A comparative study of interleukin-1β production and P2x7 expression after Atp stimulation by peripheral blood mononuclear cells isolated from rheumatoid arthritis patients and normal healthy controls

Inflammation

Volumn 31, Issue 2, 2008, Pages 84-90

  Al Shukaili, Ahmed ^a   Al Kaabi, Juma ^b   Hassan, Batool ^b  

^a SULTAN QABOOS UNIVERSITY   (Oman)

^b SULTAN QABOOS UNIVERSITY HOSPITAL   (Oman)

Author keywords

ATP; IL 1 ; P2X7 receptors; RA

Indexed keywords

ADENOSINE TRIPHOSPHATE; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; PURINERGIC P2X7 RECEPTOR;

ADULT; ARTICLE; BLOOD SAMPLING; CELL ISOLATION; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; MALE; PERIPHERAL BLOOD MONONUCLEAR CELL; PROTEIN EXPRESSION; RHEUMATOID ARTHRITIS; UPREGULATION;

ADENOSINE TRIPHOSPHATE; ADULT; ANTIGENS, CD14; ARTHRITIS, RHEUMATOID; CASE-CONTROL STUDIES; CELLS, CULTURED; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; HUMANS; INTERLEUKIN-1BETA; LEUKOCYTES, MONONUCLEAR; LIPOPOLYSACCHARIDES; MALE; MIDDLE AGED; RECEPTORS, PURINERGIC P2; TIME FACTORS;

EID: 40749157181     PISSN: 03603997     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10753-007-9052-0     Document Type: Article

References (30)

1. Alamanos, Y., P. Voulgari, and A. Drosos. 2006. Incidence and prevalence of rheumatoid Arthritis, based on the 1987 American College of Rheumatology Criteria: a systematic review. Semin. Arthritis. Rheum. 36:182-188.
2. Sewell, K., and D. E. Trentham. 1993. Pathogenesis of rheumatoid arthritis. Lancet 34:283-286.
3. Dinarello, C. A. 1996. Biological basis for interleukin-1 in disease. Blood 87:2095-2147.
4. Kostura, M. J., M. J. Tocci, G. Limjuco, J. Chin, P. Cameron, A. G. Hillman, N. A. Chartrain, and J. A. Schmidt. 1989. Identification of a monocytes specific pre-interleukin-1 convertase activity. Proc. Natl. Acad. Sci. USA 86:5227-5231.
5. Ferrari, D., M. Villalba, P. Chiozzi, S. Falzoni, P. Ricciardi- Castagnoli, and F. Di Virgilio. 1996. Mouse microglial cells express a plasma membrane pore gated by extracellular ATP. J. Immunol. 156:1531-1539.
6. Ferrari, D., P. Chiozzi, S. Falzoni, M. Dal Susino, L. Melchiorri, O. R. Baricordi, and F. Di Virgilio. 1997. Extracellular ATP triggers IL-1 beta release by activating the purinergic P2Z receptor of human macrophages. J. Immunol. 159:1451-1458.
7. Perregaux, D. G., and C. A. Gabel. 1998. Post-translational processing of murine IL-1: evidence that ATP-induced release of IL-1 alpha and IL-1 beta occurs via a similar mechanism. J. Immunol. 160:2469-2477.
8. Laliberte, R., J. Eggler, and C. A. Gabel. 1999. ATP treatment of human monocytes promotes caspase-1 maturation and externalization. J. Biol. Chem. 274:36944-36951.
9. Perregaux, D. G., P. McNiff, R. Laliberte, M. Conklyn, and C. A. Gabel. 2000. ATP acts as an agonist to promote stimulus-induced secretion of IL-1 beta and IL-18 in human blood. J. Immunol. 165:4615-4623.
10. Mehta, V. B., J. Hart, and M. D. Wewers. 2001. ATP-stimulated release of interleukin (IL)-1β and IL-18 requires priming by lipopolysaccharide and is independent of caspase-1 cleavage. J. Biol. Chem. 276:3820-3826.
11. Ferrari, D., C. Pizzirani, E. Adinolfi, R. M. Lemoli, A. Curti, M. Idzko, E. Panther, and F. Di Virgilio. 2006. The P2X7 receptor: a key player in IL-1 processing and release. J. Immunol. 176:3877-3883.
12. Gu, B. J., W. Y. Zhang, L. J. Bendall, I. P. Chessell, G. N. Buell, and J. S. Wiley. 2000. Expression of P2X7 purinoceptors on human lymphocytes and monocyes: Evidence for non-functional P2X7 receptors. Am. J. Physiol. 279:C1189-C1197.
13. 7 channel. Am. J. Physiol. 275:C1224-C1231.
14. 7 receptor activation. J. Immunol. 173:1202-1208.
15. Arnett, F. C., S. M. Edworthy, D. A. Bloch, D. J. McShane, J. F. Fries, N. S. Cooper, L. A. Healey, S. R. Kaplan, M. H. Liang, H. S. Luthra et al. 1988. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum. 31:315-324.
16. 7 receptor impairs ATP-induced IL-1 beta release from human monocytes. J. Immunol. 172:3399-3405.
17. Franco-Martinez, S., P. Nino-Moreno, S. Bernal-Silva, L. Baranda, M. Rocha-Meza, L. Portales-Cervantes, E. Layseca-Espinosa, R. Gonzalez-Amaro, and D. Portales-Perez. 2006. Expression and function of the purinergic receptor P2X7 in patients with pulmonary tuberculosis. Clin. Exp. Immunol. 46:253-261.
18. Wiley, J. S., L. P. Dao-Ung, B. J. Gu, R. Sluyter, A. N. Shemon, C. Li, J. Taper, J. Gallo, and A. Manoharan. 2002. A loss-of-function polymorphic mutation in the cytolytic P2X7 receptor gene and chronic lymphocytic leukaemia: a molecular study. Lancet 359:1114-1119.
19. Gu, B. J., W. Zhang, R. A. Worthington, R. Sluyter, P. Dao-Ung, S. Petrou, J. A. Barden, and J. S. Wiley. 2001. A Glu-496 to Ala polymorphism leads to loss of function of the human P2X7 receptor. J. Biol. Chem. 276:11135-11142.
20. Gu, B. J., R. Sluyter, K. K. Skarratt, A. N. Shemon, L. P. Dao-Ung, S. J. Fuller, J. A. Barden, A. L. Clarke, S. Petrou, and J. S. Wiley. 2004. An Arg307 to Gln polymorphism within the ATP-binding site causes loss of function of the human P2X7 receptor. J. Biol. Chem. 279:31287-31295.
21. Skarratt, K. K., S. J. Fuller, R. Sluyter, L. P. Dao-Ung, B. J. Gu, and J. S. Wiley. 2005. A 5′ intronic splice site polymorphism leads to a null allele of the P2X7 gene in 1-2% of the Caucasian population. FEBS Lett. 579:2675-2678.
22. Cabrini, G., S. Falzoni, S. L. Forchap, P. Pellegatti, A. Balboni, P. Agostini, A. Cuneo, G. Castoldi, O. R. Baricordi, and F. Di Virgilio. 2005. A His-155 to Tyr polymorphism confers gain-of-function to the human P2X7 receptor of human leukemic lymphocytes. J. Immunol. 175:82-89.
23. Saunders, B. M., S. L. Fernando, R. Sluyter, W. J. Britton, and J. S. Wiley. 2003. A loss of function polymorphism in the human P2X7 receptor abolishes ATP-mediated killing of mycobacteria. J. Immunol. 171:5442-5446.
24. Fernando, S. L., B. M. Saunders, R. Sluyter, K. K. Skarratt, J. S. Wiley, and W. J. Britton. 2005. Gene dosage determines the negative effect of polymorphic alleles of the P2X7 receptor on adenosine triphosphate-mediated killing of mycobacteria by human macrophages. J. Infect. Dis. 192:149-155.
25. Fernando, S. L., B. M. Saunders, R. Sluyter, K. K. Skarratt, H. Goldberg, G. B. Marks, J. S. Wiley, and W. J. Britton. 2007. A polymorphism in the P2X7 gene increases susceptibility to extrapulmonary tuberculosis. Am. J. Respir. Crit. Care Med. 175:360-366.
26. Perregaux, D. G., and C. A. Gabel. 1994. Interleukin-1β maturation and release in response to ATP and nigericin: evidence that potassium depletion mediated by these agents is a necessary and common feature of their activity. J. Biol. Chem. 269:15195-15203.
27. Perregaux, D. G., and C. A. Gabel. 1998. Human monocytes stimulus-coupled IL-1β posttranslational processing: Modulation via monovalent cations. Am. J. Physiol. 275:C1538-C1547.
28. Blanchard, D. K., S. McMillen, and J. Y. Djeu. 1991. IFN-gamma enhance sensitivity of human macrophages to extracellular ATP-mediated lysis. J. Immunol. 147:2579-2585.
29. Turner, C. M., F. W. Tam, P. C. Lai, R. M. Tarzi, G. Burnstock, C. D. Pusey, H. T. Cook, and R. J. Unwin. 2007. Increased expression of the pro-apoptotic ATP-sensitive P2X7 receptor in -experimental and human glomerulonephritis. Nephrol. Dial. Transplant. 22:386-395.
30. Feng, Y. H., L. Wang, Q. Wang, X. Li, R. Zeng, and G. I. Gorodeski. 2005. ATP stimulates GRK-3 phosphorylation and beta-arrestin-2-dependent internalization of P2X7 receptor. Am. J. Physiol. Cell. Physiol. 288:C1342-C1356.