Systemic administration of an antagonist of the ATP-sensitive receptor P2X7 improves recovery after spinal cord injury

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 30, 2009, Pages 12489-12493

  Peng, Weiguo ^a   Cotrina, Maria L ^a   Han, Xiaoning ^a   Yu, Hongmei ^a   Bekar, Lane ^a   Blum, Livnat ^a   Takano, Takahiro ^a   Tian, Guo Feng ^a   Goldman, Steven A ^a   Nedergaard, Maiken ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

Astrocytes; Inflammation; Microglia; Motor neurons; Purinergic signaling

Indexed keywords

ADENOSINE TRIPHOSPHATE; BRILLIANT BLUE; PURINERGIC P2X7 RECEPTOR; PURINERGIC RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BLOOD BRAIN BARRIER; CONTROLLED STUDY; EXCITOTOXICITY; FEASIBILITY STUDY; FOOD COLOR; INFLAMMATION; MICROGLIA; MOTOR PERFORMANCE; NEUROPROTECTION; NEUTROPHIL CHEMOTAXIS; NONHUMAN; OBSERVATION; PRIORITY JOURNAL; RAT; SPINAL CORD INJURY; SPINAL CORD NERVE CELL; SPINE INJURY;

ADENOSINE TRIPHOSPHATE; ANIMALS; DISEASE MODELS, ANIMAL; HUMANS; INDICATORS AND REAGENTS; NEUROPROTECTIVE AGENTS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, PURINERGIC P2; RECOVERY OF FUNCTION; ROSANILINE DYES; SPINAL CORD; SPINAL CORD INJURIES; TIME FACTORS;

RATTUS;

EID: 68149157440     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0902531106     Document Type: Article

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