Mitochondrial respiration defects modulate differentiation but not proliferation of hematopoietic stem and progenitor cells

FEBS Letters

Volumn 584, Issue 15, 2010, Pages 3402-3409

  Inoue, Shin Ichi ^a,b   Noda, Shinichi ^a,b   Kashima, Koutarou ^a,b   Nakada, Kazuto ^b   Hayashi, Jun Ichi ^b   Miyoshi, Hiroyuki ^a  

^a RIKEN BIORESOURCE CENTER   (Japan)

^b UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

ATP; Hematopoiesis; Hematopoietic stem cell; Mitochondria; Progenitor

Indexed keywords

ADENOSINE TRIPHOSPHATE; COLONY STIMULATING FACTOR RECEPTOR; MITOCHONDRIAL DNA; MYELOPEROXIDASE; NOTCH1 RECEPTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR GATA 3;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BONE MARROW TRANSPLANTATION; CELL COUNT; CELL DIFFERENTIATION; CELL LINEAGE; CELL POPULATION; CELL PROLIFERATION; CONTROLLED STUDY; DISEASE MODEL; DISORDERS OF MITOCHONDRIAL FUNCTIONS; HEMATOPOIETIC STEM CELL; MITOCHONDRIAL RESPIRATION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; STEM CELL;

ADENOSINE TRIPHOSPHATE; ANIMALS; APOPTOSIS; BONE MARROW CELLS; CELL CYCLE; CELL DIFFERENTIATION; CELL LINEAGE; CELL PROLIFERATION; CELL RESPIRATION; DNA, MITOCHONDRIAL; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEMATOPOIESIS; HEMATOPOIETIC STEM CELLS; MICE; MITOCHONDRIA; REACTIVE OXYGEN SPECIES;

EID: 77955273858     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2010.06.036     Document Type: Article

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