메뉴 건너뛰기




Volumn 29, Issue 4, 2009, Pages 335-345

Modulation of the ATP-lnduced release and processing of IL-1Β in microglial cells

Author keywords

Cytoskeletal proteins; IL 1 ; Lysophospholipids; Microglia; P2X7 receptor

Indexed keywords

ADENOSINE TRIPHOSPHATE; COLCHICINE; INTERLEUKIN 1BETA; LYSOPHOSPHOLIPID; PURINERGIC P2X7 RECEPTOR;

EID: 69149106095     PISSN: 10408401     EISSN: None     Source Type: Journal    
DOI: 10.1615/critrevimmunol.v29.i4.40     Document Type: Review
Times cited : (54)

References (73)
  • 1
    • 0036847816 scopus 로고    scopus 로고
    • Microglia as neuroprotective, immunocompetent cells of the CNS
    • Streit WJ. Microglia as neuroprotective, immunocompetent cells of the CNS. Glia. 2002;40: 133-9.
    • (2002) Glia , vol.40 , pp. 133-139
    • Streit, W.J.1
  • 2
    • 19744380563 scopus 로고    scopus 로고
    • Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo
    • Nimmerjahn A, Kirchhoff F, Helmchen F. Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo. Science. 2005;308:1314-8.
    • (2005) Science , vol.308 , pp. 1314-1318
    • Nimmerjahn, A.1    Kirchhoff, F.2    Helmchen, F.3
  • 4
    • 22244458574 scopus 로고    scopus 로고
    • Fetler L, Amigorena S. Neuroscience. Brain under surveillance: the microglia patrol. Science. 2005;309:392-3.
    • Fetler L, Amigorena S. Neuroscience. Brain under surveillance: the microglia patrol. Science. 2005;309:392-3.
  • 5
    • 0036849018 scopus 로고    scopus 로고
    • Microglia as a source and target of cytokines
    • Hanisch UK. Microglia as a source and target of cytokines. Glia 2002;40:140-55.
    • (2002) Glia , vol.40 , pp. 140-155
    • Hanisch, U.K.1
  • 6
    • 33747463996 scopus 로고    scopus 로고
    • Microglia biology in health and disease
    • Garden GA, Moller T. Microglia biology in health and disease. J Neuroimmune Pharmacol. 2006;1:127-37.
    • (2006) J Neuroimmune Pharmacol , vol.1 , pp. 127-137
    • Garden, G.A.1    Moller, T.2
  • 7
    • 33747494572 scopus 로고    scopus 로고
    • Microglia as a pharmacological target in infectious and inflammatory diseases of the brain
    • Rock RB, Peterson PK. Microglia as a pharmacological target in infectious and inflammatory diseases of the brain. J Neuroimmune Pharmacol. 2006;1:117-26.
    • (2006) J Neuroimmune Pharmacol , vol.1 , pp. 117-126
    • Rock, R.B.1    Peterson, P.K.2
  • 9
    • 58149181978 scopus 로고    scopus 로고
    • Fibrillar amyloid-βpeptides activate microglia via TLR2: Implications for Alzheimer's disease
    • Jana M, Palencia CA, Pahan K. Fibrillar amyloid-βpeptides activate microglia via TLR2: implications for Alzheimer's disease. J Immunol. 2008;181:7254-62.
    • (2008) J Immunol , vol.181 , pp. 7254-7262
    • Jana, M.1    Palencia, C.A.2    Pahan, K.3
  • 11
    • 0029997484 scopus 로고    scopus 로고
    • Role of microglia and host prion protein in neurotoxicity of a prion protein fragment
    • Brown DR, Schmidt B, Kretzschmar HA. Role of microglia and host prion protein in neurotoxicity of a prion protein fragment. Nature. 1996;380:345-7.
    • (1996) Nature , vol.380 , pp. 345-347
    • Brown, D.R.1    Schmidt, B.2    Kretzschmar, H.A.3
  • 12
    • 2942598764 scopus 로고    scopus 로고
    • Interleukin-1β and interleukin-18: Regulation and activity in local inflammation
    • Delaleu N, Bickel M. Interleukin-1β and interleukin-18: regulation and activity in local inflammation. Periodontol 2000 2004; 35:42-52.
    • (2004) Periodontol 2000 , vol.35 , pp. 42-52
    • Delaleu, N.1    Bickel, M.2
  • 13
    • 0033377587 scopus 로고    scopus 로고
    • Cytokines as endogenous pyrogens
    • Dinarello CA. Cytokines as endogenous pyrogens. J Infect Dis 1999; 179 Suppl 2:S294-304.
    • (1999) J Infect Dis , vol.179 , Issue.SUPPL. 2
    • Dinarello, C.A.1
  • 14
    • 45249116745 scopus 로고    scopus 로고
    • Interleukin-1β: A bridge between inflammation and excitotoxicity?
    • Fogal B, Hewett SJ. Interleukin-1β: a bridge between inflammation and excitotoxicity? J Neurochem 2008; 106:1-23.
    • (2008) J Neurochem , vol.106 , pp. 1-23
    • Fogal, B.1    Hewett, S.J.2
  • 16
    • 0029979369 scopus 로고    scopus 로고
    • Biologic basis for interleukin-1 in disease
    • Dinarello CA. Biologic basis for interleukin-1 in disease. Blood 1996; 87:2095-147.
    • (1996) Blood , vol.87 , pp. 2095-2147
    • Dinarello, C.A.1
  • 17
    • 0036398446 scopus 로고    scopus 로고
    • The IL-1 family and inflammatory diseases
    • Dinarello CA. The IL-1 family and inflammatory diseases. Clin Exp Rheumatol. 2002;20:S1-13.
    • (2002) Clin Exp Rheumatol , vol.20
    • Dinarello, C.A.1
  • 18
    • 15844393942 scopus 로고    scopus 로고
    • Activation of the native 45-kDa precursor form of interleukin-1-converting enzyme
    • Yamin TT, Ayala JM, Miller DK. Activation of the native 45-kDa precursor form of interleukin-1-converting enzyme. J Biol Chem. 1996;271: 13273-82.
    • (1996) J Biol Chem , vol.271 , pp. 13273-13282
    • Yamin, T.T.1    Ayala, J.M.2    Miller, D.K.3
  • 19
    • 0034192082 scopus 로고    scopus 로고
    • Kinetics and mechanism of ATP-dependent IL-1β release from microglial cells
    • Sanz JM, Di Virgilio F. Kinetics and mechanism of ATP-dependent IL-1β release from microglial cells. J Immunol. 2000;164:4893-8.
    • (2000) J Immunol , vol.164 , pp. 4893-4898
    • Sanz, J.M.1    Di Virgilio, F.2
  • 20
    • 0031054641 scopus 로고    scopus 로고
    • Purinergic modulation of interleukin-1β release from microglial cells stimulated with bacterial endotoxin
    • Ferrari D, Chiozzi P, Falzoni S, Hanau S, Di Virgilio F. Purinergic modulation of interleukin-1β release from microglial cells stimulated with bacterial endotoxin. J Exp Med. 1997;185:579-82.
    • (1997) J Exp Med , vol.185 , pp. 579-582
    • Ferrari, D.1    Chiozzi, P.2    Falzoni, S.3    Hanau, S.4    Di Virgilio, F.5
  • 21
    • 37449011204 scopus 로고    scopus 로고
    • In vitro and in vivo evidence for a role of the P2X7 receptor in the release of IL-1β in the murine brain
    • Mingam R, De Smedt V, Amedee T, Bluthe RM, Kelley KW, Dantzer R, Laye S. In vitro and in vivo evidence for a role of the P2X7 receptor in the release of IL-1β in the murine brain. Brain Behav Immun. 2008;22:234-44.
    • (2008) Brain Behav Immun , vol.22 , pp. 234-244
    • Mingam, R.1    De Smedt, V.2    Amedee, T.3    Bluthe, R.M.4    Kelley, K.W.5    Dantzer, R.6    Laye, S.7
  • 27
    • 0036788971 scopus 로고    scopus 로고
    • Molecular physiology of P2X receptors
    • North RA. Molecular physiology of P2X receptors. Physiol Rev. 2002;82:1013-67.
    • (2002) Physiol Rev , vol.82 , pp. 1013-1067
    • North, R.A.1
  • 28
    • 0035881559 scopus 로고    scopus 로고
    • Cutting edge: The nucleotide receptor P2X7 contains multiple protein-and lipid-interaction motifs including a potential binding site for bacterial lipopolysaccharide
    • Denlinger LC, Fisette PL, Sommer JA, Watters JJ, Prabhu U, Dubyak GR, Proctor RA, Bertics PJ. Cutting edge: the nucleotide receptor P2X7 contains multiple protein-and lipid-interaction motifs including a potential binding site for bacterial lipopolysaccharide. J Immunol. 2001;167:1871-6.
    • (2001) J Immunol , vol.167 , pp. 1871-1876
    • Denlinger, L.C.1    Fisette, P.L.2    Sommer, J.A.3    Watters, J.J.4    Prabhu, U.5    Dubyak, G.R.6    Proctor, R.A.7    Bertics, P.J.8
  • 29
    • 0030743143 scopus 로고    scopus 로고
    • Properties of the pore-forming P2X7 purinoceptor in mouse NTW8 microglial cells
    • Chessell IP, Michel AD, Humphrey PP. Properties of the pore-forming P2X7 purinoceptor in mouse NTW8 microglial cells. Br J Pharmacol. 1997;121:1429-37.
    • (1997) Br J Pharmacol , vol.121 , pp. 1429-1437
    • Chessell, I.P.1    Michel, A.D.2    Humphrey, P.P.3
  • 30
    • 0038143359 scopus 로고    scopus 로고
    • P2X7 mediates superoxide production in primary microglia and is up-regulated in a transgenic mouse model of Alzheimer's disease
    • Parvathenani LK, Tertyshnikova S, Greco CR, Roberts SB, Robertson B, Posmantur R. P2X7 mediates superoxide production in primary microglia and is up-regulated in a transgenic mouse model of Alzheimer's disease. J Biol Chem. 2003; 278:13309-17.
    • (2003) J Biol Chem , vol.278 , pp. 13309-13317
    • Parvathenani, L.K.1    Tertyshnikova, S.2    Greco, C.R.3    Roberts, S.B.4    Robertson, B.5    Posmantur, R.6
  • 32
    • 0141884377 scopus 로고    scopus 로고
    • P2X7 nucleotide receptor activation enhances IFNγ-induced type II nitric oxide synthase activity in BV-2 microglial cells
    • Gendron FP, Chalimoniuk M, Strosznajder J, Shen S, Gonzalez FA, Weisman GA, Sun GY. P2X7 nucleotide receptor activation enhances IFNγ-induced type II nitric oxide synthase activity in BV-2 microglial cells. J Neurochem. 2003;87:344-52.
    • (2003) J Neurochem , vol.87 , pp. 344-352
    • Gendron, F.P.1    Chalimoniuk, M.2    Strosznajder, J.3    Shen, S.4    Gonzalez, F.A.5    Weisman, G.A.6    Sun, G.Y.7
  • 33
    • 0033051323 scopus 로고    scopus 로고
    • P2Z purinoreceptor ligation induces activation of caspases with distinct roles in apoptotic and necrotic alterations of cell death
    • Ferrari D, Los M, Bauer MK, Vandenabeele P, Wesselborg S, Schulze-Osthoff K. P2Z purinoreceptor ligation induces activation of caspases with distinct roles in apoptotic and necrotic alterations of cell death. FEBS Lett. 1999;447:71-5.
    • (1999) FEBS Lett , vol.447 , pp. 71-75
    • Ferrari, D.1    Los, M.2    Bauer, M.K.3    Vandenabeele, P.4    Wesselborg, S.5    Schulze-Osthoff, K.6
  • 35
    • 3042800587 scopus 로고    scopus 로고
    • Phospholipases C and A2 control lysosome-mediated IL-1β secretion: Implications for inflammatory processes
    • Andrei C, Margiocco P, Poggi A, Lotti LV, Torrisi MR, Rubartelli A. Phospholipases C and A2 control lysosome-mediated IL-1β secretion: Implications for inflammatory processes. Proc Natl Acad Sci U S A. 2004;101:9745-50.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 9745-9750
    • Andrei, C.1    Margiocco, P.2    Poggi, A.3    Lotti, L.V.4    Torrisi, M.R.5    Rubartelli, A.6
  • 36
    • 1942422683 scopus 로고    scopus 로고
    • Mechanisms of caspase-1 activation by P2X7 receptor-mediated K+ release
    • Kahlenberg JM, Dubyak GR. Mechanisms of caspase-1 activation by P2X7 receptor-mediated K+ release. Am J Physiol Cell Physiol. 2004;286:C1100-8.
    • (2004) Am J Physiol Cell Physiol , vol.286
    • Kahlenberg, J.M.1    Dubyak, G.R.2
  • 37
    • 0042242912 scopus 로고    scopus 로고
    • Essential role for Ca2+ in regulation of IL-1β secretion by P2X7 nucleotide receptor in monocytes, macrophages, and HEK-293 cells
    • Gudipaty L, Munetz J, Verhoef PA, Dubyak GR. Essential role for Ca2+ in regulation of IL-1β secretion by P2X7 nucleotide receptor in monocytes, macrophages, and HEK-293 cells. Am J Physiol Cell Physiol. 2003;285:C286-99.
    • (2003) Am J Physiol Cell Physiol , vol.285
    • Gudipaty, L.1    Munetz, J.2    Verhoef, P.A.3    Dubyak, G.R.4
  • 38
    • 0032923377 scopus 로고    scopus 로고
    • The secretory route of the leaderless protein interleukin 1β involves exocytosis of endolysosome-related vesicles
    • Andrei C, Dazzi C, Lotti L, Torrisi MR, Chimini G, Rubartelli A. The secretory route of the leaderless protein interleukin 1β involves exocytosis of endolysosome-related vesicles. Mol Biol Cell. 1999;10:1463-75.
    • (1999) Mol Biol Cell , vol.10 , pp. 1463-1475
    • Andrei, C.1    Dazzi, C.2    Lotti, L.3    Torrisi, M.R.4    Chimini, G.5    Rubartelli, A.6
  • 39
    • 3142660196 scopus 로고    scopus 로고
    • IL-1β: An endosomal exit
    • Wewers MD. IL-1β: an endosomal exit. Proc Natl Acad Sci U S A. 2004;101:10241-2.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 10241-10242
    • Wewers, M.D.1
  • 40
    • 33747191203 scopus 로고    scopus 로고
    • The inflammasome: First line of the immune response to cell stress
    • Ogura Y, Sutterwala FS, Flavell RA. The inflammasome: first line of the immune response to cell stress. Cell. 2006;126:659-62.
    • (2006) Cell , vol.126 , pp. 659-662
    • Ogura, Y.1    Sutterwala, F.S.2    Flavell, R.A.3
  • 42
    • 34047179487 scopus 로고    scopus 로고
    • Caspase-1-dependent processing of pro-interleukin-1β is cytosolic and precedes cell death
    • Brough D, Rothwell NJ. Caspase-1-dependent processing of pro-interleukin-1β is cytosolic and precedes cell death. J Cell Sci. 2007;120:772-81.
    • (2007) J Cell Sci , vol.120 , pp. 772-781
    • Brough, D.1    Rothwell, N.J.2
  • 43
    • 34548614009 scopus 로고    scopus 로고
    • Nonclassical IL-1β secretion stimulated by P2X7 receptors is dependent on inflammasome activation and correlated with exosome release in murine macrophages
    • Qu Y, Franchi L, Nunez G, Dubyak GR. Nonclassical IL-1β secretion stimulated by P2X7 receptors is dependent on inflammasome activation and correlated with exosome release in murine macrophages. J Immunol. 2007;179:1913-25.
    • (2007) J Immunol , vol.179 , pp. 1913-1925
    • Qu, Y.1    Franchi, L.2    Nunez, G.3    Dubyak, G.R.4
  • 46
    • 50949128076 scopus 로고    scopus 로고
    • Lysophospholipids and ATP Mutually Suppress Maturation and Release of IL-1β in Mouse Microglial Cells Using a Rho-Dependent Pathway
    • Takenouchi T, Iwamaru Y, Sugama S, Sato M, Hashimoto M, Kitani H. Lysophospholipids and ATP Mutually Suppress Maturation and Release of IL-1β in Mouse Microglial Cells Using a Rho-Dependent Pathway. J Immunol. 2008;180:7827-39.
    • (2008) J Immunol , vol.180 , pp. 7827-7839
    • Takenouchi, T.1    Iwamaru, Y.2    Sugama, S.3    Sato, M.4    Hashimoto, M.5    Kitani, H.6
  • 47
    • 27644520207 scopus 로고    scopus 로고
    • Inhibitory effects of U73122 and U73343 on Ca2+ influx and pore formation induced by the activation of P2X7 nucleotide receptors in mouse microglial cell line
    • Takenouchi T, Ogihara K, Sato M, Kitani H. Inhibitory effects of U73122 and U73343 on Ca2+ influx and pore formation induced by the activation of P2X7 nucleotide receptors in mouse microglial cell line. Biochim Biophys Acta. 2005;1726:177-86.
    • (2005) Biochim Biophys Acta , vol.1726 , pp. 177-186
    • Takenouchi, T.1    Ogihara, K.2    Sato, M.3    Kitani, H.4
  • 48
    • 34250220190 scopus 로고    scopus 로고
    • Lysophosphatidylcholine potentiates Ca2+ influx, pore formation and p44/42 MAP kinase phosphorylation mediated by P2X7 receptor activation in mouse microglial cells
    • Takenouchi T, Sato M, Kitani H. Lysophosphatidylcholine potentiates Ca2+ influx, pore formation and p44/42 MAP kinase phosphorylation mediated by P2X7 receptor activation in mouse microglial cells. J Neurochem. 2007; 102:1518-32.
    • (2007) J Neurochem , vol.102 , pp. 1518-1532
    • Takenouchi, T.1    Sato, M.2    Kitani, H.3
  • 50
    • 33748745943 scopus 로고    scopus 로고
    • Suppressive effect of simvastatin on interferon-β-induced expression of CC chemokine ligand 5 in microglia
    • Nakamichi K, Saiki M, Kitani H, Kuboyama Y, Morimoto K, Takayama-Ito M, Kurane I. Suppressive effect of simvastatin on interferon-β-induced expression of CC chemokine ligand 5 in microglia. Neurosci Lett. 2006;407:205-10.
    • (2006) Neurosci Lett , vol.407 , pp. 205-210
    • Nakamichi, K.1    Saiki, M.2    Kitani, H.3    Kuboyama, Y.4    Morimoto, K.5    Takayama-Ito, M.6    Kurane, I.7
  • 51
    • 33847229036 scopus 로고    scopus 로고
    • Roles of NF-κB and MAPK signaling pathways in morphological and cytoskeletal responses of microglia to double-stranded RNA
    • Nakamichi K, Saiki M, Kitani H, Kuboyama Y, Morimoto K, Takayama-Ito M, Kurane I. Roles of NF-κB and MAPK signaling pathways in morphological and cytoskeletal responses of microglia to double-stranded RNA. Neurosci Lett. 2007;414:222-7.
    • (2007) Neurosci Lett , vol.414 , pp. 222-227
    • Nakamichi, K.1    Saiki, M.2    Kitani, H.3    Kuboyama, Y.4    Morimoto, K.5    Takayama-Ito, M.6    Kurane, I.7
  • 52
    • 35348909573 scopus 로고    scopus 로고
    • Agonist potency at P2X7 receptors is modulated by structurally diverse lipids
    • Michel AD, Fonfria E. Agonist potency at P2X7 receptors is modulated by structurally diverse lipids. Br J Pharmacol. 2007;152:523-37.
    • (2007) Br J Pharmacol , vol.152 , pp. 523-537
    • Michel, A.D.1    Fonfria, E.2
  • 53
    • 33845422977 scopus 로고    scopus 로고
    • Lysophosphatidylcholine stimulates IL-1β release from microglia via a P2X7 receptor-independent mechanism
    • Stock C, Schilling T, Schwab A, Eder C. Lysophosphatidylcholine stimulates IL-1β release from microglia via a P2X7 receptor-independent mechanism. J Immunol. 2006;177:8560-8.
    • (2006) J Immunol , vol.177 , pp. 8560-8568
    • Stock, C.1    Schilling, T.2    Schwab, A.3    Eder, C.4
  • 57
    • 33746048017 scopus 로고    scopus 로고
    • Lysophosphatidylcholine reduces the organ injury and dysfunction in rodent models of gram-negative and gram-positive shock
    • Murch O, Collin M, Sepodes B, Foster SJ, Mota-Filipe H, Thiemermann C. Lysophosphatidylcholine reduces the organ injury and dysfunction in rodent models of gram-negative and gram-positive shock. Br J Pharmacol. 2006;148:769-77.
    • (2006) Br J Pharmacol , vol.148 , pp. 769-777
    • Murch, O.1    Collin, M.2    Sepodes, B.3    Foster, S.J.4    Mota-Filipe, H.5    Thiemermann, C.6
  • 58
    • 33750601018 scopus 로고    scopus 로고
    • Upregulated expression of purinergic P2X7 receptor in Alzheimer disease and amyloid-β peptide-treated microglia and in peptide-injected rat hippocampus
    • McLarnon JG, Ryu JK, Walker DG, Choi HB. Upregulated expression of purinergic P2X7 receptor in Alzheimer disease and amyloid-β peptide-treated microglia and in peptide-injected rat hippocampus. J Neuropathol Exp Neurol. 2006;65:1090-7.
    • (2006) J Neuropathol Exp Neurol , vol.65 , pp. 1090-1097
    • McLarnon, J.G.1    Ryu, J.K.2    Walker, D.G.3    Choi, H.B.4
  • 59
    • 33645224970 scopus 로고    scopus 로고
    • COX-2, CB2 and P2X7-immunoreactivities are increased in activated microglial cells/macrophages of multiple sclerosis and amyotrophic lateral sclerosis spinal cord
    • Yiangou Y, Facer P, Durrenberger P, Chessell IP, Naylor A, Bountra C, Banati RR, Anand P. COX-2, CB2 and P2X7-immunoreactivities are increased in activated microglial cells/macrophages of multiple sclerosis and amyotrophic lateral sclerosis spinal cord. BMC Neurol. 2006;6:12.
    • (2006) BMC Neurol , vol.6 , pp. 12
    • Yiangou, Y.1    Facer, P.2    Durrenberger, P.3    Chessell, I.P.4    Naylor, A.5    Bountra, C.6    Banati, R.R.7    Anand, P.8
  • 61
    • 56749085777 scopus 로고    scopus 로고
    • Block of purinergic P2X7 receptor is neuroprotective in an animal model of Alzheimer's disease
    • Ryu JK, McLarnon JG. Block of purinergic P2X7 receptor is neuroprotective in an animal model of Alzheimer's disease. Neuroreport. 2008;19: 1715-9.
    • (2008) Neuroreport , vol.19 , pp. 1715-1719
    • Ryu, J.K.1    McLarnon, J.G.2
  • 62
    • 34247868178 scopus 로고    scopus 로고
    • Modulation of the purinergic P2X7 receptor attenuates lipopolysaccharide-mediated microglial activation and neuronal damage in inflamed brain
    • Choi HB, Ryu JK, Kim SU, McLarnon JG. Modulation of the purinergic P2X7 receptor attenuates lipopolysaccharide-mediated microglial activation and neuronal damage in inflamed brain. J Neurosci. 2007;27:4957-68.
    • (2007) J Neurosci , vol.27 , pp. 4957-4968
    • Choi, H.B.1    Ryu, J.K.2    Kim, S.U.3    McLarnon, J.G.4
  • 63
    • 2642512455 scopus 로고    scopus 로고
    • The nucleotide receptor P2X7 mediates actin reorganization and membrane blebbing in RAW 264.7 macrophages via p38 MAP kinase and Rho
    • Pfeiffer ZA, Aga M, Prabhu U, Watters JJ, Hall DJ, Bertics PJ. The nucleotide receptor P2X7 mediates actin reorganization and membrane blebbing in RAW 264.7 macrophages via p38 MAP kinase and Rho. J Leukoc Biol. 2004;75:1173-82.
    • (2004) J Leukoc Biol , vol.75 , pp. 1173-1182
    • Pfeiffer, Z.A.1    Aga, M.2    Prabhu, U.3    Watters, J.J.4    Hall, D.J.5    Bertics, P.J.6
  • 64
    • 0036615827 scopus 로고    scopus 로고
    • Update on colchicine and its mechanism of action
    • Molad Y. Update on colchicine and its mechanism of action. Curr Rheumatol Rep 2002;4:252-6.
    • (2002) Curr Rheumatol Rep , vol.4 , pp. 252-256
    • Molad, Y.1
  • 65
    • 0013681996 scopus 로고
    • The Effect of Pretreatment with Colchicine on the Inflammatory Response to Microcrystalline Urate: A Model for Gouty Inflammation
    • Malawista SE, Seegmiller JE. The Effect of Pretreatment with Colchicine on the Inflammatory Response to Microcrystalline Urate: A Model for Gouty Inflammation. Ann Intern Med. 1965;62: 648-57.
    • (1965) Ann Intern Med , vol.62 , pp. 648-657
    • Malawista, S.E.1    Seegmiller, J.E.2
  • 66
    • 32944468985 scopus 로고    scopus 로고
    • Gout-associated uric acid crystals activate the NALP3 inflammasome
    • Martinon F, Petrilli V, Mayor A, Tardivel A, Tschopp J. Gout-associated uric acid crystals activate the NALP3 inflammasome. Nature. 2006;440:237-41.
    • (2006) Nature , vol.440 , pp. 237-241
    • Martinon, F.1    Petrilli, V.2    Mayor, A.3    Tardivel, A.4    Tschopp, J.5
  • 72
    • 67650273880 scopus 로고    scopus 로고
    • The role of the P2X7 receptor signaling pathway for the release of autolysosomes in microglial cells
    • Takenouchi T, Fujita M, Sugama S, Kitani H, Hashimoto M. The role of the P2X7 receptor signaling pathway for the release of autolysosomes in microglial cells. Autophagy. 2009;5:723-4.
    • (2009) Autophagy , vol.5 , pp. 723-724
    • Takenouchi, T.1    Fujita, M.2    Sugama, S.3    Kitani, H.4    Hashimoto, M.5
  • 73
    • 48449094878 scopus 로고    scopus 로고
    • ATP-induced autophagy is associated with rapid killing of intracellular mycobacteria within human monocytes/macrophages
    • Biswas D, Qureshi OS, Lee WY, Croudace JE, Mura M, Lammas DA. ATP-induced autophagy is associated with rapid killing of intracellular mycobacteria within human monocytes/macrophages. BMC Immunol. 2008;9:35.
    • (2008) BMC Immunol , vol.9 , pp. 35
    • Biswas, D.1    Qureshi, O.S.2    Lee, W.Y.3    Croudace, J.E.4    Mura, M.5    Lammas, D.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.