A polymorphism in the P2X7 gene increases susceptibility to extrapulmonary tuberculosis

American Journal of Respiratory and Critical Care Medicine

Volumn 175, Issue 4, 2007, Pages 360-366

  Fernando, Suran L ^a   Saunders, Bernadette M ^a,b   Sluyter, Ronald ^b   Skarratt, Kristen K ^b   Goldberg, Hazel ^c   Marks, Guy B ^d,e   Wiley, James S ^b   Britton, Warwick J ^a,b,f  

^a CENTENARY INSTITUTE   (Australia)

^b UNIVERSITY OF SYDNEY   (Australia)

^c ROYAL PRINCE ALFRED HOSPITAL   (Australia)

^d UNIVERSITY OF NEW SOUTH WALES   (Australia)

^e WOOLCOCK INSTITUTE OF MEDICAL RESEARCH   (Australia)

^f CENTENARY INSTITUTE   (Australia)

Author keywords

Genes; Macrophage; P2X7; Susceptibility; Tuberculosis

Indexed keywords

ADENOSINE TRIPHOSPHATE; PROTEIN DERIVATIVE; PROTEIN P2X7; UNCLASSIFIED DRUG; PURINE P2 RECEPTOR; PURINE P2X7 RECEPTOR;

ADULT; ALLELE; APOPTOSIS; ARTICLE; BACTERICIDAL ACTIVITY; CASE CONTROL STUDY; COHORT ANALYSIS; CONFIDENCE INTERVAL; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE PREDISPOSITION; DNA POLYMORPHISM; EXTRAPULMONARY TUBERCULOSIS; FEMALE; GENOTYPE; HOMOZYGOTE; HUMAN; MACROPHAGE; MAJOR CLINICAL STUDY; MALE; MYCOBACTERIUM; PREVALENCE; PRIORITY JOURNAL; RISK; RISK ASSESSMENT; AUSTRALIA; GENETIC PREDISPOSITION; GENETICS; IMMUNOLOGY; MIDDLE AGED; MYCOBACTERIUM TUBERCULOSIS; PHYSIOLOGY; SINGLE NUCLEOTIDE POLYMORPHISM; SOUTHEAST ASIA; TUBERCULOSIS;

ADENOSINE TRIPHOSPHATE; ADULT; ALLELES; APOPTOSIS; ASIA, SOUTHEASTERN; AUSTRALIA; CASE-CONTROL STUDIES; COHORT STUDIES; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; MACROPHAGES; MALE; MIDDLE AGED; MYCOBACTERIUM TUBERCULOSIS; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, PURINERGIC P2; TUBERCULOSIS;

EID: 33847052870     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.200607-970OC     Document Type: Article

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