Glu496Ala polymorphism of human P2x7 receptor does not affect its electrophysiological phenotype

American Journal of Physiology - Cell Physiology

Volumn 284, Issue 3 53-3, 2003, Pages

  Boldt, Wolfgang ^a   Klapperstück, Manuela ^a   Büttner, Cora ^b   Sadtler, Sven ^b   Schmalzing, Günther ^b   Markwardt, Fritz ^a  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^b RWTH AACHEN UNIVERSITY   (Germany)

Author keywords

HEK293 celss; Kinetics; Permeation; Whole cell current; Xenopus oocytes

Indexed keywords

ADENOSINE TRIPHOSPHATE; ALANINE; ETHIDIUM; GLUTAMINE; ION CHANNEL; PURINE P2X RECEPTOR; PURINE P2X7 RECEPTOR; UNCLASSIFIED DRUG; CATION; PURINE P2 RECEPTOR;

AMINO ACID SUBSTITUTION; AMPLITUDE MODULATION; ANIMAL CELL; APOPTOSIS; ARTICLE; B LYMPHOCYTE; BINDING KINETICS; CATION TRANSPORT; CELL ACTIVITY; CHANNEL GATING; CONTROLLED STUDY; ELECTROPHYSIOLOGY; GENE MUTATION; GENETIC POLYMORPHISM; HUMAN; LYMPHOCYTE FUNCTION; MATHEMATICAL ANALYSIS; MICROELECTRODE; NONHUMAN; NUCLEOTIDE SEQUENCE; OOCYTE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN STRUCTURE; RECEPTOR BINDING; TRANSPORT KINETICS; VOLTAGE CLAMP; XENOPUS; AMINO ACID SEQUENCE; ANIMAL; CELL CULTURE; CELL MEMBRANE; CELL MEMBRANE PERMEABILITY; CELL MEMBRANE POTENTIAL; DOSE RESPONSE; DRUG EFFECT; EUKARYOTIC CELL; FEMALE; GENETICS; KINETICS; METABOLISM; MUTATION; XENOPUS LAEVIS;

ANIMALIA;

ADENOSINE TRIPHOSPHATE; ALANINE; AMINO ACID SEQUENCE; ANIMALS; CATIONS; CELL MEMBRANE; CELL MEMBRANE PERMEABILITY; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; EUKARYOTIC CELLS; FEMALE; GLUTAMINE; HUMANS; ION CHANNELS; KINETICS; MEMBRANE POTENTIALS; MUTATION; OOCYTES; PHENOTYPE; POLYMORPHISM, GENETIC; RECEPTORS, PURINERGIC P2; XENOPUS LAEVIS;

EID: 0037362564     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.00042.2002     Document Type: Article

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