Mutation of putative N-linked glycosylation sites on the human nucleotide receptor P2X7 reveals a key residue important for receptor function

Biochemistry

Volumn 49, Issue 22, 2010, Pages 4611-4619

  Lenertz, Lisa Y ^a   Wang, Ziyi ^a   Guadarrama, Arturo ^a   Hill, Lindsay M ^a   Gavala, Monica L ^a   Bertics, Paul J ^a  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATION CHANNELS; CELL SURFACE EXPRESSION; CONSENSUS SEQUENCE; EXTRACELLULAR ATP; GLYCOSIDASES; GLYCOSYLATED; HUMAN RECEPTORS; IMMUNE CELLS; INTERLEUKIN-1; ISOFORMS; LIGAND BINDING; LIVE CELL; N-LINKED; N-LINKED GLYCOSYLATION; NUCLEOTIDE RECEPTOR; P2X RECEPTORS; P90 RIBOSOMAL S6 KINASE; PHORBOL ESTERS; PNGASE F; PORE FORMATION; PROTEINASE K; REACTIVE OXYGEN SPECIES; RECEPTOR ACTIVITY; RECEPTOR TRAFFICKING; THERAPEUTIC TARGETS; TISSUE INJURY; TUNICAMYCIN;

BIOCHEMISTRY; CELL MEMBRANES; ENZYME ACTIVITY; ESTERS; MACROPHAGES; NUCLEOTIDES; OXYGEN; PHOSPHORYLATION; SYNTHESIS (CHEMICAL); TRANSCRIPTION FACTORS;

GLYCOSYLATION;

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; GLYCOSIDASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHORBOL ESTER; PROTEIN P90; PURINERGIC P2X7 RECEPTOR; PURINERGIC RECEPTOR BLOCKING AGENT; S6 KINASE; TUNICAMYCIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; GLYCOSYLATION; HUMAN; HUMAN CELL; MACROPHAGE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM;

AMINO ACID SEQUENCE; ANIMALS; ASPARAGINE; CELL LINE; CERCOPITHECUS AETHIOPS; CONSERVED SEQUENCE; COS CELLS; DOWN-REGULATION; EXTRACELLULAR SPACE; GLYCOSYLATION; HUMANS; MICE; MOLECULAR SEQUENCE DATA; POINT MUTATION; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN TRANSPORT; RECEPTORS, PURINERGIC P2; SIGNAL TRANSDUCTION;

EID: 77953106276     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi902083n     Document Type: Article

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