-
(1999)
EMBO J.
, vol.18
, pp. 2950-2960
-
-
Herrera, E.1
Samper, E.2
Martin-Caballero, J.3
Flores, J.M.4
Lee, H.W.5
Blasco, M.A.6
-
37
-
-
0033104511
-
-/- embryos is associated with failure to close the neural tube
-
-/- embryos is associated with failure to close the neural tube EMBO J. 18, 1172-1181.
-
(1999)
EMBO J.
, vol.18
, pp. 1172-1181
-
-
Herrera, E.1
Samper, E.2
Blasco, M.A.3
-
38
-
-
0343750697
-
Impaired germinal center reaction in mice with short telomeres
-
Herrera, E., Martinez-A, C. and Blasco, M. A. (2000). Impaired germinal center reaction in mice with short telomeres. EMBO J. 19, 472-481.
-
(2000)
EMBO J.
, vol.19
, pp. 472-481
-
-
Herrera, E.1
Martinez-A, C.2
Blasco, M.A.3
-
39
-
-
0030448423
-
Single factors direct the differentiation of stem cells from the fetal and adult central nervous system
-
Johe, K. K., Hazel, T. G., Muller, T., Dugich-Dlorjevic, M. M. and McKay, R. D. G. (1996). Single factors direct the differentiation of stem cells from the fetal and adult central nervous system. Genes Dev. 10, 3129-3140.
-
(1996)
Genes Dev.
, vol.10
, pp. 3129-3140
-
-
Johe, K.K.1
Hazel, T.G.2
Muller, T.3
Dugich-Dlorjevic, M.M.4
McKay, R.D.G.5
-
40
-
-
0034176261
-
Recombination in telomere-length maintenance
-
Kass-Eisler, A. and Greider, C. W. (2000). Recombination in telomere-length maintenance. Trends Biochem. Sci. 25, 200-204.
-
(2000)
Trends Biochem. Sci.
, vol.25
, pp. 200-204
-
-
Kass-Eisler, A.1
Greider, C.W.2
-
41
-
-
0028564951
-
Specific association of human telomerase activity with immortal cells and cancer
-
Kim, N. W., Piatyszek, M. A., Prowse, K. R., Harley, C. B., West, M. D., Ho, P. L., Coviello, G. M., Wright, W. E., Weinrich, S. L. and Shay, J. W. (1994). Specific association of human telomerase activity with immortal cells and cancer. Science 266, 2011-2014.
-
(1994)
Science
, vol.266
, pp. 2011-2014
-
-
Kim, N.W.1
Piatyszek, M.A.2
Prowse, K.R.3
Harley, C.B.4
West, M.D.5
Ho, P.L.6
Coviello, G.M.7
Wright, W.E.8
Weinrich, S.L.9
Shay, J.W.10
-
42
-
-
0035339824
-
Differential regulation of telomerase activity and TERT expression during brain development in mice
-
Klapper, W., Shin, T. and Mattson, M. P. (2001). Differential regulation of telomerase activity and TERT expression during brain development in mice. J. Neurosci. Res. 64, 252-260.
-
(2001)
J. Neurosci. Res.
, vol.64
, pp. 252-260
-
-
Klapper, W.1
Shin, T.2
Mattson, M.P.3
-
43
-
-
0037218819
-
Sonic hedgehog regulates adult neural progenitor proliferation in vitro and in vivo
-
Lai, K., Kaspar, B. K., Gage, F. H. and Schaffer, D. V. (2003). Sonic hedgehog regulates adult neural progenitor proliferation in vitro and in vivo. Nat. Neurosci. 6, 21-27.
-
(2003)
Nat. Neurosci.
, vol.6
, pp. 21-27
-
-
Lai, K.1
Kaspar, B.K.2
Gage, F.H.3
Schaffer, D.V.4
-
44
-
-
0037093346
-
Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence
-
Langley, E., Pearson, M., Faretta, M., Bauer, U. M., Frye, R. A., Minucci, S., Pelicci, P. G. and Kouzarides, T. (2002). Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence. EMBO J. 21, 2383-2396.
-
(2002)
EMBO J.
, vol.21
, pp. 2383-2396
-
-
Langley, E.1
Pearson, M.2
Faretta, M.3
Bauer, U.M.4
Frye, R.A.5
Minucci, S.6
Pelicci, P.G.7
Kouzarides, T.8
-
45
-
-
0032499210
-
Essential role of mouse telomerase in highly proliferative organs
-
Lee, H. W., Blasco, M. A., Gottlieb, G. J., Horner, J. W., II, Greider, C. W. and DePinho, R. A. (1998). Essential role of mouse telomerase in highly proliferative organs. Nature 392, 569-574.
-
(1998)
Nature
, vol.392
, pp. 569-574
-
-
Lee, H.W.1
Blasco, M.A.2
Gottlieb, G.J.3
Horner II, J.W.4
Greider, C.W.5
DePinho, R.A.6
-
46
-
-
0037413726
-
Ablation of telomerase and telomere loss leads to cardiac dilatation and heart failure associated with p53 upregulation
-
Leri, A., Franco, S., Zacheo, A., Barlucchi, L., Chimenti, S., Limana, F., Nadal-Ginard, B., Kajstura, J., Anversa, P. and Blasco, M. A. (2003). Ablation of telomerase and telomere loss leads to cardiac dilatation and heart failure associated with p53 upregulation. EMBO J. 22, 131-139.
-
(2003)
EMBO J.
, vol.22
, pp. 131-139
-
-
Leri, A.1
Franco, S.2
Zacheo, A.3
Barlucchi, L.4
Chimenti, S.5
Limana, F.6
Nadal-Ginard, B.7
Kajstura, J.8
Anversa, P.9
Blasco, M.A.10
-
47
-
-
0028361594
-
Long-distance neuronal migration in the adult mammalian brain
-
Lois, C. and Alvarez-Buylla, A. (1994). Long-distance neuronal migration in the adult mammalian brain. Science 264, 1145-1148.
-
(1994)
Science
, vol.264
, pp. 1145-1148
-
-
Lois, C.1
Alvarez-Buylla, A.2
-
48
-
-
0035913911
-
Negative control of p53 by Sir2alpha promotes cell survival under stress
-
Luo, J., Nikolaev, A. Y., Imai, S., Chen, D., Su, F., Shiloh, A., Guarente, L. and Gu, W. (2001). Negative control of p53 by Sir2alpha promotes cell survival under stress. Cell 107, 137-148.
-
(2001)
Cell
, vol.107
, pp. 137-148
-
-
Luo, J.1
Nikolaev, A.Y.2
Imai, S.3
Chen, D.4
Su, F.5
Shiloh, A.6
Guarente, L.7
Gu, W.8
-
49
-
-
0027291286
-
Restricted proliferation and migration of postnatally generated neurons derived from the forebrain subventricular zone
-
Luskin, M. B. (1993). Restricted proliferation and migration of postnatally generated neurons derived from the forebrain subventricular zone. Neuron 11, 173-189.
-
(1993)
Neuron
, vol.11
, pp. 173-189
-
-
Luskin, M.B.1
-
50
-
-
0032168370
-
Expression of mouse telomerase catalytic subunit in embryos and adult tissues
-
Martín-Rivera, L., Herrera, E., Albar, J. P. and Blasco, M. A. (1998). Expression of mouse telomerase catalytic subunit in embryos and adult tissues. Proc. Natl. Acad. Sci. USA 95, 10471-10476.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 10471-10476
-
-
Martín-Rivera, L.1
Herrera, E.2
Albar, J.P.3
Blasco, M.A.4
-
51
-
-
0035117940
-
Telomere length abnormalities in mammalian radiosensitive cells
-
McIlrath, J., Bouffler, S. D., Samper, E., Cuthbert, A., Wojcik, A., Szumiel, I., Bryant, P. E., Riches, A. C., Thompson, A., Blasco, M. A. et al. (2001). Telomere length abnormalities in mammalian radiosensitive cells. Cancer Res. 61, 912-915.
-
(2001)
Cancer Res.
, vol.61
, pp. 912-915
-
-
McIlrath, J.1
Bouffler, S.D.2
Samper, E.3
Cuthbert, A.4
Wojcik, A.5
Szumiel, I.6
Bryant, P.E.7
Riches, A.C.8
Thompson, A.9
Blasco, M.A.10
-
52
-
-
0030248792
-
Telomerase activity in hematopoietic cells is associated with self-renewal potential
-
Morrison, S. J., Prowse, K. R., Ho, P. and Weissman, I. L. (1996). Telomerase activity in hematopoietic cells is associated with self-renewal potential. Immunity 5, 201-216.
-
(1996)
Immunity
, vol.5
, pp. 201-216
-
-
Morrison, S.J.1
Prowse, K.R.2
Ho, P.3
Weissman, I.L.4
-
53
-
-
0028003778
-
Neural stem cells in the adult mammalian forebrain: A relatively quiescent subpopulation of subependymal cells
-
Morshead, C. M., Reynolds, B. A., Craig, C. G., McBurney, M. W., Staines, W. A., Morassutti, D., Weiss, S. and van der Kooy, D. (1994). Neural stem cells in the adult mammalian forebrain: a relatively quiescent subpopulation of subependymal cells. Neuron 13, 1071-1082.
-
(1994)
Neuron
, vol.13
, pp. 1071-1082
-
-
Morshead, C.M.1
Reynolds, B.A.2
Craig, C.G.3
McBurney, M.W.4
Staines, W.A.5
Morassutti, D.6
Weiss, S.7
van der Kooy, D.8
-
54
-
-
0034077143
-
Telomere maintenance in telomerase-deficient mouse embryonic stem cells: Characterization of an amplified telomeric DNA
-
Niida, H., Shinkai, Y., Hande, M. P., Matsumoto, T., Takehara, S., Tachibana, M., Oshimura, M., Lansdorp, P. M. and Furuichi, Y. (2000).Telomere maintenance in telomerase-deficient mouse embryonic stem cells: characterization of an amplified telomeric DNA. Mol. Cel. Biol. 20, 4115-4127.
-
(2000)
Mol. Cel. Biol.
, vol.20
, pp. 4115-4127
-
-
Niida, H.1
Shinkai, Y.2
Hande, M.P.3
Matsumoto, T.4
Takehara, S.5
Tachibana, M.6
Oshimura, M.7
Lansdorp, P.M.8
Furuichi, Y.9
-
55
-
-
0035839458
-
Roles of the basic helix-loop-helix genes Hes1 and Hes5 in expansion of neural stem cells of the developing brain
-
Ohtsuka, T., Sakamoto, M., Guillemot, F. and Kageyama, R. (2001). Roles of the basic helix-loop-helix genes Hes1 and Hes5 in expansion of neural stem cells of the developing brain. J. Biol. Chem. 276, 30467-30474.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 30467-30474
-
-
Ohtsuka, T.1
Sakamoto, M.2
Guillemot, F.3
Kageyama, R.4
-
56
-
-
0033929434
-
Human neural precursor cells express low levels of telomerase in vitro and show diminishing cell proliferation with extensive axonal outgrowth following transplantation
-
Ostenfeld, T., Cladwell, M. A., Prowse, K. R., Linskens, M. H., Jauniaux, E. and Svendsen, C. N. (2000). Human neural precursor cells express low levels of telomerase in vitro and show diminishing cell proliferation with extensive axonal outgrowth following transplantation. Exp. Neurol. 164, 215-226.
-
(2000)
Exp. Neurol.
, vol.164
, pp. 215-226
-
-
Ostenfeld, T.1
Cladwell, M.A.2
Prowse, K.R.3
Linskens, M.H.4
Jauniaux, E.5
Svendsen, C.N.6
-
57
-
-
0029040101
-
Developmental and tissue-specific regulation of mouse telomerase and telomere length
-
Prowse, K. R. and Greider, C. W. (1995). Developmental and tissue-specific regulation of mouse telomerase and telomere length. Proc. Natl. Acad. Sci. USA 92, 4818-4822.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 4818-4822
-
-
Prowse, K.R.1
Greider, C.W.2
-
58
-
-
0026535505
-
Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system
-
Reynolds, B. A. and Weiss, S. (1992). Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system. Science 255, 1707-1710.
-
(1992)
Science
, vol.255
, pp. 1707-1710
-
-
Reynolds, B.A.1
Weiss, S.2
-
59
-
-
0033525558
-
Longevity, stress response, and cancer in aging telomerase-deficient mice
-
Rudolph, K. L., Chang, S., Lee, H. W., Blasco, M. A., Gottlieb, G. J., Greider, C. and DePinho, R. A. (1999). Longevity, stress response, and cancer in aging telomerase-deficient mice. Cell 96, 701-712.
-
(1999)
Cell
, vol.96
, pp. 701-712
-
-
Rudolph, K.L.1
Chang, S.2
Lee, H.W.3
Blasco, M.A.4
Gottlieb, G.J.5
Greider, C.6
DePinho, R.A.7
-
60
-
-
0034769105
-
Restoration of telomerase activity rescues chromosomal instability and premature aging in Terc-/- mice with short telomeres
-
Samper, E., Flores, J. M. and Blasco, M. A. (2001). Restoration of telomerase activity rescues chromosomal instability and premature aging in Terc-/- mice with short telomeres. EMBO Reports 2, 800-807.
-
(2001)
EMBO Reports
, vol.2
, pp. 800-807
-
-
Samper, E.1
Flores, J.M.2
Blasco, M.A.3
-
61
-
-
0037089438
-
Long-term repopulating ability of telomerase-deficient murine hematopoietic stem cells
-
Samper, E., Fernández, P., Martín-Rivera, L., Bernad, A., Blasco, M. A. and Aracil, M. (2002). Long-term repopulating ability of telomerase-deficient murine hematopoietic stem cells. Blood 99, 2767-2775.
-
(2002)
Blood
, vol.99
, pp. 2767-2775
-
-
Samper, E.1
Fernández, P.2
Martín-Rivera, L.3
Bernad, A.4
Blasco, M.A.5
Aracil, M.6
-
62
-
-
0034682721
-
Cellular senescence: Mitotic clock or culture shock?
-
Sherr, C. J. and DePinho, R. A. (2000). Cellular senescence: mitotic clock or culture shock? Cell 102, 407-410.
-
(2000)
Cell
, vol.102
, pp. 407-410
-
-
Sherr, C.J.1
DePinho, R.A.2
-
63
-
-
0035478280
-
The ciliary neurotrophic factor/leukemia inhibitory factor/gp130 receptor complex operates in the maintenance of mammalian forebrain neural stem cells
-
Shimazaki, T., Shingo, T. and Weiss, S. (2001). The ciliary neurotrophic factor/leukemia inhibitory factor/gp130 receptor complex operates in the maintenance of mammalian forebrain neural stem cells. J. Neurosci. 21, 7642-7653.
-
(2001)
J. Neurosci.
, vol.21
, pp. 7642-7653
-
-
Shimazaki, T.1
Shingo, T.2
Weiss, S.3
-
64
-
-
0038056347
-
Telomerase modulates expression of growth-controlling genes and enhances cell proliferation
-
Smith, L. L., Coller, H. A. and Roberts, J. M. (2003).Telomerase modulates expression of growth-controlling genes and enhances cell proliferation. Nat. Cell Biol. 5, 474-479.
-
(2003)
Nat. Cell Biol.
, vol.5
, pp. 474-479
-
-
Smith, L.L.1
Coller, H.A.2
Roberts, J.M.3
-
65
-
-
0036792871
-
DNA ligase IV-dependent NHEJ of deprotected mammalian telomeres in G1 and G2
-
Smogorzewska, A., Karlseder, J., Holtgreve-Grez, H., Jauch, A. and de Lange, T. (2002). DNA ligase IV-dependent NHEJ of deprotected mammalian telomeres in G1 and G2. Curr. Biol. 12, 1635-1644.
-
(2002)
Curr. Biol.
, vol.12
, pp. 1635-1644
-
-
Smogorzewska, A.1
Karlseder, J.2
Holtgreve-Grez, H.3
Jauch, A.4
de Lange, T.5
-
66
-
-
0037102234
-
Different telomere damage signaling pathways in human and mouse cells
-
Smogorzewska, A. and de Lange, T. (2002). Different telomere damage signaling pathways in human and mouse cells. EMBO J. 21, 4338-4348.
-
(2002)
EMBO J.
, vol.21
, pp. 4338-4348
-
-
Smogorzewska, A.1
de Lange, T.2
-
67
-
-
0042420304
-
DNA damage foci at dysfunctional telomeres
-
Takai, H., Smogorzewska, A. and de Lange, T. (2003). DNA damage foci at dysfunctional telomeres. Curr. Biol. 13, 1549-1556.
-
(2003)
Curr. Biol.
, vol.13
, pp. 1549-1556
-
-
Takai, H.1
Smogorzewska, A.2
de Lange, T.3
-
68
-
-
0033635021
-
FGF-2-responsive neural stem cell proliferation requires CCg, a novel autocrine/paracrine cofactor
-
Taupin, P., Ray, J., Fischer, W. H., Suhr, S. T., Hakansson, K., Grubb, A. and Gage, F. H. (2000). FGF-2-responsive neural stem cell proliferation requires CCg, a novel autocrine/paracrine cofactor. Neuron 28, 385-397.
-
(2000)
Neuron
, vol.28
, pp. 385-397
-
-
Taupin, P.1
Ray, J.2
Fischer, W.H.3
Suhr, S.T.4
Hakansson, K.5
Grubb, A.6
Gage, F.H.7
-
69
-
-
0035499887
-
The development of neural stem cells
-
Temple, S. (2001). The development of neural stem cells. Nature 414, 112-127.
-
(2001)
Nature
, vol.414
, pp. 112-127
-
-
Temple, S.1
-
70
-
-
0032491416
-
Embryonic stem cell lines derived from human blastocysts
-
Thomson, J. A., Itskovitz-Eldor, J., Shapiro, S. S., Waknitz, M. A., Swiergiel, J. J., Marshall, V. S. and Jones, J. M. (1998). Embryonic stem cell lines derived from human blastocysts. Science 282, 1145-1147.
-
(1998)
Science
, vol.282
, pp. 1145-1147
-
-
Thomson, J.A.1
Itskovitz-Eldor, J.2
Shapiro, S.S.3
Waknitz, M.A.4
Swiergiel, J.J.5
Marshall, V.S.6
Jones, J.M.7
-
71
-
-
0030826603
-
Transforming growth factor-alpha null and senescent mice show decreased neural progenitor cell proliferation in the forebrain subependyma
-
Tropepe, V., Craig, C. G., Morshead, C. M. and van der Kooy, D. (1997).Transforming growth factor-alpha null and senescent mice show decreased neural progenitor cell proliferation in the forebrain subependyma. J. Neurosci. 17, 7850-7859.
-
(1997)
J. Neurosci.
, vol.17
, pp. 7850-7859
-
-
Tropepe, V.1
Craig, C.G.2
Morshead, C.M.3
van der Kooy, D.4
-
72
-
-
0028077099
-
Evidence for a mitotic clock in human hematopoietic stem cells: Loss of telomeric DNA with age
-
Vaziri, H., Dragowska, W., Allsopp, R. C., Thomas, T. E., Harley, C. B. and Lansdorp, P. M. (1994). Evidence for a mitotic clock in human hematopoietic stem cells: Loss of telomeric DNA with age. Proc. Natl. Acad. Sci. USA 91, 9857-9860.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 9857-9860
-
-
Vaziri, H.1
Dragowska, W.2
Allsopp, R.C.3
Thomas, T.E.4
Harley, C.B.5
Lansdorp, P.M.6
-
73
-
-
0035913903
-
hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase
-
Vaziri, H., Dessain, S. K., Ng Eaton, E., Imai, S. I., Frye, R. A., Pandita, T. K., Guarente, L. and Weinberg, R. A. (2001). hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase. Cell 107, 149-159.
-
(2001)
Cell
, vol.107
, pp. 149-159
-
-
Vaziri, H.1
Dessain, S.K.2
Ng Eaton, E.3
Imai, S.I.4
Frye, R.A.5
Pandita, T.K.6
Guarente, L.7
Weinberg, R.A.8
-
74
-
-
0034676455
-
Surfing the p53 network
-
Vogelstein, B., Lane, D. and Levine, A. J. (2000). Surfing the p53 network. Nature 408, 307-310.
-
(2000)
Nature
, vol.408
, pp. 307-310
-
-
Vogelstein, B.1
Lane, D.2
Levine, A.J.3
-
75
-
-
0037421896
-
Telomere dysfunction and Atm deficiency compromises organ homeostasis and accelerates ageing
-
Wong, K. K., Maser, R. S., Bachoo, R. M., Menon, J., Carrasco, D. R., Gu, Y., Alt, F. W. and DePinho, R. A. (2003). Telomere dysfunction and Atm deficiency compromises organ homeostasis and accelerates ageing. Nature 421, 643-648.
-
(2003)
Nature
, vol.421
, pp. 643-648
-
-
Wong, K.K.1
Maser, R.S.2
Bachoo, R.M.3
Menon, J.4
Carrasco, D.R.5
Gu, Y.6
Alt, F.W.7
DePinho, R.A.8
-
76
-
-
0036683054
-
Ets1 is required for p53 transcriptional activity in UV-induced apoptosis in embryonic stem cells
-
Xu, D., Wilson, T. J., Chan, D., De Luca, E., Zhou, J., Hertzog, P. J. and Kola, I. (2002). Ets1 is required for p53 transcriptional activity in UV-induced apoptosis in embryonic stem cells. EMBO J. 21, 4081-4093.
-
(2002)
EMBO J.
, vol.21
, pp. 4081-4093
-
-
Xu, D.1
Wilson, T.J.2
Chan, D.3
De Luca, E.4
Zhou, J.5
Hertzog, P.J.6
Kola, I.7
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