-
1
-
-
34248576759
-
Physiology and pathophysiology of purinergic neurotransmission
-
DOI 10.1152/physrev.00043.2006
-
Burnstock G. Physiology and pathophysiology of purinergic neurotransmission. Physiol Rev. 2007;87:659-797. (Pubitemid 47084682)
-
(2007)
Physiological Reviews
, vol.87
, Issue.2
, pp. 659-797
-
-
Burnstock, G.1
-
3
-
-
0036118418
-
Purinergic signaling and vascular cell proliferation and death
-
DOI 10.1161/hq0302.105360
-
Burnstock G. Purinergic signaling and vascular cell proliferation and death. Arterioscler Thromb Vasc Biol. 2002;22:364-73. (Pubitemid 34218740)
-
(2002)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.22
, Issue.3
, pp. 364-373
-
-
Burnstock, G.1
-
4
-
-
0031754497
-
Receptors for purines and pyrimidines
-
Ralevic V, Burnstock G. Receptors for purines and pyrimidines. Pharmacol Rev. 1998;50:413-92. (Pubitemid 28477681)
-
(1998)
Pharmacological Reviews
, vol.50
, Issue.3
, pp. 413-492
-
-
Ralevic, V.1
Burnstock, G.2
-
5
-
-
0141457730
-
Mechanisms of release of nucleotides and integration of their action as P2X- and P2Y-receptor activating molecules
-
DOI 10.1124/mol.64.4.785
-
Lazarowski ER, Boucher RC, Harden TK. Mechanisms of release of nucleotides and integration of their action as P2X- and P2Y-receptor activating molecules. Mol Pharmacol. 2003;64:785-95. (Pubitemid 37153046)
-
(2003)
Molecular Pharmacology
, vol.64
, Issue.4
, pp. 785-795
-
-
Lazarowski, E.R.1
Boucher, R.C.2
Harden, T.K.3
-
7
-
-
0036788971
-
Molecular physiology of P2X receptors
-
North R. Molecular physiology of P2X receptors. Physiol Rev. 2002;82:1013-67.
-
(2002)
Physiol Rev
, vol.82
, pp. 1013-1067
-
-
North, R.1
-
8
-
-
66249138835
-
Antagonists of the P2X(7) receptor. From lead identification to drug development
-
Guile S, Alcaraz L, Birkinshaw T, Bowers K, Ebden M, Furber M, Stocks M. Antagonists of the P2X(7) receptor. From lead identification to drug development. J Med Chem. 2009;52:3123-41.
-
(2009)
J Med Chem
, vol.52
, pp. 3123-3141
-
-
Guile, S.1
Alcaraz, L.2
Birkinshaw, T.3
Bowers, K.4
Ebden, M.5
Furber, M.6
Stocks, M.7
-
9
-
-
77950635286
-
Basic principles of platelet biology and clinical implications
-
Angiolillo D, Ueno M, Goto S. Basic principles of platelet biology and clinical implications. Circ J. 2010;74:597-607.
-
(2010)
Circ J
, vol.74
, pp. 597-607
-
-
Angiolillo, D.1
Ueno, M.2
Goto, S.3
-
10
-
-
79952048493
-
Ticagrelor: An investigational oral antiplatelet treatment for reduction of major adverse cardiac events in patients with acute coronary syndrome
-
Abergel E, Nikolsky E. Ticagrelor: an investigational oral antiplatelet treatment for reduction of major adverse cardiac events in patients with acute coronary syndrome. Vasc Health Risk Manag. 2010;6:963-77.
-
(2010)
Vasc Health Risk Manag
, vol.6
, pp. 963-977
-
-
Abergel, E.1
Nikolsky, E.2
-
11
-
-
77951590103
-
P2X purinergic receptor ligands: Recently patented compounds
-
Gunosewoyo H, Kassiou M. P2X purinergic receptor ligands: recently patented compounds. Expert Opin Ther Pat. 2010;20:625-46.
-
(2010)
Expert Opin Ther Pat
, vol.20
, pp. 625-646
-
-
Gunosewoyo, H.1
Kassiou, M.2
-
12
-
-
67349098560
-
Cell signaling via the P2X(7) nucleotide receptor: Linkage to ROS production, gene transcription, and receptor trafficking
-
Lenertz LY, Gavala M, Hill LM, Bertics PJ. Cell signaling via the P2X(7) nucleotide receptor: linkage to ROS production, gene transcription, and receptor trafficking. Purinergic Signal. 2009;5:175-87.
-
(2009)
Purinergic Signal
, vol.5
, pp. 175-187
-
-
Lenertz, L.Y.1
Gavala, M.2
Hill, L.M.3
Bertics, P.J.4
-
13
-
-
77953106276
-
Mutation of putative N-linked glycosylation sites on the human nucleotide receptor P2X(7) reveals a key residue important for receptor function
-
Lenertz LY, Wang Z, Guadarrama AG, Hill LM, Gavala ML, Bertics PJ. Mutation of putative N-linked glycosylation sites on the human nucleotide receptor P2X(7) reveals a key residue important for receptor function. Biochemistry. 2010;49:4611-9.
-
(2010)
Biochemistry
, vol.49
, pp. 4611-4619
-
-
Lenertz, L.Y.1
Wang, Z.2
Guadarrama, A.G.3
Hill, L.M.4
Gavala, M.L.5
Bertics, P.J.6
-
14
-
-
67649395964
-
Analysis of assembly and trafficking of native P2X4 and P2X7 receptor complexes in rodent immune cells
-
Boumechache M, Masin M, Edwardson J, Górecki D, Murrell- Lagnado R. Analysis of assembly and trafficking of native P2X4 and P2X7 receptor complexes in rodent immune cells. J Biol Chem. 2009;284:13446-54.
-
(2009)
J Biol Chem
, vol.284
, pp. 13446-13454
-
-
Boumechache, M.1
Masin, M.2
Edwardson, J.3
Górecki, D.4
Murrell-Lagnado, R.5
-
15
-
-
0036659510
-
Modulation of monocyte signaling and pore formation in response to agonists of the nucleotide receptor P2X(7)
-
Aga M, Johnson CJ, Hart AP, Guadarrama AG, Suresh M, Svaren J, Bertics PJ, Darien BJ. Modulation of monocyte signaling and pore formation in response to agonists of the nucleotide receptor P2X(7). J Leukoc Biol. 2002;72:222-32.
-
(2002)
J Leukoc Biol
, vol.72
, pp. 222-232
-
-
Aga, M.1
Johnson, C.J.2
Hart, A.P.3
Guadarrama, A.G.4
Suresh, M.5
Svaren, J.6
Bertics, P.J.7
Darien, B.J.8
-
16
-
-
67349232457
-
Different properties of P2X(7) receptor in hippocampal and cortical astrocytes
-
Bianco F, Colombo A, Saglietti L, Lecca D, Abbracchio M, Matteoli M, Verderio C. Different properties of P2X(7) receptor in hippocampal and cortical astrocytes. Purinergic Signal. 2009;5: 233-40.
-
(2009)
Purinergic Signal
, vol.5
, pp. 233-240
-
-
Bianco, F.1
Colombo, A.2
Saglietti, L.3
Lecca, D.4
Abbracchio, M.5
Matteoli, M.6
Verderio, C.7
-
17
-
-
67349186489
-
Expression, signaling, and function of P2X7 receptors in bone
-
Grol MW, Panupinthu N, Korcok J, Sims SM, Dixon SJ. Expression, signaling, and function of P2X7 receptors in bone. Purinergic Signal. 2009;5:205-21.
-
(2009)
Purinergic Signal
, vol.5
, pp. 205-221
-
-
Grol, M.W.1
Panupinthu, N.2
Korcok, J.3
Sims, S.M.4
Dixon, S.J.5
-
18
-
-
77953503071
-
Involvement of spinal microglial P2X7 receptor in generation of tolerance to morphine analgesia in rats
-
Zhou D, Chen ML, Zhang YQ, Zhao ZQ. Involvement of spinal microglial P2X7 receptor in generation of tolerance to morphine analgesia in rats. J Neurosci. 2010;30:8042-7.
-
(2010)
J Neurosci
, vol.30
, pp. 8042-8047
-
-
Zhou, D.1
Chen, M.L.2
Zhang, Y.Q.3
Zhao, Z.Q.4
-
19
-
-
0031201476
-
Extracellular ATP Triggers IL-1beta Release by Activating the Purinergic P2Z Receptor of Human Macrophages
-
Ferrari D, Chiozzi P, Falzoni S, Dal Susino M, Melchiorri L, Baricordi O, Di Virgilio F. Extracellular ATP triggers IL-1 beta release by activating the purinergic P2Z receptor of human macrophages. J Immunol. 1997;159:1451-8. (Pubitemid 127484125)
-
(1997)
Journal of Immunology
, vol.159
, Issue.3
, pp. 1451-1458
-
-
Ferrari, D.1
Chiozzi, P.2
Falzoni, S.3
Dal, S.M.4
Melchiorri, L.5
Baricordi, O.R.6
Di, V.F.7
-
20
-
-
77958532672
-
Activation of the transcription factor FosB/activating protein-1 (AP-1) is a prominent downstream signal of the extracellular nucleotide receptor P2RX7 in monocytic and osteoblastic cells
-
Gavala ML, Hill LM, Lenertz LY, Karta MR, Bertics PJ. Activation of the transcription factor FosB/activating protein-1 (AP-1) is a prominent downstream signal of the extracellular nucleotide receptor P2RX7 in monocytic and osteoblastic cells. J Biol Chem. 2010;285:34288-98.
-
(2010)
J Biol Chem
, vol.285
, pp. 34288-34298
-
-
Gavala, M.L.1
Hill, L.M.2
Lenertz, L.Y.3
Karta, M.R.4
Bertics, P.J.5
-
21
-
-
78049404838
-
Extracellular ATP may contribute to tissue repair by rapidly stimulating purinergic receptor X7-dependent vascular endothelial growth factor release from primary human monocytes
-
Hill LM, Gavala ML, Lenertz LY, Bertics PJ. Extracellular ATP may contribute to tissue repair by rapidly stimulating purinergic receptor X7-dependent vascular endothelial growth factor release from primary human monocytes. J Immunol. 2010;185: 3028-34.
-
(2010)
J Immunol
, vol.185
, pp. 3028-3034
-
-
Hill, L.M.1
Gavala, M.L.2
Lenertz, L.Y.3
Bertics, P.J.4
-
22
-
-
0035808396
-
7 receptors
-
DOI 10.1074/jbc.M006781200
-
Solle M, Labasi J, Perregaux DG, Stam E, Petrushova N, Koller BH, Griffiths RJ, Gabel CA. Altered cytokine production in mice lacking P2X7 receptors. J Biol Chem. 2001;276:125-32. (Pubitemid 32050297)
-
(2001)
Journal of Biological Chemistry
, vol.276
, Issue.1
, pp. 125-132
-
-
Solle, M.1
Labasi, J.2
Perregaux, D.G.3
Stam, E.4
Petrushova, N.5
Koller, B.H.6
Griffiths, R.J.7
Gabel, C.A.8
-
23
-
-
0035881559
-
7 contains multiple protein- and lipid-interaction motifs including a potential binding site for bacterial lipopolysaccharide
-
Denlinger LC, Fisette PL, Sommer JA, Watters JJ, Prabhu U, Dubyak GR, Proctor RA, Bertics PJ. The nucleotide receptor P2X7 contains multiple protein- and lipid-interaction motifs including a potential binding site for bacterial lipopolysaccharide. J Immunol. 2001;167:1871-6. (Pubitemid 32747489)
-
(2001)
Journal of Immunology
, vol.167
, Issue.4
, pp. 1871-1876
-
-
Denlinger, L.C.1
Fisette, P.L.2
Sommer, J.A.3
Watters, J.J.4
Prabhu, U.5
Dubyak, G.R.6
Proctor, R.A.7
Bertics, P.J.8
-
24
-
-
67349124829
-
Genetics of the P2X7 receptor and human disease
-
Fuller S, Stokes L, Skarratt K, Gu B, Wiley JS. Genetics of the P2X7 receptor and human disease. Purinergic Signal. 2009;5: 257-62.
-
(2009)
Purinergic Signal
, vol.5
, pp. 257-262
-
-
Fuller, S.1
Stokes, L.2
Skarratt, K.3
Gu, B.4
Wiley, J.S.5
-
25
-
-
0037424417
-
P2X7 receptor cell surface expression and cytolytic pore formation are regulated by a distal C-terminal region
-
Smart M, Gu B, Panchal R, Wiley J, Cromer B, Williams D, Petrou S. P2X7 receptor cell surface expression and cytolytic pore formation are regulated by a distal C-terminal region. J Biol Chem. 2003;278:8853-60.
-
(2003)
J Biol Chem
, vol.278
, pp. 8853-8860
-
-
Smart, M.1
Gu, B.2
Panchal, R.3
Wiley, J.4
Cromer, B.5
Williams, D.6
Petrou, S.7
-
26
-
-
0041845127
-
7 nucleotide receptor results in trafficking defects and impaired function
-
Denlinger LC, Sommer JA, Parker K, Gudipaty L, Fisette PL, Watters JJ, Proctor RA, Dubyak GR, Bertics PJ. Mutation of a dibasic amino acid motif within the C terminus of the P2X7 nucleotide receptor results in trafficking defects and impaired function. J Immunol. 2003;171:1304-11. (Pubitemid 36900061)
-
(2003)
Journal of Immunology
, vol.171
, Issue.3
, pp. 1304-1311
-
-
Denlinger, L.C.1
Sommer, J.A.2
Parker, K.3
Gudipaty, L.4
Fisette, P.L.5
Watters, J.W.6
Proctor, R.A.7
Dubyak, G.R.8
Bertics, P.J.9
-
27
-
-
77950941000
-
Single nucleotide polymorphisms that were identified in affective mood disorders affect ATPactivated P2X(7) receptor functions
-
Roger S, Mei ZZ, Baldwin JM, Dong L, Bradley H, Baldwin SA, Surprenant A, Jiang LH. Single nucleotide polymorphisms that were identified in affective mood disorders affect ATPactivated P2X(7) receptor functions. J Psychiatr Res. 2009;44: 347-55.
-
(2009)
J Psychiatr Res
, vol.44
, pp. 347-355
-
-
Roger, S.1
Mei, Z.Z.2
Baldwin, J.M.3
Dong, L.4
Bradley, H.5
Baldwin, S.A.6
Surprenant, A.7
Jiang, L.H.8
-
28
-
-
61449242774
-
Palmitoylation of the P2X7 receptor, an ATP-gated channel, controls its expression and association with lipid rafts
-
Gonnord P, Delarasse C, Auger R, Benihoud K, Prigent M, Cuif M, Lamaze C, Kanellopoulos J. Palmitoylation of the P2X7 receptor, an ATP-gated channel, controls its expression and association with lipid rafts. FASEB J. 2009;23:795-805.
-
(2009)
FASEB J
, vol.23
, pp. 795-805
-
-
Gonnord, P.1
Delarasse, C.2
Auger, R.3
Benihoud, K.4
Prigent, M.5
Cuif, M.6
Lamaze, C.7
Kanellopoulos, J.8
-
29
-
-
66249107019
-
Direct observation of ATP-induced conformational changes in single P2X4 receptors
-
Shinozaki Y, Sumitomo K, Tsuda M, Koizumi S, Inoue K, Torimitsu K. Direct observation of ATP-induced conformational changes in single P2X4 receptors. PLoS Biol. 2009;7:e103.
-
(2009)
PLoS Biol
, vol.7
-
-
Shinozaki, Y.1
Sumitomo, K.2
Tsuda, M.3
Koizumi, S.4
Inoue, K.5
Torimitsu, K.6
-
30
-
-
54249161058
-
The nucleotide receptor P2RX7 mediates ATP-induced CREB activation in human and murine monocytic cells
-
Gavala ML, Pfeiffer ZA, Bertics PJ. The nucleotide receptor P2RX7 mediates ATP-induced CREB activation in human and murine monocytic cells. J Leukoc Biol. 2008;84:1159-71.
-
(2008)
J Leukoc Biol
, vol.84
, pp. 1159-1171
-
-
Gavala, M.L.1
Pfeiffer, Z.A.2
Bertics, P.J.3
-
31
-
-
60749087353
-
Attenuated P2X7 pore function as a risk factor for virus-induced loss of asthma control
-
Denlinger LC, Shi L, Guadarrama AG, Schell K, Green D, Morrin A, Hogan K, Sorkness R, Busse WW, Gern JE. Attenuated P2X7 pore function as a risk factor for virus-induced loss of asthma control. Am J Respir Crit Care Med. 2009;179: 265-70.
-
(2009)
Am J Respir Crit Care Med
, vol.179
, pp. 265-270
-
-
Denlinger, L.C.1
Shi, L.2
Guadarrama, A.G.3
Schell, K.4
Green, D.5
Morrin, A.6
Hogan, K.7
Sorkness, R.8
Busse, W.W.9
Gern, J.E.10
-
32
-
-
59749093364
-
1513AC polymorphism in the P2X7 receptor gene in patients with papillary thyroid cancer: Correlation with histological variants and clinical parameters
-
Dardano A, Falzoni S, Caraccio N, Polini A, Tognini S, Solini A, Berti P, Di Virgilio F, Monzani F. 1513A[C polymorphism in the P2X7 receptor gene in patients with papillary thyroid cancer: correlation with histological variants and clinical parameters. J Clin Endocrinol Metab. 2009;94:695-8.
-
(2009)
J Clin Endocrinol Metab
, vol.94
, pp. 695-698
-
-
Dardano, A.1
Falzoni, S.2
Caraccio, N.3
Polini, A.4
Tognini, S.5
Solini, A.6
Berti, P.7
Di Virgilio, F.8
Monzani, F.9
-
33
-
-
37549030561
-
Increased P2X7 receptor expression and function in thyroid papillary cancer: A new potential marker of the disease?
-
Solini A, Cuccato S, Ferrari D, Santini E, Gulinelli S, Callegari M, Dardano A, Faviana P, Madec S, Di Virgilio F, Monzani F. Increased P2X7 receptor expression and function in thyroid papillary cancer: a new potential marker of the disease? Endocrinology. 2008;149:389-96.
-
(2008)
Endocrinology
, vol.149
, pp. 389-396
-
-
Solini, A.1
Cuccato, S.2
Ferrari, D.3
Santini, E.4
Gulinelli, S.5
Callegari, M.6
Dardano, A.7
Faviana, P.8
Madec, S.9
Di Virgilio, F.10
Monzani, F.11
-
34
-
-
4043079197
-
P2X7 receptor inhibition improves recovery after spinal cord injury
-
DOI 10.1038/nm1082
-
Wang X, Arcuino G, Takano T, Lin J, Peng W, Wan P, Li P, Xu Q, Liu Q, Goldman S, Nedergaard M. P2X7 receptor inhibition improves recovery after spinal cord injury. Nat Med. 2004;10: 821-7. (Pubitemid 39070855)
-
(2004)
Nature Medicine
, vol.10
, Issue.8
, pp. 821-827
-
-
Wang, X.1
Arcuino, G.2
Takano, T.3
Lin, J.4
Peng, W.G.5
Wan, P.6
Li, P.7
Xu, Q.8
Liu, Q.S.9
Goldman, S.A.10
Nedergaard, M.11
-
35
-
-
68149157440
-
Systemic administration of an antagonist of the ATP-sensitive receptor P2X7 improves recovery after spinal cord injury
-
Peng W, Cotrina M, Han X, Yu H, Bekar L, Blum L, Takano T, Tian G, Goldman S, Nedergaard M. Systemic administration of an antagonist of the ATP-sensitive receptor P2X7 improves recovery after spinal cord injury. Proc Natl Acad Sci USA. 2009; 106:12489-93.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 12489-12493
-
-
Peng, W.1
Cotrina, M.2
Han, X.3
Yu, H.4
Bekar, L.5
Blum, L.6
Takano, T.7
Tian, G.8
Goldman, S.9
Nedergaard, M.10
-
36
-
-
0037135302
-
2Z/P2X7 antagonist, oxidized ATP, in arthritic rats
-
DOI 10.1016/S0304-3940(02)00385-3, PII S0304394002003853
-
Dell'Antonio G, Quattrini A, Dal Cin E, Fulgenzi A, Ferrero M. Antinociceptive effect of a new P(2Z)/P2X7 antagonist, oxidized ATP, in arthritic rats. Neurosci Lett. 2002;327:87-90. (Pubitemid 34722414)
-
(2002)
Neuroscience Letters
, vol.327
, Issue.2
, pp. 87-90
-
-
Dell'Antonio, G.1
Quattrini, A.2
Dal, C.E.3
Fulgenzi, A.4
Ferrero, M.E.5
-
37
-
-
57349085122
-
Characterization of N-(adamantan-1- ylmethyl)-5-[(3R-amino-pyrrolidin-1- yl)methyl]-2-chloro-benzamide, a P2X7 antagonist in animal models of pain and inflammation
-
Broom D, Matson D, Bradshaw E, Buck M, Meade R, Coombs S, Matchett M, Ford K, Yu W, Yuan J, Sun S, Ochoa R, Krause J, Wustrow D, Cortright D. Characterization of N-(adamantan-1- ylmethyl)-5-[(3R-amino-pyrrolidin-1-yl) methyl]-2-chloro-benzamide, a P2X7 antagonist in animal models of pain and inflammation. J Pharmacol Exp Ther. 2008;327:620-33.
-
(2008)
J Pharmacol Exp Ther
, vol.327
, pp. 620-633
-
-
Broom, D.1
Matson, D.2
Bradshaw, E.3
Buck, M.4
Meade, R.5
Coombs, S.6
Matchett, M.7
Ford, K.8
Yu, W.9
Yuan, J.10
Sun, S.11
Ochoa, R.12
Krause, J.13
Wustrow, D.14
Cortright, D.15
-
38
-
-
0036899591
-
Relief of inflammatory pain in rats by local use of the selective P2X7 ATP receptor inhibitor, oxidized ATP
-
DOI 10.1002/art.10678
-
Dell'Antonio G, Quattrini A, Cin E, Fulgenzi A, Ferrero M. Relief of inflammatory pain in rats by local use of the selective P2X7 ATP receptor inhibitor, oxidized ATP. Arthritis Rheum. 2002;46:3378-85. (Pubitemid 35453550)
-
(2002)
Arthritis and Rheumatism
, vol.46
, Issue.12
, pp. 3378-3385
-
-
Dell'Antonio, G.1
Quattrini, A.2
Dal, C.E.3
Fulgenzi, A.4
Ferrero, M.E.5
-
39
-
-
0037634326
-
7 nucleotide receptor reveals its regulatory roles in bone formation and resorption
-
DOI 10.1210/me.2003-0021
-
Ke H, Qi H, Weidema A, Zhang Q, Panupinthu N, Crawford D, Grasser W, Paralkar V, Li M, Audoly L, Gabel C, Jee W, Dixon S, Sims S, Thompson D. Deletion of the P2X7 nucleotide receptor reveals its regulatory roles in bone formation and resorption. Mol Endocrinol. 2003;17:1356-67. (Pubitemid 36819956)
-
(2003)
Molecular Endocrinology
, vol.17
, Issue.7
, pp. 1356-1367
-
-
Ke, H.Z.1
Qi, H.2
Weidema, A.F.3
Zhang, Q.4
Panupinthu, N.5
Crawford, D.T.6
Grasser, W.A.7
Paralkar, V.M.8
Li, M.9
Audoly, L.P.10
Gabel, C.A.11
Jee, W.S.S.12
Dixon, S.J.13
Sims, S.M.14
Thompson, D.D.15
-
40
-
-
30044443068
-
The P2X7 nucleotide receptor mediates skeletal mechanotransduction
-
Li J, Liu D, Ke HZ, Duncan RL, Turner CH. The P2X7 nucleotide receptor mediates skeletal mechanotransduction. J Biol Chem. 2005;280:42952-9.
-
(2005)
J Biol Chem
, vol.280
, pp. 42952-42959
-
-
Li, J.1
Liu, D.2
Ke, H.Z.3
Duncan, R.L.4
Turner, C.H.5
-
41
-
-
0035930941
-
Mechanically induced ATP release from human osteoblastic cells
-
DOI 10.1006/bbrc.2001.6124
-
Romanello M, Pani B, Bicego MD, Andrea P. Mechanically induced ATP release from human osteoblastic cells. Biochem Biophys Res Commun. 2001;289:1275-81. (Pubitemid 34076330)
-
(2001)
Biochemical and Biophysical Research Communications
, vol.289
, Issue.5
, pp. 1275-1281
-
-
Romanello, M.1
Pani, B.2
Bicego, M.3
D'Andrea, P.4
-
42
-
-
0041709201
-
Release and interconversion of P2 receptor agonists by human osteoblast-like cells
-
DOI 10.1096/fj.02-0940com
-
Buckley KA, Golding SL, Rice JM, Dillon JP, Gallagher JA. Release and interconversion of P2 receptor agonists by human osteoblast-like cells. FASEB J. 2003;17:1401-10. (Pubitemid 36935655)
-
(2003)
FASEB Journal
, vol.17
, Issue.11
, pp. 1401-1410
-
-
Buckley, K.A.1
Golding, S.L.2
Rice, J.M.3
Dillon, J.P.4
Gallagher, J.A.5
-
43
-
-
77952305210
-
Extracellular adenosine triphosphate and chronic obstructive pulmonary disease
-
Lommatzsch M, Cicko S, Müller T, Lucattelli M, Bratke K, Stoll P, Grimm M, Dürk T, Zissel G, Ferrari D, Di Virgilio F, Sorichter S, Lungarella G, Virchow J, Idzko M. Extracellular adenosine triphosphate and chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2010;181:928-34.
-
(2010)
Am J Respir Crit Care Med
, vol.181
, pp. 928-934
-
-
Lommatzsch, M.1
Cicko, S.2
Müller, T.3
Lucattelli, M.4
Bratke, K.5
Stoll, P.6
Grimm, M.7
Dürk, T.8
Zissel, G.9
Ferrari, D.10
Di Virgilio, F.11
Sorichter, S.12
Lungarella, G.13
Virchow, J.14
Idzko, M.15
-
44
-
-
79952218099
-
P2X7 receptor signalling in the pathogenesis of smoke-induced lung inflammation and emphysema
-
Lucattelli M, Cicko S, Müller T, Lommatzsch M, de Cunto G, Cardini S, Sundas W, Grimm M, Zeiser R, Dürk T, Zissel G, Sorichter S, Ferrari D, Di Virgilio F, Virchow J, Lungarella G, Idzko M: P2X7 receptor signalling in the pathogenesis of smoke-induced lung inflammation and emphysema. Am J Respir Cell Mol Biol 2010.
-
(2010)
Am J Respir Cell Mol Biol
-
-
Lucattelli, M.1
Cicko, S.2
Müller, T.3
Lommatzsch, M.4
De Cunto, G.5
Cardini, S.6
Sundas, W.7
Grimm, M.8
Zeiser, R.9
Dürk, T.10
Zissel, G.11
Sorichter, S.12
Ferrari, D.13
Di Virgilio, F.14
Virchow, J.15
Lungarella, G.16
Idzko, M.17
-
45
-
-
20144375454
-
7 purinoceptor gene abolishes chronic inflammatory and neuropathic pain
-
DOI 10.1016/j.pain.2005.01.002
-
Chessell I, Hatcher J, Bountra C, Michel A, Hughes J, Green P, Egerton J, Murfin M, Richardson J, Peck W, Grahames C, Casula M, Yiangou Y, Birch R, Anand P, Buell G. Disruption of the P2X7 purinoceptor gene abolishes chronic inflammatory and neuropathic pain. Pain. 2005;114:386-96. (Pubitemid 40385877)
-
(2005)
Pain
, vol.114
, Issue.3
, pp. 386-396
-
-
Chessell, I.P.1
Hatcher, J.P.2
Bountra, C.3
Michel, A.D.4
Hughes, J.P.5
Green, P.6
Egerton, J.7
Murfin, M.8
Richardson, J.9
Peck, W.L.10
Grahames, C.B.A.11
Casula, M.A.12
Yiangou, Y.13
Birch, R.14
Anand, P.15
Buell, G.N.16
-
46
-
-
74949123761
-
P2X7-dependent release of interleukin-1beta and nociception in the spinal cord following lipopolysaccharide
-
Clark A, Staniland A, Marchand F, Kaan T, McMahon S, Malcangio M. P2X7-dependent release of interleukin-1beta and nociception in the spinal cord following lipopolysaccharide. J Neurosci. 2010;30:573-82.
-
(2010)
J Neurosci
, vol.30
, pp. 573-582
-
-
Clark, A.1
Staniland, A.2
Marchand, F.3
Kaan, T.4
McMahon, S.5
Malcangio, M.6
-
47
-
-
67449087580
-
P2X7 deficiency attenuates renal injury in experimental glomerulonephritis
-
Taylor S, Turner C, Elliott J, McDaid J, Hewitt R, Smith J, PickeringM,WhitehouseD,CookH,BurnstockG, PuseyC,Unwin R, Tam F. P2X7 deficiency attenuates renal injury in experimental glomerulonephritis. J Am Soc Nephrol. 2009;20:1275-81.
-
(2009)
J Am Soc Nephrol
, vol.20
, pp. 1275-1281
-
-
Taylor, S.1
Turner, C.2
Elliott, J.3
McDaid, J.4
Hewitt, R.5
Smith, J.6
Pickering, M.7
Whitehouse, D.8
Cook, H.9
Burnstock, G.10
Pusey, C.11
Unwin, R.12
Tam, F.13
-
48
-
-
48049084135
-
The cytokine hypothesis of depression: Inflammation, oxidative & nitrosative stress (IO&NS) and leaky gut as new targets for adjunctive treatments in depression
-
Maes M. The cytokine hypothesis of depression: inflammation, oxidative & nitrosative stress (IO&NS) and leaky gut as new targets for adjunctive treatments in depression. Neuro Endocrinol Lett. 2008;29:287-91.
-
(2008)
Neuro Endocrinol Lett
, vol.29
, pp. 287-291
-
-
Maes, M.1
-
49
-
-
0025910497
-
The macrophage theory of depression
-
Smith RS. The macrophage theory of depression. Med Hypotheses. 1991;35:298-306.
-
(1991)
Med Hypotheses
, vol.35
, pp. 298-306
-
-
Smith, R.S.1
-
50
-
-
14744291432
-
Cytokines as a precipitant of depressive illness: Animal and human studies
-
DOI 10.2174/1381612053381701
-
Anisman H, Merali Z, Poulter MO, Hayley S. Cytokines as a precipitant of depressive illness: animal and human studies. Curr Pharm Des. 2005;11:963-72. (Pubitemid 40331298)
-
(2005)
Current Pharmaceutical Design
, vol.11
, Issue.8
, pp. 963-972
-
-
Anisman, H.1
Merali, Z.2
Poulter, M.O.3
Hayley, S.4
-
51
-
-
0036904039
-
Cytokine-induced changes in mood and behaviour: Implications for 'depression due to a general medical condition', immunotherapy and antidepressive treatment
-
Pollak Y, Yirmiya R. Cytokine-induced changes in mood and behaviour: implications for 'depression due to a general medical condition', immunotherapy and antidepressive treatment. Int J Neuropsychopharmacol. 2002;5:389-99.
-
(2002)
Int J Neuropsychopharmacol
, vol.5
, pp. 389-399
-
-
Pollak, Y.1
Yirmiya, R.2
-
52
-
-
58549092549
-
Behavioral profile of P2X7 receptor knockout mice in animal models of depression and anxiety: Relevance for neuropsychiatric disorders
-
Basso A, Bratcher N, Harris R, Jarvis M, Decker M, Rueter L. Behavioral profile of P2X7 receptor knockout mice in animal models of depression and anxiety: relevance for neuropsychiatric disorders. Behav Brain Res. 2009;198:83-90.
-
(2009)
Behav Brain Res
, vol.198
, pp. 83-90
-
-
Basso, A.1
Bratcher, N.2
Harris, R.3
Jarvis, M.4
Decker, M.5
Rueter, L.6
-
53
-
-
77956578083
-
Association of P2X7 receptor +1513 (A->C) polymorphism with tuberculosis in a Punjabi population
-
Sharma S, Kumar V, Khosla R, Kajal N, Sarin B, Sehajpal P. Association of P2X7 receptor +1513 (A->C) polymorphism with tuberculosis in a Punjabi population. Int J Tuberc Lung Dis. 2010;14:1159-63.
-
(2010)
Int J Tuberc Lung Dis
, vol.14
, pp. 1159-1163
-
-
Sharma, S.1
Kumar, V.2
Khosla, R.3
Kajal, N.4
Sarin, B.5
Sehajpal, P.6
-
54
-
-
78650399138
-
Metaanalysis of P2X7 gene polymorphisms and tuberculosis susceptibility
-
Xiao J, Sun L, Yan H, Jiao W, Miao Q, Feng W, Wu X, Gu Y, Jiao A, Guo Y, Peng X, Shen A. Metaanalysis of P2X7 gene polymorphisms and tuberculosis susceptibility. FEMS Immunol Med Microbiol. 2010;60:165-70.
-
(2010)
FEMS Immunol Med Microbiol
, vol.60
, pp. 165-170
-
-
Xiao, J.1
Sun, L.2
Yan, H.3
Jiao, W.4
Miao, Q.5
Feng, W.6
Wu, X.7
Gu, Y.8
Jiao, A.9
Guo, Y.10
Peng, X.11
Shen, A.12
-
55
-
-
34247842792
-
7 and NRAMP1/SLC11 A1 gene polymorphisms in Mexican mestizo patients with pulmonary tuberculosis
-
DOI 10.1111/j.1365-2249.2007.03359.x
-
Niño-Moreno P, Portales-Pérez D, Hernández-Castro B, Portales- Cervantes L, Flores-Meraz V, Baranda L, Gómez-Gómez A, Acuña-Alonzo V, Granados J, González-Amaro R. P2X7 and NRAMP1/SLC11 A1 gene polymorphisms in Mexican mestizo patients with pulmonary tuberculosis. Clin Exp Immunol. 2007; 148:469-77. (Pubitemid 46701022)
-
(2007)
Clinical and Experimental Immunology
, vol.148
, Issue.3
, pp. 469-477
-
-
Nino-Moreno, P.1
Portales-Perez, D.2
Hernandez-Castro, B.3
Portales-Cervantes, L.4
Flores-Meraz, V.5
Baranda, L.6
Gomez-Gomez, A.7
Acuna-Alonzo, V.8
Granados, J.9
Gonzalez-Amaro, R.10
-
56
-
-
77955140975
-
Polymorphism in the p2x7 gene increases susceptibility to extrapulmonary tuberculosis in Turkish children
-
Tekin D, Kayaalti Z, Dalgic N, Cakir E, Soylemezoglu T, Isin Kutlubay B, Aydin Kilic B. Polymorphism in the p2x7 gene increases susceptibility to extrapulmonary tuberculosis in Turkish children. Pediatr Infect Dis J. 2010;29:779-82.
-
(2010)
Pediatr Infect Dis J
, vol.29
, pp. 779-782
-
-
Tekin, D.1
Kayaalti, Z.2
Dalgic, N.3
Cakir, E.4
Soylemezoglu, T.5
Isin Kutlubay, B.6
Aydin Kilic, B.7
-
57
-
-
33847052870
-
Polymorphism in the P2X7 gene increases susceptibility to extrapulmonary tuberculosis
-
Fernando S, Saunders B, Sluyter R, Skarratt K, Goldberg H, Marks G, Wiley J, Britton WA. Polymorphism in the P2X7 gene increases susceptibility to extrapulmonary tuberculosis. Am J Respir Crit Care Med. 2007;175:360-6.
-
(2007)
Am J Respir Crit Care Med
, vol.175
, pp. 360-366
-
-
Fernando, S.1
Saunders, B.2
Sluyter, R.3
Skarratt, K.4
Goldberg, H.5
Marks, G.6
Wiley, J.7
Britton, W.A.8
-
58
-
-
0035815630
-
7 Receptor
-
DOI 10.1074/jbc.M010353200
-
Gu B, Zhang W, Worthington R, Sluyter R, Dao-Ung P, Petrou S, Barden J, Wiley JS. A Glu-496 to Ala polymorphism leads to loss of function of the human P2X7 receptor. J Biol Chem. 2001;276: 11135-42. (Pubitemid 38089296)
-
(2001)
Journal of Biological Chemistry
, vol.276
, Issue.14
, pp. 11135-11142
-
-
Gu, B.J.1
Zhang, W.2
Worthington, R.A.3
Sluyter, R.4
Dao-Ung, P.5
Petrou, S.6
Barden, J.A.7
Wiley, J.S.8
-
59
-
-
0037362564
-
Glu496Ala polymorphism of human P2X7 receptor does not affect its electrophysiological phenotype
-
Boldt W, Klapperstück M, Büttner C, Sadtler S, Schmalzing G, Markwardt F. Glu496Ala polymorphism of human P2X7 receptor does not affect its electrophysiological phenotype. Am J Physiol Cell Physiol. 2003;284:C749-56.
-
(2003)
Am J Physiol Cell Physiol
, vol.284
-
-
Boldt, W.1
Klapperstück, M.2
Büttner, C.3
Sadtler, S.4
Schmalzing, G.5
Markwardt, F.6
-
60
-
-
21244471404
-
7 receptor of human leukemic lymphocytes
-
Cabrini G, Falzoni S, Forchap S, Pellegatti P, Balboni A, Agostini P, Cuneo A, Castoldi G, Baricordi O, Di Virgilio FA. His-155 to Tyr polymorphism confers gain-of-function to the human P2X7 receptor of human leukemic lymphocytes. J Immunol. 2005;175:82-9. (Pubitemid 40884304)
-
(2005)
Journal of Immunology
, vol.175
, Issue.1
, pp. 82-89
-
-
Cabrini, G.1
Falzoni, S.2
Forchap, S.L.3
Pellegatti, P.4
Balboni, A.5
Agostini, P.6
Cuneo, A.7
Castoldi, G.8
Baricordi, O.R.9
Di, V.F.10
-
61
-
-
1542619335
-
7 Receptor Impairs ATP-Induced IL-1beta Release from Human Monocytes
-
Sluyter R, Shemon AN, Wiley JS. Glu496 to Ala polymorphism in the P2X7 receptor impairs ATP-induced IL-1 beta release from human monocytes. J Immunol. 2004;172:3399-405. (Pubitemid 38337918)
-
(2004)
Journal of Immunology
, vol.172
, Issue.6
, pp. 3399-3405
-
-
Sluyter, R.1
Shemon, A.N.2
Wiley, J.S.3
-
62
-
-
33745047597
-
Analysis of single nucleotide polymorphisms in genes in the chromosome 12Q24.31 region points to P2RX7 as a susceptibility gene to bipolar affective disorder
-
Barden N, Harvey M, Gagné B, Shink E, Tremblay M, Raymond C, Labbé M, Villeneuve A, Rochette D, Bordeleau L, Stadler H, Holsboer F, Müller-Myhsok B. Analysis of single nucleotide polymorphisms in genes in the chromosome 12Q24.31 region points to P2RX7 as a susceptibility gene to bipolar affective disorder. Am J Med Genet B Neuropsychiatr Genet. 2006;141B:374-82.
-
(2006)
Am J Med Genet B Neuropsychiatr Genet
, vol.141 B
, pp. 374-382
-
-
Barden, N.1
Harvey, M.2
Gagné, B.3
Shink, E.4
Tremblay, M.5
Raymond, C.6
Labbé, M.7
Villeneuve, A.8
Rochette, D.9
Bordeleau, L.10
Stadler, H.11
Holsboer, F.12
Müller-Myhsok, B.13
-
63
-
-
61449251630
-
Association between depression and the Gln460Arg polymorphism of P2RX7 gene: A dimensional approach
-
Hejjas K, Szekely A, Domotor E, Halmai Z, Balogh G, Schilling B, Sarosi A, Faludi G, Sasvari-Szekely M, Nemoda Z. Association between depression and the Gln460Arg polymorphism of P2RX7 gene: a dimensional approach. Am J Med Genet B Neuropsychiatr Genet. 2009;150B:295-9.
-
(2009)
Am J Med Genet B Neuropsychiatr Genet
, vol.150 B
, pp. 295-299
-
-
Hejjas, K.1
Szekely, A.2
Domotor, E.3
Halmai, Z.4
Balogh, G.5
Schilling, B.6
Sarosi, A.7
Faludi, G.8
Sasvari-Szekely, M.9
Nemoda, Z.10
-
64
-
-
70349311857
-
Variation in P2RX7 candidate gene (rs2230912) is not associated with bipolar I disorder and unipolar major depression in four European samples
-
Grigoroiu-Serbanescu M, Herms S, Mühleisen T, Georgi A, Diaconu C, Strohmaier J, Czerski P, Hauser J, Leszczynska- Rodziewicz A, Jamra R, Babadjanova G, Tiganov A, Krasnov V, Kapiletti S, Neagu A, Vollmer J, Breuer R, Rietschel M, Nöthen M, Cichon S, Propping P. Variation in P2RX7 candidate gene (rs2230912) is not associated with bipolar I disorder and unipolar major depression in four European samples. Am J Med Genet B Neuropsychiatr Genet. 2009;150B:1017-21.
-
(2009)
Am J Med Genet B Neuropsychiatr Genet
, vol.150 B
, pp. 1017-1021
-
-
Grigoroiu-Serbanescu, M.1
Herms, S.2
Mühleisen, T.3
Georgi, A.4
Diaconu, C.5
Strohmaier, J.6
Czerski, P.7
Hauser, J.8
Leszczynska-Rodziewicz, A.9
Jamra, R.10
Babadjanova, G.11
Tiganov, A.12
Krasnov, V.13
Kapiletti, S.14
Neagu, A.15
Vollmer, J.16
Breuer, R.17
Rietschel, M.18
Nöthen, M.19
Cichon, S.20
Propping, P.21
more..
-
65
-
-
66249146391
-
Case-control studies show that a non-conservative amino-acid change from a glutamine to arginine in the P2RX7 purinergic receptor protein is associated with both bipolar- and unipolar-affective disorders
-
McQuillin A, Bass N, Choudhury K, Puri V, Kosmin M, Lawrence J, Curtis D, Gurling H. Case-control studies show that a non-conservative amino-acid change from a glutamine to arginine in the P2RX7 purinergic receptor protein is associated with both bipolar- and unipolar-affective disorders. Mol Psychiatry. 2009;14:614-20.
-
(2009)
Mol Psychiatry
, vol.14
, pp. 614-620
-
-
McQuillin, A.1
Bass, N.2
Choudhury, K.3
Puri, V.4
Kosmin, M.5
Lawrence, J.6
Curtis, D.7
Gurling, H.8
-
66
-
-
33646924818
-
7 pore function predicts allele linkage disequilibrium
-
DOI 10.1373/clinchem.2005.065425
-
Denlinger LC, Coursin D, Schell K, Angelini G, Green D, Guadarrama AG, Halsey J, Prabhu U, Hogan K, Bertics PJ. Human P2X7 pore function predicts allele linkage disequilibrium. Clin Chem. 2006;52:995-1004. (Pubitemid 43794409)
-
(2006)
Clinical Chemistry
, vol.52
, Issue.6
, pp. 995-1004
-
-
Denlinger, L.C.1
Coursin, D.B.2
Schell, K.3
Angelini, G.4
Green, D.N.5
Guadarrama, A.G.6
Halsey, J.7
Prabhu, U.8
Hogan, K.J.9
Bertics, P.J.10
-
67
-
-
77954887909
-
Evidence for associations between the purinergic receptor P2X(7) (P2RX7) and toxoplasmosis
-
Jamieson SE, Peixoto-Rangel AL, Hargrave AC, Roubaix LA, Mui EJ, Boulter NR, Miller EN, Fuller SJ, Wiley JS, Castellucci L, Boyer K, Peixe RG, Kirisits MJ, LeS Elias, Coyne JJ, Correa- Oliveira R, Sautter M, Smith NC, Lees MP, Swisher CN, Heydemann P, Noble AG, Patel D, Bardo D, Burrowes D, McLone D, Roizen N, Withers S, Bahia-Oliveira LM, McLeod R, Blackwell JM. Evidence for associations between the purinergic receptor P2X(7) (P2RX7) and toxoplasmosis. Genes Immun. 2010;11:374-83.
-
(2010)
Genes Immun
, vol.11
, pp. 374-383
-
-
Jamieson, S.E.1
Peixoto-Rangel, A.L.2
Hargrave, A.C.3
Roubaix, L.A.4
Mui, E.J.5
Boulter, N.R.6
Miller, E.N.7
Fuller, S.J.8
Wiley, J.S.9
Castellucci, L.10
Boyer, K.11
Peixe, R.G.12
Kirisits, M.J.13
Elias, L.14
Coyne, J.J.15
Correa-Oliveira, R.16
Sautter, M.17
Smith, N.C.18
Lees, M.P.19
Swisher, C.N.20
Heydemann, P.21
Noble, A.G.22
Patel, D.23
Bardo, D.24
Burrowes, D.25
McLone, D.26
Roizen, N.27
Withers, S.28
Bahia-Oliveira, L.M.29
McLeod, R.30
Blackwell, J.M.31
more..
-
68
-
-
15444364434
-
7 nucleotide receptor polymorphisms by a novel monocyte pore assay predictive of alterations in lipopolysaccharide- induced cytokine production
-
Denlinger LC, Angelini G, Schell K, Green D, Guadarrama AG, Prabhu U, Coursin D, Bertics PJ, Hogan K. Detection of human P2X7 nucleotide receptor polymorphisms by a novel monocyte pore assay predictive of alterations in lipopolysaccharideinduced cytokine production. J Immunol. 2005;174:4424-31. (Pubitemid 40396026)
-
(2005)
Journal of Immunology
, vol.174
, Issue.7
, pp. 4424-4431
-
-
Denlinger, L.C.1
Angelini, G.2
Schell, K.3
Green, D.N.4
Guadarrama, A.G.5
Prabhu, U.6
Coursin, D.B.7
Bertics, P.J.8
Hogan, K.9
-
69
-
-
60449100436
-
Selective P2X(7) receptor antagonists for chronic inflammation and pain
-
Carroll WA, Donnelly-Roberts D, Jarvis MF. Selective P2X(7) receptor antagonists for chronic inflammation and pain. Purinergic Signal. 2009;5:63-73.
-
(2009)
Purinergic Signal
, vol.5
, pp. 63-73
-
-
Carroll, W.A.1
Donnelly-Roberts, D.2
Jarvis, M.F.3
-
70
-
-
79955597008
-
-
ClinicalTrials.gov Home Page. Accessed 2 Jan, 2011
-
ClinicalTrials.gov Home Page. http://www.clinicaltrials.gov (Accessed 2 Jan, 2011).
-
-
-
-
71
-
-
84871392004
-
-
Accessed 2 Jan , 2011
-
Pfizer Pipeline. http://media.pfizer.com/files/research/pipeline/ 2008-0930/pipeline-2008-0930.pdf (Accessed 2 Jan , 2011).
-
Pfizer Pipeline
-
-
-
73
-
-
79955577771
-
-
accessed January 2, 2011
-
Affectis Pharmaceuticals AG. http://www.affectis.com/attach ments/011-Affectis%20-%20Patent%20Update-02Apr09.pdf (accessed January 2, 2011).
-
Affectis Pharmaceuticals AG
-
-
-
74
-
-
77953475814
-
Mechanical factors and bone health: Effects of weightlessness and neurologic injury
-
Amin S. Mechanical factors and bone health: effects of weightlessness and neurologic injury. Curr Rheumatol Rep. 2010;12: 170-6.
-
(2010)
Curr Rheumatol Rep
, vol.12
, pp. 170-176
-
-
Amin, S.1
-
75
-
-
34250210564
-
Single nucleotide polymorphisms in the P2X7 gene are associated to fracture risk and to effect of estrogen treatment
-
DOI 10.1097/FPC.0b013e3280951625, PII 0121301120070700000010
-
Ohlendorff SD, Tofteng CL, Jensen JE, Petersen S, Civitelli R, Fenger M, Abrahamsen B, Hermann AP, Eiken P, Jørgensen NR, Jrgensen NR. Single nucleotide polymorphisms in the P2X7 gene are associated to fracture risk and to effect of estrogen treatment. Pharmacogenet Genomics. 2007;17:555-67. (Pubitemid 46905222)
-
(2007)
Pharmacogenetics and Genomics
, vol.17
, Issue.7
, pp. 555-567
-
-
Ohlendorff, S.D.1
Tofteng, C.L.2
Jensen, J.-E.B.3
Petersen, S.4
Civitelli, R.5
Fenger, M.6
Abrahamsen, B.7
Hermann, A.P.8
Eiken, P.9
Jrgensen, N.R.10
-
76
-
-
33646072818
-
7 receptor: A key player in IL-1 processing and release
-
Ferrari D, Pizzirani C, Adinolfi E, Lemoli R, Curti A, Idzko M, Panther E, Di Virgilio F. The P2X7 receptor: a key player in IL-1 processing and release. J Immunol. 2006;176:3877-83. (Pubitemid 44264361)
-
(2006)
Journal of Immunology
, vol.176
, Issue.7
, pp. 3877-3883
-
-
Ferrari, D.1
Pizzirani, C.2
Adinolfi, E.3
Lemoli, R.M.4
Curti, A.5
Idzko, M.6
Panther, E.7
Di, V.F.8
-
77
-
-
33644869901
-
Inflammation and neurodegenerative diseases
-
Griffin WS. Inflammation and neurodegenerative diseases. Am J Clin Nutr. 2006;83:470S-4S.
-
(2006)
Am J Clin Nutr
, vol.83
-
-
Griffin, W.S.1
-
78
-
-
34548614009
-
Nonclassical IL-1 beta secretion stimulated by P2X7 receptors is dependent on in- flammasome activation and correlated with exosome release in murine macrophages
-
Qu Y, Franchi L, Nunez G, Dubyak GR. Nonclassical IL-1 beta secretion stimulated by P2X7 receptors is dependent on in- flammasome activation and correlated with exosome release in murine macrophages. J Immunol. 2007;179:1913-25.
-
(2007)
J Immunol
, vol.179
, pp. 1913-1925
-
-
Qu, Y.1
Franchi, L.2
Nunez, G.3
Dubyak, G.R.4
-
79
-
-
34548444551
-
Liaisons dangereuses: P2X(7) and the inflammasome
-
Di Virgilio F. Liaisons dangereuses: P2X(7) and the inflammasome. Trends Pharmacol Sci. 2007;28:465-72.
-
(2007)
Trends Pharmacol Sci
, vol.28
, pp. 465-472
-
-
Di Virgilio, F.1
-
80
-
-
69149106095
-
Modulation of the ATP-lnduced release and processing of IL-1beta in microglial cells
-
Takenouchi T, Sugama S, Iwamaru Y, Hashimoto M, Kitani H. Modulation of the ATP-lnduced release and processing of IL-1beta in microglial cells. Crit Rev Immunol. 2009;29:335-45.
-
(2009)
Crit Rev Immunol
, vol.29
, pp. 335-345
-
-
Takenouchi, T.1
Sugama, S.2
Iwamaru, Y.3
Hashimoto, M.4
Kitani, H.5
-
81
-
-
0037096207
-
7 receptor alters leukocyte function and attenuates an inflammatory response
-
Labasi JM, Petrushova N, Donovan C, McCurdy S, Lira P, Payette MM, Brissette W, Wicks JR, Audoly L, Gabel CA. Absence of the P2X7 receptor alters leukocyte function and attenuates an inflammatory response. J Immunol. 2002;168: 6436-45. (Pubitemid 34620068)
-
(2002)
Journal of Immunology
, vol.168
, Issue.12
, pp. 6436-6445
-
-
Labasi, J.M.1
Petrushova, N.2
Donovan, C.3
McCurdy, S.4
Lira, P.5
Payette, M.M.6
Brissette, W.7
Wicks, J.R.8
Audoly, L.9
Gabel, C.A.10
-
82
-
-
1842581655
-
7 Receptor Activator, the Human Cathelicidin-Derived Peptide LL37, Induces IL-1beta Processing and Release
-
Elssner A, Duncan M, Gavrilin M, Wewers MD. A novel P2X7 receptor activator, the human cathelicidin-derived peptide LL37, induces IL-1 beta processing and release. J Immunol. 2004;172: 4987-94. (Pubitemid 38456425)
-
(2004)
Journal of Immunology
, vol.172
, Issue.8
, pp. 4987-4994
-
-
Elssner, A.1
Duncan, M.2
Gavrilin, M.3
Wewers, M.D.4
-
83
-
-
33750473352
-
7 receptor
-
DOI 10.1038/sj.emboj.7601378, PII 7601378
-
Pelegrin P, Surprenant A. Pannexin-1 mediates large pore formation and interleukin-1beta release by the ATP-gated P2X7 receptor. The EMBO J. 2006;25:5071-82. (Pubitemid 44658525)
-
(2006)
EMBO Journal
, vol.25
, Issue.21
, pp. 5071-5082
-
-
Pelegrin, P.1
Surprenant, A.2
-
84
-
-
47249144272
-
P2X7 receptor differentially couples to distinct release pathways for IL-1beta in mouse macrophage
-
Pelegrin P, Barroso-Gutierrez C, Surprenant A. P2X7 receptor differentially couples to distinct release pathways for IL-1beta in mouse macrophage. J Immunol. 2008;180:7147-57.
-
(2008)
J Immunol
, vol.180
, pp. 7147-7157
-
-
Pelegrin, P.1
Barroso-Gutierrez, C.2
Surprenant, A.3
-
85
-
-
40749157181
-
7 expression after Atp stimulation by peripheral blood mononuclear cells isolated from rheumatoid arthritis patients and normal healthy controls
-
DOI 10.1007/s10753-007-9052-0
-
Al-Shukaili A, Al-Kaabi J, Hassan B. A comparative study of interleukin-1beta production and p2x7 expression after ATP stimulation by peripheral blood mononuclear cells isolated from rheumatoid arthritis patients and normal healthy controls. Inflammation. 2008;31:84-90. (Pubitemid 351388891)
-
(2008)
Inflammation
, vol.31
, Issue.2
, pp. 84-90
-
-
Al-Shukaili, A.1
Al-Kaabi, J.2
Hassan, B.3
-
86
-
-
0031983986
-
Glial-neuronal interactions in Alzheimer's disease: The potential role of a 'cytokine cycle' in disease progression
-
Griffin WS, Sheng JG, Royston MC, Gentleman SM, McKenzie JE, Graham DI, Roberts GW, Mrak RE. Glial-neuronal interactions in Alzheimer's disease: the potential role of a 'cytokine cycle' in disease progression. Brain Pathol. 1998;8:65-72.
-
(1998)
Brain Pathol
, vol.8
, pp. 65-72
-
-
Griffin, W.S.1
Sheng, J.G.2
Royston, M.C.3
Gentleman, S.M.4
McKenzie, J.E.5
Graham, D.I.6
Roberts, G.W.7
Mrak, R.E.8
-
87
-
-
0038143359
-
7 mediates superoxide production in primary microglia and is up-regulated in a transgenic mouse model of Alzheimer's disease
-
DOI 10.1074/jbc.M209478200
-
Parvathenani LK, Tertyshnikova S, Greco CR, Roberts SB, Robertson B, Posmantur R. P2X7 mediates superoxide production in primary microglia and is up-regulated in a transgenic mouse model of Alzheimer's disease. J Biol Chem. 2003;278: 13309-17. (Pubitemid 36800102)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.15
, pp. 13309-13317
-
-
Parvathenani, L.K.1
Tertyshnikova, S.2
Greco, C.R.3
Roberts, S.B.4
Robertson, B.5
Posmantur, R.6
-
88
-
-
45249094554
-
7 receptor-mediated IL-1beta release
-
DOI 10.1111/j.1471-4159.2008.05387.x
-
Bernardino L, Balosso S, Ravizza T, Marchi N, Ku G, Randle JC, Malva JO, Vezzani A. Inflammatory events in hippocampal slice cultures prime neuronal susceptibility to excitotoxic injury: a crucial role of P2X7 receptor-mediated IL-1beta release. J Neurochem. 2008;106:271-80. (Pubitemid 351840213)
-
(2008)
Journal of Neurochemistry
, vol.106
, Issue.1
, pp. 271-280
-
-
Bernardino, L.1
Balosso, S.2
Ravizza, T.3
Marchi, N.4
Ku, G.5
Randle, J.C.6
Malva, J.O.7
Vezzani, A.8
-
90
-
-
34247110322
-
Nucleotide receptor signaling in murine macrophages is linked to reactive oxygen species generation
-
DOI 10.1016/j.freeradbiomed.2007.02.010, PII S0891584907001153
-
Pfeiffer ZA, Guerra AN, Hill LM, Gavala ML, Prabhu U, Aga M, Hall DJ, Bertics PJ. Nucleotide receptor signaling in murine macrophages is linked to reactive oxygen species generation. Free Radical Biol & Med. 2007;42:1506-16. (Pubitemid 46590610)
-
(2007)
Free Radical Biology and Medicine
, vol.42
, Issue.10
, pp. 1506-1516
-
-
Pfeiffer, Z.A.1
Guerra, A.N.2
Hill, L.M.3
Gavala, M.L.4
Prabhu, U.5
Aga, M.6
Hall, D.J.7
Bertics, P.J.8
-
91
-
-
37449011204
-
In vitro and in vivo evidence for a role of the P2X7 receptor in the release of IL-1 beta in the murine brain
-
Mingam R, De Smedt V, Amédée T, Bluthé RM, Kelley KW, Dantzer R, Layé S. In vitro and in vivo evidence for a role of the P2X7 receptor in the release of IL-1 beta in the murine brain. Brain Behav Immun. 2008;22:234-44.
-
(2008)
Brain Behav Immun
, vol.22
, pp. 234-244
-
-
Mingam, R.1
De Smedt, V.2
Amédée, T.3
Bluthé, R.M.4
Kelley, K.W.5
Dantzer, R.6
Layé, S.7
-
92
-
-
27444433860
-
7 receptor activation in rat brain cultured astrocytes increases the biosynthetic release of cysteinyl leukotrienes
-
Ballerini P, Ciccarelli R, Caciagli F, Rathbone MP, Werstiuk ES, Traversa U, Buccella S, Giuliani P, Jang S, Nargi E, Visini D, Santavenere C, Di Iorio P. P2X7 receptor activation in rat brain cultured astrocytes increases the biosynthetic release of cysteinyl leukotrienes. Int J Immunopathol Pharmacol. 2005;18: 417-30. (Pubitemid 41532358)
-
(2005)
International Journal of Immunopathology and Pharmacology
, vol.18
, Issue.3
, pp. 417-430
-
-
Ballerini, P.1
Ciccarelli, R.2
Caciagli, F.3
Rathbone, M.P.4
Werstiuk, E.S.5
Traversa, U.6
Buccella, S.7
Giuliani, P.8
Jiang, S.9
Nargi, E.10
Visini, D.11
Santavenere, C.12
Di, I.P.13
-
93
-
-
67349232457
-
Different properties of P2X(7) receptor in hippocampal and cortical astrocytes
-
Bianco F, Colombo A, Saglietti L, Lecca D, Abbracchio MP, Matteoli M, Verderio C. Different properties of P2X(7) receptor in hippocampal and cortical astrocytes. Purinergic Signal. 2009;5:233-40.
-
(2009)
Purinergic Signal
, vol.5
, pp. 233-240
-
-
Bianco, F.1
Colombo, A.2
Saglietti, L.3
Lecca, D.4
Abbracchio, M.P.5
Matteoli, M.6
Verderio, C.7
-
94
-
-
0027298505
-
Cytokine production by human fetal microglia and astrocytes: Differential induction by lipopolysaccharide and IL-1beta
-
Lee SC, Liu W, Dickson DW, Brosnan CF, Berman JW. Cytokine production by human fetal microglia and astrocytes. Differential induction by lipopolysaccharide and IL-1 beta. J Immunol. 1993;150:2659-67. (Pubitemid 23127515)
-
(1993)
Journal of Immunology
, vol.150
, Issue.7
, pp. 2659-2667
-
-
Lee, S.C.1
Liu, W.2
Dickson, D.W.3
Brosnan, C.F.4
Berman, J.W.5
-
95
-
-
13244299100
-
7 receptor expression and function in human astrocytes
-
DOI 10.1002/glia.20110
-
Narcisse L, Scemes E, Zhao Y, Lee SC, Brosnan CF. The cytokine IL-1beta transiently enhances P2X7 receptor expression and function in human astrocytes. Glia. 2005;49:245-58. (Pubitemid 40188503)
-
(2005)
GLIA
, vol.49
, Issue.2
, pp. 245-258
-
-
Narcisse, L.1
Scemes, E.2
Zhao, Y.3
Lee, S.C.4
Brosnan, C.F.5
-
96
-
-
0036200917
-
Purinergic (P2X7) receptor activation of microglia induces cell death via an interleukin-1-independent mechanism
-
DOI 10.1006/mcne.2001.1054
-
Brough D, Le Feuvre RA, Iwakura Y, Rothwell NJ. Purinergic (P2X7) receptor activation of microglia induces cell death via an interleukin-1- independent mechanism. Mol Cell Neurosci. 2002; 19:272-80. (Pubitemid 34211906)
-
(2002)
Molecular and Cellular Neuroscience
, vol.19
, Issue.2
, pp. 272-280
-
-
Brough, D.1
Le, F.R.A.2
Iwakura, Y.3
Rothwell, N.J.4
-
98
-
-
0032538560
-
Purinergic receptor modulation of lipopolysaccharide signaling and inducible nitric-oxide synthase expression in RAW 264.7 Macrophages
-
DOI 10.1074/jbc.273.42.27170
-
Hu Y, Fisette PL, Denlinger LC, Guadarrama AG, Sommer JA, Proctor RA, Bertics PJ. Purinergic receptor modulation of lipopolysaccharide signaling and inducible nitric-oxide synthase expression in RAW 264.7 macrophages. J Biol Chem. 1998;273: 27170-5. (Pubitemid 28500425)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.42
, pp. 27170-27175
-
-
Hu, Y.1
Fisette, P.L.2
Denlinger, L.C.3
Guadarrama, A.G.4
Sommer, J.A.5
Proctor, R.A.6
Bertics, P.J.7
-
99
-
-
38149036646
-
Expression and function of the P2X(7) receptor in rat C6 glioma cells
-
Wei W, Ryu J, Choi H, McLarnon J. Expression and function of the P2X(7) receptor in rat C6 glioma cells. Cancer Lett. 2008;260:79-87.
-
(2008)
Cancer Lett
, vol.260
, pp. 79-87
-
-
Wei, W.1
Ryu, J.2
Choi, H.3
McLarnon, J.4
-
100
-
-
67649365966
-
Autocrine regulation of T-cell activation by ATP release and P2X7 receptors
-
Yip L, Woehrle T, Corriden R, Hirsh M, Chen Y, Inoue Y, Ferrari V, Insel PA, Junger WG. Autocrine regulation of T-cell activation by ATP release and P2X7 receptors. FASEB J. 2009; 23:1685-93.
-
(2009)
FASEB J
, vol.23
, pp. 1685-1693
-
-
Yip, L.1
Woehrle, T.2
Corriden, R.3
Hirsh, M.4
Chen, Y.5
Inoue, Y.6
Ferrari, V.7
Insel, P.A.8
Junger, W.G.9
-
101
-
-
57249111810
-
Activation of P2X7 receptors induces CCL3 production in microglial cells through transcription factor NFAT
-
Kataoka A, Tozaki-Saitoh H, Koga Y, Tsuda M, Inoue K. Activation of P2X7 receptors induces CCL3 production in microglial cells through transcription factor NFAT. J Neurochem. 2009;108:115-25.
-
(2009)
J Neurochem
, vol.108
, pp. 115-125
-
-
Kataoka, A.1
Tozaki-Saitoh, H.2
Koga, Y.3
Tsuda, M.4
Inoue, K.5
-
102
-
-
2142658762
-
Evidence for nucleotide receptor modulation of cross talk between MAP kinase and NF-kappa B signaling pathways in murine RAW 264.7 macrophages
-
Aga M, Watters JJ, Pfeiffer ZA, Wiepz GJ, Sommer JA, Bertics PJ. Evidence for nucleotide receptor modulation of cross talk between MAP kinase and NF-kappa B signaling pathways in murine RAW 264.7 macrophages. Am J Physiol Cell Physiol. 2004;286:C923-30.
-
(2004)
Am J Physiol Cell Physiol
, vol.286
-
-
Aga, M.1
Watters, J.J.2
Pfeiffer, Z.A.3
Wiepz, G.J.4
Sommer, J.A.5
Bertics, P.J.6
-
103
-
-
78349284376
-
The P2X7-Egr pathway regulates nucleotide-dependent inflammatory gene expression in microglia
-
Friedle S, Brautigam V, Nikodemova M, Wright M, Watters JJ. The P2X7-Egr pathway regulates nucleotide-dependent inflammatory gene expression in microglia. Glia. 2011;59:1-13.
-
(2011)
Glia
, vol.59
, pp. 1-13
-
-
Friedle, S.1
Brautigam, V.2
Nikodemova, M.3
Wright, M.4
Watters, J.J.5
-
104
-
-
34548488209
-
P2X(7) receptor stimulation upregulates Egr-1 biosynthesis involving a cytosolic Ca(2+) rise, transactivation of the EGF receptor and phosphorylation of ERK and Elk-1
-
Stefano L, Rössler OG, Griesemer D, Hoth M, Thiel G. P2X(7) receptor stimulation upregulates Egr-1 biosynthesis involving a cytosolic Ca(2+) rise, transactivation of the EGF receptor and phosphorylation of ERK and Elk-1. J Cell Physiol. 2007;213:36-44.
-
(2007)
J Cell Physiol
, vol.213
, pp. 36-44
-
-
Stefano, L.1
Rössler, O.G.2
Griesemer, D.3
Hoth, M.4
Thiel, G.5
-
106
-
-
47949097072
-
Vascular endothelial growth factor receptor 2 mediates macrophage infiltration into orthotopic pancreatic tumors in mice
-
Dineen SP, Lynn KD, Holloway SE, Miller AF, Sullivan JP, Shames DS, Beck AW, Barnett CC, Fleming JB, Brekken RA. Vascular endothelial growth factor receptor 2 mediates macrophage infiltration into orthotopic pancreatic tumors in mice. Cancer Res. 2008;68:4340-6.
-
(2008)
Cancer Res
, vol.68
, pp. 4340-4346
-
-
Dineen, S.P.1
Lynn, K.D.2
Holloway, S.E.3
Miller, A.F.4
Sullivan, J.P.5
Shames, D.S.6
Beck, A.W.7
Barnett, C.C.8
Fleming, J.B.9
Brekken, R.A.10
-
107
-
-
77957286840
-
Fluid flow-induced soluble vascular endothelial growth factor isoforms regulate actin adaptation in osteoblasts
-
Thi MM, Suadicani SO, Spray DC. Fluid flow-induced soluble vascular endothelial growth factor isoforms regulate actin adaptation in osteoblasts. J Biol Chem. 2010;285:30931-41.
-
(2010)
J Biol Chem
, vol.285
, pp. 30931-30941
-
-
Thi, M.M.1
Suadicani, S.O.2
Spray, D.C.3
-
108
-
-
38449112889
-
The role of chemokines in neutrophil biology
-
DOI 10.2741/2853
-
Kobayashi Y. The role of chemokines in neutrophil biology. Front Biosci. 2008;13:2400-7. (Pubitemid 351599693)
-
(2008)
Frontiers in Bioscience
, vol.13
, Issue.7
, pp. 2400-2407
-
-
Kobayashi, Y.1
-
109
-
-
0038415901
-
Stimulation of P2 purinergic receptors induces the release of eosinophil cationic protein and interleukin-8 from human eosinophils
-
DOI 10.1038/sj.bjp.0705145
-
Idzko M, Panther E, Bremer HC, Sorichter S, Luttmann W, Virchow CJ, Di Virgilio F, Herouy Y, Norgauer J, Ferrari D. Stimulation of P2 purinergic receptors induces the release of eosinophil cationic protein and interleukin-8 from human eosinophils. Br J Pharmacol. 2003;138:1244-50. (Pubitemid 36543121)
-
(2003)
British Journal of Pharmacology
, vol.138
, Issue.7
, pp. 1244-1250
-
-
Idzko, M.1
Panther, E.2
Bremer, H.C.3
Sorichter, S.4
Luttmann, W.5
Virchow Jr., C.J.6
Di, V.F.7
Herouy, Y.8
Norgauer, J.9
Ferrari, D.10
-
110
-
-
34247554240
-
Role of ATP in trauma-associated cytokine release and apoptosis by P2X7 ion channel stimulation
-
DOI 10.1196/annals.1378.027, Signal Transduction Pathways, Part A: Apoptotic and Extracellular Signalling
-
Schneider EM, Vorlaender K, Ma X, Du W, Weiss M. Role of ATP in trauma-associated cytokine release and apoptosis by P2X7 ion channel stimulation. Ann N Y Acad Sci. 2006;1090:245-52. (Pubitemid 47092129)
-
(2006)
Annals of the New York Academy of Sciences
, vol.1090
, pp. 245-252
-
-
Schneider, E.M.1
Vorlaender, K.2
Ma, X.3
Du, W.4
Weiss, M.5
-
111
-
-
77957943307
-
Intravascular danger signals guide neutrophils to sites of sterile inflammation
-
McDonald B, Pittman K, Menezes GB, Hirota SA, Slaba I, Waterhouse CC, Beck PL, Muruve DA, Kubes P. Intravascular danger signals guide neutrophils to sites of sterile inflammation. Science. 2010;330:362-6.
-
(2010)
Science
, vol.330
, pp. 362-366
-
-
McDonald, B.1
Pittman, K.2
Menezes, G.B.3
Hirota, S.A.4
Slaba, I.5
Waterhouse, C.C.6
Beck, P.L.7
Muruve, D.A.8
Kubes, P.9
-
112
-
-
77955890953
-
Interleukin-2 receptor signaling: At the interface between tolerance and immunity
-
Malek TR, Castro I. Interleukin-2 receptor signaling: at the interface between tolerance and immunity. Immunity. 2010;33:153-65.
-
(2010)
Immunity
, vol.33
, pp. 153-165
-
-
Malek, T.R.1
Castro, I.2
-
113
-
-
84984934487
-
Swinging the vote for rapamycin
-
Novak K. Swinging the vote for rapamycin. Nat Rev Cancer. 2002;2:75.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 75
-
-
Novak, K.1
-
115
-
-
77957767675
-
Targeted therapy in melanoma
-
Tawbi H, Nimmagadda N. Targeted therapy in melanoma. Biologics. 2009;3:475-84.
-
(2009)
Biologics
, vol.3
, pp. 475-484
-
-
Tawbi, H.1
Nimmagadda, N.2
-
116
-
-
0037449706
-
lck MAP kinases, and transcription factors AP-1 and NF-kappaB
-
DOI 10.1074/jbc.M206383200
-
Budagian V, Bulanova E, Brovko L, Orinska Z, Fayad R, Paus R, Bulfone-Paus S. Signaling through P2X7 receptor in human T cells involves p56lck, MAP kinases, and transcription factors AP-1 and NF-kappa B. J Biol Chem. 2003;278:1549-60. (Pubitemid 36801383)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.3
, pp. 1549-1560
-
-
Budagian, V.1
Bulanova, E.2
Brovko, L.3
Orinska, Z.4
Fayad, R.5
Paus, R.6
Bulfone-Paus, S.7
-
117
-
-
78649754720
-
Hypertonic stress regulates T cell function via pannexin-1 hemichannels and P2X receptors
-
Woehrle T, Yip L, Manohar M, Sumi Y, Yao Y, Chen Y, Junger WG. Hypertonic stress regulates T cell function via pannexin-1 hemichannels and P2X receptors. J Leukoc Biol. 2010;88:1181-9.
-
(2010)
J Leukoc Biol
, vol.88
, pp. 1181-1189
-
-
Woehrle, T.1
Yip, L.2
Manohar, M.3
Sumi, Y.4
Yao, Y.5
Chen, Y.6
Junger, W.G.7
-
119
-
-
0141884377
-
7 nucleotide receptor activation enhances IFNgamma-induced type II nitric oxide synthase activity in BV-2 microglial cells
-
DOI 10.1046/j.1471-4159.2003.01995.x
-
Gendron FP, Chalimoniuk M, Strosznajder J, Shen S, González FA, Weisman GA, Sun GY. P2X7 nucleotide receptor activation enhances IFN gamma-induced type II nitric oxide synthase activity in BV-2 microglial cells. J Neurochem. 2003;87:344-52. (Pubitemid 37255242)
-
(2003)
Journal of Neurochemistry
, vol.87
, Issue.2
, pp. 344-352
-
-
Gendron, F.-P.1
Chalimoniuk, M.2
Strosznajder, J.3
Shen, S.4
Gonzalez, F.A.5
Weisman, G.A.6
Sun, G.Y.7
-
120
-
-
0033957426
-
ATP-induced killing of virulent Mycobacterium tuberculosis within human macrophages requires phospholipase D
-
Kusner D, Adams J. ATP-induced killing of virulent Mycobacterium tuberculosis within human macrophages requires phospholipase D. J Immunol. 2000;164:379-88. (Pubitemid 30013012)
-
(2000)
Journal of Immunology
, vol.164
, Issue.1
, pp. 379-388
-
-
Kusner, D.J.1
Adams, J.2
-
121
-
-
30044432923
-
Fishing for prostanoids: Deciphering the developmental functions of cyclooxygenase-derived prostaglandins
-
DOI 10.1016/j.ydbio.2005.10.013, PII S0012160605007219
-
Cha Y, Solnica-Krezel L, DuBois R. Fishing for prostanoids: deciphering the developmental functions of cyclooxygenase-derived prostaglandins. Dev Biol. 2006;289:263-72. (Pubitemid 43049931)
-
(2006)
Developmental Biology
, vol.289
, Issue.2
, pp. 263-272
-
-
Cha, Y.I.1
Solnica-Krezel, L.2
DuBois, R.N.3
-
123
-
-
44649092795
-
P2X7 receptors on osteoblasts couple to production of lysophosphatidic acid: A signaling axis promoting osteogenesis
-
DOI 10.1083/jcb.200708037
-
Panupinthu N, Rogers JT, Zhao L, Solano-Flores LP, Possmayer F, Sims SM, Dixon SJ. P2X7 receptors on osteoblasts couple to production of lysophosphatidic acid: a signaling axis promoting osteogenesis. J Cell Biol. 2008;181:859-71. (Pubitemid 351786989)
-
(2008)
Journal of Cell Biology
, vol.181
, Issue.5
, pp. 859-871
-
-
Panupinthu, N.1
Rogers, J.T.2
Zhao, L.3
Solano-Flores, L.P.4
Possmayer, F.5
Sims, S.M.6
Dixon, S.J.7
-
124
-
-
33947583822
-
Osteoimmunology: Shared mechanisms and crosstalk between the immune and bone systems
-
DOI 10.1038/nri2062, PII NRI2062
-
Takayanagi H. Osteoimmunology : shared mechanisms and crosstalk between the immune and bone systems. Nat Rev Immunol. 2007;7:292-304. (Pubitemid 46480961)
-
(2007)
Nature Reviews Immunology
, vol.7
, Issue.4
, pp. 292-304
-
-
Takayanagi, H.1
-
125
-
-
0036732019
-
The role of prostaglandin E2 receptors in the pathogenesis of rheumatoid arthritis
-
DOI 10.1172/JCI200215528
-
McCoy JM, Wicks JR, Audoly LP. The role of prostaglandin E2 receptors in the pathogenesis of rheumatoid arthritis. J Clin Invest. 2002;110:651-8. (Pubitemid 34988789)
-
(2002)
Journal of Clinical Investigation
, vol.110
, Issue.5
, pp. 651-658
-
-
McCoy, J.M.1
Wicks, J.R.2
Audoly, L.P.3
-
126
-
-
77949917259
-
Early growth response transcription factors and the modulation of immune response: Implications towards autoimmunity
-
Gómez-Martín D, Díaz-Zamudio M, Galindo-Campos M, Alcocer-Varela J. Early growth response transcription factors and the modulation of immune response: implications towards autoimmunity. Autoimmun Rev. 2010;9:454-8.
-
(2010)
Autoimmun Rev
, vol.9
, pp. 454-458
-
-
Gómez-Martín, D.1
Díaz-Zamudio, M.2
Galindo-Campos, M.3
Alcocer-Varela, J.4
-
127
-
-
77954594145
-
Early growth response-1 induces and enhances vascular endothelial growth factor-A expression in lung cancer cells
-
Shimoyamada H, Yazawa T, Sato H, Okudela K, Ishii J, Sakaeda M, Kashiwagi K, Suzuki T, Mitsui H, Woo T, Tajiri M, Ohmori T, Ogura T, Masuda M, Oshiro H, Kitamura H. Early growth response-1 induces and enhances vascular endothelial growth factor-A expression in lung cancer cells. Am J Pathol. 2010;177:70-83.
-
(2010)
Am J Pathol
, vol.177
, pp. 70-83
-
-
Shimoyamada, H.1
Yazawa, T.2
Sato, H.3
Okudela, K.4
Ishii, J.5
Sakaeda, M.6
Kashiwagi, K.7
Suzuki, T.8
Mitsui, H.9
Woo, T.10
Tajiri, M.11
Ohmori, T.12
Ogura, T.13
Masuda, M.14
Oshiro, H.15
Kitamura, H.16
-
128
-
-
70350514636
-
NFAT proteins: Emerging roles in cancer progression
-
Mancini M, Toker A. NFAT proteins: emerging roles in cancer progression. Nat Rev Cancer. 2009;9:810-20.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 810-820
-
-
Mancini, M.1
Toker, A.2
-
129
-
-
34447096652
-
2+ entry and NFAT activation in lymphocytes
-
DOI 10.1016/j.ceca.2007.03.007, PII S0143416007000796
-
Gwack Y, Feske S, Srikanth S, Hogan PG, Rao A. Signalling to transcription: store-operated Ca2+ entry and NFAT activation in lymphocytes. Cell Calcium. 2007;42:145-56. (Pubitemid 47029605)
-
(2007)
Cell Calcium
, vol.42
, Issue.2
, pp. 145-156
-
-
Gwack, Y.1
Feske, S.2
Srikanth, S.3
Hogan, P.G.4
Rao, A.5
-
130
-
-
65649141604
-
Expression of the P2X7 receptor increases the Ca2+ content of the endoplasmic reticulum, activates NFATc1, and protects from apoptosis
-
Adinolfi E, Callegari MG, Cirillo M, Pinton P, Giorgi C, Cavagna D, Rizzuto R, Di Virgilio F. Expression of the P2X7 receptor increases the Ca2+ content of the endoplasmic reticulum, activates NFATc1, and protects from apoptosis. J Biol Chem. 2009;284:10120-8.
-
(2009)
J Biol Chem
, vol.284
, pp. 10120-10128
-
-
Adinolfi, E.1
Callegari, M.G.2
Cirillo, M.3
Pinton, P.4
Giorgi, C.5
Cavagna, D.6
Rizzuto, R.7
Di Virgilio, F.8
-
131
-
-
0033531791
-
P2X7/P2Z purinoreceptor-mediated activation of transcription factor NFAT in microglial cells
-
Ferrari D, Stroh C, Schulze-Osthoff K. P2X7/P2Z purinoreceptor-mediated activation of transcription factor NFAT in microglial cells. J Biol Chem. 1999;274:13205-10.
-
(1999)
J Biol Chem
, vol.274
, pp. 13205-13210
-
-
Ferrari, D.1
Stroh, C.2
Schulze-Osthoff, K.3
-
132
-
-
70350764831
-
NF-kappaB signaling pathway, inflammation and colorectal cancer
-
Wang S, Liu Z, Wang L, Zhang X. NF-kappaB signaling pathway, inflammation and colorectal cancer. Cell Mol Immunol. 2009;6:327-34.
-
(2009)
Cell Mol Immunol
, vol.6
, pp. 327-334
-
-
Wang, S.1
Liu, Z.2
Wang, L.3
Zhang, X.4
-
133
-
-
77954520406
-
NFkappaB a promising target for natural products in cancer chemoprevention
-
Luqman S, Pezzuto JM. NFkappaB a promising target for natural products in cancer chemoprevention. Phytother Res. 2010;24:949-63.
-
(2010)
Phytother Res
, vol.24
, pp. 949-963
-
-
Luqman, S.1
Pezzuto, J.M.2
-
134
-
-
0031425953
-
Extracellular ATP activates transcription factor NF-kappaB through the P2Z purinoreceptor by selectively targeting NF-kappaB p65 (RelA)
-
DOI 10.1083/jcb.139.7.1635
-
Ferrari D, Wesselborg S, Bauer MK, Schulze-Osthoff K. Extracellular ATP activates transcription factor NF-kappaB through the P2Z purinoreceptor by selectively targeting NF-kappaB p65. J Cell Biol. 1997;139:1635-43. (Pubitemid 28079229)
-
(1997)
Journal of Cell Biology
, vol.139
, Issue.7
, pp. 1635-1643
-
-
Ferrari, D.1
Wesselborg, S.2
Bauer, M.K.A.3
Schulze-Osthoff, K.4
-
135
-
-
3242673859
-
Extracellular nucleotides act through P2X7 receptors to activate NF-kappaB in osteoclasts
-
DOI 10.1359/JBMR.040108
-
Korcok J, Raimundo LN, Ke HZ, Sims SM, Dixon SJ. Extracellular nucleotides act through P2X7 receptors to activate NF-kappaB in osteoclasts. J Bone Miner Res. 2004;19:642-51. (Pubitemid 41071225)
-
(2004)
Journal of Bone and Mineral Research
, vol.19
, Issue.4
, pp. 642-651
-
-
Korcok, J.1
Raimundo, L.N.2
Ke, H.Z.3
Sims, S.M.4
Dixon, S.J.5
-
136
-
-
78650666211
-
The role of the transcription factor CREB in immune function
-
Wen AY, Sakamoto KM, Miller LS. The role of the transcription factor CREB in immune function. J Immunol. 2010;185:6413-9.
-
(2010)
J Immunol
, vol.185
, pp. 6413-6419
-
-
Wen, A.Y.1
Sakamoto, K.M.2
Miller, L.S.3
-
137
-
-
33745001458
-
Purinergic receptors modulate MAP kinases and transcription factors that control microglial inflammatory gene expression
-
DOI 10.1016/j.neuint.2006.04.005, PII S0197018606001719, Molecular Mechanisms of Neuroinflammation
-
Potucek YD, Crain JM, Watters JJ. Purinergic receptors modulate MAP kinases and transcription factors that control microglial inflammatory gene expression. Neurochem Int. 2006;49:204-14. (Pubitemid 43867079)
-
(2006)
Neurochemistry International
, vol.49
, Issue.2
, pp. 204-214
-
-
Potucek, Y.D.1
Crain, J.M.2
Watters, J.J.3
-
138
-
-
27544468372
-
The Fos family of transcription factors and their role in tumourigenesis
-
DOI 10.1016/j.ejca.2005.08.008, PII S0959804905007082, Transcription Factors in Cancer
-
Milde-Langosch K. The Fos family of transcription factors and their role in tumourigenesis. Eur J Cancer. 2005;41:2449-61. (Pubitemid 41540622)
-
(2005)
European Journal of Cancer
, vol.41
, Issue.16
, pp. 2449-2461
-
-
Milde-Langosch, K.1
-
139
-
-
0025972314
-
ATP-induced activation of human B lymphocytes via P2-purinoceptors
-
Padeh S, Cohen A, Roifman CM. ATP-induced activation of human B lymphocytes via P2-purinoceptors. J Immunol. 1991; 146:1626-32.
-
(1991)
J Immunol
, vol.146
, pp. 1626-1632
-
-
Padeh, S.1
Cohen, A.2
Roifman, C.M.3
-
141
-
-
0026016404
-
A naturally occurring truncated form of FosB that inhibits Fos/Jun transcriptional activity
-
Nakabeppu Y, Nathans D. A naturally occurring truncated form of FosB that inhibits Fos/Jun transcriptional activity. Cell. 1991;64:751-9. (Pubitemid 121001162)
-
(1991)
Cell
, vol.64
, Issue.4
, pp. 751-759
-
-
Nakabeppu, Y.1
Nathans, D.2
-
142
-
-
34250009037
-
Proteasome-dependent and -independent mechanisms for FosB destabilization: Identification of FosB degron domains and implications for DeltaFosB stability
-
DOI 10.1111/j.1460-9568.2007.05575.x
-
Carle T, Ohnishi Y, Ohnishi Y, Alibhai I, Wilkinson M, Kumar A, Nestler E. Proteasome-dependent and -independent mechanisms for FosB destabilization: identification of FosB degron domains and implications for DeltaFosB stability. Eur J Neurosci. 2007;25:3009-19. (Pubitemid 46888818)
-
(2007)
European Journal of Neuroscience
, vol.25
, Issue.10
, pp. 3009-3019
-
-
Carle, T.L.1
Ohnishi, Y.N.2
Ohnishi, Y.H.3
Alibhai, I.N.4
Wilkinson, M.B.5
Kumar, A.6
Nestler, E.J.7
-
143
-
-
9744268957
-
DeltafosB: A molecular switch for long-term adaptation in the brain
-
DOI 10.1016/j.molbrainres.2004.05.014, PII S0169328X04002281, Neurogenomics
-
McClung C, Ulery P, Perrotti L, Zachariou V, Berton O, Nestler E. DeltaFosB: a molecular switch for long-term adaptation in the brain. Brain Res Mol Brain Res. 2004;132:146-54. (Pubitemid 39586757)
-
(2004)
Molecular Brain Research
, vol.132
, Issue.2
, pp. 146-154
-
-
McClung, C.A.1
Ulery, P.G.2
Perrotti, L.I.3
Zachariou, V.4
Berton, O.5
Nestler, E.J.6
-
144
-
-
78650418319
-
Long-term voluntary wheel running is rewarding and produces plasticity in the mesolimbic reward pathway
-
Greenwood BN, Foley TE, Le TV, Strong PV, Loughridge AB, Day HE, Fleshner M. Long-term voluntary wheel running is rewarding and produces plasticity in the mesolimbic reward pathway. Behav Brain Res. 2010;217:354-62.
-
(2010)
Behav Brain Res
, vol.217
, pp. 354-362
-
-
Greenwood, B.N.1
Foley, T.E.2
Le, T.V.3
Strong, P.V.4
Loughridge, A.B.5
Day, H.E.6
Fleshner, M.7
-
145
-
-
0027992668
-
Induction of a long-lasting AP-1 complex composed of altered fos-like proteins in brain by chronic cocaine and other chronic treatments
-
DOI 10.1016/0896-6273(94)90061-2
-
Hope BT, Nye HE, Kelz MB, Self DW, Iadarola MJ, Nakabeppu Y, Duman RS, Nestler EJ. Induction of a long-lasting AP-1 complex composed of altered Fos-like proteins in brain by chronic cocaine and other chronic treatments. Neuron. 1994;13:1235-44. (Pubitemid 24372141)
-
(1994)
Neuron
, vol.13
, Issue.5
, pp. 1235-1244
-
-
Hope, B.T.1
Nye, H.E.2
Kelz, M.B.3
Self, D.W.4
Iadarola, M.J.5
Nakabeppu, Y.6
Duman, R.S.7
Nestler, E.J.8
-
146
-
-
0029960788
-
Induction of chronic fos-related antigens in rat brain by chronic morphine administration
-
Nye HE, Nestler EJ. Induction of chronic Fos-related antigens in rat brain by chronic morphine administration. Mol Pharmacol. 1996;49:636-45. (Pubitemid 26117147)
-
(1996)
Molecular Pharmacology
, vol.49
, Issue.4
, pp. 636-645
-
-
Nye, H.E.1
Nestler, E.J.2
-
147
-
-
0031016618
-
Common neural substrates for the addictive properties of nicotine and cocaine
-
DOI 10.1126/science.275.5296.83
-
Pich EM, Pagliusi SR, Tessari M, Talabot-Ayer D, Hooft van Huijsduijnen R, Chiamulera C. Common neural substrates for the addictive properties of nicotine and cocaine. Science. 1997;275:83-6. (Pubitemid 27020313)
-
(1997)
Science
, vol.275
, Issue.5296
, pp. 83-86
-
-
Pich, E.M.1
Pagliusi, S.R.2
Tessari, M.3
Talabot-Ayer, D.4
Van Huijsduijnen, R.H.5
Chiamulera, C.6
-
148
-
-
0037107158
-
DeltaFosB regulates wheel running
-
Werme M, Messer C, Olson L, Gilden L, Thorén P, Nestler EJ, Brené S. Delta FosB regulates wheel running. J Neurosci. 2002;22:8133-8. (Pubitemid 35379119)
-
(2002)
Journal of Neuroscience
, vol.22
, Issue.18
, pp. 8133-8138
-
-
Werme, M.1
Messer, C.2
Olson, L.3
Gilden, L.4
Thoren, P.5
Nestler, E.J.6
Brene, S.7
-
149
-
-
55249122524
-
The influence of DeltaFosB in the nucleus accumbens on natural reward-related behavior
-
Wallace DL, Vialou V, Rios L, Carle-Florence TL, Chakravarty S, Kumar A, Graham DL, Green TA, Kirk A, Iñiguez SD, Perrotti LI, Barrot M, DiLeone RJ, Nestler EJ, Bolaños-Guzmán CA. The influence of DeltaFosB in the nucleus accumbens on natural reward-related behavior. J Neurosci. 2008;28:10272-7.
-
(2008)
J Neurosci
, vol.28
, pp. 10272-10277
-
-
Wallace, D.L.1
Vialou, V.2
Rios, L.3
Carle-Florence, T.L.4
Chakravarty, S.5
Kumar6
-
150
-
-
0030602817
-
A defect in nurturing in mice lacking the immediate early gene fosB
-
DOI 10.1016/S0092-8674(00)80101-4
-
Brown J, Ye H, Bronson R, Dikkes P, Greenberg M. A defect in nurturing in mice lacking the immediate early gene fosB. Cell. 1996;86:297-309. (Pubitemid 26286112)
-
(1996)
Cell
, vol.86
, Issue.2
, pp. 297-309
-
-
Brown, J.R.1
Ye, H.2
Bronson, R.T.3
Dikkes, P.4
Greenberg, M.E.5
-
151
-
-
0030885427
-
FosB mutant mice: Loss of chronic cocaine induction of Fos-related proteins and heightened sensitivity to cocaine's psychomotor and rewarding effects
-
DOI 10.1073/pnas.94.19.10397
-
Hiroi N, Brown JR, Haile CN, Ye H, Greenberg ME, Nestler EJ. FosB mutant mice: loss of chronic cocaine induction of Fos-related proteins and heightened sensitivity to cocaine's psychomotor and rewarding effects. Proc Natl Acad Sci USA. 1997;94:10397-402. (Pubitemid 27407053)
-
(1997)
Proceedings of the National Academy of Sciences of the United States of America
, vol.94
, Issue.19
, pp. 10397-10402
-
-
Hiroi, N.1
Brown, J.R.2
Haile, C.N.3
Ye, H.4
Greenberg, M.E.5
Nestler, E.J.6
-
152
-
-
31544439898
-
An essential role for DeltaFosB in the nucleus accumbens in morphine action
-
DOI 10.1038/nn1636, PII NN1636
-
Zachariou V, Bolanos CA, Selley DE, Theobald D, Cassidy MP, Kelz MB, Shaw-Lutchman T, Berton O, Sim-Selley LJ, Dileone RJ, Kumar A, Nestler EJ. An essential role for DeltaFosB in the nucleus accumbens in morphine action. Nat Neurosci. 2006;9:205-11. (Pubitemid 43164543)
-
(2006)
Nature Neuroscience
, vol.9
, Issue.2
, pp. 205-211
-
-
Zachariou, V.1
Bolanos, C.A.2
Selley, D.E.3
Theobald, D.4
Cassidy, M.P.5
Kelz, M.B.6
Shaw-Lutchman, T.7
Berton, O.8
Sim-Selley, L.J.9
Dileone, R.J.10
Kumar, A.11
Nestler, E.J.12
-
153
-
-
0033575937
-
Expression of the transcription factor deltaFosB in the brain controls sensitivity to cocaine
-
Kelz MB, Chen J, Carlezon WA, Whisler K, Gilden L, Beckmann AM, Steffen C, Zhang YJ, Marotti L, Self DW, Tkatch T, Baranauskas G, Surmeier DJ, Neve RL, Duman RS, Nestler EJ, Picciotto MR. Expression of the transcription factor deltaFosB in the brain controls sensitivity to cocaine. Nature. 1997;401:272-6.
-
(1997)
Nature
, vol.401
, pp. 272-276
-
-
Kelz, M.B.1
Chen, J.2
Carlezon, W.A.3
Whisler, K.4
Gilden, L.5
Beckmann, A.M.6
Steffen, C.7
Zhang, Y.J.8
Marotti, L.9
Self, D.W.10
Tkatch, T.11
Baranauskas, G.12
Surmeier, D.J.13
Neve, R.L.14
Duman, R.S.15
Nestler, E.J.16
Picciotto, M.R.17
-
154
-
-
66349090545
-
Noninjurious mechanical ventilation activates a proinflammatory transcriptional program in the lung
-
Gharib S, Liles W, Klaff L, Altemeier W. Noninjurious mechanical ventilation activates a proinflammatory transcriptional program in the lung. Physiol Genomics. 2009;37:239-48.
-
(2009)
Physiol Genomics
, vol.37
, pp. 239-248
-
-
Gharib, S.1
Liles, W.2
Klaff, L.3
Altemeier, W.4
-
155
-
-
33746906686
-
The transcription factor DeltafosB is recruited by inflammatory pain
-
DOI 10.1111/j.1471-4159.2006.03970.x
-
Luis-Delgado O, Barrot M, Rodeau J, Ulery P, Freund-Mercier M, Lasbennes F. The transcription factor DeltaFosB is recruited by inflammatory pain. J Neurochem. 2006;98:1423-31. (Pubitemid 44200434)
-
(2006)
Journal of Neurochemistry
, vol.98
, Issue.5
, pp. 1423-1431
-
-
Luis-Delgado, O.E.1
Barrot, M.2
Rodeau, J.-L.3
Ulery, P.G.4
Freund-Mercier, M.-J.5
Lasbennes, F.6
-
156
-
-
71749115655
-
Quantitative AP-1 gene regulation by oxidative stress in the human retinal pigment epithelium
-
Chaum E, Yin J, Yang H, Thomas F, Lang J. Quantitative AP-1 gene regulation by oxidative stress in the human retinal pigment epithelium. J Cell Biochem. 2009;108:1280-91.
-
(2009)
J Cell Biochem
, vol.108
, pp. 1280-1291
-
-
Chaum, E.1
Yin, J.2
Yang, H.3
Thomas, F.4
Lang, J.5
-
157
-
-
6044230918
-
Molecular profiling of inflammatory breast cancer: Identification of a poor-prognosis gene expression signature
-
DOI 10.1158/1078-0432.CCR-04-0306
-
Bièche I, Lerebours F, Tozlu S, Espie M, Marty M, Lidereau R. Molecular profiling of inflammatory breast cancer: identification of a poor-prognosis gene expression signature. Clin Cancer Res. 2004;10:6789-95. (Pubitemid 39383027)
-
(2004)
Clinical Cancer Research
, vol.10
, Issue.20
, pp. 6789-6795
-
-
Bieche, I.1
Lerebours, F.2
Tozlu, S.3
Espie, M.4
Marty, M.5
Lidereau, R.6
-
158
-
-
0030014237
-
Expression of FosB during mouse development: Normal development of FosB knockout mice
-
Gruda MC, van Amsterdam J, Rizzo CA, Durham SK, Lira S, Bravo R. Expression of FosB during mouse development: normal development of FosB knockout mice. Oncogene. 1996;12:2177-85. (Pubitemid 26168427)
-
(1996)
Oncogene
, vol.12
, Issue.10
, pp. 2177-2185
-
-
Gruda, M.C.1
Van Amsterdam, J.2
Rizzo, C.A.3
Durham, S.K.4
Lira, S.5
Bravo, R.6
-
159
-
-
0033624587
-
Overexpression of DeltaFosB transcription factor(s) increases bone formation and inhibits adipogenesis
-
Sabatakos G, Sims NA, Chen J, Aoki K, Kelz MB, Amling M, Bouali Y, Mukhopadhyay K, Ford K, Nestler EJ, Baron R. Overexpression of DeltaFosB transcription factor(s) increases bone formation and inhibits adipogenesis. Nat Med. 2000;6:985-90.
-
(2000)
Nat Med
, vol.6
, pp. 985-990
-
-
Sabatakos, G.1
Sims, N.A.2
Chen, J.3
Aoki, K.4
Kelz, M.B.5
Amling, M.6
Bouali, Y.7
Mukhopadhyay, K.8
Ford, K.9
Nestler, E.J.10
Baron, R.11
-
160
-
-
70350215880
-
Mechanical stress induces Interleukin-11 expression to stimulate osteoblast differentiation
-
Kido S, Kuriwaka-Kido R, Imamura T, Ito Y, Inoue D, Matsumoto T. Mechanical stress induces Interleukin-11 expression to stimulate osteoblast differentiation. Bone. 2009;45:1125-32.
-
(2009)
Bone
, vol.45
, pp. 1125-1132
-
-
Kido, S.1
Kuriwaka-Kido, R.2
Imamura, T.3
Ito, Y.4
Inoue, D.5
Matsumoto, T.6
-
161
-
-
0034786751
-
Interleukin-11 induces osteoblast differentiation and acts synergistically with bone morphogenetic protein-2 in C3H10T1/2 cells
-
DOI 10.1089/107999001753124435
-
Suga K, Saitoh M, Fukushima S, Takahashi K, Nara H, Yasuda S, Yasuda S, Miyata K. Interleukin-11 induces osteoblast differentiation and acts synergistically with bone morphogenetic protein-2 in C3H10T1/2 cells. J Interferon Cytokine Res. 2001;21:695-707. (Pubitemid 32955700)
-
(2001)
Journal of Interferon and Cytokine Research
, vol.21
, Issue.9
, pp. 695-707
-
-
Suga, K.1
Saitoh, M.2
Fukushima, S.3
Takahashi, K.4
Nara, H.5
Yasuda, S.6
Miyata, K.7
-
162
-
-
77955420249
-
Synthesis and biological activity of a series of tetrasubstituted- imidazoles as P2X(7) antagonists
-
Gleave RJ, Walter DS, Beswick PJ, Fonfria E, Michel AD, Roman SA, Tang SP. Synthesis and biological activity of a series of tetrasubstituted-imidazoles as P2X(7) antagonists. Bioorg Med Chem Lett. 2010;20:4951-4.
-
(2010)
Bioorg Med Chem Lett
, vol.20
, pp. 4951-4954
-
-
Gleave, R.J.1
Walter, D.S.2
Beswick, P.J.3
Fonfria, E.4
Michel, A.D.5
Roman, S.A.6
Tang, S.P.7
-
163
-
-
77952105608
-
Synthesis and structure-activity relationships of a series of (1H-pyrazol-4-yl)acetamide antagonists of the P2X7 receptor
-
Chambers LJ, Stevens AJ, Moses AP, Michel AD, Walter DS, Davies DJ, Livermore DG, Fonfria E, Demont EH, Vimal M, Theobald PJ, Beswick PJ, Gleave RJ, Roman SA, Senger S. Synthesis and structure-activity relationships of a series of (1H-pyrazol-4-yl)acetamide antagonists of the P2X7 receptor. Bioorg Med Chem Lett. 2010;20:3161-4.
-
(2010)
Bioorg Med Chem Lett
, vol.20
, pp. 3161-3164
-
-
Chambers, L.J.1
Stevens, A.J.2
Moses, A.P.3
Michel, A.D.4
Walter, D.S.5
Davies, D.J.6
Livermore, D.G.7
Fonfria, E.8
Demont, E.H.9
Vimal, M.10
Theobald, P.J.11
Beswick, P.J.12
Gleave, R.J.13
Roman, S.A.14
Senger, S.15
-
164
-
-
77952106771
-
Discovery of 2-chloro-N-((4, 4-difluoro-1-hydroxycyclohexyl) methyl)-5-(5-fluoropyrimidin-2-yl)benzamide as a potent and CNS penetrable P2X7 receptor antagonist
-
Chen X, Pierce B, Naing W, Grapperhaus ML, Phillion DP. Discovery of 2-chloro-N-((4, 4-difluoro-1-hydroxycyclohexyl) methyl)-5-(5-fluoropyrimidin-2- yl)benzamide as a potent and CNS penetrable P2X7 receptor antagonist. Bioorg Med Chem Lett. 2010;20:3107-11.
-
(2010)
Bioorg Med Chem Lett
, vol.20
, pp. 3107-3111
-
-
Chen, X.1
Pierce, B.2
Naing, W.3
Grapperhaus, M.L.4
Phillion, D.P.5
-
165
-
-
71749104255
-
Synthesis and structure-activity relationships of pyrazolodiazepine derivatives as human P2X7 receptor antagonists
-
Lee JY, Yu J, Cho WJ, Ko H, Kim YC. Synthesis and structure-activity relationships of pyrazolodiazepine derivatives as human P2X7 receptor antagonists. Bioorg Med Chem Lett. 2009;19:6053-8.
-
(2009)
Bioorg Med Chem Lett
, vol.19
, pp. 6053-6058
-
-
Lee, J.Y.1
Yu, J.2
Cho, W.J.3
Ko, H.4
Kim, Y.C.5
-
166
-
-
38149132392
-
Synthesis and structure-activity relationship studies of tyrosine-based antagonists at the human P2X7 receptor
-
Lee G, Joshi B, Chen W, Jeong L, Moon H, Jacobson K, Kim Y. Synthesis and structure-activity relationship studies of tyrosine-based antagonists at the human P2X7 receptor. Bioorg Med Chem Lett. 2008;18:571-5.
-
(2008)
Bioorg Med Chem Lett
, vol.18
, pp. 571-575
-
-
Lee, G.1
Joshi, B.2
Chen, W.3
Jeong, L.4
Moon, H.5
Jacobson, K.6
Kim, Y.7
-
167
-
-
34447291072
-
Induction of deltaFosB in the Periaqueductal Gray by Stress Promotes Active Coping Responses
-
DOI 10.1016/j.neuron.2007.06.033, PII S0896627307004904
-
Berton O, Covington HE, Ebner K, Tsankova NM, Carle TL, Ulery P, Bhonsle A, Barrot M, Krishnan V, Singewald GM, Singewald N, Birnbaum S, Neve RL, Nestler EJ. Induction of deltaFosB in the periaqueductal gray by stress promotes active coping responses. Neuron. 2007;55:289-300. (Pubitemid 47048913)
-
(2007)
Neuron
, vol.55
, Issue.2
, pp. 289-300
-
-
Berton, O.1
Covington III, H.E.2
Ebner, K.3
Tsankova, N.M.4
Carle, T.L.5
Ulery, P.6
Bhonsle, A.7
Barrot, M.8
Krishnan, V.9
Singewald, G.M.10
Singewald, N.11
Birnbaum, S.12
Neve, R.L.13
Nestler, E.J.14
-
168
-
-
4544309949
-
7 receptor
-
DOI 10.1074/jbc.M313902200
-
Gu B, Sluyter R, Skarratt K, Shemon A, Dao-Ung L, Fuller S, Barden J, Clarke A, Petrou S, Wiley J. An Arg307 to Gln polymorphism within the ATP-binding site causes loss of function of the human P2X7 receptor. J Biol Chem. 2004;279:31287-95. (Pubitemid 39037794)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.30
, pp. 31287-31295
-
-
Gu, B.J.1
Sluyter, R.2
Skarratt, K.K.3
Shemon, A.N.4
Dao-Ung, L.-P.5
Fuller, S.J.6
Barden, J.A.7
Clarke, A.L.8
Petrou, S.9
Wiley, J.S.10
-
169
-
-
0037931836
-
An Ile-568 to Asn polymorphism prevents normal trafficking and function of the human P2X7 receptor
-
Wiley J, Dao-Ung L, Li C, Shemon A, Gu B, Smart M, Fuller S, Barden J, Petrou S, Sluyter R. An Ile-568 to Asn polymorphism prevents normal trafficking and function of the human P2X7 receptor. J Biol Chem. 2003;278:17108-13.
-
(2003)
J Biol Chem
, vol.278
, pp. 17108-17113
-
-
Wiley, J.1
Dao-Ung, L.2
Li, C.3
Shemon, A.4
Gu, B.5
Smart, M.6
Fuller, S.7
Barden, J.8
Petrou, S.9
Sluyter, R.10
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