A Glu-496 to Ala Polymorphism Leads to Loss of Function of the Human P2X7 Receptor

Journal of Biological Chemistry

Volumn 276, Issue 14, 2001, Pages 11135-11142

  Gu, Ben J ^a   Zhang, Weiyi ^a   Worthington, Rebecca A ^a   Sluyter, Ronald ^a   Dao Ung, Phuong ^a   Petrou, Steven ^b   Barden, Julian A ^a   Wiley, James S ^a,c  

^a UNIVERSITY OF SYDNEY   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c NEPEAN HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CELLS; DNA; GENES; IMMUNOLOGY;

APOPTOSIS; CARBOXYL-TERMINAL TAIL; POLYMORPHISM; TRANSFECTION EXPERIMENTS;

BIOCHEMISTRY;

ALANINE; GAMMA INTERFERON; GLUTAMIC ACID; PURINE P2X RECEPTOR; PURINE P2X7 RECEPTOR; PURINE P2 RECEPTOR;

APOPTOSIS; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DNA POLYMORPHISM; DNA SEQUENCE; GENETIC ANALYSIS; HUMAN; HUMAN CELL; IMMUNE SYSTEM; IMMUNOFLUORESCENCE; LYMPHOCYTE; MACROPHAGE; MONOCYTE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RECEPTOR INTRINSIC ACTIVITY; CELL CULTURE; GENETIC POLYMORPHISM; GENETICS; METABOLISM; MONONUCLEAR CELL; POINT MUTATION; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION;

ALANINE; CELLS, CULTURED; GLUTAMIC ACID; HUMANS; LEUKOCYTES, MONONUCLEAR; POINT MUTATION; POLYMORPHISM, GENETIC; RECEPTORS, PURINERGIC P2; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0035815630     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M010353200     Document Type: Article

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