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Volumn 68, Issue 3, 2008, Pages 759-766

Loss of Lkb1 provokes highly invasive endometrial adenocarcinomas

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN KINASE LKB1;

EID: 38849193504     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-07-5014     Document Type: Article
Times cited : (93)

References (34)
  • 1
    • 0032495530 scopus 로고    scopus 로고
    • A serine/ threonine kinase gene defective in Peutz-Jeghers syndrome
    • Hemminki A, Markie D, Tomlinson I, et al. A serine/ threonine kinase gene defective in Peutz-Jeghers syndrome. Nature 1998;391:184-7.
    • (1998) Nature , vol.391 , pp. 184-187
    • Hemminki, A.1    Markie, D.2    Tomlinson, I.3
  • 3
    • 33744782567 scopus 로고    scopus 로고
    • Frequency and spectrum of cancers in the Peutz-Jeghers syndrome
    • Hearle N, Schumacher V, Menko FH, et al. Frequency and spectrum of cancers in the Peutz-Jeghers syndrome. Clin Cancer Res 2006;12:3209-15.
    • (2006) Clin Cancer Res , vol.12 , pp. 3209-3215
    • Hearle, N.1    Schumacher, V.2    Menko, F.H.3
  • 4
    • 0042525904 scopus 로고    scopus 로고
    • LKB1 protein expression in the evolution of glandular neoplasia of the lung
    • Ghaffar H, Sahin F, Sanchez-Cepedes M, et al. LKB1 protein expression in the evolution of glandular neoplasia of the lung. Clin Cancer Res 2003;9:2998-3003.
    • (2003) Clin Cancer Res , vol.9 , pp. 2998-3003
    • Ghaffar, H.1    Sahin, F.2    Sanchez-Cepedes, M.3
  • 5
    • 0034610730 scopus 로고    scopus 로고
    • Epigenetic inactivation of LKB1 in primary tumors associated with the Peutz-Jeghers syndrome
    • Esteller M, Avizienyte E, Corn PG, et al. Epigenetic inactivation of LKB1 in primary tumors associated with the Peutz-Jeghers syndrome. Oncogene 2000;19:164-8.
    • (2000) Oncogene , vol.19 , pp. 164-168
    • Esteller, M.1    Avizienyte, E.2    Corn, P.G.3
  • 6
    • 0035184065 scopus 로고    scopus 로고
    • STK11/LKB1 Peutz-Jeghers gene inactivation in intraductal papillary-mucinous neoplasms of the pancreas
    • Sato N, Rosty C, Jansen M, et al. STK11/LKB1 Peutz-Jeghers gene inactivation in intraductal papillary-mucinous neoplasms of the pancreas. Am J Pathol 2001;159:2017-22.
    • (2001) Am J Pathol , vol.159 , pp. 2017-2022
    • Sato, N.1    Rosty, C.2    Jansen, M.3
  • 7
    • 0036645286 scopus 로고    scopus 로고
    • Inactivation of LKB1/STK11 is a common event in adenocarcinomas of the lung
    • Sanchez-Cespedes M, Parrella P, Esteller M, et al. Inactivation of LKB1/STK11 is a common event in adenocarcinomas of the lung. Cancer Res 2002;62:3659-62.
    • (2002) Cancer Res , vol.62 , pp. 3659-3662
    • Sanchez-Cespedes, M.1    Parrella, P.2    Esteller, M.3
  • 8
    • 0036042804 scopus 로고    scopus 로고
    • Endocervical adenocarcinoma and its variants: Their morphology and differential diagnosis
    • Young RH, Clement PB. Endocervical adenocarcinoma and its variants: their morphology and differential diagnosis. Histopathology 2002;41:185-207.
    • (2002) Histopathology , vol.41 , pp. 185-207
    • Young, R.H.1    Clement, P.B.2
  • 9
    • 34247511497 scopus 로고    scopus 로고
    • LKB1 and SAD kinases define a pathway required for the polarization of cortical neurons
    • Barnes AP, Lilley BN, Pan YA, et al. LKB1 and SAD kinases define a pathway required for the polarization of cortical neurons. Cell 2007;129:549-63.
    • (2007) Cell , vol.129 , pp. 549-563
    • Barnes, A.P.1    Lilley, B.N.2    Pan, Y.A.3
  • 10
    • 1542777034 scopus 로고    scopus 로고
    • Complete polarization of single intestinal epithelial cells upon activation of LKB1 by STRAD
    • Baas AF, Kuipers J, van der Wel NN, et al. Complete polarization of single intestinal epithelial cells upon activation of LKB1 by STRAD. Cell 2004;116:457-66.
    • (2004) Cell , vol.116 , pp. 457-466
    • Baas, A.F.1    Kuipers, J.2    van der Wel, N.N.3
  • 11
    • 3042649049 scopus 로고    scopus 로고
    • LKB1 kinase: Master and commander of metabolism and polarity
    • Spicer J, Ashworth A. LKB1 kinase: master and commander of metabolism and polarity. Curr Biol 2004;14:R383-5.
    • (2004) Curr Biol , vol.14
    • Spicer, J.1    Ashworth, A.2
  • 12
    • 0036580830 scopus 로고    scopus 로고
    • Endometrioid carcinoma of the uterine corpus: A review of its pathology with emphasis on recent advances and problematic aspects
    • Clement PB, Young RH. Endometrioid carcinoma of the uterine corpus: a review of its pathology with emphasis on recent advances and problematic aspects. Adv Anat Pathol 2002;9:145-84.
    • (2002) Adv Anat Pathol , vol.9 , pp. 145-184
    • Clement, P.B.1    Young, R.H.2
  • 13
    • 0345167800 scopus 로고    scopus 로고
    • TSC2 mediates cellular energy response to control cell growth and survival
    • Inoki K, Zhu T, Guan KL. TSC2 mediates cellular energy response to control cell growth and survival. Cell 2003;115:577-90.
    • (2003) Cell , vol.115 , pp. 577-590
    • Inoki, K.1    Zhu, T.2    Guan, K.L.3
  • 15
    • 33751204464 scopus 로고    scopus 로고
    • AMP-activated protein kinase regulates the assembly of epithelial tight junctions
    • Zhang L, Li J, Young LH, Caplan MJ. AMP-activated protein kinase regulates the assembly of epithelial tight junctions. Proc Natl Acad Sci U S A 2006;103:17272-7.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 17272-17277
    • Zhang, L.1    Li, J.2    Young, L.H.3    Caplan, M.J.4
  • 16
    • 33846521353 scopus 로고    scopus 로고
    • Regulation of epithelial tight junction assembly and disassembly by AMP-activated protein kinase
    • Zheng B, Cantley LC. Regulation of epithelial tight junction assembly and disassembly by AMP-activated protein kinase. Proc Natl Acad Sci U S A 2007;104:819-22.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 819-822
    • Zheng, B.1    Cantley, L.C.2
  • 17
    • 12144287284 scopus 로고    scopus 로고
    • LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1
    • Lizcano JM, Goransson O, Toth R, et al. LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1. EMBO J 2004;23:833-43.
    • (2004) EMBO J , vol.23 , pp. 833-843
    • Lizcano, J.M.1    Goransson, O.2    Toth, R.3
  • 18
    • 0037068461 scopus 로고    scopus 로고
    • Loss of the Lkb1 tumour suppressor provokes intestinal polyposis but resistance to transformation
    • Bardeesy N, Sinha M, Hezel AF, et al. Loss of the Lkb1 tumour suppressor provokes intestinal polyposis but resistance to transformation. Nature 2002;419:162-7.
    • (2002) Nature , vol.419 , pp. 162-167
    • Bardeesy, N.1    Sinha, M.2    Hezel, A.F.3
  • 19
    • 4444366945 scopus 로고    scopus 로고
    • In vivo adenovirus-mediated gene transduction into mouse endometrial glands: A novel tool to model endometrial cancer in the mouse
    • Beauparlant SL, Read PW, Di Cristofano A. In vivo adenovirus-mediated gene transduction into mouse endometrial glands: a novel tool to model endometrial cancer in the mouse. Gynecol Oncol 2004;94:713-8.
    • (2004) Gynecol Oncol , vol.94 , pp. 713-718
    • Beauparlant, S.L.1    Read, P.W.2    Di Cristofano, A.3
  • 20
    • 35048871112 scopus 로고    scopus 로고
    • Genomewide discovery and classification of candidate ovarian fertility genes in the mouse
    • Gallardo TD, John GB, Shirley L, et al. Genomewide discovery and classification of candidate ovarian fertility genes in the mouse. Genetics 2007;177:179-94.
    • (2007) Genetics , vol.177 , pp. 179-194
    • Gallardo, T.D.1    John, G.B.2    Shirley, L.3
  • 21
    • 0021141541 scopus 로고
    • In vitro analysis of multistage epidermal carcinogenesis: Development of indefinite renewal capacity and reduced growth factor requirements in colony forming keratinocytes precedes malignant transformation
    • Pera MF, Gorman PA. In vitro analysis of multistage epidermal carcinogenesis: development of indefinite renewal capacity and reduced growth factor requirements in colony forming keratinocytes precedes malignant transformation. Carcinogenesis 1984;5:671-82.
    • (1984) Carcinogenesis , vol.5 , pp. 671-682
    • Pera, M.F.1    Gorman, P.A.2
  • 22
    • 3142594193 scopus 로고    scopus 로고
    • The LKB1 tumor suppressor negatively regulates mTOR signaling
    • Shaw RJ, Bardeesy N, Manning BD, et al. The LKB1 tumor suppressor negatively regulates mTOR signaling. Cancer Cell 2004;6:91-9.
    • (2004) Cancer Cell , vol.6 , pp. 91-99
    • Shaw, R.J.1    Bardeesy, N.2    Manning, B.D.3
  • 23
    • 0037844887 scopus 로고    scopus 로고
    • Mitotic regulation of ribosomal S6 kinase 1 involves Ser/Thr, Pro phosphorylation of consensus and non-consensus sites by Cdc2
    • Shah OJ, Ghosh S, Hunter T. Mitotic regulation of ribosomal S6 kinase 1 involves Ser/Thr, Pro phosphorylation of consensus and non-consensus sites by Cdc2. J Biol Chem 2003;278:16433-42.
    • (2003) J Biol Chem , vol.278 , pp. 16433-16442
    • Shah, O.J.1    Ghosh, S.2    Hunter, T.3
  • 24
    • 33846526691 scopus 로고    scopus 로고
    • Immunolocalization of phospho-S6 kinases: A new way to detect mitosis in tissue sections and in cell culture
    • Schmidt T, Wahl P, Wuthrich RP, et al. Immunolocalization of phospho-S6 kinases: a new way to detect mitosis in tissue sections and in cell culture. Histochem Cell Biol 2007;127:123-9.
    • (2007) Histochem Cell Biol , vol.127 , pp. 123-129
    • Schmidt, T.1    Wahl, P.2    Wuthrich, R.P.3
  • 25
    • 0025322773 scopus 로고
    • Effects of substrata on the polarization of bovine endometrial epithelial cells in vitro
    • Munson L, Wilkinson JE, Schlafer DH. Effects of substrata on the polarization of bovine endometrial epithelial cells in vitro. Cell Tissue Res 1990;261:155-61.
    • (1990) Cell Tissue Res , vol.261 , pp. 155-161
    • Munson, L.1    Wilkinson, J.E.2    Schlafer, D.H.3
  • 27
    • 0036112627 scopus 로고    scopus 로고
    • DNA mismatch repair deficiency accelerates endometrial tumorigenesis in Pten heterozygous mice
    • Wang H, Douglas W, Lia M, et al. DNA mismatch repair deficiency accelerates endometrial tumorigenesis in Pten heterozygous mice. Am J Pathol 2002;160:1481-6.
    • (2002) Am J Pathol , vol.160 , pp. 1481-1486
    • Wang, H.1    Douglas, W.2    Lia, M.3
  • 28
    • 0037022364 scopus 로고    scopus 로고
    • Genetic analysis of Pten and Ink4a/Arf interactions in the suppression of tumorigenesis in mice
    • You MJ, Castrillon DH, Bastian BC, et al. Genetic analysis of Pten and Ink4a/Arf interactions in the suppression of tumorigenesis in mice. Proc Natl Acad Sci U S A 2002;99:1455-60.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 1455-1460
    • You, M.J.1    Castrillon, D.H.2    Bastian, B.C.3
  • 29
    • 13044250465 scopus 로고    scopus 로고
    • Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems
    • Podsypanina K, Ellenson LH, Nemes A, et al. Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems. Proc Natl Acad Sci U S A 1999;96:1563-8.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 1563-1568
    • Podsypanina, K.1    Ellenson, L.H.2    Nemes, A.3
  • 30
  • 32
    • 34547926839 scopus 로고    scopus 로고
    • LKB1 modulates lung cancer differentiation and metastasis
    • Ji H, Ramsey MR, Hayes DN, et al. LKB1 modulates lung cancer differentiation and metastasis. Nature 2007;448:807-10.
    • (2007) Nature , vol.448 , pp. 807-810
    • Ji, H.1    Ramsey, M.R.2    Hayes, D.N.3
  • 33
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000;100:57-70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 34
    • 0037444766 scopus 로고    scopus 로고
    • Heat-shock protein 90 and Cdc37 interact with LKB1 and regulate its stability
    • Boudeau J, Deak M, Lawlor MA, Morrice NA, Alessi DR. Heat-shock protein 90 and Cdc37 interact with LKB1 and regulate its stability. Biochem J 2003;370:849-57.
    • (2003) Biochem J , vol.370 , pp. 849-857
    • Boudeau, J.1    Deak, M.2    Lawlor, M.A.3    Morrice, N.A.4    Alessi, D.R.5


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